PROTECT-CHILD Data Model Variables - PROTECT-CHILD Pediatric Transplant Data Implementation Guide v0.1.0-ci-build

PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions

CodeSystem: PROTECT-CHILD Data Model Variables (Experimental)

Official URL: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs				Version: 0.1.0-ci-build
Draft as of 2026-09-28				Computable Name: DmVariableCS

One code per PROTECT-CHILD data-model (DMv1.2) column, as table.column. Used as the source of the DM → FHIR code maps and the DM → OMOP ConceptMaps (codes for the latter are added by scripts/dm-omop-maps.py).

This Code system is referenced in the content logical definition of the following value sets:

This case-sensitive code system https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs defines the following codes:

Code	Definition
microbiology.ebv_dna	DMv1.2 column microbiology.ebv_dna: EBV nucleic acid test result.
microbiology.ebv_dna_copies	DMv1.2 column microbiology.ebv_dna_copies: EBV-DNA (copies/ml).
microbiology.ebv_igm_anti_ea	DMv1.2 column microbiology.ebv_igm_anti_ea: Presence of IgM antibodies against Epstein–Barr virus Early Antigen (EA).
microbiology.ebv_igm_anti_vca	DMv1.2 column microbiology.ebv_igm_anti_vca: Presence of IgM antibodies against EBV Viral Capsid Antigen (VCA).
microbiology.ebv_igg_anti_vca	DMv1.2 column microbiology.ebv_igg_anti_vca: Presence of IgG antibodies against EBV Viral Capsid Antigen (VCA).
microbiology.ebv_igg_ebna	DMv1.2 column microbiology.ebv_igg_ebna: Presence of IgG antibodies against EBV Nuclear Antigen (EBNA).
microbiology.cmv_dna	DMv1.2 column microbiology.cmv_dna: CMV nucleic acid test result.
microbiology.cmv_dna_copies	DMv1.2 column microbiology.cmv_dna_copies: CMV-DNA (copies/ml).
microbiology.cmv_igm	DMv1.2 column microbiology.cmv_igm: Presence of IgM antibodies against cytomegalovirus (CMV).
microbiology.cmv_igg	DMv1.2 column microbiology.cmv_igg: Presence of IgG antibodies against cytomegalovirus (CMV).
microbiology.parvovirus_b19_dna	DMv1.2 column microbiology.parvovirus_b19_dna: Detection of parvovirus B19 DNA in the patient’s blood.
microbiology.parvovirus_b19_dna_copies	DMv1.2 column microbiology.parvovirus_b19_dna_copies: Blood Parvovirus B19 DNA (copies/ml).
microbiology.parvovirus_b19_igg	DMv1.2 column microbiology.parvovirus_b19_igg: Presence of IgG antibodies to parvovirus B19.
microbiology.parvovirus_b19_igm	DMv1.2 column microbiology.parvovirus_b19_igm: Presence of IgM antibodies to parvovirus B19.
microbiology.hsv_igg	DMv1.2 column microbiology.hsv_igg: Presence of IgG antibodies to herpes simplex virus (HSV).
microbiology.hsv_igm	DMv1.2 column microbiology.hsv_igm: Presence of IgM antibodies to HSV.
microbiology.adenovirus_igg	DMv1.2 column microbiology.adenovirus_igg: Presence of IgG antibodies to adenovirus.
microbiology.adenovirus_igm	DMv1.2 column microbiology.adenovirus_igm: Presence of IgM antibodies to adenovirus.
microbiology.blood_adenovirus_dna	DMv1.2 column microbiology.blood_adenovirus_dna: Blood Adenovirus DNA Result.
microbiology.blood_adenovirus_dna_copies	DMv1.2 column microbiology.blood_adenovirus_dna_copies: Blood Adenovirus DNA (copies/ml).
microbiology.vzv_igg	DMv1.2 column microbiology.vzv_igg: Presence of IgG antibodies to varicella–zoster virus.
microbiology.vzv_igm	DMv1.2 column microbiology.vzv_igm: Presence of IgM antibodies to varicella–zoster virus.
microbiology.blood_bkv_dna	DMv1.2 column microbiology.blood_bkv_dna: Blood BKV-DNA.
