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PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build -

PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build

PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions

: Immunological Data Component Codes - TTL Representation

Draft as of 2026-08-11

Raw ttl | Download


@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/CodeSystem/imm-data-component-cs> a fhir:CodeSystem ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:Resource.id [ fhir:value "imm-data-component-cs"] ;
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ] ;
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem imm-data-component-cs</b></p><a name=\"imm-data-component-cs\"> </a><a name=\"hcimm-data-component-cs\"> </a><p>This case-sensitive code system <code>https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">hla-a-1<a name=\"imm-data-component-cs-hla-a-1\"> </a></td><td>HLA-A allele 1</td><td>HLA-A locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-a-2<a name=\"imm-data-component-cs-hla-a-2\"> </a></td><td>HLA-A allele 2</td><td>HLA-A locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-b-1<a name=\"imm-data-component-cs-hla-b-1\"> </a></td><td>HLA-B allele 1</td><td>HLA-B locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-b-2<a name=\"imm-data-component-cs-hla-b-2\"> </a></td><td>HLA-B allele 2</td><td>HLA-B locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-c-1<a name=\"imm-data-component-cs-hla-c-1\"> </a></td><td>HLA-C allele 1</td><td>HLA-C locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-c-2<a name=\"imm-data-component-cs-hla-c-2\"> </a></td><td>HLA-C allele 2</td><td>HLA-C locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-drb1-1<a name=\"imm-data-component-cs-hla-drb1-1\"> </a></td><td>HLA-DRB1 allele 1</td><td>HLA-DRB1 locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-drb1-2<a name=\"imm-data-component-cs-hla-drb1-2\"> </a></td><td>HLA-DRB1 allele 2</td><td>HLA-DRB1 locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dp-1<a name=\"imm-data-component-cs-hla-dp-1\"> </a></td><td>HLA-DP allele 1</td><td>HLA-DP locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dp-2<a name=\"imm-data-component-cs-hla-dp-2\"> </a></td><td>HLA-DP allele 2</td><td>HLA-DP locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dqb1-1<a name=\"imm-data-component-cs-hla-dqb1-1\"> </a></td><td>HLA-DQB1 allele 1</td><td>HLA-DQB1 locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dqb1-2<a name=\"imm-data-component-cs-hla-dqb1-2\"> </a></td><td>HLA-DQB1 allele 2</td><td>HLA-DQB1 locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">pre-tx-dsa<a name=\"imm-data-component-cs-pre-tx-dsa\"> </a></td><td>Pre-transplant anti-HLA DSA</td><td>Pre-transplant anti-HLA donor-specific antibody status.</td></tr><tr><td style=\"white-space:nowrap\">post-tx-dsa-class<a name=\"imm-data-component-cs-post-tx-dsa-class\"> </a></td><td>Post-transplant anti-HLA DSA class</td><td>HLA class of post-transplant anti-HLA donor-specific antibody.</td></tr><tr><td style=\"white-space:nowrap\">mfi-category<a name=\"imm-data-component-cs-mfi-category\"> </a></td><td>MFI category</td><td>Mean fluorescence intensity category of the detected antibody.</td></tr><tr><td style=\"white-space:nowrap\">banff-category<a name=\"imm-data-component-cs-banff-category\"> </a></td><td>Banff rejection category</td><td>Banff classification category assigned on allograft biopsy.</td></tr><tr><td style=\"white-space:nowrap\">ihc-if-c4d<a name=\"imm-data-component-cs-ihc-if-c4d\"> </a></td><td>IHC/IF C4d result</td><td>C4d result by immunohistochemistry / immunofluorescence.</td></tr><tr><td style=\"white-space:nowrap\">if-result<a name=\"imm-data-component-cs-if-result\"> </a></td><td>Immunofluorescence result</td><td>Immunofluorescence examination result.</td></tr><tr><td style=\"white-space:nowrap\">c4d-result<a name=\"imm-data-component-cs-c4d-result\"> </a></td><td>C4d result detail</td><td>Detailed C4d staining result.</td></tr><tr><td style=\"white-space:nowrap\">anca<a name=\"imm-data-component-cs-anca\"> </a></td><td>ANCA result</td><td>Anti-neutrophil cytoplasmic antibody (ANCA) result.</td></tr><tr><td style=\"white-space:nowrap\">antibody-type<a name=\"imm-data-component-cs-antibody-type\"> </a></td><td>Antibody type specification</td><td>Specification of the antibody type detected.</td></tr><tr><td style=\"white-space:nowrap\">anti-hla-antibodies<a name=\"imm-data-component-cs-anti-hla-antibodies\"> </a></td><td>Presence of anti-HLA antibodies</td><td>Presence of anti-HLA antibodies.</td></tr></table></div>"
  ] ;
  fhir:CodeSystem.url [ fhir:value "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs"] ;
  fhir:CodeSystem.version [ fhir:value "0.1.0-ci-build"] ;
  fhir:CodeSystem.name [ fhir:value "ImmDataComponentCS"] ;
  fhir:CodeSystem.title [ fhir:value "Immunological Data Component Codes"] ;
  fhir:CodeSystem.status [ fhir:value "draft"] ;
  fhir:CodeSystem.experimental [ fhir:value "true"^^xsd:boolean] ;
  fhir:CodeSystem.date [ fhir:value "2026-08-11T12:50:29+00:00"^^xsd:dateTime] ;
  fhir:CodeSystem.publisher [ fhir:value "Protect Child"] ;
  fhir:CodeSystem.contact [
     fhir:index 0 ;
     fhir:ContactDetail.name [ fhir:value "Protect Child" ] ;
     fhir:ContactDetail.telecom [
       fhir:index 0 ;
       fhir:ContactPoint.system [ fhir:value "url" ] ;
       fhir:ContactPoint.value [ fhir:value "https://protect-child.eu/" ]
     ]
  ] ;
  fhir:CodeSystem.description [ fhir:value "Local component codes for immunological data panel slices. HLA allele positions use per-position codes (hla-a-1, hla-a-2, …) so that pattern-discriminator slicing can distinguish allele 1 from allele 2. Non-HLA codes cover DSA, Banff, C4d, ANCA, and related fields."] ;
  fhir:CodeSystem.caseSensitive [ fhir:value "true"^^xsd:boolean] ;
  fhir:CodeSystem.content [ fhir:value "complete"] ;
  fhir:CodeSystem.count [ fhir:value "22"^^xsd:nonNegativeInteger] ;
