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PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build -

PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build

PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions

Table of Contents

.. 0 Table of Contents
... 1 Home
... 2 Mapping
... 3 Logical Models
... 4 Data Model (ERD)
... 5 Artifacts Summary
.... 5.1 BioSample logical model
.... 5.2 ClinicalVariable logical model
.... 5.3 ConcomitantDisease logical model
.... 5.4 ConcomitantEpisode logical model
.... 5.5 ConcomitantMedication logical model
.... 5.6 Donor logical model
.... 5.7 EpigenomeStudy logical model
.... 5.8 GenomicTest logical model
.... 5.9 ImmIndPat logical model
.... 5.10 ImmMainPat logical model
.... 5.11 Immunosuppressant logical model
.... 5.12 InstrumentalInvestigation logical model
.... 5.13 LabResult logical model
.... 5.14 LabTest logical model
.... 5.15 MarkImmFunc logical model
.... 5.16 MethylomicStudy logical model
.... 5.17 Microbiology logical model
.... 5.18 Outcome logical model
.... 5.19 OutcomeType logical model
.... 5.20 Patient logical model
.... 5.21 PatInstInv logical model
.... 5.22 PostEvent logical model
.... 5.23 PostEventType logical model
.... 5.24 PreMedication logical model
.... 5.25 ReferenceGenome logical model
.... 5.26 TargetRegion logical model
.... 5.27 Transplant logical model
.... 5.28 Unit logical model
.... 5.29 VariantAnnotation logical model
.... 5.30 VariantOccurrence logical model
.... 5.31 Visit logical model
.... 5.32 ABO group observation
.... 5.33 Biological Sample
.... 5.34 Clinical Variable
.... 5.35 Concomitant Disease
.... 5.36 Concomitant Episode
.... 5.37 Concomitant Medication
.... 5.38 Donor liver graft type observation
.... 5.39 Donor pre-KTX dialysis type observation
.... 5.40 Epigenome Study
.... 5.41 Genomic Test
.... 5.42 Histological diagnosis date observation
.... 5.43 HLA Class I typing observation
.... 5.44 HLA Class II typing observation
.... 5.45 Immunosuppressant
.... 5.46 Immunosuppressant Induction to Patient
.... 5.47 Immunosuppressive Maintenance to Patient
.... 5.48 Instrumental Investigation
.... 5.49 Lab Result
.... 5.50 Lab Test
.... 5.51 Laboratory DiagnosticReport
.... 5.52 Liver disease diagnosis observation
.... 5.53 Marker of Immune Function
.... 5.54 Methylomic Study
.... 5.55 Microbiology
.... 5.56 Outcome
.... 5.57 Outcome Type
.... 5.58 Patient Instrumental Investigation
.... 5.59 Patient observations
.... 5.60 Post Event
.... 5.61 Post Event Type
.... 5.62 PRA observation
.... 5.63 Pre-transplant Medication
.... 5.64 Reference Genome
.... 5.65 Renal disease diagnosis observation
.... 5.66 Rh factor observation
.... 5.67 Target Region
.... 5.68 Transplant
.... 5.69 Transplant Donor
.... 5.70 Transplant Recipient
.... 5.71 Variant Annotation
.... 5.72 Variant Occurrence
.... 5.73 Visit
.... 5.74 2h post-dose drug level (C2)
.... 5.75 Adenovirus serology IgG
.... 5.76 Adenovirus serology IgM
.... 5.77 AECA / other non-HLA antibodies
.... 5.78 Age at DNA extraction
.... 5.79 Alignment tools
.... 5.80 Allele frequency
.... 5.81 Alternate allele
.... 5.82 Annotation database
.... 5.83 Annotation databases
.... 5.84 Annotation tools
.... 5.85 Anti-MICA antibody result
.... 5.86 Anti-MICB antibody result
.... 5.87 Antihypertensive treatment
