IDEA4RC FHIR Implementation Guide, published by IDEA4RC Project. This guide is not an authorized publication; it is the continuous build for version 0.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/idea4rc/ and changes regularly. See the Directory of published versions

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• Detailed Descriptions
• Mappings
• XML
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• TTL

Logical Model: SubjectI4rc - XML Profile

XML representation of the Subject logical model.

Raw xml | Download

<StructureDefinition xmlns="http://hl7.org/fhir">
  <id value="Subject"/>
  <text>
    <status value="extensions"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: StructureDefinition Subject</b></p><a name="Subject"> </a><a name="hcSubject"> </a><a name="Subject-en-US"> </a><table border="0" cellpadding="0" cellspacing="0" style="border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;"><tr style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top"><th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="The logical name of the element">Name</a></th><th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Information about the use of the element">Flags</a></th><th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Minimum and Maximum # of times the element can appear in the instance">Card.</a></th><th style="width: 100px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Reference to the type of the element">Type</a></th><th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Additional information about the element">Description &amp; Constraints</a><span style="float: right"><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format"><img src="data:image/png;base64,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" alt="doco" style="background-color: inherit"/></a></span></th></tr><tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_element.gif" alt="." style="background-color: white; background-color: inherit" title="Element" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject" title="Subject of care.
Maturity Level: 0 Draft">Subject</a><a name="Subject"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="opacity: 0.5">0</span><span style="opacity: 0.5">..</span><span style="opacity: 0.5">*</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://build.fhir.org/types.html#Base">Base</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Patient</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.sex" title="Describes biological sex as recorded in the patient's identity document or in the hospital record. In the absence of documentation, the one declared by the patient will be recorded ">sex</a><a name="Subject.sex"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Sex (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.race" title="Describes race as recorded in  the hospital record, the one declared by the patient,, otherwise, the onerecognized by the observer 
privacy issues for registering race in France.

Hispanic is present only in BB. Hispanic is not mapped as race.

If Hispanic, OMOP race=0, if not, OMOP ethnicity=
38003564

If &quot;hispanic&quot; register ethnicity, otherwise register race">race</a><a name="Subject.race"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Race (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.birthYear" title="Year of birth of the patient. 
PERSON.year_of_birth">birthYear</a><a name="Subject.birthYear"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#integer">integer</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Birth year (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.countryOfResidence" title="Country of residence at the time of diagnosis ">countryOfResidence</a><a name="Subject.countryOfResidence"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Country of Residence (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.smoking" title="Describes tobacco smoker habits within the options proposed 
Changed vocabulary codes to be standard (BLUEBERRY was not)">smoking</a><a name="Subject.smoking"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Smoking (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.cigarettesPackYearsSmokedDuringLife" title="Calculates pack/ year by multiplying the number of packs of cigarettes smoked per day by the number of years the person has been smoking.