  fhir:CodeSystem.concept [
     fhir:index 0 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-a-1" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-A allele 1" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-A locus, allele 1 (IMGT/HLA typing)." ]
  ], [
     fhir:index 1 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-a-2" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-A allele 2" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-A locus, allele 2 (IMGT/HLA typing)." ]
  ], [
     fhir:index 2 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-b-1" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-B allele 1" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-B locus, allele 1 (IMGT/HLA typing)." ]
  ], [
     fhir:index 3 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-b-2" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-B allele 2" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-B locus, allele 2 (IMGT/HLA typing)." ]
  ], [
     fhir:index 4 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-c-1" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-C allele 1" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-C locus, allele 1 (IMGT/HLA typing)." ]
  ], [
     fhir:index 5 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-c-2" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-C allele 2" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-C locus, allele 2 (IMGT/HLA typing)." ]
  ], [
     fhir:index 6 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-drb1-1" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-DRB1 allele 1" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-DRB1 locus, allele 1 (IMGT/HLA typing)." ]
  ], [
     fhir:index 7 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-drb1-2" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-DRB1 allele 2" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-DRB1 locus, allele 2 (IMGT/HLA typing)." ]
  ], [
     fhir:index 8 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-dp-1" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-DP allele 1" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-DP locus, allele 1 (IMGT/HLA typing)." ]
  ], [
     fhir:index 9 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-dp-2" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-DP allele 2" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-DP locus, allele 2 (IMGT/HLA typing)." ]
  ], [
     fhir:index 10 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-dqb1-1" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-DQB1 allele 1" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-DQB1 locus, allele 1 (IMGT/HLA typing)." ]
  ], [
     fhir:index 11 ;
     fhir:CodeSystem.concept.code [ fhir:value "hla-dqb1-2" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "HLA-DQB1 allele 2" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA-DQB1 locus, allele 2 (IMGT/HLA typing)." ]
  ], [
     fhir:index 12 ;
     fhir:CodeSystem.concept.code [ fhir:value "pre-tx-dsa" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "Pre-transplant anti-HLA DSA" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "Pre-transplant anti-HLA donor-specific antibody status." ]
  ], [
     fhir:index 13 ;
     fhir:CodeSystem.concept.code [ fhir:value "post-tx-dsa-class" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "Post-transplant anti-HLA DSA class" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "HLA class of post-transplant anti-HLA donor-specific antibody." ]
  ], [
     fhir:index 14 ;
     fhir:CodeSystem.concept.code [ fhir:value "mfi-category" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "MFI category" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "Mean fluorescence intensity category of the detected antibody." ]
  ], [
     fhir:index 15 ;
     fhir:CodeSystem.concept.code [ fhir:value "banff-category" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "Banff rejection category" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "Banff classification category assigned on allograft biopsy." ]
  ], [
     fhir:index 16 ;
     fhir:CodeSystem.concept.code [ fhir:value "ihc-if-c4d" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "IHC/IF C4d result" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "C4d result by immunohistochemistry / immunofluorescence." ]
  ], [
     fhir:index 17 ;
     fhir:CodeSystem.concept.code [ fhir:value "if-result" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "Immunofluorescence result" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "Immunofluorescence examination result." ]
  ], [
     fhir:index 18 ;
     fhir:CodeSystem.concept.code [ fhir:value "c4d-result" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "C4d result detail" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "Detailed C4d staining result." ]
  ], [
     fhir:index 19 ;
     fhir:CodeSystem.concept.code [ fhir:value "anca" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "ANCA result" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "Anti-neutrophil cytoplasmic antibody (ANCA) result." ]
  ], [
     fhir:index 20 ;
     fhir:CodeSystem.concept.code [ fhir:value "antibody-type" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "Antibody type specification" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "Specification of the antibody type detected." ]
  ], [
     fhir:index 21 ;
     fhir:CodeSystem.concept.code [ fhir:value "anti-hla-antibodies" ] ;
     fhir:CodeSystem.concept.display [ fhir:value "Presence of anti-HLA antibodies" ] ;
     fhir:CodeSystem.concept.definition [ fhir:value "Presence of anti-HLA antibodies." ]
  ] .

# - ontology header ------------------------------------------------------------

<http://hl7.org/fhir/CodeSystem/imm-data-component-cs.ttl> a owl:Ontology ;
  owl:imports fhir:fhir.ttl ;
  owl:versionIRI <http://build.fhir.org/CodeSystem/imm-data-component-cs.ttl> .