PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions

• Content
• Detailed Descriptions
• Mappings
• Examples
• XML
• JSON
• TTL

Resource Profile: Biological Sample

Biological sample linked to a transplant visit, aligned with the DMv1.2 bio_sample table. Patient navigable via Specimen.subject. Visit linked via extension[visit_id]. Analysis intent (genomic_sample / epigenomic_sample) is represented as BioSampleAnalysisRequest (ServiceRequest) resources with specimen = Reference(BioSample). send_ingemm_date maps to the native Specimen.receivedTime.

Usages:

• Refer to this Profile: Biological Sample Analysis Request, Laboratory DiagnosticReport and Lab Result
• Examples for this Profile: Specimen/biosample-example-1

You can also check for usages in the FHIR IG Statistics

Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

• Key Elements Table
• Differential Table
• Snapshot Table
• Statistics/References
• All

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	Specimen	Sample for analysis
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:visit_id	S	1..1	Reference(Visit)	visit_id – Visit during which this sample was collected URL: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/biosample-visit-ref
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	1..1	Identifier	bio_sample_id – primary identifier for the biological sample
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
system	Σ	1..1	uri	The namespace for the identifier value Fixed Value: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/biosample-id
value	Σ	1..1	string	The value that is unique Example General: 123456
status	?!Σ	0..1	code	available | unavailable | unsatisfactory | entered-in-error Binding: SpecimenStatus (required): Codes providing the status/availability of a specimen.
type	SΣ	0..1	CodeableConcept	Specimen material type (blood, tissue, urine, etc.) — NOT analysis intent Binding: v2 Specimen Type (example): The type of the specimen.
subject	SΣ	1..1	Reference(Transplant Recipient)	patient_id – transplant recipient who provided this sample
receivedTime	SΣ	0..1	dateTime	send_ingemm_date – date the sample was received at INGEMM
collection	S	0..1	BackboneElement	Sample collection details
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
collected[x]	Σ	0..1	dateTime	collection_date – sample collection date
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Specimen.identifier.​use	Base	required	IdentifierUse	📍4.0.1	FHIR Std.
Specimen.status	Base	required	SpecimenStatus	📍4.0.1	FHIR Std.
Specimen.type	Base	example	v2 Specimen Type	📦2.9	FHIR Std.

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Specimen	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Specimen	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Specimen	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()

This structure is derived from Specimen

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	Specimen	Sample for analysis
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:visit_id	S	1..1	Reference(Visit)	visit_id – Visit during which this sample was collected URL: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/biosample-visit-ref
identifier	S	1..1	Identifier	bio_sample_id – primary identifier for the biological sample
system		1..1	uri	The namespace for the identifier value Fixed Value: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/biosample-id
value		1..1	string	The value that is unique
type	S	0..1	CodeableConcept	Specimen material type (blood, tissue, urine, etc.) — NOT analysis intent
subject	S	1..1	Reference(Transplant Recipient)	patient_id – transplant recipient who provided this sample
receivedTime	S	0..1	dateTime	send_ingemm_date – date the sample was received at INGEMM
collection	S	0..1	BackboneElement	Sample collection details
collected[x]		0..1	dateTime	collection_date – sample collection date
Documentation for this format