Register the actual value of pack/years in the value_as_number field">cigarettesPackYearsSmokedDuringLife</a><a name="Subject.cigarettesPackYearsSmokedDuringLife"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#integer">integer</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Cigarettes pack years smoked during life (R)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.alcohol" title="Describes alcohol habits within the options proposed ">alcohol</a><a name="Subject.alcohol"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Alcohol (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.bmi" title="Body Mass Index information if weight and height are included. it is calculated as BMI = kg/m2 where kg is a person's weight in kilograms and m2 is their height in metres squared. 
Register the actual value of BMI centile in the value_as_number field">bmi</a><a name="Subject.bmi"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#Quantity">Quantity</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Height/weight (BMI)
 (R)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.charlsonComorbidityIndex" title="Provides the Charlson Comorbidity index for the patient ">charlsonComorbidityIndex</a><a name="Subject.charlsonComorbidityIndex"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#integer">integer</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Charlson Comorbidity index (R)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity" title="Describes wherther the patient was diagnosed before treatment of at least one of the comorbidities listed or not. 
It refers to any disease or medical condition that is simultaneously present with the cancer under study. ">comorbidity</a><a name="Subject.comorbidity"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#BackboneElement">BackboneElement</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Comorbidity (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.myocardialInfarction" title="Describes comorbidities reported or assesed before treatment. More than one choice is allowed. Please do not include the current cancer in this calculation, only the previous cancer. ">myocardialInfarction</a><a name="Subject.comorbidity.myocardialInfarction"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Myocardial infarction (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.congestiveHeartFailure" title="Previous cancer comorbidity related to Congestive heart failure ">congestiveHeartFailure</a><a name="Subject.comorbidity.congestiveHeartFailure"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Congestive heart failure (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.peripheralVascularDisease" title="Previous cancer comorbidity related to Peripheral vascular disease ">peripheralVascularDisease</a><a name="Subject.comorbidity.peripheralVascularDisease"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Peripheral vascular disease (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia" title="Previous cancer comorbidity related to Cerebrovascular accident  (except hemiplegia) ">cerebrovascularAccidentExceptHemiplegia</a><a name="Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Cerebrovascular accident  (except hemiplegia) (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.dementia" title="Previous cancer comorbidity related to Dementia ">dementia</a><a name="Subject.comorbidity.dementia"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Dementia (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.chronicPulmonaryDisease" title="Previous cancer comorbidity related to Chronic pulmonary disease ">chronicPulmonaryDisease</a><a name="Subject.comorbidity.chronicPulmonaryDisease"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Chronic pulmonary disease (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.connectiveTissueDisease" title="Previous cancer comorbidity related to Connective tissue disease ">connectiveTissueDisease</a><a name="Subject.comorbidity.connectiveTissueDisease"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Connective tissue disease (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.ulcer" title="Previous cancer comorbidity related to Ulcer 
Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351">ulcer</a><a name="Subject.comorbidity.ulcer"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Ulcer (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.mildLiverDisease" title="Previous cancer comorbidity related to Mild liver disease ">mildLiverDisease</a><a name="Subject.comorbidity.mildLiverDisease"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mild liver disease (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.moderateToSevereLiverDisease" title="Previous cancer comorbidity related to Moderate to severe liver disease 
Same as Moderate to severe renal disease">moderateToSevereLiverDisease</a><a name="Subject.comorbidity.moderateToSevereLiverDisease"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Moderate to severe liver disease (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.diabetes" title="Previous cancer comorbidity related to Diabetes (without complications) ">diabetes</a><a name="Subject.comorbidity.diabetes"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Diabetes (without complications) (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.diabetesWithEndOrganDamage" title="Previous cancer comorbidity related to Diabetes with end organ damage ">diabetesWithEndOrganDamage</a><a name="Subject.comorbidity.diabetesWithEndOrganDamage"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Diabetes with end organ damage (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.hemiplegia" title="Previous cancer comorbidity related to Hemiplegia 
Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351">hemiplegia</a><a name="Subject.comorbidity.hemiplegia"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Hemiplegia (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.moderateToSevereRenalDisease" title="Previous cancer comorbidity related to Moderate to severe renal disease 
Same as Moderate to severe liver disease">moderateToSevereRenalDisease</a><a name="Subject.comorbidity.moderateToSevereRenalDisease"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Moderate to severe renal disease (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.solidTumor" title="Previous cancer comorbidity related to Solid tumor (non metastatic) 
History of event + Other cancer (find the corresponding standard concept)

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351

IT NEEDS TO BE PRESENTED">solidTumor</a><a name="Subject.comorbidity.solidTumor"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Solid tumor (non metastatic) (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.metastaticSolidTumor" title="Previous cancer comorbidity related to Metastatic solid tumor 
History of event + Other cancer (find the corresponding standard concept)">metastaticSolidTumor</a><a name="Subject.comorbidity.metastaticSolidTumor"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Metastatic solid tumor (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.leukemia" title="Previous cancer comorbidity related to Leukemia 
History of event + Leukemia

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351">leukemia</a><a name="Subject.comorbidity.leukemia"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Leukemia (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.lymphoma" title="Previous cancer comorbidity related to Lymphoma 
History of event + Malignant Lymphoma NOS

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351">lymphoma</a><a name="Subject.comorbidity.lymphoma"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Lymphoma (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.multipleMyeloma" title="Previous cancer comorbidity related to Multiple myeloma 
History of event + Multiple myeloma 

