PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions
| Draft as of 2026-09-28 |
<ConceptMap xmlns="http://hl7.org/fhir">
<id value="dm-immunological-data-to-fhir"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: ConceptMap dm-immunological-data-to-fhir</b></p><a name="dm-immunological-data-to-fhir"> </a><a name="hcdm-immunological-data-to-fhir"> </a><p>Mapping from <a href="ValueSet-dm-immunological-data-variable-vs.html">PROTECT-CHILD DM immunological_data variables</a> to (not specified)</p><br/><p><b>Group 1 </b>Mapping from <a href="CodeSystem-dm-variable-cs.html">PROTECT-CHILD Data Model Variables</a> to <a href="http://terminology.hl7.org/6.3.0/CodeSystem-v3-loinc.html">Logical Observation Identifiers, Names and Codes (LOINC)</a></p><table class="grid"><tr><td><b>Source Code</b></td><td><b>Relationship</b></td><td><b>Target Code</b></td><td><b>Comment</b></td></tr><tr><td>immunological_data.blood_group</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent" title="equivalent">is equivalent to</a></td><td>883-9 (ABO group [Type] in Blood)</td><td>BloodGroupObservation.code</td></tr><tr><td>immunological_data.rh_factor</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent" title="equivalent">is equivalent to</a></td><td>10331-7 (Rh [Type] in Blood)</td><td>BloodGroupObservation.code</td></tr><tr><td>immunological_data.hla_a_1</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>13298-5 (HLA-A [Type])</td><td>HlaTyping.code. One Observation per allele: hla_a_1 and hla_a_2 become two HlaTyping resources with the same code, since HLA alleles are not ordered. Use 57290-9 or 78014-8 where the typing resolution is known.</td></tr><tr><td>immunological_data.hla_a_2</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>13298-5 (HLA-A [Type])</td><td>HlaTyping.code. See hla_a_1.</td></tr><tr><td>immunological_data.hla_b_1</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>13299-3 (HLA-B [Type])</td><td>HlaTyping.code. Use 57291-7 or 78015-5 where the resolution is known.</td></tr><tr><td>immunological_data.hla_b_2</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>13299-3 (HLA-B [Type])</td><td>HlaTyping.code. See hla_b_1.</td></tr><tr><td>immunological_data.hla_c_1</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>13302-5 (HLA-C [Type])</td><td>HlaTyping.code. Use 77636-9 or 96636-6 where the resolution is known.</td></tr><tr><td>immunological_data.hla_c_2</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>13302-5 (HLA-C [Type])</td><td>HlaTyping.code. See hla_c_1.</td></tr><tr><td>immunological_data.hla_drb1_1</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>57298-2 (HLA-DRB1 [Type])</td><td>HlaTyping.code. Use 57293-3 or 96664-8 where the resolution is known.</td></tr><tr><td>immunological_data.hla_drb1_2</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>57298-2 (HLA-DRB1 [Type])</td><td>HlaTyping.code. See hla_drb1_1.</td></tr><tr><td>immunological_data.hla_dp_1</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>12285-3 (HLA-DP [Type])</td><td>HlaTyping.code. The DM values are DPB1 alleles at an unrecorded resolution, so the ambiguous DP code is the safe migration target; new data SHOULD use 59017-4 (DPB1 high resolution) or 96648-1 (low resolution).</td></tr><tr><td>immunological_data.hla_dp_2</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>12285-3 (HLA-DP [Type])</td><td>HlaTyping.code. See hla_dp_1.</td></tr><tr><td>immunological_data.hla_dqb1_1</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>53938-7 (HLA-DQB1 [Type])</td><td>HlaTyping.code. Use 57299-0 or 78017-1 where the resolution is known.</td></tr><tr><td>immunological_data.hla_dqb1_2</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-wider" title="wider">maps to wider concept</a></td><td>53938-7 (HLA-DQB1 [Type])</td><td>HlaTyping.code. See hla_dqb1_1.