PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build -
PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build
PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build
PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions
| Draft as of 2026-09-28 |
{
"resourceType" : "ConceptMap",
"id" : "dm-immunological-data-to-fhir",
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ConceptMap dm-immunological-data-to-fhir</b></p><a name=\"dm-immunological-data-to-fhir\"> </a><a name=\"hcdm-immunological-data-to-fhir\"> </a><p>Mapping from <a href=\"ValueSet-dm-immunological-data-variable-vs.html\">PROTECT-CHILD DM immunological_data variables</a> to (not specified)</p><br/><p><b>Group 1 </b>Mapping from <a href=\"CodeSystem-dm-variable-cs.html\">PROTECT-CHILD Data Model Variables</a> to <a href=\"http://terminology.hl7.org/6.3.0/CodeSystem-v3-loinc.html\">Logical Observation Identifiers, Names and Codes (LOINC)</a></p><table class=\"grid\"><tr><td><b>Source Code</b></td><td><b>Relationship</b></td><td><b>Target Code</b></td><td><b>Comment</b></td></tr><tr><td>immunological_data.blood_group</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent\" title=\"equivalent\">is equivalent to</a></td><td>883-9 (ABO group [Type] in Blood)</td><td>BloodGroupObservation.code</td></tr><tr><td>immunological_data.rh_factor</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent\" title=\"equivalent\">is equivalent to</a></td><td>10331-7 (Rh [Type] in Blood)</td><td>BloodGroupObservation.code</td></tr><tr><td>immunological_data.hla_a_1</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>13298-5 (HLA-A [Type])</td><td>HlaTyping.code. One Observation per allele: hla_a_1 and hla_a_2 become two HlaTyping resources with the same code, since HLA alleles are not ordered. Use 57290-9 or 78014-8 where the typing resolution is known.</td></tr><tr><td>immunological_data.hla_a_2</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>13298-5 (HLA-A [Type])</td><td>HlaTyping.code. See hla_a_1.</td></tr><tr><td>immunological_data.hla_b_1</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>13299-3 (HLA-B [Type])</td><td>HlaTyping.code. Use 57291-7 or 78015-5 where the resolution is known.</td></tr><tr><td>immunological_data.hla_b_2</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>13299-3 (HLA-B [Type])</td><td>HlaTyping.code. See hla_b_1.</td></tr><tr><td>immunological_data.hla_c_1</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>13302-5 (HLA-C [Type])</td><td>HlaTyping.code. Use 77636-9 or 96636-6 where the resolution is known.</td></tr><tr><td>immunological_data.hla_c_2</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>13302-5 (HLA-C [Type])</td><td>HlaTyping.code. See hla_c_1.</td></tr><tr><td>immunological_data.hla_drb1_1</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>57298-2 (HLA-DRB1 [Type])</td><td>HlaTyping.code. Use 57293-3 or 96664-8 where the resolution is known.</td></tr><tr><td>immunological_data.hla_drb1_2</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>57298-2 (HLA-DRB1 [Type])</td><td>HlaTyping.code. See hla_drb1_1.</td></tr><tr><td>immunological_data.hla_dp_1</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>12285-3 (HLA-DP [Type])</td><td>HlaTyping.code. The DM values are DPB1 alleles at an unrecorded resolution, so the ambiguous DP code is the safe migration target; new data SHOULD use 59017-4 (DPB1 high resolution) or 96648-1 (low resolution).</td></tr><tr><td>immunological_data.hla_dp_2</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>12285-3 (HLA-DP [Type])</td><td>HlaTyping.code. See hla_dp_1.</td></tr><tr><td>immunological_data.hla_dqb1_1</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>53938-7 (HLA-DQB1 [Type])</td><td>HlaTyping.code. Use 57299-0 or 78017-1 where the resolution is known.</td></tr><tr><td>immunological_data.hla_dqb1_2</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider\" title=\"wider\">maps to wider concept</a></td><td>53938-7 (HLA-DQB1 [Type])</td><td>HlaTyping.code. See hla_dqb1_1.</td></tr><tr><td>immunological_data.anti_hla_antibodies</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent\" title=\"equivalent\">is equivalent to</a></td><td>44534-6 (HLA Ab [Presence] in Serum)</td><td>AntiHlaAntibodyScreen.code. The DM boolean becomes a Positive or Negative result, so a negative screen is recorded rather than inferred from absence.</td></tr><tr><td>immunological_data.pre_transplant_anti_hla_dsa</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-narrower\" title=\"narrower\">narrower</a></td><td>107913-6 (HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Presence] in Serum or Plasma)</td><td>AntiHlaAntibodyScreen.code, with the DM free text in AntiHlaAntibodyScreen.note.