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Example CodeSystem/oligo-nucleotide-type (XML)

Responsible Owner: Biomedical Research and Regulation Work GroupStandards Status: Informative

Raw XML (canonical form + also see XML Format Specification)

Definition for Code SystemOligoNucleotideTypeExample

<?xml version="1.0" encoding="UTF-8"?>

<CodeSystem xmlns="http://hl7.org/fhir">
  <id value="oligo-nucleotide-type"/> 
  <meta> 
    <lastUpdated value="2026-06-23T16:20:19.822+00:00"/> 
  </meta> 
  <text> 
    <status value="generated"/> 
    <div xmlns="http://www.w3.org/1999/xhtml">
      <p class="res-header-id">
        <b> Generated Narrative: CodeSystem oligo-nucleotide-type</b> 
      </p> 
      <a name="oligo-nucleotide-type"> </a> 
      <a name="hcoligo-nucleotide-type"> </a> 
      <p> This case-sensitive code system 
        <code> http://hl7.org/fhir/oligo-nucleotide-type</code>  defines the following codes:
      </p> 
      <table class="codes">
        <tr> 
          <td style="white-space:nowrap">
            <b> Code</b> 
          </td> 
          <td> 
            <b> Display</b> 
          </td> 
          <td> 
            <b> Definition</b> 
          </td> 
        </tr> 
        <tr> 
          <td style="white-space:nowrap">antisense
            <a name="oligo-nucleotide-type-antisense"> </a> 
          </td> 
          <td> Antisense oligonucleotide</td> 
          <td> An antisense oligonucleotide (ASO) that binds to a complementary mRNA sequence
             to inhibit gene expression.</td> 
        </tr> 
        <tr> 
          <td style="white-space:nowrap">sirna
            <a name="oligo-nucleotide-type-sirna"> </a> 
          </td> 
          <td> Small interfering RNA (siRNA)</td> 
          <td> A short double-stranded RNA that triggers degradation of a target mRNA through
             the RNA interference pathway.</td> 
        </tr> 
        <tr> 
          <td style="white-space:nowrap">mirna
            <a name="oligo-nucleotide-type-mirna"> </a> 
          </td> 
          <td> MicroRNA (miRNA)</td> 
          <td> A short non-coding RNA that regulates gene expression by base-pairing with target
             mRNAs.</td> 
        </tr> 
        <tr> 
          <td style="white-space:nowrap">aptamer
            <a name="oligo-nucleotide-type-aptamer"> </a> 
          </td> 
          <td> Aptamer</td> 
          <td> A short single-stranded oligonucleotide that binds a specific target through its
             three-dimensional structure.</td> 
        </tr> 
        <tr> 
          <td style="white-space:nowrap">decoy
            <a name="oligo-nucleotide-type-decoy"> </a> 
          </td> 
          <td> Decoy oligonucleotide</td> 
          <td> An oligonucleotide that mimics a regulatory binding site to sequester a transcription
             factor or other binding protein.</td> 
        </tr> 
        <tr> 
          <td style="white-space:nowrap">ribozyme
            <a name="oligo-nucleotide-type-ribozyme"> </a> 
          </td> 
          <td> Ribozyme / DNAzyme</td> 
          <td> A catalytic oligonucleotide capable of cleaving a target nucleic acid.</td> 
        </tr> 
        <tr> 
          <td style="white-space:nowrap">gene-fragment
            <a name="oligo-nucleotide-type-gene-fragment"> </a> 
          </td> 
          <td> Gene fragment</td> 
          <td> A fragment of a gene such as a promoter, enhancer, coding region or silencer.</td> 
        </tr> 
      </table> 
    </div> 
  </text> 
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
    <valueCode value="brr"/> 
  </extension> 
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
    <valueCode value="informative"/> 
  </extension> 
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">
    <valueInteger value="1"/> 
  </extension> 
  <url value="http://hl7.org/fhir/oligo-nucleotide-type"/> 
  <version value="6.0.0-ballot4"/> 
  <name value="OligoNucleotideTypeExample"/> 
  <title value="Oligonucleotide Type"/> 
  <status value="active"/> 
  <experimental value="true"/> 
  <date value="2026-06-21"/> 
  <publisher value="HL7 (FHIR Project)"/> 
  <contact> 
    <telecom> 
      <system value="url"/> 
      <value value="http://hl7.org/fhir"/> 
    </telecom> 
    <telecom> 
      <system value="email"/> 
      <value value="fhir@lists.hl7.org"/> 
    </telecom> 
  </contact> 
  <description value="The class of oligonucleotide, where relevant (e.g. antisense, siRNA, aptamer)."/> 
  <jurisdiction> 
    <coding> 
      <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/> 
      <code value="001"/> 
      <display value="World"/> 
    </coding> 
  </jurisdiction> 
  <caseSensitive value="true"/> 
  <valueSet value="http://hl7.org/fhir/ValueSet/oligo-nucleotide-type"/> 
  <content value="complete"/> 
  <concept> 
    <code value="antisense"/> 
    <display value="Antisense oligonucleotide"/> 
    <definition value="An antisense oligonucleotide (ASO) that binds to a complementary mRNA sequence
     to inhibit gene expression."/> 
  </concept> 
  <concept> 
    <code value="sirna"/> 
    <display value="Small interfering RNA (siRNA)"/> 
    <definition value="A short double-stranded RNA that triggers degradation of a target mRNA through
     the RNA interference pathway."/> 
  </concept> 
  <concept> 
    <code value="mirna"/> 
    <display value="MicroRNA (miRNA)"/> 
    <definition value="A short non-coding RNA that regulates gene expression by base-pairing with target
     mRNAs."/> 
  </concept> 
  <concept> 
    <code value="aptamer"/> 
    <display value="Aptamer"/> 
    <definition value="A short single-stranded oligonucleotide that binds a specific target through its
     three-dimensional structure."/> 
  </concept> 
  <concept> 
    <code value="decoy"/> 
    <display value="Decoy oligonucleotide"/> 
    <definition value="An oligonucleotide that mimics a regulatory binding site to sequester a transcription
     factor or other binding protein."/> 
  </concept> 
  <concept> 
    <code value="ribozyme"/> 
    <display value="Ribozyme / DNAzyme"/> 
    <definition value="A catalytic oligonucleotide capable of cleaving a target nucleic acid."/> 
  </concept> 
  <concept> 
    <code value="gene-fragment"/> 
    <display value="Gene fragment"/> 
    <definition value="A fragment of a gene such as a promoter, enhancer, coding region or silencer."/> 
  </concept> 
</CodeSystem> 

Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.