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351">multipleMyeloma</a><a name="Subject.comorbidity.multipleMyeloma"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Multiple myeloma (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.comorbidity.aids" title="Previous cancer comorbidity related to AIDS 
History of event + AIDS ">aids</a><a name="Subject.comorbidity.aids"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">AIDS (O)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.ecogPsAtDiagnosis" title="Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis ">ecogPsAtDiagnosis</a><a name="Subject.ecogPsAtDiagnosis"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#integer">integer</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis (R)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.ecogPsLabel" title="Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis ">ecogPsLabel</a><a name="Subject.ecogPsLabel"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">ECOG PS label (R)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.karnofsyIndexAtDiagnosis" title="Karnofsy index at diagnosis. Consider only the first KI before any treatment available in the clinical record. ">karnofsyIndexAtDiagnosis</a><a name="Subject.karnofsyIndexAtDiagnosis"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#integer">integer</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Karnofsy index at diagnosis (R)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.karnofsyIndexLabel" title="Karnofsy index at diagnosis. Consider only the first KI before any treatment available in the clinical record. ">karnofsyIndexLabel</a><a name="Subject.karnofsyIndexLabel"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Karnofsy index label (R)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020" title="If no genetic syndrome was identified for the patient. based on WHO 2020. 
use 37204336 [Genetic disease] as value_as_concept_id">noGeneticSyndromeWho2020</a><a name="Subject.noGeneticSyndromeWho2020"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">No Genetic syndrome (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.olliersDisease" title="If patient presents Olliers disease ">olliersDisease</a><a name="Subject.noGeneticSyndromeWho2020.olliersDisease"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Olliers disease (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.maffuciSyndrome" title="If patient presents Maffuci syndrome ">maffuciSyndrome</a><a name="Subject.noGeneticSyndromeWho2020.maffuciSyndrome"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Maffuci syndrome (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome" title="If patient presents Li-Fraumeni syndrome ">liFraumeniSyndrome</a><a name="Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Li-Fraumeni syndrome (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome" title="If patient presents McCune-Albright syndrome ">mcCuneAlbrightSyndrome</a><a name="Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">McCune-Albright syndrome (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.multipleOsteochondromas" title="If patient presents Multiple osteochondromas ">multipleOsteochondromas</a><a name="Subject.noGeneticSyndromeWho2020.multipleOsteochondromas"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Multiple osteochondromas (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.neurofibromatosisType1" title="If patient presents Neurofibromatosis type 1 ">neurofibromatosisType1</a><a name="Subject.noGeneticSyndromeWho2020.neurofibromatosisType1"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Neurofibromatosis type 1 (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome" title="If patient presents Rothmund-Thomson syndrome ">rothmundThomsonSyndrome</a><a name="Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Rothmund-Thomson syndrome (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.wernerSyndrome" title="If patient presents Werner syndrome ">wernerSyndrome</a><a name="Subject.noGeneticSyndromeWho2020.wernerSyndrome"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Werner syndrome (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.retinoblastoma" title="If patient presents Retinoblastoma ">retinoblastoma</a><a name="Subject.noGeneticSyndromeWho2020.retinoblastoma"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Retinoblastoma (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.pagetDisease" title="If patient presents Paget disease ">pagetDisease</a><a name="Subject.noGeneticSyndromeWho2020.pagetDisease"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#boolean">boolean</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Paget disease (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.otherSyndromes" title="If patient presents Other Genetic syndrome. According to WHO 2020 
History of event + 
Other genetic syndrome (find the corresponding standard concept)
If not specified, use 37204336 [Genetic disease]">otherSyndromes</a><a name="Subject.noGeneticSyndromeWho2020.otherSyndromes"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Other Genetic syndrome (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.previousMalignantCancerSite" title="Describes the site of the malignant tumour reported or assesed before the cancer under study. Any type of of solid and haematological cancer is listed. To obtain the previous malignant cancer refer to the solid tumor (metastatic and non-metastatic)  comorbidity 
History of event + 
Cancer modifier for site">previousMalignantCancerSite</a><a name="Subject.previousMalignantCancerSite"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Previous malignant cancer site (R)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-headneck-i4rc.html">Head and Neck</a></td></tr></table></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck00.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-Subject-definitions.html#Subject.previousCancerTreatment" title="Describes the type of treatment performed for the previous cancer 
History of event + 
Other treatment (find the corresponding standard concept)
If not specified,">previousCancerTreatment</a><a name="Subject.previousCancerTreatment"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="padding-left: 3px; padding-right: 3px; color: white; background-color: red" title="This element has obligations">O</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Previous cancer treatment (M)<br/><table class="grid"><tr><td style="font-size: 11px"><b>Obligations</b></td><td style="font-size: 11px"><b>Actor</b></td></tr><tr><td style="font-size: 11px"><b>SHALL</b>:<a href="http://hl7.org/fhir/extensions/5.2.0/CodeSystem-obligation.html#obligation-handle" title="Obligation Codes: correctly handle">handle</a></td><td style="font-size: 11px; opacity: 0.5;"><a href="ActorDefinition-actor-sarcoma-i4rc.html">Sarcoma</a></td></tr></table></td></tr>
<tr><td colspan="5" class="hierarchy"><br/><a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format"><img src="data:image/png;base64,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" alt="doco" style="background-color: inherit"/> Documentation for this format</a></td></tr></table></div>
  </text>
  <url value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject"/>
  <version value="0.1.0"/>
  <name value="SubjectI4rc"/>
  <title value="Patient"/>
  <status value="draft"/>
  <date value="2025-05-06T11:14:47+00:00"/>
  <publisher value="IDEA4RC Project"/>
  <contact>
    <name value="IDEA4RC Project"/>
    <telecom>
      <system value="url"/>
      <value value="https://www.idea4rc.eu/"/>
    </telecom>
  </contact>
  <contact>
    <name value="IDEA4RC Project"/>
    <telecom>
      <system value="url"/>
      <value value="https://www.idea4rc.eu/"/>
    </telecom>
  </contact>
  <description value="Subject of care.
Maturity Level: 0 Draft"/>
  <jurisdiction>
    <coding>
      <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
      <code value="150"/>
      <display value="Europe"/>
    </coding>
  </jurisdiction>
  <fhirVersion value="4.0.1"/>
  <kind value="logical"/>
  <abstract value="false"/>
  <type value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject"/>
  <baseDefinition value="http://hl7.org/fhir/StructureDefinition/Base"/>
  <derivation value="specialization"/>
  <snapshot>
    <extension
               url="http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version">
      <valueString value="4.0.1"/>
    </extension>
    <element id="Subject">
      <path value="Subject"/>
      <short value="Patient"/>
      <definition value="Subject of care.
Maturity Level: 0 Draft"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Base"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <isModifier value="false"/>
    </element>
    <element id="Subject.sex">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.sex"/>
      <short value="Sex (M)"/>
      <definition
                  value="Describes biological sex as recorded in the patient's identity document or in the hospital record. In the absence of documentation, the one declared by the patient will be recorded"/>
      <comment value="Male - 8507
Female - 8532"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.sex"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.race">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.race"/>
      <short value="Race (M)"/>
      <definition
                  value="Describes race as recorded in  the hospital record, the one declared by the patient,, otherwise, the onerecognized by the observer 
privacy issues for registering race in France.