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	Specimen	Sample for analysis
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:visit_id	S	1..1	Reference(Visit)	visit_id – Visit during which this sample was collected URL: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/biosample-visit-ref
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	1..1	Identifier	bio_sample_id – primary identifier for the biological sample
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
type	Σ	0..1	CodeableConcept	Description of identifier Binding: Identifier Type Codes (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.
system	Σ	1..1	uri	The namespace for the identifier value Fixed Value: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/biosample-id
value	Σ	1..1	string	The value that is unique Example General: 123456
period	Σ	0..1	Period	Time period when id is/was valid for use
assigner	Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)
accessionIdentifier	Σ	0..1	Identifier	Identifier assigned by the lab
status	?!Σ	0..1	code	available | unavailable | unsatisfactory | entered-in-error Binding: SpecimenStatus (required): Codes providing the status/availability of a specimen.
type	SΣ	0..1	CodeableConcept	Specimen material type (blood, tissue, urine, etc.) — NOT analysis intent Binding: v2 Specimen Type (example): The type of the specimen.
subject	SΣ	1..1	Reference(Transplant Recipient)	patient_id – transplant recipient who provided this sample
receivedTime	SΣ	0..1	dateTime	send_ingemm_date – date the sample was received at INGEMM
parent		0..*	Reference(Specimen)	Specimen from which this specimen originated
request		0..*	Reference(ServiceRequest)	Why the specimen was collected
collection	S	0..1	BackboneElement	Sample collection details
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
collector	Σ	0..1	Reference(Practitioner | PractitionerRole)	Who collected the specimen
collected[x]	Σ	0..1	dateTime	collection_date – sample collection date
duration	Σ	0..1	Duration	How long it took to collect specimen
quantity		0..1	SimpleQuantity(4.0.1)	The quantity of specimen collected
method		0..1	CodeableConcept	Technique used to perform collection Binding: FHIRSpecimenCollectionMethod (example): The technique that is used to perform the procedure.
bodySite		0..1	CodeableConcept	Anatomical collection site Binding: SNOMEDCTBodyStructures (example): Codes describing anatomical locations. May include laterality.
fastingStatus[x]	Σ	0..1		Whether or how long patient abstained from food and/or drink Binding: v2 Relevant Clincial Information (extensible): Codes describing the fasting status of the patient.
fastingStatusCodeableConcept			CodeableConcept
fastingStatusDuration			Duration
processing		0..*	BackboneElement	Processing and processing step details
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
description		0..1	string	Textual description of procedure
procedure		0..1	CodeableConcept	Indicates the treatment step applied to the specimen Binding: SpecimenProcessingProcedure (example): Type indicating the technique used to process the specimen.
additive		0..*	Reference(Substance)	Material used in the processing step
time[x]		0..1		Date and time of specimen processing
timeDateTime			dateTime
timePeriod			Period
container		0..*	BackboneElement	Direct container of specimen (tube/slide, etc.)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
identifier	Σ	0..*	Identifier	Id for the container
description		0..1	string	Textual description of the container
type		0..1	CodeableConcept	Kind of container directly associated with specimen Binding: SpecimenContainerType (example): Type of specimen container.
capacity		0..1	SimpleQuantity(4.0.1)	Container volume or size
specimenQuantity		0..1	SimpleQuantity(4.0.1)	Quantity of specimen within container
additive[x]		0..1		Additive associated with container Binding: v2 Additive (example): Substance added to specimen container.
additiveCodeableConcept			CodeableConcept
additiveReference			Reference(Substance)
condition	Σ	0..*	CodeableConcept	State of the specimen Binding: v2 Specimen Condition (extensible): Codes describing the state of the specimen.
note		0..*	Annotation	Comments
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Specimen.language	Base	preferred	Common Languages	📍4.0.1	FHIR Std.
Specimen.identifier.​use	Base	required	IdentifierUse	📍4.0.1	FHIR Std.
Specimen.identifier.​type	Base	extensible	IdentifierType	📍4.0.1	FHIR Std.
Specimen.status	Base	required	SpecimenStatus	📍4.0.1	FHIR Std.
Specimen.type	Base	example	v2 Specimen Type	📦2.9	FHIR Std.
Specimen.collection.​method	Base	example	FHIR Specimen Collection Method	📍4.0.1	FHIR Std.
Specimen.collection.​bodySite	Base	example	SNOMED CT Body Structures	📍4.0.1	FHIR Std.
Specimen.collection.​fastingStatus[x]	Base	extensible	v2 Relevant Clincial Information	📦2.9	FHIR Std.
Specimen.processing.​procedure	Base	example	Specimen processing procedure	📍4.0.1	FHIR Std.
Specimen.container.type	Base	example	Specimen Container Type	📍4.0.1	FHIR Std.
Specimen.container.additive[x]	Base	example	v2 Additive	📦2.9	FHIR Std.
Specimen.condition	Base	extensible	v2 Specimen Condition	📦2.9	FHIR Std.

