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PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build -

PROTECT-CHILD Pediatric Transplant Data Implementation Guide
0.1.0-ci-build - ci-build

PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions

: Immunological Data Component Codes - JSON Representation

Draft as of 2026-08-11

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{
  "resourceType" : "CodeSystem",
  "id" : "imm-data-component-cs",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem imm-data-component-cs</b></p><a name=\"imm-data-component-cs\"> </a><a name=\"hcimm-data-component-cs\"> </a><p>This case-sensitive code system <code>https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">hla-a-1<a name=\"imm-data-component-cs-hla-a-1\"> </a></td><td>HLA-A allele 1</td><td>HLA-A locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-a-2<a name=\"imm-data-component-cs-hla-a-2\"> </a></td><td>HLA-A allele 2</td><td>HLA-A locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-b-1<a name=\"imm-data-component-cs-hla-b-1\"> </a></td><td>HLA-B allele 1</td><td>HLA-B locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-b-2<a name=\"imm-data-component-cs-hla-b-2\"> </a></td><td>HLA-B allele 2</td><td>HLA-B locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-c-1<a name=\"imm-data-component-cs-hla-c-1\"> </a></td><td>HLA-C allele 1</td><td>HLA-C locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-c-2<a name=\"imm-data-component-cs-hla-c-2\"> </a></td><td>HLA-C allele 2</td><td>HLA-C locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-drb1-1<a name=\"imm-data-component-cs-hla-drb1-1\"> </a></td><td>HLA-DRB1 allele 1</td><td>HLA-DRB1 locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-drb1-2<a name=\"imm-data-component-cs-hla-drb1-2\"> </a></td><td>HLA-DRB1 allele 2</td><td>HLA-DRB1 locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dp-1<a name=\"imm-data-component-cs-hla-dp-1\"> </a></td><td>HLA-DP allele 1</td><td>HLA-DP locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dp-2<a name=\"imm-data-component-cs-hla-dp-2\"> </a></td><td>HLA-DP allele 2</td><td>HLA-DP locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dqb1-1<a name=\"imm-data-component-cs-hla-dqb1-1\"> </a></td><td>HLA-DQB1 allele 1</td><td>HLA-DQB1 locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dqb1-2<a name=\"imm-data-component-cs-hla-dqb1-2\"> </a></td><td>HLA-DQB1 allele 2</td><td>HLA-DQB1 locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">pre-tx-dsa<a name=\"imm-data-component-cs-pre-tx-dsa\"> </a></td><td>Pre-transplant anti-HLA DSA</td><td>Pre-transplant anti-HLA donor-specific antibody status.</td></tr><tr><td style=\"white-space:nowrap\">post-tx-dsa-class<a name=\"imm-data-component-cs-post-tx-dsa-class\"> </a></td><td>Post-transplant anti-HLA DSA class</td><td>HLA class of post-transplant anti-HLA donor-specific antibody.</td></tr><tr><td style=\"white-space:nowrap\">mfi-category<a name=\"imm-data-component-cs-mfi-category\"> </a></td><td>MFI category</td><td>Mean fluorescence intensity category of the detected antibody.</td></tr><tr><td style=\"white-space:nowrap\">banff-category<a name=\"imm-data-component-cs-banff-category\"> </a></td><td>Banff rejection category</td><td>Banff classification category assigned on allograft biopsy.</td></tr><tr><td style=\"white-space:nowrap\">ihc-if-c4d<a name=\"imm-data-component-cs-ihc-if-c4d\"> </a></td><td>IHC/IF C4d result</td><td>C4d result by immunohistochemistry / immunofluorescence.</td></tr><tr><td style=\"white-space:nowrap\">if-result<a name=\"imm-data-component-cs-if-result\"> </a></td><td>Immunofluorescence result</td><td>Immunofluorescence examination result.</td></tr><tr><td style=\"white-space:nowrap\">c4d-result<a name=\"imm-data-component-cs-c4d-result\"> </a></td><td>C4d result detail</td><td>Detailed C4d staining result.</td></tr><tr><td style=\"white-space:nowrap\">anca<a name=\"imm-data-component-cs-anca\"> </a></td><td>ANCA result</td><td>Anti-neutrophil cytoplasmic antibody (ANCA) result.</td></tr><tr><td style=\"white-space:nowrap\">antibody-type<a name=\"imm-data-component-cs-antibody-type\"> </a></td><td>Antibody type specification</td><td>Specification of the antibody type detected.</td></tr><tr><td style=\"white-space:nowrap\">anti-hla-antibodies<a name=\"imm-data-component-cs-anti-hla-antibodies\"> </a></td><td>Presence of anti-HLA antibodies</td><td>Presence of anti-HLA antibodies.</td></tr></table></div>"