</td></tr><tr><td>immunological_data.anti_hla_antibodies</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent" title="equivalent">is equivalent to</a></td><td>44534-6 (HLA Ab [Presence] in Serum)</td><td>AntiHlaAntibodyScreen.code. The DM boolean becomes a Positive or Negative result, so a negative screen is recorded rather than inferred from absence.</td></tr><tr><td>immunological_data.pre_transplant_anti_hla_dsa</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-narrower" title="narrower">narrower</a></td><td>107913-6 (HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Presence] in Serum or Plasma)</td><td>AntiHlaAntibodyScreen.code, with the DM free text in AntiHlaAntibodyScreen.note.</td></tr><tr><td>immunological_data.antibody_type</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-narrower" title="narrower">narrower</a></td><td>107914-4 (HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Identifier] in Serum or Plasma)</td><td>AntiHlaAntibody.code; the target HLA specificity becomes AntiHlaAntibody.valueString, one Observation per antibody. Use 98006-0 for an antibody that is not donor-specific.</td></tr><tr><td>immunological_data.ihc_if_c4d</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent" title="equivalent">is equivalent to</a></td><td>49461-7 (C4d Ag [Presence] in Tissue by Immune stain)</td><td>C4dStain.code. The DM boolean maps to BanffC4dScoreCS c4d-0 (false) or c4d-1..c4d-3 (true).</td></tr><tr><td>immunological_data.anca</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent" title="equivalent">is equivalent to</a></td><td>17351-8 (Neutrophil cytoplasmic Ab [Presence] in Serum)</td><td>AncaObservation.code. The DM boolean becomes Positive or Negative.</td></tr></table><hr/><p><b>Group 2 </b>Mapping from <a href="CodeSystem-dm-variable-cs.html">PROTECT-CHILD Data Model Variables</a> to <a href="CodeSystem-imm-data-component-cs.html">Immunological Data Component Codes</a></p><table class="grid"><tr><td><b>Source Code</b></td><td><b>Relationship</b></td><td><b>Target Code</b></td><td><b>Comment</b></td></tr><tr><td>immunological_data.post_transplant_ab_anti_hla_dsa_class</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent" title="equivalent">is equivalent to</a></td><td>hla-class (HLA class of the antibody)</td><td>AntiHlaAntibody.component[hla_class].code. LOINC has no component code for antibody class.</td></tr><tr><td>immunological_data.mfi</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent" title="equivalent">is equivalent to</a></td><td>mfi-category (MFI band)</td><td>AntiHlaAntibody.component[mfi_category].code. The measured MFI, where the laboratory reports it, goes in component[mfi_value].</td></tr></table><hr/><p><b>Group 3 </b>Mapping from <a href="CodeSystem-dm-variable-cs.html">PROTECT-CHILD Data Model Variables</a> to <a href="CodeSystem-graft-pathology-cs.html">Graft Pathology Codes</a></p><table class="grid"><tr><td><b>Source Code</b></td><td><b>Relationship</b></td><td><b>Target Code</b></td><td><b>Comment</b></td></tr><tr><td>immunological_data.banff_category</td><td><a href="http://hl7.org/fhir/R4/codesystem-concept-map-equivalence.html#concept-map-equivalence-equivalent" title="equivalent">is equivalent to</a></td><td>banff-category (Banff diagnostic category)</td><td>BanffAssessment.code, on the GraftBiopsy built from the same DM row. Neither LOINC nor SNOMED CT carries the Banff classification.</td></tr></table></div>
</text>
<url
value="https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/ConceptMap/dm-immunological-data-to-fhir"/>
<version value="0.1.0-ci-build"/>
<name value="DmImmunologicalDataToFhir"/>
<title value="DM immunological_data columns → FHIR codes"/>
<status value="draft"/>
<experimental value="true"/>
<date value="2026-09-28T06:51:47+00:00"/>
<publisher value="Protect Child"/>
<contact>
<name value="Protect Child"/>
<telecom>
<system value="url"/>