.... 5.88 Antiviral prophylaxis pre-medication
.... 5.89 Area under the concentration–time curve (AUC)
.... 5.90 Array date
.... 5.91 AT1R antibody result
.... 5.92 Beta value
.... 5.93 BioSample ID relationship
.... 5.94 Bisulfite date
.... 5.95 Bisulfite reference kit
.... 5.96 BKV FISH on kidney biopsy
.... 5.97 BKV-DNA on kidney biopsy
.... 5.98 Blood BKV-DNA
.... 5.99 Blood CMV-DNA
.... 5.100 Blood EBV-DNA
.... 5.101 Blood Parvovirus B19-DNA
.... 5.102 Chip type
.... 5.103 Chromosome coordinate
.... 5.104 Chromosome ID
.... 5.105 Clinical variable ID relationship
.... 5.106 Clinical variable ID relationship
.... 5.107 CMV serology IgG
.... 5.108 CMV serology IgM
.... 5.109 CNV locus
.... 5.110 Cold ischaemia time (minutes)
.... 5.111 Concomitant disease ID relationship
.... 5.112 Concomitant disease name(s)
.... 5.113 Concomitant episode ID relationship
.... 5.114 Concomitant episode ID relationship
.... 5.115 Concomitant episode ID relationship
.... 5.116 Copy number
.... 5.117 Date
.... 5.118 Date of instrumental investigation
.... 5.119 dbSNP rsID
.... 5.120 Detection p-value
.... 5.121 Diastolic blood pressure
.... 5.122 DNA concentration
.... 5.123 Donor ID relationship
.... 5.124 Donor type
.... 5.125 Donor-specific antibody (DSA)
.... 5.126 Donor/recipient weight ratio
.... 5.127 Dose of immunosuppressant
.... 5.128 EBV serology IgG anti-VCA
.... 5.129 EBV serology IgG EBNA
.... 5.130 EBV serology IgM anti-EA
.... 5.131 EBV serology IgM anti-VCA
.... 5.132 End date of maintenance therapy
.... 5.133 End position
.... 5.134 Epigenome Study ID Relationship
.... 5.135 Episode date
.... 5.136 Episode description
.... 5.137 ETAR antibody result
.... 5.138 Event description
.... 5.139 Event end date
.... 5.140 Event onset date
.... 5.141 First warm ischaemia time (minutes)
.... 5.142 Fusion breakpoint
.... 5.143 Fusion supporting reads
.... 5.144 Genetic origin
.... 5.145 Genomic Test ID Relationship
.... 5.146 Genomic test ID relationship
.... 5.147 Genomic test ID relationship
.... 5.148 Genomic Test Name
.... 5.149 Genomic Test Version
.... 5.150 Genotype
.... 5.151 Heart rate
.... 5.152 Height
.... 5.153 HGNC ID
.... 5.154 HGNC symbol
.... 5.155 HGVS c. notation
.... 5.156 HGVS p. notation
.... 5.157 HLA antibody class or locus
.... 5.158 HSV serology IgG
.... 5.159 HSV serology IgM
.... 5.160 Immunosuppressant dose
.... 5.161 Immunosuppressant ID relationship
.... 5.162 Immunosuppressant ID relationship
.... 5.163 Immunosuppressant name
.... 5.164 Immunosuppressive induction ID relationship
.... 5.165 Immunosuppressive maintenance ID relationship
.... 5.166 Instrumental investigation ID relationship
.... 5.167 Instrumental investigation name
.... 5.168 Intraoperative complications
.... 5.169 Kidney side
.... 5.170 Lab result ID relationship
.... 5.171 Lab result patient reference
.... 5.172 Lab test ID relationship
.... 5.173 Lab test name
.... 5.174 Lab test reference
.... 5.175 M value
.... 5.176 Manifest number
.... 5.177 Mean target coverage
.... 5.178 Medication
.... 5.179 Medication
.... 5.180 Methylated reads
.... 5.181 Methylomic Study ID Relationship
.... 5.182 MFI value
.... 5.183 Microbiology ID relationship
.... 5.184 Microbiology ID relationship
.... 5.185 Nephrectomy of original kidney
.... 5.186 Other intraoperative complications (free text)