Hispanic is present only in BB. Hispanic is not mapped as race.

If Hispanic, OMOP race=0, if not, OMOP ethnicity=
38003564

If &quot;hispanic&quot; register ethnicity, otherwise register race"/>
      <comment
               value="White - 8527
Black - 8516
Asian/Pacific Islanders - 8515
American Indian/Alaska Native - 8657
        Hispanic or Latino - 38003563"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.race"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.birthYear">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.birthYear"/>
      <short value="Birth year (M)"/>
      <definition
                  value="Year of birth of the patient. 
PERSON.year_of_birth"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.birthYear"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="integer"/>
      </type>
    </element>
    <element id="Subject.countryOfResidence">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.countryOfResidence"/>
      <short value="Country of Residence (M)"/>
      <definition value="Country of residence at the time of diagnosis"/>
      <comment value="Son in the hierarchy of countries"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.countryOfResidence"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.smoking">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.smoking"/>
      <short value="Smoking (M)"/>
      <definition
                  value="Describes tobacco smoker habits within the options proposed 
Changed vocabulary codes to be standard (BLUEBERRY was not)"/>
      <comment
               value="Current smoker - 36309332
Former smoker - 45883458
Never smoker - 45879404"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.smoking"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.cigarettesPackYearsSmokedDuringLife">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.cigarettesPackYearsSmokedDuringLife"/>
      <short value="Cigarettes pack years smoked during life (R)"/>
      <definition
                  value="Calculates pack/ year by multiplying the number of packs of cigarettes smoked per day by the number of years the person has been smoking.