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Specimen	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Specimen	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Specimen	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()

This structure is derived from Specimen

Summary

Mandatory: 6 elements
Must-Support: 6 elements
Fixed: 1 element

Structures

This structure refers to these other structures:

• Transplant Recipient (https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/patient-transplant)

Extensions

This structure refers to these extensions:

• https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/biosample-visit-ref

Key Elements View

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	Specimen	Sample for analysis
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:visit_id	S	1..1	Reference(Visit)	visit_id – Visit during which this sample was collected URL: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/biosample-visit-ref
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	1..1	Identifier	bio_sample_id – primary identifier for the biological sample
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
system	Σ	1..1	uri	The namespace for the identifier value Fixed Value: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/biosample-id
value	Σ	1..1	string	The value that is unique Example General: 123456
status	?!Σ	0..1	code	available | unavailable | unsatisfactory | entered-in-error Binding: SpecimenStatus (required): Codes providing the status/availability of a specimen.
type	SΣ	0..1	CodeableConcept	Specimen material type (blood, tissue, urine, etc.) — NOT analysis intent Binding: v2 Specimen Type (example): The type of the specimen.
subject	SΣ	1..1	Reference(Transplant Recipient)	patient_id – transplant recipient who provided this sample
receivedTime	SΣ	0..1	dateTime	send_ingemm_date – date the sample was received at INGEMM
collection	S	0..1	BackboneElement	Sample collection details
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
collected[x]	Σ	0..1	dateTime	collection_date – sample collection date
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Specimen.identifier.​use	Base	required	IdentifierUse	📍4.0.1	FHIR Std.
Specimen.status	Base	required	SpecimenStatus	📍4.0.1	FHIR Std.
Specimen.type	Base	example	v2 Specimen Type	📦2.9	FHIR Std.

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Specimen	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Specimen	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Specimen	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()

Differential View

This structure is derived from Specimen

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	Specimen	Sample for analysis
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:visit_id	S	1..1	Reference(Visit)	visit_id – Visit during which this sample was collected URL: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/biosample-visit-ref
identifier	S	1..1	Identifier	bio_sample_id – primary identifier for the biological sample
system		1..1	uri	The namespace for the identifier value Fixed Value: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/biosample-id
value		1..1	string	The value that is unique
type	S	0..1	CodeableConcept	Specimen material type (blood, tissue, urine, etc.) — NOT analysis intent
subject	S	1..1	Reference(Transplant Recipient)	patient_id – transplant recipient who provided this sample
receivedTime	S	0..1	dateTime	send_ingemm_date – date the sample was received at INGEMM
collection	S	0..1	BackboneElement	Sample collection details
collected[x]		0..1	dateTime	collection_date – sample collection date
Documentation for this format

