PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build -
PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build
PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build
PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions
Bundle ProtectChildKidneyRecipientJourneyExample of type collection
Entry 1 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Organization/PCCenter2Padova
Resource Organization:
Profile: Study Centre
identifier: ProtectChildStudyCentreId/2
name: University of Padova
Contacts
Address IT
Entry 2 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Patient/KidneyRecipient1
Resource Patient:
Profile: Transplant Recipient
Anonymous Patient Male, DoB Unknown ( https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/protect-child-id#ProtectChildId#REC-2-0001)
Links:
- Managing Organization: Organization University of Padova
Entry 3 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Patient/KidneyDonor1
Resource Patient:
Profile: Transplant Donor
Anonymous Patient Female, DoB: 1988-04-11 ( https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/protect-child-id#ProtectChildId#DON-2-0001)
Deceased: false
Entry 4 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Medication/ImmunosuppressantBasiliximab1
Resource Medication:
Profile: Immunosuppressant
identifier: ProtectChildId/IMM-0003
code: Basiliximab
status: Active
Entry 5 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Medication/ImmunosuppressantTacrolimus1
Resource Medication:
Profile: Immunosuppressant
identifier: ProtectChildId/IMM-0002
code: CNI (FK506)
status: Active
Entry 6 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Medication/ImmunosuppressantExample1
Resource Medication:
Profile: Immunosuppressant
identifier: ProtectChildId/IMM-0001
code: Steroid (methylprednisolone)
status: Active
Entry 7 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Condition/KidneyRecipientDiagnosis1
Resource Condition:
Profile: Patient Primary Disease Diagnosis
clinicalStatus: Active
code: Chronic kidney disease, stage 5
bodySite: Kidney structure
onset: 2021-11-04
Entry 8 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Encounter/KidneyVisitPreTx1
Resource Encounter:
Profile: Visit
identifier: ProtectChildId/VIS-2-0001
status: completed
class: inpatient encounter
type: Pre-transplant visit
Entry 9 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/KidneyRecipientAge1
Resource Observation:
Profile: Patient Demographics Observation
status: Final
category: Survey
code: Patient demographics panel (age)
effective: 2024-03-12
performer: Organization University of Padova
component
code: Age
value: 12 years (Details: UCUM codea = 'a')
component
code: Patient age in months
value: 144 months (Details: UCUM codemo = 'mo')
Entry 10 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Procedure/KidneyTransplant1
Resource Procedure:
Profile: Transplant
Transplant donor reference: Anonymous Patient Female, DoB: 1988-04-11 ( https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/protect-child-id#ProtectChildId#DON-2-0001)
identifier: ProtectChildId/TXP-2-0001
status: Completed
code: Kidney transplant
complication: No display for Procedure.complication (reference: ->Condition Kidney ischemia)
Entry 11 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Procedure/KidneyAnastomosis1
Resource Procedure:
Profile: Transplant Anastomosis
partOf: Procedure Kidney transplant
status: Completed
code: Standard
Entry 12 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Condition/KidneyIntraopComplication1
Resource Condition:
Profile: Intraoperative Complication
clinicalStatus: Active
category: Encounter Diagnosis
code: Kidney ischemia
onset: 2024-03-12
Entry 13 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Condition/KidneyEventDgf1
Resource Condition:
Profile: Clinical Event
identifier: ProtectChildId/CLE-2-0001
clinicalStatus: Active
code: Delayed Kidney Graft Function
onset: 2024-03-15
Entry 14 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Procedure/KidneyDialysis1
Resource Procedure:
Profile: Clinical Event Procedure
status: Completed
code: Hemodialysis
Entry 15 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/MedicationStatement/KidneyImmPatInduction1
Resource MedicationStatement:
Profile: Immunosuppressant to Patient
status: completed
identifier: ProtectChildId/IMP-2-0002
status: recorded
category: Induction
effective: 2024-03-12 --> 2024-03-16
dosage
DoseAndRates
