PROTECT-CHILD Pediatric Transplant Data Implementation Guide, published by Protect Child. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/protect-child/ and changes regularly. See the Directory of published versions
| Draft as of 2026-08-11 |
{
"resourceType" : "CodeSystem",
"id" : "imm-data-component-cs",
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem imm-data-component-cs</b></p><a name=\"imm-data-component-cs\"> </a><a name=\"hcimm-data-component-cs\"> </a><p>This case-sensitive code system <code>https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">hla-a-1<a name=\"imm-data-component-cs-hla-a-1\"> </a></td><td>HLA-A allele 1</td><td>HLA-A locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-a-2<a name=\"imm-data-component-cs-hla-a-2\"> </a></td><td>HLA-A allele 2</td><td>HLA-A locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-b-1<a name=\"imm-data-component-cs-hla-b-1\"> </a></td><td>HLA-B allele 1</td><td>HLA-B locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-b-2<a name=\"imm-data-component-cs-hla-b-2\"> </a></td><td>HLA-B allele 2</td><td>HLA-B locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-c-1<a name=\"imm-data-component-cs-hla-c-1\"> </a></td><td>HLA-C allele 1</td><td>HLA-C locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-c-2<a name=\"imm-data-component-cs-hla-c-2\"> </a></td><td>HLA-C allele 2</td><td>HLA-C locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-drb1-1<a name=\"imm-data-component-cs-hla-drb1-1\"> </a></td><td>HLA-DRB1 allele 1</td><td>HLA-DRB1 locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-drb1-2<a name=\"imm-data-component-cs-hla-drb1-2\"> </a></td><td>HLA-DRB1 allele 2</td><td>HLA-DRB1 locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dp-1<a name=\"imm-data-component-cs-hla-dp-1\"> </a></td><td>HLA-DP allele 1</td><td>HLA-DP locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dp-2<a name=\"imm-data-component-cs-hla-dp-2\"> </a></td><td>HLA-DP allele 2</td><td>HLA-DP locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dqb1-1<a name=\"imm-data-component-cs-hla-dqb1-1\"> </a></td><td>HLA-DQB1 allele 1</td><td>HLA-DQB1 locus, allele 1 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">hla-dqb1-2<a name=\"imm-data-component-cs-hla-dqb1-2\"> </a></td><td>HLA-DQB1 allele 2</td><td>HLA-DQB1 locus, allele 2 (IMGT/HLA typing).</td></tr><tr><td style=\"white-space:nowrap\">pre-tx-dsa<a name=\"imm-data-component-cs-pre-tx-dsa\"> </a></td><td>Pre-transplant anti-HLA DSA</td><td>Pre-transplant anti-HLA donor-specific antibody status.</td></tr><tr><td style=\"white-space:nowrap\">post-tx-dsa-class<a name=\"imm-data-component-cs-post-tx-dsa-class\"> </a></td><td>Post-transplant anti-HLA DSA class</td><td>HLA class of post-transplant anti-HLA donor-specific antibody.</td></tr><tr><td style=\"white-space:nowrap\">mfi-category<a name=\"imm-data-component-cs-mfi-category\"> </a></td><td>MFI category</td><td>Mean fluorescence intensity category of the detected antibody.</td></tr><tr><td style=\"white-space:nowrap\">banff-category<a name=\"imm-data-component-cs-banff-category\"> </a></td><td>Banff rejection category</td><td>Banff classification category assigned on allograft biopsy.</td></tr><tr><td style=\"white-space:nowrap\">ihc-if-c4d<a name=\"imm-data-component-cs-ihc-if-c4d\"> </a></td><td>IHC/IF C4d result</td><td>C4d result by immunohistochemistry / immunofluorescence.</td></tr><tr><td style=\"white-space:nowrap\">if-result<a name=\"imm-data-component-cs-if-result\"> </a></td><td>Immunofluorescence result</td><td>Immunofluorescence examination result.</td></tr><tr><td style=\"white-space:nowrap\">c4d-result<a name=\"imm-data-component-cs-c4d-result\"> </a></td><td>C4d result detail</td><td>Detailed C4d staining result.</td></tr><tr><td style=\"white-space:nowrap\">anca<a name=\"imm-data-component-cs-anca\"> </a></td><td>ANCA result</td><td>Anti-neutrophil cytoplasmic antibody (ANCA) result.</td></tr><tr><td style=\"white-space:nowrap\">antibody-type<a name=\"imm-data-component-cs-antibody-type\"> </a></td><td>Antibody type specification</td><td>Specification of the antibody type detected.</td></tr><tr><td style=\"white-space:nowrap\">anti-hla-antibodies<a name=\"imm-data-component-cs-anti-hla-antibodies\"> </a></td><td>Presence of anti-HLA antibodies</td><td>Presence of anti-HLA antibodies.</td></tr></table></div>"
},
"url" : "https://hl7.eu/fhir/ig/hl7.eu.fhir.protect-child/CodeSystem/imm-data-component-cs",
"version" : "0.1.0-ci-build",
"name" : "ImmDataComponentCS",
"title" : "Immunological Data Component Codes",
"status" : "draft",
"experimental" : true,
"date" : "2026-08-11T12:50:29+00:00",
"publisher" : "Protect Child",
"contact" : [
{
"name" : "Protect Child",
"telecom" : [
{
"system" : "url",
"value" : "https://protect-child.eu/"
}
]
}
],
"description" : "Local component codes for immunological data panel slices. HLA allele positions use per-position codes (hla-a-1, hla-a-2, …) so that pattern-discriminator slicing can distinguish allele 1 from allele 2. Non-HLA codes cover DSA, Banff, C4d, ANCA, and related fields.",
"caseSensitive" : true,
"content" : "complete",
"count" : 22,
"concept" : [
{
"code" : "hla-a-1",
"display" : "HLA-A allele 1",
"definition" : "HLA-A locus, allele 1 (IMGT/HLA typing)."
