PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build -
PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build
PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build
PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions
| Draft as of 2026-09-28 |
<ValueSet xmlns="http://hl7.org/fhir">
<id value="clinical-event-type-vs"/>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: ValueSet clinical-event-type-vs</b></p><a name="clinical-event-type-vs"> </a><a name="hcclinical-event-type-vs"> </a><p>This value set includes codes based on the following rules:</p><ul><li>Include these codes as defined in <a href="http://www.snomed.org/"><code>http://snomed.info/sct</code></a><span title="Version is not explicitly stated. No matching Code System found"> version Not Stated (use latest from terminology server)</span><table class="none"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td></tr><tr><td><a href="http://snomed.info/id/118926004">118926004</a></td><td>Disorder of bile duct</td></tr><tr><td><a href="http://snomed.info/id/713886006">713886006</a></td><td>BK virus nephropathy</td></tr><tr><td><a href="http://snomed.info/id/235886005">235886005</a></td><td>Chronic hepatic failure</td></tr><tr><td><a href="http://snomed.info/id/432908002">432908002</a></td><td>Chronic rejection of liver transplant</td></tr><tr><td><a href="http://snomed.info/id/90688005">90688005</a></td><td>Chronic renal failure</td></tr><tr><td><a href="http://snomed.info/id/28944009">28944009</a></td><td>Cytomegalovirus infection</td></tr><tr><td><a href="http://snomed.info/id/426136000">426136000</a></td><td>Delayed renal graft function</td></tr><tr><td><a href="http://snomed.info/id/73211009">73211009</a></td><td>Diabetes mellitus</td></tr><tr><td><a href="http://snomed.info/id/269295009">269295009</a></td><td>Transplanted organ failure</td></tr><tr><td><a href="http://snomed.info/id/38341003">38341003</a></td><td>Hypertensive disorder</td></tr><tr><td><a href="http://snomed.info/id/236569000">236569000</a></td><td>Primary non-function of renal transplant</td></tr><tr><td><a href="http://snomed.info/id/236570004">236570004</a></td><td>Renal transplant rejection</td></tr><tr><td><a href="http://snomed.info/id/235911006">235911006</a></td><td>Liver transplant rejection</td></tr><tr><td><a href="http://snomed.info/id/126729006">126729006</a></td><td>Thrombotic microangiopathy</td></tr><tr><td><a href="http://snomed.info/id/419620001">419620001</a></td><td>Death</td></tr><tr><td><a href="http://snomed.info/id/450886002">450886002</a></td><td>Posterior reversible encephalopathy syndrome</td></tr><tr><td><a href="http://snomed.info/id/254290004">254290004</a></td><td>Lymphoproliferative disorder following transplantation</td></tr><tr><td><a href="http://snomed.info/id/363339009">363339009</a></td><td>Urological system complication of procedure</td></tr><tr><td><a href="http://snomed.info/id/28104001">28104001</a></td><td>Vascular complication of medical care</td></tr><tr><td><a href="http://snomed.info/id/14669001">14669001</a></td><td>Acute kidney injury</td></tr></table></li><li>Include these codes as defined in <a href="CodeSystem-clinical-event-type-cs.html"><code>https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/clinical-event-type-cs</code></a><span title="Version is not explicitly stated, which means it is fixed to the version provided in this specification"> version 📦0.1.0-ci-build</span><table class="none"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td><a href="CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-alloimmunization">alloimmunization</a></td><td style="color: #cccccc">Alloimmunization</td><td>Development of antibodies against alloantigens (e.g. HLA) following transplantation or transfusion.</td></tr><tr><td><a href="CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-liver-early-allograft-dysfunction">liver-early-allograft-dysfunction</a></td><td style="color: #cccccc">Liver Early Allograft Dysfunction</td><td>Early dysfunction of the liver allograft in the initial post-transplant period.</td></tr><tr><td><a href="CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-liver-primary-non-function">liver-primary-non-function</a></td><td style="color: #cccccc">Liver Primary Non-Function</td><td>Liver allograft that never achieves function after transplantation, leading to urgent retransplantation or death.</td></tr><tr><td><a href="CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-mtor-inhibitors-toxicity">mtor-inhibitors-toxicity</a></td><td style="color: #cccccc">mTOR Inhibitors Toxicity</td><td>Adverse effects attributable to mTOR-inhibitor immunosuppression.