Dose[x] 20 mg (Details: UCUM codemg = 'mg')
Entry 16 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Encounter/KidneyVisitMonth1
Resource Encounter:
Profile: Visit
identifier: ProtectChildId/VIS-2-0002
status: completed
class: ambulatory
type: 1 month visit
Entry 17 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/KidneyVitalSign1
Resource Observation:
Profile: Vital Sign
identifier: ProtectChildId/VIT-2-0001
status: Final
category: Vital Signs
code: Vital signs panel
effective: 2024-04-12
performer: Organization University of Padova
component
code: Systolic blood pressure
value: 124 mmHg (Details: UCUM codemm[Hg] = 'mm[Hg]')
component
code: Diastolic blood pressure
value: 78 mmHg (Details: UCUM codemm[Hg] = 'mm[Hg]')
component
code: Systolic blood pressure percentile
value: 95
component
code: Diastolic blood pressure percentile
value: 88
Entry 18 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/kidney-lab-creatinine-month-1
Resource Observation:
Profile: Lab Result
identifier: ProtectChildId/LBR-2-0001
status: Final
category: Laboratory
code: Creatinine [Mass/volume] in Serum or Plasma
effective: 2024-04-12 08:40:00+0200
performer: Organization University of Padova
value: 1.6 mg/dL (Details: UCUM codemg/dL = 'mg/dL')
interpretation: High
Entry 19 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/KidneyInvestigation1
Resource Observation:
Profile: Patient Instrumental Investigation
identifier: ProtectChildId/IIV-2-0001
status: Final
code: Kidney doppler ultrasound
effective: 2024-04-12
performer: Organization University of Padova
value: Normal
Entry 20 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/MedicationStatement/KidneyImmPatMaintenance1
Resource MedicationStatement:
Profile: Immunosuppressant to Patient
status: active
identifier: ProtectChildId/IMP-2-0001
status: recorded
category: Maintenance
effective: 2024-03-12 --> 2024-06-20
dosage
text: Divided twice daily.
DoseAndRates
Dose[x] 0.1 mg/kg (Details: UCUM codemg.kg-1 = 'mg.kg-1')
Entry 21 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/KidneyImmPatPk1
Resource Observation:
Profile: Immunosuppressant PK Observation
status: Final
category: Laboratory
code: Pre-dose drug level (trough / C0)
effective: 2024-04-12
performer: Organization University of Padova
value: 6.2 ng/mL (Details: UCUM codeng.mL-1 = 'ng.mL-1')
Entry 22 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Encounter/KidneyVisitRejection1
Resource Encounter:
Profile: Visit
identifier: ProtectChildId/VIS-2-0003
status: completed
class: ambulatory
type: Clinical Event visit
Entry 23 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/KidneyMicrobiology1
Resource Observation:
Profile: Microbiology
Transplant type context: Kidney transplant
identifier: ProtectChildId/MIC-2-0001
status: Final
code: Microbiology studies panel
effective: 2024-06-20
performer: Organization University of Padova
component
code: Blood BKV-DNA
value: true
component
code: Blood BKV-DNA copies/ml
value: 42000 copies/mL (Details: UCUM code{copies}/mL = '{copies}/mL')
component
code: Urine BKV-DNA
value: true
component
code: BKV-DNA on kidney biopsy
value: true
component
code: BKV FISH on kidney biopsy
value: true
Entry 24 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Condition/KidneyMicrobiologyDiagnosis1
Resource Condition:
Profile: Microbiology Diagnosis
category: Encounter Diagnosis
code: Histological evidence of BKVAN
onset: 2024-06-20
Entry 25 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/kidney-lab-creatinine-rejection-1
Resource Observation:
Profile: Lab Result
identifier: ProtectChildId/LBR-2-0002
status: Final
category: Laboratory
code: Creatinine [Mass/volume] in Serum or Plasma
effective: 2024-06-20 08:20:00+0200
performer: Organization University of Padova
value: 2.4 mg/dL (Details: UCUM codemg/dL = 'mg/dL')
interpretation: High
Entry 26 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Condition/KidneyEventBkv1
Resource Condition:
Profile: Clinical Event
identifier: ProtectChildId/CLE-2-0003
clinicalStatus: Active
code: BK Virus Infection
onset: 2024-06-20
Entry 27 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/MedicationStatement/KidneyImmPatReduced1
Resource MedicationStatement:
Profile: Immunosuppressant to Patient
status: active
identifier: ProtectChildId/IMP-2-0003
status: recorded
category: Maintenance
effective: 2024-06-20 --> (ongoing)
dosage
text: Halved in response to biopsy-proven BK-virus nephropathy. Divided twice daily.
