PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build -
PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build
PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build
PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions
| Official URL: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/ConceptMap/dm-immunological-data-to-fhir | Version: 0.1.0-ci-build | |||
| Draft as of 2026-09-28 | Computable Name: DmImmunologicalDataToFhir | |||
Maps each result column of the DMv1.2 immunological_data table to the code of the resource it becomes. The row itself becomes an ImmunologicalDataReport, and the biopsy columns a GraftBiopsy carrying the same immunological_data_id. Three columns have no code of their own: if becomes GraftBiopsy.conclusion, c4d becomes C4dStain.note, and the free text of pre_transplant_anti_hla_dsa becomes AntiHlaAntibodyScreen.note. The HLA columns are marked wider because each maps to a locus code shared by both allele columns: one Observation per allele replaces the ordered pair of slots.
Mapping from PROTECT-CHILD DM immunological_data variables to (not specified)
Group 1 Mapping from PROTECT-CHILD Data Model Variables to Logical Observation Identifiers, Names and Codes (LOINC)
| Source Code | Relationship | Target Code | Comment |
| immunological_data.blood_group | is equivalent to | 883-9 (ABO group [Type] in Blood) | BloodGroupObservation.code |
| immunological_data.rh_factor | is equivalent to | 10331-7 (Rh [Type] in Blood) | BloodGroupObservation.code |
| immunological_data.hla_a_1 | maps to wider concept | 13298-5 (HLA-A [Type]) | HlaTyping.code. One Observation per allele: hla_a_1 and hla_a_2 become two HlaTyping resources with the same code, since HLA alleles are not ordered. Use 57290-9 or 78014-8 where the typing resolution is known. |
| immunological_data.hla_a_2 | maps to wider concept | 13298-5 (HLA-A [Type]) | HlaTyping.code. See hla_a_1. |
| immunological_data.hla_b_1 | maps to wider concept | 13299-3 (HLA-B [Type]) | HlaTyping.code. Use 57291-7 or 78015-5 where the resolution is known. |
| immunological_data.hla_b_2 | maps to wider concept | 13299-3 (HLA-B [Type]) | HlaTyping.code. See hla_b_1. |
| immunological_data.hla_c_1 | maps to wider concept | 13302-5 (HLA-C [Type]) | HlaTyping.code. Use 77636-9 or 96636-6 where the resolution is known. |
| immunological_data.hla_c_2 | maps to wider concept | 13302-5 (HLA-C [Type]) | HlaTyping.code. See hla_c_1. |
| immunological_data.hla_drb1_1 | maps to wider concept | 57298-2 (HLA-DRB1 [Type]) | HlaTyping.code. Use 57293-3 or 96664-8 where the resolution is known. |
| immunological_data.hla_drb1_2 | maps to wider concept | 57298-2 (HLA-DRB1 [Type]) | HlaTyping.code. See hla_drb1_1. |
| immunological_data.hla_dp_1 | maps to wider concept | 12285-3 (HLA-DP [Type]) | HlaTyping.code. The DM values are DPB1 alleles at an unrecorded resolution, so the ambiguous DP code is the safe migration target; new data SHOULD use 59017-4 (DPB1 high resolution) or 96648-1 (low resolution). |
| immunological_data.hla_dp_2 | maps to wider concept | 12285-3 (HLA-DP [Type]) | HlaTyping.code. See hla_dp_1. |
| immunological_data.hla_dqb1_1 | maps to wider concept | 53938-7 (HLA-DQB1 [Type]) | HlaTyping.code. Use 57299-0 or 78017-1 where the resolution is known. |
| immunological_data.hla_dqb1_2 | maps to wider concept | 53938-7 (HLA-DQB1 [Type]) | HlaTyping.code. See hla_dqb1_1. |
| immunological_data.anti_hla_antibodies | is equivalent to | 44534-6 (HLA Ab [Presence] in Serum) | AntiHlaAntibodyScreen.code. The DM boolean becomes a Positive or Negative result, so a negative screen is recorded rather than inferred from absence. |
| immunological_data.pre_transplant_anti_hla_dsa | narrower | 107913-6 (HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Presence] in Serum or Plasma) | AntiHlaAntibodyScreen.code, with the DM free text in AntiHlaAntibodyScreen.note. |
| immunological_data.antibody_type | narrower | 107914-4 (HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Identifier] in Serum or Plasma) | AntiHlaAntibody.code; the target HLA specificity becomes AntiHlaAntibody.valueString, one Observation per antibody. Use 98006-0 for an antibody that is not donor-specific. |
| immunological_data.ihc_if_c4d | is equivalent to | 49461-7 (C4d Ag [Presence] in Tissue by Immune stain) | C4dStain.code. The DM boolean maps to BanffC4dScoreCS c4d-0 (false) or c4d-1..c4d-3 (true). |
| immunological_data.anca | is equivalent to | 17351-8 (Neutrophil cytoplasmic Ab [Presence] in Serum) | AncaObservation.code. The DM boolean becomes Positive or Negative. |
Group 2 Mapping from PROTECT-CHILD Data Model Variables to Immunological Data Component Codes
| Source Code | Relationship | Target Code | Comment |
| immunological_data.post_transplant_ab_anti_hla_dsa_class | is equivalent to | hla-class (HLA class of the antibody) | AntiHlaAntibody.component[hla_class].code. LOINC has no component code for antibody class. |
| immunological_data.mfi | is equivalent to | mfi-category (MFI band) | AntiHlaAntibody.component[mfi_category].code. The measured MFI, where the laboratory reports it, goes in component[mfi_value]. |
Group 3 Mapping from PROTECT-CHILD Data Model Variables to Graft Pathology Codes
| Source Code | Relationship | Target Code | Comment |
| immunological_data.banff_category | is equivalent to | banff-category (Banff diagnostic category) | BanffAssessment.code, on the GraftBiopsy built from the same DM row. Neither LOINC nor SNOMED CT carries the Banff classification. |