Register the actual value of pack/years in the value_as_number field"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.cigarettesPackYearsSmokedDuringLife"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="integer"/>
      </type>
    </element>
    <element id="Subject.alcohol">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.alcohol"/>
      <short value="Alcohol (M)"/>
      <definition
                  value="Describes alcohol habits within the options proposed"/>
      <comment
               value="Current drinker - 4074035
Ex-drinker - 4220362
Lifetime non-drinker of alcohol - 37204556
Ex-problem drinker - 4117706"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.alcohol"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.bmi">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.bmi"/>
      <short value="Height/weight (BMI)
 (R)"/>
      <definition
                  value="Body Mass Index information if weight and height are included. it is calculated as BMI = kg/m2 where kg is a person's weight in kilograms and m2 is their height in metres squared. 
Register the actual value of BMI centile in the value_as_number field"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.bmi"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Quantity"/>
      </type>
    </element>
    <element id="Subject.charlsonComorbidityIndex">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.charlsonComorbidityIndex"/>
      <short value="Charlson Comorbidity index (R)"/>
      <definition
                  value="Provides the Charlson Comorbidity index for the patient"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.charlsonComorbidityIndex"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="integer"/>
      </type>
    </element>
    <element id="Subject.comorbidity">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity"/>
      <short value="Comorbidity (M)"/>
      <definition
                  value="Describes wherther the patient was diagnosed before treatment of at least one of the comorbidities listed or not. 
It refers to any disease or medical condition that is simultaneously present with the cancer under study."/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="BackboneElement"/>
      </type>
      <constraint>
        <key value="ele-1"/>
        <severity value="error"/>
        <human value="All FHIR elements must have a @value or children"/>
        <expression
                    value="hasValue() or (children().count() &gt; id.count())"/>
        <xpath value="@value|f:*|h:div"/>
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
      </constraint>
    </element>
    <element id="Subject.comorbidity.id">
      <path value="Subject.comorbidity.id"/>
      <representation value="xmlAttr"/>
      <short value="Unique id for inter-element referencing"/>
      <definition
                  value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces."/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="Element.id"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <extension
                   url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="string"/>
        </extension>
        <code value="http://hl7.org/fhirpath/System.String"/>
      </type>
      <isModifier value="false"/>
      <isSummary value="false"/>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element id="Subject.comorbidity.extension">
      <path value="Subject.comorbidity.extension"/>
      <slicing>
        <discriminator>
          <type value="value"/>
          <path value="url"/>
        </discriminator>
        <description value="Extensions are always sliced by (at least) url"/>
        <rules value="open"/>
      </slicing>
      <short value="Additional content defined by implementations"/>
      <definition
                  value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension."/>
      <comment
               value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Element.extension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <constraint>
        <key value="ele-1"/>
        <severity value="error"/>
        <human value="All FHIR elements must have a @value or children"/>
        <expression
                    value="hasValue() or (children().count() &gt; id.count())"/>
        <xpath value="@value|f:*|h:div"/>
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
      </constraint>
      <constraint>
        <key value="ext-1"/>
        <severity value="error"/>
        <human value="Must have either extensions or value[x], not both"/>
        <expression value="extension.exists() != value.exists()"/>
        <xpath
               value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/>
        <source value="http://hl7.org/fhir/StructureDefinition/Extension"/>
      </constraint>
      <isModifier value="false"/>
      <isSummary value="false"/>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element id="Subject.comorbidity.modifierExtension">
      <path value="Subject.comorbidity.modifierExtension"/>
      <short value="Extensions that cannot be ignored even if unrecognized"/>
      <definition
                  value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)."/>
      <comment
               value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <requirements
                    value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <alias value="modifiers"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="BackboneElement.modifierExtension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <constraint>
        <key value="ele-1"/>
        <severity value="error"/>
        <human value="All FHIR elements must have a @value or children"/>
        <expression
                    value="hasValue() or (children().count() &gt; id.count())"/>
        <xpath value="@value|f:*|h:div"/>
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
      </constraint>
      <constraint>
        <key value="ext-1"/>
        <severity value="error"/>
        <human value="Must have either extensions or value[x], not both"/>
        <expression value="extension.exists() != value.exists()"/>
        <xpath
               value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/>
        <source value="http://hl7.org/fhir/StructureDefinition/Extension"/>
      </constraint>
      <isModifier value="true"/>
      <isModifierReason
                        value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them"/>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element id="Subject.comorbidity.myocardialInfarction">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.myocardialInfarction"/>
      <short value="Myocardial infarction (O)"/>
      <definition
                  value="Describes comorbidities reported or assesed before treatment. More than one choice is allowed. Please do not include the current cancer in this calculation, only the previous cancer."/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.myocardialInfarction"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.congestiveHeartFailure">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.congestiveHeartFailure"/>
      <short value="Congestive heart failure (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Congestive heart failure"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.congestiveHeartFailure"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.peripheralVascularDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.peripheralVascularDisease"/>
      <short value="Peripheral vascular disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Peripheral vascular disease"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.peripheralVascularDisease"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element
             id="Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path
            value="Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia"/>
      <short value="Cerebrovascular accident  (except hemiplegia) (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Cerebrovascular accident  (except hemiplegia)"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path
              value="Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.dementia">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.dementia"/>
      <short value="Dementia (O)"/>
      <definition value="Previous cancer comorbidity related to Dementia"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.dementia"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.chronicPulmonaryDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.chronicPulmonaryDisease"/>
      <short value="Chronic pulmonary disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Chronic pulmonary disease"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.chronicPulmonaryDisease"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.connectiveTissueDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.connectiveTissueDisease"/>
      <short value="Connective tissue disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Connective tissue disease"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.connectiveTissueDisease"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.ulcer">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.ulcer"/>
      <short value="Ulcer (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Ulcer 
Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.ulcer"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.mildLiverDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.mildLiverDisease"/>
      <short value="Mild liver disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Mild liver disease"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.mildLiverDisease"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.moderateToSevereLiverDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.moderateToSevereLiverDisease"/>
      <short value="Moderate to severe liver disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Moderate to severe liver disease 
Same as Moderate to severe renal disease"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.moderateToSevereLiverDisease"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.diabetes">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.diabetes"/>
      <short value="Diabetes (without complications) (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Diabetes (without complications)"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.diabetes"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.diabetesWithEndOrganDamage">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.diabetesWithEndOrganDamage"/>
      <short value="Diabetes with end organ damage (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Diabetes with end organ damage"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.diabetesWithEndOrganDamage"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.hemiplegia">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.hemiplegia"/>
      <short value="Hemiplegia (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Hemiplegia 
Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.hemiplegia"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.moderateToSevereRenalDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.moderateToSevereRenalDisease"/>
      <short value="Moderate to severe renal disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Moderate to severe renal disease 
Same as Moderate to severe liver disease"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.moderateToSevereRenalDisease"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.solidTumor">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.solidTumor"/>
      <short value="Solid tumor (non metastatic) (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Solid tumor (non metastatic) 
History of event + Other cancer (find the corresponding standard concept)