</td></tr><tr><td><a href="CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-mycophenolate-toxicity">mycophenolate-toxicity</a></td><td style="color: #cccccc">Mycophenolate Toxicity</td><td>Adverse effects attributable to mycophenolate immunosuppression.</td></tr><tr><td><a href="CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-relapse-primary-immunomediated-disease">relapse-primary-immunomediated-disease</a></td><td style="color: #cccccc">Relapse Primary Immunomediated Disease</td><td>Recurrence of the primary immune-mediated disease that led to transplantation.</td></tr><tr><td><a href="CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-renal-cni-toxicity">renal-cni-toxicity</a></td><td style="color: #cccccc">Renal CNI Toxicity</td><td>Calcineurin-inhibitor-induced renal toxicity.</td></tr><tr><td><a href="CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-histologic-evidence-cni-toxicity">histologic-evidence-cni-toxicity</a></td><td style="color: #cccccc">Histological evidence of CNI nephrotoxicity</td><td>Histological findings consistent with calcineurin-inhibitor nephrotoxicity.</td></tr><tr><td><a href="CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-hypoxic-ischemic-event-pltx">hypoxic-ischemic-event-pltx</a></td><td style="color: #cccccc">Hypoxic-ischemic event post liver transplant</td><td>Hypoxic-ischemic event occurring after paediatric liver transplantation (Liver/combined).</td></tr></table></li></ul></div>
</text>
<url
value="https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/ValueSet/clinical-event-type-vs"/>
<version value="0.1.0-ci-build"/>
<name value="ClinicalEventTypeVS"/>
<title value="Clinical Event Type ValueSet"/>
<status value="draft"/>
<experimental value="true"/>
<date value="2026-09-28T06:51:47+00:00"/>
<publisher value="Protect Child"/>
<contact>
<name value="Protect Child"/>
<telecom>
<system value="url"/>
<value value="https://protect-child.eu/"/>
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<description
value="Allowed clinical event types in the PROTECT-CHILD study (DMv1.2)."/>
<compose>
<include>
<system value="http://snomed.info/sct"/>
<concept>
<code value="118926004"/>
<display value="Disorder of bile duct"/>
</concept>
<concept>
<code value="713886006"/>
<display value="BK virus nephropathy"/>
</concept>
<concept>
<code value="235886005"/>
<display value="Chronic hepatic failure"/>
</concept>
<concept>
<code value="432908002"/>
<display value="Chronic rejection of liver transplant"/>
</concept>
<concept>
<code value="90688005"/>
<display value="Chronic renal failure"/>
</concept>
<concept>
<code value="28944009"/>
<display value="Cytomegalovirus infection"/>
</concept>
<concept>
<code value="426136000"/>
<display value="Delayed renal graft function"/>
</concept>
<concept>
<code value="73211009"/>
<display value="Diabetes mellitus"/>
</concept>
<concept>
<code value="269295009"/>
<display value="Transplanted organ failure"/>
</concept>
<concept>
<code value="38341003"/>
<display value="Hypertensive disorder"/>
</concept>
<concept>
<code value="236569000"/>
<display value="Primary non-function of renal transplant"/>
</concept>
<concept>
<code value="236570004"/>
<display value="Renal transplant rejection"/>
</concept>
<concept>
<code value="235911006"/>
<display value="Liver transplant rejection"/>
</concept>
<concept>
<code value="126729006"/>
<display value="Thrombotic microangiopathy"/>
</concept>
<concept>
<code value="419620001"/>
<display value="Death"/>
</concept>
<concept>
<code value="450886002"/>
<display value="Posterior reversible encephalopathy syndrome"/>
</concept>
<concept>
<code value="254290004"/>
<display
value="Lymphoproliferative disorder following transplantation"/>
</concept>
<concept>
<code value="363339009"/>
<display value="Urological system complication of procedure"/>
</concept>
<concept>
<code value="28104001"/>
<display value="Vascular complication of medical care"/>
</concept>
<concept>
<code value="14669001"/>
<display value="Acute kidney injury"/>
</concept>
</include>
<include>
<system
value="https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/clinical-event-type-cs"/>
<concept>
<code value="alloimmunization"/>
</concept>
<concept>
<code value="liver-early-allograft-dysfunction"/>
</concept>
<concept>
<code value="liver-primary-non-function"/>
</concept>
<concept>
<code value="mtor-inhibitors-toxicity"/>
</concept>
<concept>
<code value="mycophenolate-toxicity"/>
</concept>
<concept>
<code value="relapse-primary-immunomediated-disease"/>
</concept>
<concept>
<code value="renal-cni-toxicity"/>
</concept>
<concept>
<code value="histologic-evidence-cni-toxicity"/>
</concept>
<concept>
<code value="hypoxic-ischemic-event-pltx"/>
</concept>
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