},
{
"code" : "hla-a-2",
"display" : "HLA-A allele 2",
"definition" : "HLA-A locus, allele 2 (IMGT/HLA typing)."
},
{
"code" : "hla-b-1",
"display" : "HLA-B allele 1",
"definition" : "HLA-B locus, allele 1 (IMGT/HLA typing)."
},
{
"code" : "hla-b-2",
"display" : "HLA-B allele 2",
"definition" : "HLA-B locus, allele 2 (IMGT/HLA typing)."
},
{
"code" : "hla-c-1",
"display" : "HLA-C allele 1",
"definition" : "HLA-C locus, allele 1 (IMGT/HLA typing)."
},
{
"code" : "hla-c-2",
"display" : "HLA-C allele 2",
"definition" : "HLA-C locus, allele 2 (IMGT/HLA typing)."
},
{
"code" : "hla-drb1-1",
"display" : "HLA-DRB1 allele 1",
"definition" : "HLA-DRB1 locus, allele 1 (IMGT/HLA typing)."
},
{
"code" : "hla-drb1-2",
"display" : "HLA-DRB1 allele 2",
"definition" : "HLA-DRB1 locus, allele 2 (IMGT/HLA typing)."
},
{
"code" : "hla-dp-1",
"display" : "HLA-DP allele 1",
"definition" : "HLA-DP locus, allele 1 (IMGT/HLA typing)."
},
{
"code" : "hla-dp-2",
"display" : "HLA-DP allele 2",
"definition" : "HLA-DP locus, allele 2 (IMGT/HLA typing)."
},
{
"code" : "hla-dqb1-1",
"display" : "HLA-DQB1 allele 1",
"definition" : "HLA-DQB1 locus, allele 1 (IMGT/HLA typing)."
},
{
"code" : "hla-dqb1-2",
"display" : "HLA-DQB1 allele 2",
"definition" : "HLA-DQB1 locus, allele 2 (IMGT/HLA typing)."
},
{
"code" : "pre-tx-dsa",
"display" : "Pre-transplant anti-HLA DSA",
"definition" : "Pre-transplant anti-HLA donor-specific antibody status."
},
{
"code" : "post-tx-dsa-class",
"display" : "Post-transplant anti-HLA DSA class",
"definition" : "HLA class of post-transplant anti-HLA donor-specific antibody."
},
{
"code" : "mfi-category",
"display" : "MFI category",
"definition" : "Mean fluorescence intensity category of the detected antibody."
},
{
"code" : "banff-category",
"display" : "Banff rejection category",
"definition" : "Banff classification category assigned on allograft biopsy."
},
{
"code" : "ihc-if-c4d",
"display" : "IHC/IF C4d result",
"definition" : "C4d result by immunohistochemistry / immunofluorescence."
},
{
"code" : "if-result",
"display" : "Immunofluorescence result",
"definition" : "Immunofluorescence examination result."
},
{
"code" : "c4d-result",
"display" : "C4d result detail",
"definition" : "Detailed C4d staining result."
},
{
"code" : "anca",
"display" : "ANCA result",
"definition" : "Anti-neutrophil cytoplasmic antibody (ANCA) result."
},
{
"code" : "antibody-type",
"display" : "Antibody type specification",
"definition" : "Specification of the antibody type detected."
},
{
"code" : "anti-hla-antibodies",
"display" : "Presence of anti-HLA antibodies",
"definition" : "Presence of anti-HLA antibodies."
}
]
}