PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build -
PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build
PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build
PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions
| Draft as of 2026-09-28 |
{
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"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ValueSet clinical-event-type-vs</b></p><a name=\"clinical-event-type-vs\"> </a><a name=\"hcclinical-event-type-vs\"> </a><p>This value set includes codes based on the following rules:</p><ul><li>Include these codes as defined in <a href=\"http://www.snomed.org/\"><code>http://snomed.info/sct</code></a><span title=\"Version is not explicitly stated. No matching Code System found\"> version Not Stated (use latest from terminology server)</span><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td><a href=\"http://snomed.info/id/118926004\">118926004</a></td><td>Disorder of bile duct</td></tr><tr><td><a href=\"http://snomed.info/id/713886006\">713886006</a></td><td>BK virus nephropathy</td></tr><tr><td><a href=\"http://snomed.info/id/235886005\">235886005</a></td><td>Chronic hepatic failure</td></tr><tr><td><a href=\"http://snomed.info/id/432908002\">432908002</a></td><td>Chronic rejection of liver transplant</td></tr><tr><td><a href=\"http://snomed.info/id/90688005\">90688005</a></td><td>Chronic renal failure</td></tr><tr><td><a href=\"http://snomed.info/id/28944009\">28944009</a></td><td>Cytomegalovirus infection</td></tr><tr><td><a href=\"http://snomed.info/id/426136000\">426136000</a></td><td>Delayed renal graft function</td></tr><tr><td><a href=\"http://snomed.info/id/73211009\">73211009</a></td><td>Diabetes mellitus</td></tr><tr><td><a href=\"http://snomed.info/id/269295009\">269295009</a></td><td>Transplanted organ failure</td></tr><tr><td><a href=\"http://snomed.info/id/38341003\">38341003</a></td><td>Hypertensive disorder</td></tr><tr><td><a href=\"http://snomed.info/id/236569000\">236569000</a></td><td>Primary non-function of renal transplant</td></tr><tr><td><a href=\"http://snomed.info/id/236570004\">236570004</a></td><td>Renal transplant rejection</td></tr><tr><td><a href=\"http://snomed.info/id/235911006\">235911006</a></td><td>Liver transplant rejection</td></tr><tr><td><a href=\"http://snomed.info/id/126729006\">126729006</a></td><td>Thrombotic microangiopathy</td></tr><tr><td><a href=\"http://snomed.info/id/419620001\">419620001</a></td><td>Death</td></tr><tr><td><a href=\"http://snomed.info/id/450886002\">450886002</a></td><td>Posterior reversible encephalopathy syndrome</td></tr><tr><td><a href=\"http://snomed.info/id/254290004\">254290004</a></td><td>Lymphoproliferative disorder following transplantation</td></tr><tr><td><a href=\"http://snomed.info/id/363339009\">363339009</a></td><td>Urological system complication of procedure</td></tr><tr><td><a href=\"http://snomed.info/id/28104001\">28104001</a></td><td>Vascular complication of medical care</td></tr><tr><td><a href=\"http://snomed.info/id/14669001\">14669001</a></td><td>Acute kidney injury</td></tr></table></li><li>Include these codes as defined in <a href=\"CodeSystem-clinical-event-type-cs.html\"><code>https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/clinical-event-type-cs</code></a><span title=\"Version is not explicitly stated, which means it is fixed to the version provided in this specification\"> version 📦0.1.0-ci-build</span><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td><a href=\"CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-alloimmunization\">alloimmunization</a></td><td style=\"color: #cccccc\">Alloimmunization</td><td>Development of antibodies against alloantigens (e.g. HLA) following transplantation or transfusion.</td></tr><tr><td><a href=\"CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-liver-early-allograft-dysfunction\">liver-early-allograft-dysfunction</a></td><td style=\"color: #cccccc\">Liver Early Allograft Dysfunction</td><td>Early dysfunction of the liver allograft in the initial post-transplant period.</td></tr><tr><td><a href=\"CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-liver-primary-non-function\">liver-primary-non-function</a></td><td style=\"color: #cccccc\">Liver Primary Non-Function</td><td>Liver allograft that never achieves function after transplantation, leading to urgent retransplantation or death.