</td></tr><tr><td>immunological_data.antibody_type</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-narrower\" title=\"narrower\">narrower</a></td><td>107914-4 (HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Identifier] in Serum or Plasma)</td><td>AntiHlaAntibody.code; the target HLA specificity becomes AntiHlaAntibody.valueString, one Observation per antibody. Use 98006-0 for an antibody that is not donor-specific.</td></tr><tr><td>immunological_data.ihc_if_c4d</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent\" title=\"equivalent\">is equivalent to</a></td><td>49461-7 (C4d Ag [Presence] in Tissue by Immune stain)</td><td>C4dStain.code. The DM boolean maps to BanffC4dScoreCS c4d-0 (false) or c4d-1..c4d-3 (true).</td></tr><tr><td>immunological_data.anca</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent\" title=\"equivalent\">is equivalent to</a></td><td>17351-8 (Neutrophil cytoplasmic Ab [Presence] in Serum)</td><td>AncaObservation.code. The DM boolean becomes Positive or Negative.</td></tr></table><hr/><p><b>Group 2 </b>Mapping from <a href=\"CodeSystem-dm-variable-cs.html\">PROTECT-CHILD Data Model Variables</a> to <a href=\"CodeSystem-imm-data-component-cs.html\">Immunological Data Component Codes</a></p><table class=\"grid\"><tr><td><b>Source Code</b></td><td><b>Relationship</b></td><td><b>Target Code</b></td><td><b>Comment</b></td></tr><tr><td>immunological_data.post_transplant_ab_anti_hla_dsa_class</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent\" title=\"equivalent\">is equivalent to</a></td><td>hla-class (HLA class of the antibody)</td><td>AntiHlaAntibody.component[hla_class].code. LOINC has no component code for antibody class.</td></tr><tr><td>immunological_data.mfi</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent\" title=\"equivalent\">is equivalent to</a></td><td>mfi-category (MFI band)</td><td>AntiHlaAntibody.component[mfi_category].code. The measured MFI, where the laboratory reports it, goes in component[mfi_value].</td></tr></table><hr/><p><b>Group 3 </b>Mapping from <a href=\"CodeSystem-dm-variable-cs.html\">PROTECT-CHILD Data Model Variables</a> to <a href=\"CodeSystem-graft-pathology-cs.html\">Graft Pathology Codes</a></p><table class=\"grid\"><tr><td><b>Source Code</b></td><td><b>Relationship</b></td><td><b>Target Code</b></td><td><b>Comment</b></td></tr><tr><td>immunological_data.banff_category</td><td><a href=\"http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent\" title=\"equivalent\">is equivalent to</a></td><td>banff-category (Banff diagnostic category)</td><td>BanffAssessment.code, on the GraftBiopsy built from the same DM row. Neither LOINC nor SNOMED CT carries the Banff classification.</td></tr></table></div>"
},
"url" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/ConceptMap/dm-immunological-data-to-fhir",
"version" : "0.1.0-ci-build",
"name" : "DmImmunologicalDataToFhir",
"title" : "DM immunological_data columns → FHIR codes",
"status" : "draft",
"experimental" : true,
"date" : "2026-09-28T06:51:47+00:00",
"publisher" : "Protect Child",
"contact" : [
{
"name" : "Protect Child",
"telecom" : [
{
"system" : "url",
"value" : "https://protect-child.eu/"
}
]
}
],
"description" : "Maps each result column of the DMv1.2 immunological_data table to the code of the resource it becomes. The row itself becomes an ImmunologicalDataReport, and the biopsy columns a GraftBiopsy carrying the same immunological_data_id. Three columns have no code of their own: `if` becomes GraftBiopsy.conclusion, `c4d` becomes C4dStain.note, and the free text of `pre_transplant_anti_hla_dsa` becomes AntiHlaAntibodyScreen.note. The HLA columns are marked `wider` because each maps to a locus code shared by both allele columns: one Observation per allele replaces the ordered pair of slots.",
"sourceCanonical" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/ValueSet/dm-immunological-data-variable-vs",
"group" : [
{
"source" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs",
"target" : "http://loinc.org",
"element" : [
{
"code" : "immunological_data.blood_group",
"target" : [
{
"code" : "883-9",
"display" : "ABO group [Type] in Blood",
"equivalence" : "equivalent",
"comment" : "BloodGroupObservation.code"
}
]
},
{
"code" : "immunological_data.rh_factor",
"target" : [
{
"code" : "10331-7",
"display" : "Rh [Type] in Blood",
"equivalence" : "equivalent",
"comment" : "BloodGroupObservation.code"
}
]
},
{
"code" : "immunological_data.hla_a_1",
"target" : [
{
"code" : "13298-5",
"display" : "HLA-A [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. One Observation per allele: hla_a_1 and hla_a_2 become two HlaTyping resources with the same code, since HLA alleles are not ordered. Use 57290-9 or 78014-8 where the typing resolution is known."
}
]
},
{
"code" : "immunological_data.hla_a_2",
"target" : [
{
"code" : "13298-5",
"display" : "HLA-A [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. See hla_a_1."
}
]
},
{
"code" : "immunological_data.hla_b_1",
"target" : [
{
"code" : "13299-3",
"display" : "HLA-B [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. Use 57291-7 or 78015-5 where the resolution is known."