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351

IT NEEDS TO BE PRESENTED"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.solidTumor"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.metastaticSolidTumor">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.metastaticSolidTumor"/>
      <short value="Metastatic solid tumor (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Metastatic solid tumor 
History of event + Other cancer (find the corresponding standard concept)"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.metastaticSolidTumor"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.leukemia">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.leukemia"/>
      <short value="Leukemia (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Leukemia 
History of event + Leukemia

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.leukemia"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.lymphoma">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.lymphoma"/>
      <short value="Lymphoma (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Lymphoma 
History of event + Malignant Lymphoma NOS

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.lymphoma"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.multipleMyeloma">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.multipleMyeloma"/>
      <short value="Multiple myeloma (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Multiple myeloma 
History of event + Multiple myeloma 

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.multipleMyeloma"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.aids">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.aids"/>
      <short value="AIDS (O)"/>
      <definition
                  value="Previous cancer comorbidity related to AIDS 
History of event + AIDS"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.comorbidity.aids"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.ecogPsAtDiagnosis">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.ecogPsAtDiagnosis"/>
      <short
             value="Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis (R)"/>
      <definition
                  value="Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.ecogPsAtDiagnosis"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="integer"/>
      </type>
    </element>
    <element id="Subject.ecogPsLabel">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.ecogPsLabel"/>
      <short value="ECOG PS label (R)"/>
      <definition
                  value="Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis"/>
      <comment
               value="Answers of ECOG Performance Status [Interpretation] - 36303470"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.ecogPsLabel"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.karnofsyIndexAtDiagnosis">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.karnofsyIndexAtDiagnosis"/>
      <short value="Karnofsy index at diagnosis (R)"/>
      <definition
                  value="Karnofsy index at diagnosis. Consider only the first KI before any treatment available in the clinical record."/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.karnofsyIndexAtDiagnosis"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="integer"/>
      </type>
    </element>
    <element id="Subject.karnofsyIndexLabel">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.karnofsyIndexLabel"/>
      <short value="Karnofsy index label (R)"/>
      <definition
                  value="Karnofsy index at diagnosis. Consider only the first KI before any treatment available in the clinical record."/>
      <comment
               value="Answers of Karnofsky Performance Status [Interpretation] - 36303744"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.karnofsyIndexLabel"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020"/>
      <short value="No Genetic syndrome (M)"/>
      <definition
                  value="If no genetic syndrome was identified for the patient. based on WHO 2020. 
use 37204336 [Genetic disease] as value_as_concept_id"/>
      <comment value="No evidence of - 4211787"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.noGeneticSyndromeWho2020"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
      <constraint>
        <key value="ele-1"/>
        <severity value="error"/>
        <human value="All FHIR elements must have a @value or children"/>
        <expression
                    value="hasValue() or (children().count() &gt; id.count())"/>
        <xpath value="@value|f:*|h:div"/>
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
      </constraint>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.id">
      <path value="Subject.noGeneticSyndromeWho2020.id"/>
      <representation value="xmlAttr"/>
      <short value="xml:id (or equivalent in JSON)"/>
      <definition
                  value="unique id for the element within a resource (for internal references)"/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="Element.id"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <extension
                   url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="string"/>
        </extension>
        <code value="http://hl7.org/fhirpath/System.String"/>
      </type>
      <isModifier value="false"/>
      <isSummary value="false"/>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.extension">
      <path value="Subject.noGeneticSyndromeWho2020.extension"/>
      <short value="Additional content defined by implementations"/>
      <definition
                  value="May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension."/>
      <comment
               value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Element.extension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <constraint>