<value value="https://protect-child.eu/"/>
</telecom>
</contact>
<description
value="Maps each result column of the DMv1.2 immunological_data table to the code of the resource it becomes. The row itself becomes an ImmunologicalDataReport, and the biopsy columns a GraftBiopsy carrying the same immunological_data_id. Three columns have no code of their own: `if` becomes GraftBiopsy.conclusion, `c4d` becomes C4dStain.note, and the free text of `pre_transplant_anti_hla_dsa` becomes AntiHlaAntibodyScreen.note. The HLA columns are marked `wider` because each maps to a locus code shared by both allele columns: one Observation per allele replaces the ordered pair of slots."/>
<sourceCanonical
value="https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/ValueSet/dm-immunological-data-variable-vs"/>
<group>
<source
value="https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs"/>
<target value="http://loinc.org"/>
<element>
<code value="immunological_data.blood_group"/>
<target>
<code value="883-9"/>
<display value="ABO group [Type] in Blood"/>
<equivalence value="equivalent"/>
<comment value="BloodGroupObservation.code"/>
</target>
</element>
<element>
<code value="immunological_data.rh_factor"/>
<target>
<code value="10331-7"/>
<display value="Rh [Type] in Blood"/>
<equivalence value="equivalent"/>
<comment value="BloodGroupObservation.code"/>
</target>
</element>
<element>
<code value="immunological_data.hla_a_1"/>
<target>
<code value="13298-5"/>
<display value="HLA-A [Type]"/>
<equivalence value="wider"/>
<comment
value="HlaTyping.code. One Observation per allele: hla_a_1 and hla_a_2 become two HlaTyping resources with the same code, since HLA alleles are not ordered. Use 57290-9 or 78014-8 where the typing resolution is known."/>
</target>
</element>
<element>
<code value="immunological_data.hla_a_2"/>
<target>
<code value="13298-5"/>
<display value="HLA-A [Type]"/>
<equivalence value="wider"/>
<comment value="HlaTyping.code. See hla_a_1."/>
</target>
</element>
<element>
<code value="immunological_data.hla_b_1"/>
<target>
<code value="13299-3"/>
<display value="HLA-B [Type]"/>
<equivalence value="wider"/>
<comment
value="HlaTyping.code. Use 57291-7 or 78015-5 where the resolution is known."/>
</target>
</element>
<element>
<code value="immunological_data.hla_b_2"/>
<target>
<code value="13299-3"/>
<display value="HLA-B [Type]"/>
<equivalence value="wider"/>
<comment value="HlaTyping.code. See hla_b_1."/>
</target>
</element>
<element>
<code value="immunological_data.hla_c_1"/>
<target>
<code value="13302-5"/>
<display value="HLA-C [Type]"/>
<equivalence value="wider"/>
<comment
value="HlaTyping.code. Use 77636-9 or 96636-6 where the resolution is known."/>
</target>
</element>
<element>
<code value="immunological_data.hla_c_2"/>
<target>
<code value="13302-5"/>
<display value="HLA-C [Type]"/>
<equivalence value="wider"/>
<comment value="HlaTyping.code. See hla_c_1."/>
</target>
</element>
<element>
<code value="immunological_data.hla_drb1_1"/>
<target>
<code value="57298-2"/>
<display value="HLA-DRB1 [Type]"/>
<equivalence value="wider"/>
<comment
value="HlaTyping.code. Use 57293-3 or 96664-8 where the resolution is known."/>
</target>
</element>
<element>
<code value="immunological_data.hla_drb1_2"/>
<target>
<code value="57298-2"/>
<display value="HLA-DRB1 [Type]"/>
<equivalence value="wider"/>
<comment value="HlaTyping.code. See hla_drb1_1."/>
</target>
</element>
<element>
<code value="immunological_data.hla_dp_1"/>
<target>
<code value="12285-3"/>
<display value="HLA-DP [Type]"/>
<equivalence value="wider"/>
<comment
value="HlaTyping.code. The DM values are DPB1 alleles at an unrecorded resolution, so the ambiguous DP code is the safe migration target; new data SHOULD use 59017-4 (DPB1 high resolution) or 96648-1 (low resolution)."/>
</target>
</element>
<element>
<code value="immunological_data.hla_dp_2"/>