Snapshot View

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	Specimen	Sample for analysis
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:visit_id	S	1..1	Reference(Visit)	visit_id – Visit during which this sample was collected URL: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/biosample-visit-ref
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	1..1	Identifier	bio_sample_id – primary identifier for the biological sample
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
type	Σ	0..1	CodeableConcept	Description of identifier Binding: Identifier Type Codes (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.
system	Σ	1..1	uri	The namespace for the identifier value Fixed Value: https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/NamingSystem/biosample-id
value	Σ	1..1	string	The value that is unique Example General: 123456
period	Σ	0..1	Period	Time period when id is/was valid for use
assigner	Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)
accessionIdentifier	Σ	0..1	Identifier	Identifier assigned by the lab
status	?!Σ	0..1	code	available | unavailable | unsatisfactory | entered-in-error Binding: SpecimenStatus (required): Codes providing the status/availability of a specimen.
type	SΣ	0..1	CodeableConcept	Specimen material type (blood, tissue, urine, etc.) — NOT analysis intent Binding: v2 Specimen Type (example): The type of the specimen.
subject	SΣ	1..1	Reference(Transplant Recipient)	patient_id – transplant recipient who provided this sample
receivedTime	SΣ	0..1	dateTime	send_ingemm_date – date the sample was received at INGEMM
parent		0..*	Reference(Specimen)	Specimen from which this specimen originated
request		0..*	Reference(ServiceRequest)	Why the specimen was collected
collection	S	0..1	BackboneElement	Sample collection details
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
collector	Σ	0..1	Reference(Practitioner | PractitionerRole)	Who collected the specimen
collected[x]	Σ	0..1	dateTime	collection_date – sample collection date
duration	Σ	0..1	Duration	How long it took to collect specimen
quantity		0..1	SimpleQuantity(4.0.1)	The quantity of specimen collected
method		0..1	CodeableConcept	Technique used to perform collection Binding: FHIRSpecimenCollectionMethod (example): The technique that is used to perform the procedure.
bodySite		0..1	CodeableConcept	Anatomical collection site Binding: SNOMEDCTBodyStructures (example): Codes describing anatomical locations. May include laterality.
fastingStatus[x]	Σ	0..1		Whether or how long patient abstained from food and/or drink Binding: v2 Relevant Clincial Information (extensible): Codes describing the fasting status of the patient.
fastingStatusCodeableConcept			CodeableConcept
fastingStatusDuration			Duration
processing		0..*	BackboneElement	Processing and processing step details
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
description		0..1	string	Textual description of procedure
procedure		0..1	CodeableConcept	Indicates the treatment step applied to the specimen Binding: SpecimenProcessingProcedure (example): Type indicating the technique used to process the specimen.
additive		0..*	Reference(Substance)	Material used in the processing step
time[x]		0..1		Date and time of specimen processing
timeDateTime			dateTime
timePeriod			Period
container		0..*	BackboneElement	Direct container of specimen (tube/slide, etc.)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
identifier	Σ	0..*	Identifier	Id for the container
description		0..1	string	Textual description of the container
type		0..1	CodeableConcept	Kind of container directly associated with specimen Binding: SpecimenContainerType (example): Type of specimen container.
capacity		0..1	SimpleQuantity(4.0.1)	Container volume or size
specimenQuantity		0..1	SimpleQuantity(4.0.1)	Quantity of specimen within container
additive[x]		0..1		Additive associated with container Binding: v2 Additive (example): Substance added to specimen container.
additiveCodeableConcept			CodeableConcept
additiveReference			Reference(Substance)
condition	Σ	0..*	CodeableConcept	State of the specimen Binding: v2 Specimen Condition (extensible): Codes describing the state of the specimen.
note		0..*	Annotation	Comments
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Specimen.language	Base	preferred	Common Languages	📍4.0.1	FHIR Std.
Specimen.identifier.​use	Base	required	IdentifierUse	📍4.0.1	FHIR Std.
Specimen.identifier.​type	Base	extensible	IdentifierType	📍4.0.1	FHIR Std.
Specimen.status	Base	required	SpecimenStatus	📍4.0.1	FHIR Std.
Specimen.type	Base	example	v2 Specimen Type	📦2.9	FHIR Std.
Specimen.collection.​method	Base	example	FHIR Specimen Collection Method	📍4.0.1	FHIR Std.
Specimen.collection.​bodySite	Base	example	SNOMED CT Body Structures	📍4.0.1	FHIR Std.
Specimen.collection.​fastingStatus[x]	Base	extensible	v2 Relevant Clincial Information	📦2.9	FHIR Std.
Specimen.processing.​procedure	Base	example	Specimen processing procedure	📍4.0.1	FHIR Std.
Specimen.container.type	Base	example	Specimen Container Type	📍4.0.1	FHIR Std.
Specimen.container.additive[x]	Base	example	v2 Additive	📦2.9	FHIR Std.
Specimen.condition	Base	extensible	v2 Specimen Condition	📦2.9	FHIR Std.

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Specimen	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Specimen	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Specimen	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()

This structure is derived from Specimen

Summary

Mandatory: 6 elements
Must-Support: 6 elements
Fixed: 1 element

Structures

This structure refers to these other structures:

• Transplant Recipient (https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/patient-transplant)

Extensions

This structure refers to these extensions:

• https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/StructureDefinition/biosample-visit-ref

Other representations of profile: CSV, Excel, Schematron