microbiology.blood_bkv_dna_copies	DMv1.2 column microbiology.blood_bkv_dna_copies: Blood BKV-DNA (copies/ml).
microbiology.urine_bkv_dna	DMv1.2 column microbiology.urine_bkv_dna: Urine BKV-DNA.
microbiology.bkv_dna_kidney_biopsy	DMv1.2 column microbiology.bkv_dna_kidney_biopsy: BKV-DNA on kidney biopsy.
microbiology.bkv_fish_kidney_biopsy	DMv1.2 column microbiology.bkv_fish_kidney_biopsy: BKV FISH on kidney biopsy.
microbiology.blood_colture	DMv1.2 column microbiology.blood_colture: Blood colture.
microbiology.urine_colture	DMv1.2 column microbiology.urine_colture: Urine colture.
microbiology.other_positivity	DMv1.2 column microbiology.other_positivity: Other positivity.
microbiology.ebv_hepatitis_liver	DMv1.2 column microbiology.ebv_hepatitis_liver: EBV-Hepatitis on liver.
microbiology.evidence_bkvan	DMv1.2 column microbiology.evidence_bkvan: Histological evidence of BKVAN.
immunological_data.blood_group	DMv1.2 column immunological_data.blood_group: Patient ABO.
immunological_data.rh_factor	DMv1.2 column immunological_data.rh_factor: Patients RhD status.
immunological_data.hla_a_1	DMv1.2 column immunological_data.hla_a_1: HLA A (Allele 1).
immunological_data.hla_a_2	DMv1.2 column immunological_data.hla_a_2: HLA A (Allele 2).
immunological_data.hla_b_1	DMv1.2 column immunological_data.hla_b_1: HLA B (Allele 1).
immunological_data.hla_b_2	DMv1.2 column immunological_data.hla_b_2: HLA B (Allele 2).
immunological_data.hla_c_1	DMv1.2 column immunological_data.hla_c_1: HLA C (Allele 1).
immunological_data.hla_c_2	DMv1.2 column immunological_data.hla_c_2: HLA C (Allele 2).
immunological_data.hla_drb1_1	DMv1.2 column immunological_data.hla_drb1_1: HLA DRB1 (Allele 1).
immunological_data.hla_drb1_2	DMv1.2 column immunological_data.hla_drb1_2: HLA DRB1 (Allele 2).
immunological_data.hla_dp_1	DMv1.2 column immunological_data.hla_dp_1: HLA DP (Allele 1).
immunological_data.hla_dp_2	DMv1.2 column immunological_data.hla_dp_2: HLA DP (Allele 2).
immunological_data.hla_dqb1_1	DMv1.2 column immunological_data.hla_dqb1_1: HLA DQB1 (Allele 1).
immunological_data.hla_dqb1_2	DMv1.2 column immunological_data.hla_dqb1_2: HLA DQB1 (Allele 2).
immunological_data.post_transplant_ab_anti_hla_dsa_class	DMv1.2 column immunological_data.post_transplant_ab_anti_hla_dsa_class: Post-transplant Ab anti-HLA DSA (Class).
immunological_data.pre_transplant_anti_hla_dsa	DMv1.2 column immunological_data.pre_transplant_anti_hla_dsa.
immunological_data.mfi	DMv1.2 column immunological_data.mfi: MFI Category.
immunological_data.banff_category	DMv1.2 column immunological_data.banff_category: Banff category (Done?).
immunological_data.ihc_if_c4d	DMv1.2 column immunological_data.ihc_if_c4d: IHC/IF C4d (Result).
immunological_data.if	DMv1.2 column immunological_data.if: IF.
immunological_data.c4d	DMv1.2 column immunological_data.c4d: C4d.
immunological_data.anca	DMv1.2 column immunological_data.anca: ANCA.
immunological_data.antibody_type	DMv1.2 column immunological_data.antibody_type: Antibody Type (Specification).
immunological_data.anti_hla_antibodies	DMv1.2 column immunological_data.anti_hla_antibodies: Presence of anti-HLA antibodies.
patient.gender	DMv1.2 column patient.gender: Patient’s gender.
patient.max_pra	DMv1.2 column patient.max_pra: Maximum historical PRA/cPRA prior to transplant.
patient.last_pra	DMv1.2 column patient.last_pra: Most recent PRA/cPRA prior to transplant.