<target>
<code value="12285-3"/>
<display value="HLA-DP [Type]"/>
<equivalence value="wider"/>
<comment value="HlaTyping.code. See hla_dp_1."/>
</target>
</element>
<element>
<code value="immunological_data.hla_dqb1_1"/>
<target>
<code value="53938-7"/>
<display value="HLA-DQB1 [Type]"/>
<equivalence value="wider"/>
<comment
value="HlaTyping.code. Use 57299-0 or 78017-1 where the resolution is known."/>
</target>
</element>
<element>
<code value="immunological_data.hla_dqb1_2"/>
<target>
<code value="53938-7"/>
<display value="HLA-DQB1 [Type]"/>
<equivalence value="wider"/>
<comment value="HlaTyping.code. See hla_dqb1_1."/>
</target>
</element>
<element>
<code value="immunological_data.anti_hla_antibodies"/>
<target>
<code value="44534-6"/>
<display value="HLA Ab [Presence] in Serum"/>
<equivalence value="equivalent"/>
<comment
value="AntiHlaAntibodyScreen.code. The DM boolean becomes a Positive or Negative result, so a negative screen is recorded rather than inferred from absence."/>
</target>
</element>
<element>
<code value="immunological_data.pre_transplant_anti_hla_dsa"/>
<target>
<code value="107913-6"/>
<display
value="HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Presence] in Serum or Plasma"/>
<equivalence value="narrower"/>
<comment
value="AntiHlaAntibodyScreen.code, with the DM free text in AntiHlaAntibodyScreen.note."/>
</target>
</element>
<element>
<code value="immunological_data.antibody_type"/>
<target>
<code value="107914-4"/>
<display
value="HLA-A and B and C (class I) and HLA-DP and DQ and DR (class II) Ab.IgG donor specific [Identifier] in Serum or Plasma"/>
<equivalence value="narrower"/>
<comment
value="AntiHlaAntibody.code; the target HLA specificity becomes AntiHlaAntibody.valueString, one Observation per antibody. Use 98006-0 for an antibody that is not donor-specific."/>
</target>
</element>
<element>
<code value="immunological_data.ihc_if_c4d"/>
<target>
<code value="49461-7"/>
<display value="C4d Ag [Presence] in Tissue by Immune stain"/>
<equivalence value="equivalent"/>
<comment
value="C4dStain.code. The DM boolean maps to BanffC4dScoreCS c4d-0 (false) or c4d-1..c4d-3 (true)."/>
</target>
</element>
<element>
<code value="immunological_data.anca"/>
<target>
<code value="17351-8"/>
<display value="Neutrophil cytoplasmic Ab [Presence] in Serum"/>
<equivalence value="equivalent"/>
<comment
value="AncaObservation.code. The DM boolean becomes Positive or Negative."/>
</target>
</element>
</group>
<group>
<source
value="https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs"/>
<target
value="https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs"/>
<element>
<code value="immunological_data.post_transplant_ab_anti_hla_dsa_class"/>
<target>
<code value="hla-class"/>
<display value="HLA class of the antibody"/>
<equivalence value="equivalent"/>
<comment
value="AntiHlaAntibody.component[hla_class].code. LOINC has no component code for antibody class."/>
</target>
</element>
<element>
<code value="immunological_data.mfi"/>
<target>
<code value="mfi-category"/>
<display value="MFI band"/>
<equivalence value="equivalent"/>
<comment
value="AntiHlaAntibody.component[mfi_category].code. The measured MFI, where the laboratory reports it, goes in component[mfi_value]."/>
</target>
</element>
</group>
<group>
<source
value="https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/dm-variable-cs"/>
<target
value="https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/graft-pathology-cs"/>
<element>
<code value="immunological_data.banff_category"/>
<target>
<code value="banff-category"/>
<display value="Banff diagnostic category"/>
<equivalence value="equivalent"/>
<comment
value="BanffAssessment.code, on the GraftBiopsy built from the same DM row. Neither LOINC nor SNOMED CT carries the Banff classification."/>
</target>
</element>
</group>
</ConceptMap>