DoseAndRates
Dose[x] 0.05 mg/kg (Details: UCUM codemg.kg-1 = 'mg.kg-1')
Entry 28 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Encounter/KidneyVisitRejection2
Resource Encounter:
Profile: Visit
identifier: ProtectChildId/VIS-2-0004
status: completed
class: ambulatory
type: Clinical Event visit
Entry 29 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Condition/KidneyEventRejection1
Resource Condition:
Profile: Clinical Event
identifier: ProtectChildId/CLE-2-0002
clinicalStatus: Active
code: Kidney Rejection Episode
onset: 2024-09-10
Entry 30 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/KidneyImmunologyBiopsy1
Resource Observation:
Profile: Immunological Data
identifier: ProtectChildId/IMD-2-0001
status: Final
category: Laboratory
code: Immunological data panel
effective: 2024-09-10
performer: Organization University of Padova
component
code: Banff rejection category
value: Banff 4 – T cell-mediated rejection
component
code: IHC/IF C4d result
value: false
component
code: Post-transplant anti-HLA DSA class
value: Class II
component
code: MFI category
value: MR (moderate, 2k–4k)
Entry 31 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/kidney-lab-creatinine-rejection-2
Resource Observation:
Profile: Lab Result
identifier: ProtectChildId/LBR-2-0003
status: Final
category: Laboratory
code: Creatinine [Mass/volume] in Serum or Plasma
effective: 2024-09-10 08:30:00+0200
performer: Organization University of Padova
value: 3.1 mg/dL (Details: UCUM codemg/dL = 'mg/dL')
interpretation: High
Entry 32 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/MedicationStatement/KidneyImmPatRejectionTreatment1
Resource MedicationStatement:
Profile: Immunosuppressant to Patient
status: completed
identifier: ProtectChildId/IMP-2-0004
status: recorded
category: Maintenance
effective: 2024-09-10 --> 2024-09-12
dosage
text: Rejection treatment: intravenous methylprednisolone pulse, once daily for three consecutive days, for the rejection episode recorded at this visit. Not maintenance therapy — the DM phase list has no value for rejection treatment.
DoseAndRates
Dose[x] 10 mg/kg (Details: UCUM codemg.kg-1 = 'mg.kg-1')
Entry 33 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Encounter/KidneyVisitTermination1
Resource Encounter:
Profile: Visit
identifier: ProtectChildId/VIS-2-0005
status: completed
class: ambulatory
type: Termination visit
Entry 34 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Condition/KidneyEventGraftFailure1
Resource Condition:
Profile: Clinical Event
identifier: ProtectChildId/CLE-2-0004
clinicalStatus: Active
code: Graft Failure
onset: 2025-01-20
Entry 35 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Observation/kidney-lab-creatinine-termination-1
Resource Observation:
Profile: Lab Result
identifier: ProtectChildId/LBR-2-0004
status: Final
category: Laboratory
code: Creatinine [Mass/volume] in Serum or Plasma
effective: 2025-01-20 09:00:00+0100
performer: Organization University of Padova
value: 5.2 mg/dL (Details: UCUM codemg/dL = 'mg/dL')
interpretation: High
Entry 36 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Procedure/KidneyDialysisChronic1
Resource Procedure:
Profile: Clinical Event Procedure
status: Completed
code: Hemodialysis
Entry 37 - fullUrl = https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/Procedure/KidneyRelisting1
Resource Procedure:
Profile: Clinical Event Procedure
status: Completed
code: Listed for retransplant