patient.date_histological_diag	DMv1.2 column patient.date_histological_diag: Earliest date a histology report confirmed the relevant primary disease.
patient.diag_primary_disease	DMv1.2 column patient.diag_primary_disease: Main liver disease leading to transplant.
donor.type	DMv1.2 column donor.type: Whether the donor was living or deceased.
donor.liver_type	DMv1.2 column donor.liver_type: Whole graft vs. partial/split graft.
visit.visit_type	DMv1.2 column visit.visit_type: Type of the visit as recorded in the CRF.
transplant.d_r_weight_ratio	DMv1.2 column transplant.d_r_weight_ratio: Donor graft weight divided by recipient body weight.
transplant.vessel_mismatch_d_r	DMv1.2 column transplant.vessel_mismatch_d_r: Any size/configuration mismatch of vessels requiring tailoring.
transplant.cold_ischemia_time	DMv1.2 column transplant.cold_ischemia_time: Minutes the graft stayed preserved on ice before implantation.
transplant.warm_ischemia_time	DMv1.2 column transplant.warm_ischemia_time: Minutes from the moment donor kidney blood flow stops to the start of cold preservation perfusion. For liver use this as the unique warm ischemia time.
transplant.tx_type	DMv1.2 column transplant.tx_type: Transplant type. Whether the patient will receive an isolated liver, isolated kidney or a combined transplant.
transplant.vascular_anomalies	DMv1.2 column transplant.vascular_anomalies: Presence of relevant arterial/venous anatomical variants (specify).
transplant.type_surgical_biliary_anastomosis	DMv1.2 column transplant.type_surgical_biliary_anastomosis: Bile duct reconstruction used (e.g., duct-to-duct, hepaticojejunostomy).
transplant.intraoperative_complications	DMv1.2 column transplant.intraoperative_complications: Whether complications occurred during surgery.
transplant.intraoperative_complications_other	DMv1.2 column transplant.intraoperative_complications_other: Specify whether other type of complications occurred during surgery.
transplant.type_ureteral_graft_anastomosis	DMv1.2 column transplant.type_ureteral_graft_anastomosis: Type of ureteral graft anastomosis.
transplant.other_type_ureteral_graft_anastomosis	DMv1.2 column transplant.other_type_ureteral_graft_anastomosis: Other type of ureteral graft anastomosis.
vital_sign.systolic_blood_pressure	DMv1.2 column vital_sign.systolic_blood_pressure: Systolic blood pressure (mmHg).
vital_sign.diastolic_blood_pressure	DMv1.2 column vital_sign.diastolic_blood_pressure: Diastolic blood pressure (mmHg).
vital_sign.heart_rate	DMv1.2 column vital_sign.heart_rate: Pulse rate.
vital_sign.oxygen_saturation	DMv1.2 column vital_sign.oxygen_saturation: Oxygen saturation at rest.
vital_sign.temperature	DMv1.2 column vital_sign.temperature: Body temperature.
vital_sign.bmi	DMv1.2 column vital_sign.bmi: BMI.
vital_sign.sbp_percentile	DMv1.2 column vital_sign.sbp_percentile: Systolic BP (mmHg).
vital_sign.dbp_percentile	DMv1.2 column vital_sign.dbp_percentile: Diastolic BP (mmHg).
vital_sign.mean_sbp_24	DMv1.2 column vital_sign.mean_sbp_24: Mean SBP – 24h (mmHg).
vital_sign.mean_dbp_24	DMv1.2 column vital_sign.mean_dbp_24: Mean DBP – 24h (mmHg).
vital_sign.mean_sbp_day	DMv1.2 column vital_sign.mean_sbp_day: Mean SBP – Daytime (mmHg).
vital_sign.mean_dbp_day	DMv1.2 column vital_sign.mean_dbp_day: Mean DBP – Daytime (mmHg).
vital_sign.mean_sbp_night	DMv1.2 column vital_sign.mean_sbp_night: Mean SBP – Night time (mmHg).
vital_sign.mean_dbp_night	DMv1.2 column vital_sign.mean_dbp_night: Mean DBP – Night time (mmHg).