}
]
},
{
"code" : "immunological_data.hla_b_2",
"target" : [
{
"code" : "13299-3",
"display" : "HLA-B [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. See hla_b_1."
}
]
},
{
"code" : "immunological_data.hla_c_1",
"target" : [
{
"code" : "13302-5",
"display" : "HLA-C [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. Use 77636-9 or 96636-6 where the resolution is known."
}
]
},
{
"code" : "immunological_data.hla_c_2",
"target" : [
{
"code" : "13302-5",
"display" : "HLA-C [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. See hla_c_1."
}
]
},
{
"code" : "immunological_data.hla_drb1_1",
"target" : [
{
"code" : "57298-2",
"display" : "HLA-DRB1 [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. Use 57293-3 or 96664-8 where the resolution is known."
}
]
},
{
"code" : "immunological_data.hla_drb1_2",
"target" : [
{
"code" : "57298-2",
"display" : "HLA-DRB1 [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. See hla_drb1_1."
}
]
},
{
"code" : "immunological_data.hla_dp_1",
"target" : [
{
"code" : "12285-3",
"display" : "HLA-DP [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. The DM values are DPB1 alleles at an unrecorded resolution, so the ambiguous DP code is the safe migration target; new data SHOULD use 59017-4 (DPB1 high resolution) or 96648-1 (low resolution)."
}
]
},
{
"code" : "immunological_data.hla_dp_2",
"target" : [
{
"code" : "12285-3",
"display" : "HLA-DP [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. See hla_dp_1."
}
]
},
{
"code" : "immunological_data.hla_dqb1_1",
"target" : [
{
"code" : "53938-7",
"display" : "HLA-DQB1 [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. Use 57299-0 or 78017-1 where the resolution is known."
}
]
},
{
"code" : "immunological_data.hla_dqb1_2",
"target" : [
{
"code" : "53938-7",
"display" : "HLA-DQB1 [Type]",
"equivalence" : "wider",
"comment" : "HlaTyping.code. See hla_dqb1_1."
}
]
},
{
"code" : "immunological_data.anti_hla_antibodies",
"target" : [
{
"code" : "44534-6",
"display" : "HLA Ab [Presence] in Serum",
"equivalence" : "equivalent",
"comment" : "AntiHlaAntibodyScreen.code. The DM boolean becomes a Positive or Negative result, so a negative screen is recorded rather than inferred from absence."
}
]
},
{
"code" : "immunological_data.pre_transplant_anti_hla_dsa",
"target" : [
{
"code" : "107913-6",
"display" : "HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Presence] in Serum or Plasma",
"equivalence" : "narrower",
"comment" : "AntiHlaAntibodyScreen.code, with the DM free text in AntiHlaAntibodyScreen.note."
}
]
},
{
"code" : "immunological_data.antibody_type",
"target" : [
{
"code" : "107914-4",
"display" : "HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Identifier] in Serum or Plasma",
"equivalence" : "narrower",
"comment" : "AntiHlaAntibody.code; the target HLA specificity becomes AntiHlaAntibody.valueString, one Observation per antibody. Use 98006-0 for an antibody that is not donor-specific."
}
]
},
{
"code" : "immunological_data.ihc_if_c4d",
"target" : [
{
"code" : "49461-7",
"display" : "C4d Ag [Presence] in Tissue by Immune stain",
"equivalence" : "equivalent",
"comment" : "C4dStain.code. The DM boolean maps to BanffC4dScoreCS c4d-0 (false) or c4d-1..c4d-3 (true)."
}
]
},
{
"code" : "immunological_data.anca",
"target" : [
{
"code" : "17351-8",
"display" : "Neutrophil cytoplasmic Ab [Presence] in Serum",
"equivalence" : "equivalent",
"comment" : "AncaObservation.code. The DM boolean becomes Positive or Negative."
}
]
}
]
},
{
"source" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs",
"target" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
"element" : [
{
"code" : "immunological_data.post_transplant_ab_anti_hla_dsa_class",
"target" : [
{
"code" : "hla-class",
"display" : "HLA class of the antibody",
"equivalence" : "equivalent",
"comment" : "AntiHlaAntibody.component[hla_class].code. LOINC has no component code for antibody class."
}
]
},
{
"code" : "immunological_data.mfi",
"target" : [
{
"code" : "mfi-category",
"display" : "MFI band",
"equivalence" : "equivalent",
"comment" : "AntiHlaAntibody.component[mfi_category].code. The measured MFI, where the laboratory reports it, goes in component[mfi_value]."
}
]
}
]
},
{
"source" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs",
"target" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/graft-pathology-cs",
"element" : [
{
"code" : "immunological_data.banff_category",
"target" : [
{
"code" : "banff-category",
"display" : "Banff diagnostic category",
"equivalence" : "equivalent",
"comment" : "BanffAssessment.code, on the GraftBiopsy built from the same DM row. Neither LOINC nor SNOMED CT carries the Banff classification."
}
]
}
]
}
]
}