        <key value="ele-1"/>
        <severity value="error"/>
        <human value="All FHIR elements must have a @value or children"/>
        <expression
                    value="hasValue() or (children().count() &gt; id.count())"/>
        <xpath value="@value|f:*|h:div"/>
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/>
      </constraint>
      <constraint>
        <key value="ext-1"/>
        <severity value="error"/>
        <human value="Must have either extensions or value[x], not both"/>
        <expression value="extension.exists() != value.exists()"/>
        <xpath
               value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])"/>
        <source value="http://hl7.org/fhir/StructureDefinition/Extension"/>
      </constraint>
      <isModifier value="false"/>
      <isSummary value="false"/>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.value">
      <path value="Subject.noGeneticSyndromeWho2020.value"/>
      <representation value="xmlAttr"/>
      <short value="Primitive value for boolean"/>
      <definition value="The actual value"/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="boolean.value"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <extension
                   url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="boolean"/>
        </extension>
        <extension url="http://hl7.org/fhir/StructureDefinition/regex">
          <valueString value="true|false"/>
        </extension>
        <code value="http://hl7.org/fhirpath/System.Boolean"/>
      </type>
      <isModifier value="false"/>
      <isSummary value="false"/>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.olliersDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.olliersDisease"/>
      <short value="Olliers disease (M)"/>
      <definition value="If patient presents Olliers disease"/>
      <comment value="Enchondromatosis - 4145177"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.noGeneticSyndromeWho2020.olliersDisease"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.maffuciSyndrome">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.maffuciSyndrome"/>
      <short value="Maffuci syndrome (M)"/>
      <definition value="If patient presents Maffuci syndrome"/>
      <comment value="Maffucci syndrome - 4187683"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.noGeneticSyndromeWho2020.maffuciSyndrome"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome"/>
      <short value="Li-Fraumeni syndrome (M)"/>
      <definition value="If patient presents Li-Fraumeni syndrome"/>
      <comment value="Li-Fraumeni syndrome - 4323645"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome"/>
      <short value="McCune-Albright syndrome (M)"/>
      <definition value="If patient presents McCune-Albright syndrome"/>
      <comment value="McCune Albright syndrome - 37117262"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path
              value="Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.multipleOsteochondromas">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.multipleOsteochondromas"/>
      <short value="Multiple osteochondromas (M)"/>
      <definition value="If patient presents Multiple osteochondromas"/>
      <comment value="Multiple osteochondroma - 37396802"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path
              value="Subject.noGeneticSyndromeWho2020.multipleOsteochondromas"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.neurofibromatosisType1">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.neurofibromatosisType1"/>
      <short value="Neurofibromatosis type 1 (M)"/>
      <definition value="If patient presents Neurofibromatosis type 1"/>
      <comment value="Neurofibromatosis type 1 - 377252"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path
              value="Subject.noGeneticSyndromeWho2020.neurofibromatosisType1"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome"/>
      <short value="Rothmund-Thomson syndrome (M)"/>
      <definition value="If patient presents Rothmund-Thomson syndrome"/>
      <comment value="Rothmund-Thomson syndrome - 4286355"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path
              value="Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.wernerSyndrome">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.wernerSyndrome"/>
      <short value="Werner syndrome (M)"/>
      <definition value="If patient presents Werner syndrome"/>
      <comment value="Werner syndrome - 4197821"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.noGeneticSyndromeWho2020.wernerSyndrome"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.retinoblastoma">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.retinoblastoma"/>
      <short value="Retinoblastoma (M)"/>
      <definition value="If patient presents Retinoblastoma"/>
      <comment value="Retinoblastoma - 4158977"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.noGeneticSyndromeWho2020.retinoblastoma"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.pagetDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.pagetDisease"/>
      <short value="Paget disease (M)"/>
      <definition value="If patient presents Paget disease"/>
      <comment value="Osteitis deformans - 75910"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.noGeneticSyndromeWho2020.pagetDisease"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.otherSyndromes">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.otherSyndromes"/>
      <short value="Other Genetic syndrome (M)"/>
      <definition
                  value="If patient presents Other Genetic syndrome. According to WHO 2020 
History of event + 
Other genetic syndrome (find the corresponding standard concept)
If not specified, use 37204336 [Genetic disease]"/>
      <comment
               value="History of event - 1340204