</td></tr><tr><td><a href=\"CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-mtor-inhibitors-toxicity\">mtor-inhibitors-toxicity</a></td><td style=\"color: #cccccc\">mTOR Inhibitors Toxicity</td><td>Adverse effects attributable to mTOR-inhibitor immunosuppression.</td></tr><tr><td><a href=\"CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-mycophenolate-toxicity\">mycophenolate-toxicity</a></td><td style=\"color: #cccccc\">Mycophenolate Toxicity</td><td>Adverse effects attributable to mycophenolate immunosuppression.</td></tr><tr><td><a href=\"CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-relapse-primary-immunomediated-disease\">relapse-primary-immunomediated-disease</a></td><td style=\"color: #cccccc\">Relapse Primary Immunomediated Disease</td><td>Recurrence of the primary immune-mediated disease that led to transplantation.</td></tr><tr><td><a href=\"CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-renal-cni-toxicity\">renal-cni-toxicity</a></td><td style=\"color: #cccccc\">Renal CNI Toxicity</td><td>Calcineurin-inhibitor-induced renal toxicity.</td></tr><tr><td><a href=\"CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-histologic-evidence-cni-toxicity\">histologic-evidence-cni-toxicity</a></td><td style=\"color: #cccccc\">Histological evidence of CNI nephrotoxicity</td><td>Histological findings consistent with calcineurin-inhibitor nephrotoxicity.</td></tr><tr><td><a href=\"CodeSystem-clinical-event-type-cs.html#clinical-event-type-cs-hypoxic-ischemic-event-pltx\">hypoxic-ischemic-event-pltx</a></td><td style=\"color: #cccccc\">Hypoxic-ischemic event post liver transplant</td><td>Hypoxic-ischemic event occurring after paediatric liver transplantation (Liver/combined).</td></tr></table></li></ul></div>"
},
"url" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/ValueSet/clinical-event-type-vs",
"version" : "0.1.0-ci-build",
"name" : "ClinicalEventTypeVS",
"title" : "Clinical Event Type ValueSet",
"status" : "draft",
"experimental" : true,
"date" : "2026-09-28T06:51:47+00:00",
"publisher" : "Protect Child",
"contact" : [
{
"name" : "Protect Child",
"telecom" : [
{
"system" : "url",
"value" : "https://protect-child.eu/"
}
]
}
],
"description" : "Allowed clinical event types in the PROTECT-CHILD study (DMv1.2).",
"compose" : {
"include" : [
{
"system" : "http://snomed.info/sct",
"concept" : [
{
"code" : "118926004",
"display" : "Disorder of bile duct"
},
{
"code" : "713886006",
"display" : "BK virus nephropathy"
},
{
"code" : "235886005",
"display" : "Chronic hepatic failure"
},
{
"code" : "432908002",
"display" : "Chronic rejection of liver transplant"
},
{
"code" : "90688005",
"display" : "Chronic renal failure"
},
{
"code" : "28944009",
"display" : "Cytomegalovirus infection"
},
{
"code" : "426136000",
"display" : "Delayed renal graft function"
},
{
"code" : "73211009",
"display" : "Diabetes mellitus"
},
{
"code" : "269295009",
"display" : "Transplanted organ failure"
},
{
"code" : "38341003",
"display" : "Hypertensive disorder"
},
{
"code" : "236569000",
"display" : "Primary non-function of renal transplant"
},
{
"code" : "236570004",
"display" : "Renal transplant rejection"
},
{
"code" : "235911006",
"display" : "Liver transplant rejection"
},
{
"code" : "126729006",
"display" : "Thrombotic microangiopathy"
},
{
"code" : "419620001",
"display" : "Death"
},
{
"code" : "450886002",
"display" : "Posterior reversible encephalopathy syndrome"
},
{
"code" : "254290004",
"display" : "Lymphoproliferative disorder following transplantation"
},
{
"code" : "363339009",
"display" : "Urological system complication of procedure"
},
{
"code" : "28104001",
"display" : "Vascular complication of medical care"
},
{
"code" : "14669001",
"display" : "Acute kidney injury"
}
]
},
{
"system" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/clinical-event-type-cs",
"concept" : [
{
"code" : "alloimmunization"
},
{
"code" : "liver-early-allograft-dysfunction"
},
{
"code" : "liver-primary-non-function"
},
{
"code" : "mtor-inhibitors-toxicity"
},
{
"code" : "mycophenolate-toxicity"
},
{
"code" : "relapse-primary-immunomediated-disease"
},
{
"code" : "renal-cni-toxicity"
},
{
"code" : "histologic-evidence-cni-toxicity"
},
{
"code" : "hypoxic-ischemic-event-pltx"
}
]
}
]
}
}