.... 5.187 Other pre-transplant medications
.... 5.188 Outcome date
.... 5.189 Outcome ID relationship
.... 5.190 Outcome type ID relationship
.... 5.191 Outcome type name
.... 5.192 Oxygen saturation
.... 5.193 Parvovirus B19 serology IgG
.... 5.194 Parvovirus B19 serology IgM
.... 5.195 Patient ID relationship
.... 5.196 Patient ID relationship
.... 5.197 Patient ID relationship
.... 5.198 Patient ID relationship
.... 5.199 Patient ID relationship
.... 5.200 Patient ID relationship
.... 5.201 Patient ID relationship
.... 5.202 Patient ID relationship
.... 5.203 Patient instrumental investigation ID relationship
.... 5.204 Patient instrumental investigation ID relationship
.... 5.205 Per target base cover x100
.... 5.206 Pool ID
.... 5.207 Post event ID relationship
.... 5.208 Post event type ID relationship
.... 5.209 Post event type name
.... 5.210 Post-event ID relationship
.... 5.211 Pre-dose drug level
.... 5.212 Pre-medication ID relationship
.... 5.213 Pre-medication ID relationship
.... 5.214 Pre-medication patient reference
.... 5.215 Raw data
.... 5.216 Read count
.... 5.217 Read length
.... 5.218 Read type
.... 5.219 Recipient patient reference
.... 5.220 Reference allele
.... 5.221 Reference genome FASTA path
.... 5.222 Reference Genome ID relationship
.... 5.223 Reference genome ID relationship
.... 5.224 Reference sequence
.... 5.225 Result of the instrumental investigation
.... 5.226 Rituximab pre-medication
.... 5.227 Sample ID
.... 5.228 Sample send to INGEMM date
.... 5.229 Sample type
.... 5.230 Scan date
.... 5.231 Second warm ischaemia time (minutes)
.... 5.232 Sentrix barcode array
.... 5.233 Sentrix position
.... 5.234 Sequence alteration
.... 5.235 Sequencing device
.... 5.236 SNP reader device
.... 5.237 Start date of maintenance therapy
.... 5.238 Start position
.... 5.239 Systolic blood pressure
.... 5.240 Target capture
.... 5.241 Target disease ID
.... 5.242 Target region ID
.... 5.243 Target region ID relationship
.... 5.244 Temperature
.... 5.245 Time from diagnosis to transplant (months)
.... 5.246 Transplant donor reference
.... 5.247 Transplant ID relationship
.... 5.248 Type of surgical biliary anastomosis
.... 5.249 Unit ID relationship
.... 5.250 Urine BKV-DNA
.... 5.251 Variant calling tools
.... 5.252 Variant class level
.... 5.253 Variant exon number
.... 5.254 Variant feature
.... 5.255 Variant occurrence ID relationship
.... 5.256 Variant origin
.... 5.257 Variant pathogenicity
.... 5.258 Variant read depth
.... 5.259 Variant tier level
.... 5.260 Vascular anomalies
.... 5.261 Vessel mismatch (donor-recipient)
.... 5.262 VZV serology IgG
.... 5.263 VZV serology IgM
.... 5.264 Weight
.... 5.265 ABO Group ValueSet
.... 5.266 BioSample Tissue Type ValueSet
.... 5.267 Concomitant Disease Category ValueSet
.... 5.268 Concomitant Medication Category ValueSet
.... 5.269 Dialysis method ValueSet
.... 5.270 Donor Liver Type ValueSet
.... 5.271 Donor type value set
.... 5.272 Immunosuppressant Drug Type
.... 5.273 Immunosuppressive Maintenance to Patient Type ValueSet
.... 5.274 Instrumental Investigation Name
.... 5.275 Intraoperative Complications ValueSet
.... 5.276 Kidney Side ValueSet
.... 5.277 Lab Result Unit ValueSet
.... 5.278 Lab Test Name
.... 5.279 Outcome Type Name
.... 5.280 Patient Instrumental Investigation Result ValueSet