  },
  "url" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
  "version" : "0.1.0-ci-build",
  "name" : "ImmDataComponentCS",
  "title" : "Immunological Data Component Codes",
  "status" : "draft",
  "experimental" : true,
  "date" : "2026-08-11T12:50:29+00:00",
  "publisher" : "Protect Child",
  "contact" : [
    {
      "name" : "Protect Child",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://protect-child.eu/"
        }
      ]
    }
  ],
  "description" : "Local component codes for immunological data panel slices. HLA allele positions use per-position codes (hla-a-1, hla-a-2, …) so that pattern-discriminator slicing can distinguish allele 1 from allele 2. Non-HLA codes cover DSA, Banff, C4d, ANCA, and related fields.",
  "caseSensitive" : true,
  "content" : "complete",
  "count" : 22,
  "concept" : [
    {
      "code" : "hla-a-1",
      "display" : "HLA-A allele 1",
      "definition" : "HLA-A locus, allele 1 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-a-2",
      "display" : "HLA-A allele 2",
      "definition" : "HLA-A locus, allele 2 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-b-1",
      "display" : "HLA-B allele 1",
      "definition" : "HLA-B locus, allele 1 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-b-2",
      "display" : "HLA-B allele 2",
      "definition" : "HLA-B locus, allele 2 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-c-1",
      "display" : "HLA-C allele 1",
      "definition" : "HLA-C locus, allele 1 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-c-2",
      "display" : "HLA-C allele 2",
      "definition" : "HLA-C locus, allele 2 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-drb1-1",
      "display" : "HLA-DRB1 allele 1",
      "definition" : "HLA-DRB1 locus, allele 1 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-drb1-2",
      "display" : "HLA-DRB1 allele 2",
      "definition" : "HLA-DRB1 locus, allele 2 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-dp-1",
      "display" : "HLA-DP allele 1",
      "definition" : "HLA-DP locus, allele 1 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-dp-2",
      "display" : "HLA-DP allele 2",
      "definition" : "HLA-DP locus, allele 2 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-dqb1-1",
      "display" : "HLA-DQB1 allele 1",
      "definition" : "HLA-DQB1 locus, allele 1 (IMGT/HLA typing)."
    },
    {
      "code" : "hla-dqb1-2",
      "display" : "HLA-DQB1 allele 2",
      "definition" : "HLA-DQB1 locus, allele 2 (IMGT/HLA typing)."
    },
    {
      "code" : "pre-tx-dsa",
      "display" : "Pre-transplant anti-HLA DSA",
      "definition" : "Pre-transplant anti-HLA donor-specific antibody status."
    },
    {
      "code" : "post-tx-dsa-class",
      "display" : "Post-transplant anti-HLA DSA class",
      "definition" : "HLA class of post-transplant anti-HLA donor-specific antibody."
    },
    {
      "code" : "mfi-category",
      "display" : "MFI category",
      "definition" : "Mean fluorescence intensity category of the detected antibody."
    },
    {
      "code" : "banff-category",
      "display" : "Banff rejection category",
      "definition" : "Banff classification category assigned on allograft biopsy."
    },
    {
      "code" : "ihc-if-c4d",
      "display" : "IHC/IF C4d result",
      "definition" : "C4d result by immunohistochemistry / immunofluorescence."
    },
    {
      "code" : "if-result",
      "display" : "Immunofluorescence result",
      "definition" : "Immunofluorescence examination result."
    },
    {
      "code" : "c4d-result",
      "display" : "C4d result detail",
      "definition" : "Detailed C4d staining result."
    },
    {
      "code" : "anca",
      "display" : "ANCA result",
      "definition" : "Anti-neutrophil cytoplasmic antibody (ANCA) result."
    },
    {
      "code" : "antibody-type",
      "display" : "Antibody type specification",
      "definition" : "Specification of the antibody type detected."
    },
    {
      "code" : "anti-hla-antibodies",
      "display" : "Presence of anti-HLA antibodies",
      "definition" : "Presence of anti-HLA antibodies."
    }
  ]
}