vital_sign.sbp_load	DMv1.2 column vital_sign.sbp_load: SBP Load (%).
vital_sign.dbp_load	DMv1.2 column vital_sign.dbp_load: DBP Load (%).
vital_sign.sbp_dip	DMv1.2 column vital_sign.sbp_dip: SBP Dip (%).
vital_sign.dbp_dip	DMv1.2 column vital_sign.dbp_dip: DBP Dip (%).
bio_sample.collection_date	DMv1.2 column bio_sample.collection_date: Date when the sample was collected.
pre_medication.antihypertensive_treatment	DMv1.2 column pre_medication.antihypertensive_treatment: Any blood-pressure–lowering drugs used.
pre_medication.rituximab	DMv1.2 column pre_medication.rituximab: Any rituximab given pre-transplant.
pre_medication.antiviral_prophylaxis	DMv1.2 column pre_medication.antiviral_prophylaxis: Antiviral prophylaxis.
clinical_variable.weight	DMv1.2 column clinical_variable.weight: Patient’s weight.
clinical_variable.height	DMv1.2 column clinical_variable.height: Patient’s height.
clinical_variable.concomitant_disease	DMv1.2 column clinical_variable.concomitant_disease: Concomitant disease ID relationship.
clinical_variable.diuresis_value	DMv1.2 column clinical_variable.diuresis_value: Diuresis value (ml/day).
concomitant_medication.dose	DMv1.2 column concomitant_medication.dose.
concomitant_medication.status	DMv1.2 column concomitant_medication.status.
instrumental_investigation.instrumental_investigation	DMv1.2 column instrumental_investigation.instrumental_investigation: Instrumental investigation Name.
instrumental_investigation.result	DMv1.2 column instrumental_investigation.result: Result of the instrumental investigation.
immunosuppressant.name	DMv1.2 column immunosuppressant.name: Name of the immunosuppresant drug.
imm_pat.phase	DMv1.2 column imm_pat.phase: Phase.
imm_pat.dose	DMv1.2 column imm_pat.dose: Dose.
imm_pat.pre_dose_level	DMv1.2 column imm_pat.pre_dose_level: Trough drug concentration (C0): the level measured immediately before the next scheduled dose.
imm_pat.csa_2h_post_dose_level	DMv1.2 column imm_pat.csa_2h_post_dose_level: Cyclosporine C2 level: drug concentration measured ~2 hours after a cyclosporine dose.
imm_pat.auc	DMv1.2 column imm_pat.auc: Area-under-the-curve exposure for this agent when measured.
imm_pat.unit	DMv1.2 column imm_pat.unit: Unit for the selected immunosuppressant dose.
lab_test.name	DMv1.2 column lab_test.name: Name of the lab test conducted.
lab_result.unit	DMv1.2 column lab_result.unit: Unit measurement.
clinical_event_type.name	DMv1.2 column clinical_event_type.name: Clinical event type.
clinical_event.dgf	DMv1.2 column clinical_event.dgf: Delayed Graft Function.
clinical_event.vascular_complication_type	DMv1.2 column clinical_event.vascular_complication_type: Vascular Complication Type.
clinical_event.episodes_aki_after_ltx	DMv1.2 column clinical_event.episodes_aki_after_ltx: Episodes of AKI after LTx.
clinical_event.histologic_evidence_cni_toxicity	DMv1.2 column clinical_event.histologic_evidence_cni_toxicity: Histologic evidence of CNI toxicity.
clinical_event.hypoxic_ischemic_event_pltx	DMv1.2 column clinical_event.hypoxic_ischemic_event_pltx: Hypoxic ischemic events after pLTx.
clinical_event.dialysis_type	DMv1.2 column clinical_event.dialysis_type: Type (Dialysis).
clinical_event.treatment_adherence	DMv1.2 column clinical_event.treatment_adherence: Treatment adherence (Status).
clinical_event.date_entry_transplant_list	DMv1.2 column clinical_event.date_entry_transplant_list: Date of entry in transplant list.