.... 5.281 Post Event Type Name
.... 5.282 PRA Observation Type ValueSet
.... 5.283 Pre-medication Antihypertensive Drug ValueSet
.... 5.284 Pre-medication Type ValueSet
.... 5.285 Reference Genome Build ValueSet
.... 5.286 Rh Factor ValueSet
.... 5.287 Transplant Type ValueSet
.... 5.288 Type of surgical biliary anastomosis ValueSet
.... 5.289 Visit Type ValueSet
.... 5.290 ABO Group CodeSystem
.... 5.291 BioSample Tissue Type CodeSystem
.... 5.292 Concomitant Disease Category
.... 5.293 Concomitant Medication Category
.... 5.294 Donor Liver Type CodeSystem
.... 5.295 Donor type
.... 5.296 Immunosuppressant Drug Type
.... 5.297 Immunosuppressive Maintenance to Patient Type CodeSystem
.... 5.298 Instrumental Investigation Name
.... 5.299 Intraoperative Complications CodeSystem
.... 5.300 Kidney Side CodeSystem
.... 5.301 Lab Test Name
.... 5.302 Outcome Type Name
.... 5.303 Patient Instrumental Investigation Result CodeSystem
.... 5.304 Post Event Type Name
.... 5.305 PRA Observation Type CodeSystem
.... 5.306 Pre-medication Antihypertensive Drug CodeSystem
.... 5.307 Pre-medication Type CodeSystem
.... 5.308 Reference Genome Build CodeSystem
.... 5.309 Rh Factor CodeSystem
.... 5.310 Transplant Type CodeSystem
.... 5.311 Type of surgical biliary anastomosis CodeSystem
.... 5.312 Visit Type CodeSystem
.... 5.313 Example Biological Sample
.... 5.314 Example Clinical Variables
.... 5.315 Example Concomitant Disease
.... 5.316 Example Concomitant Episode
.... 5.317 Example Concomitant Medication
.... 5.318 Example donor ABO observation
.... 5.319 Example donor HLA class I typing
.... 5.320 Example donor HLA class II typing
.... 5.321 Example donor liver graft type
.... 5.322 Example donor observations list
.... 5.323 Example donor PRA observation
.... 5.324 Example donor pre-KTX dialysis type
.... 5.325 Example donor Rh observation
.... 5.326 Example Epigenome Study
.... 5.327 Example Genomic Test
.... 5.328 Example histological diagnosis date
.... 5.329 Example Immunosuppressant
.... 5.330 Example Immunosuppressant Induction to Patient
.... 5.331 Example Immunosuppressive Maintenance to Patient
.... 5.332 Example Instrumental Investigation
.... 5.333 Example Lab Result Observation
.... 5.334 Example Lab Test
.... 5.335 Example Laboratory Report
.... 5.336 Example liver disease diagnosis
.... 5.337 Example Marker of Immune Function
.... 5.338 Example Methylomic Study
.... 5.339 Example Microbiology record
.... 5.340 Example Outcome
.... 5.341 Example Outcome Type
.... 5.342 Example patient ABO observation
.... 5.343 Example patient HLA class I typing
.... 5.344 Example patient HLA class II typing
.... 5.345 Example Patient Instrumental Investigation
.... 5.346 Example patient last PRA observation
.... 5.347 Example patient max PRA observation
.... 5.348 Example patient observations list
.... 5.349 Example patient Rh observation
.... 5.350 Example Post Event Type
.... 5.351 Example Post-Transplant Event
.... 5.352 Example Pre-medication
.... 5.353 Example Reference Genome GRCh38
.... 5.354 Example renal disease diagnosis
.... 5.355 Example Target Region
.... 5.356 Example transplant
.... 5.357 Example transplant donor
.... 5.358 Example transplant recipient
.... 5.359 Example Variant Annotation
.... 5.360 Example Variant Occurrence
.... 5.361 Example visit