+ Any Standard Condition Code
If not specified, use 37204336 [Genetic disease]"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.noGeneticSyndromeWho2020.otherSyndromes"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.previousMalignantCancerSite">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.previousMalignantCancerSite"/>
      <short value="Previous malignant cancer site (R)"/>
      <definition
                  value="Describes the site of the malignant tumour reported or assesed before the cancer under study. Any type of of solid and haematological cancer is listed. To obtain the previous malignant cancer refer to the solid tumor (metastatic and non-metastatic)  comorbidity 
History of event + 
Cancer modifier for site"/>
      <comment
               value="Values from CancerModifier Topography

Use integer for IDEA4RC if needed"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Subject.previousMalignantCancerSite"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.previousCancerTreatment">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
        <extension url="source">
          <valueUri
                    value="http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject|0.1.0"/>
        </extension>
      </extension>
      <path value="Subject.previousCancerTreatment"/>
      <short value="Previous cancer treatment (M)"/>
      <definition
                  value="Describes the type of treatment performed for the previous cancer 
History of event + 
Other treatment (find the corresponding standard concept)
If not specified,"/>
      <comment
               value="Chemotherapy - 4273629
Radiation oncology- 4170755
Surgery - 4121697 
Comprehensive medication therapy review - 42535584
Immunological therapy - 4295112"/>
      <min value="1"/>
      <max value="*"/>
      <base>
        <path value="Subject.previousCancerTreatment"/>
        <min value="1"/>
        <max value="*"/>
      </base>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
  </snapshot>
  <differential>
    <element id="Subject">
      <path value="Subject"/>
      <short value="Patient"/>
      <definition value="Subject of care.
Maturity Level: 0 Draft"/>
    </element>
    <element id="Subject.sex">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.sex"/>
      <short value="Sex (M)"/>
      <definition
                  value="Describes biological sex as recorded in the patient's identity document or in the hospital record. In the absence of documentation, the one declared by the patient will be recorded "/>
      <comment value="Male - 8507
Female - 8532"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.race">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.race"/>
      <short value="Race (M)"/>
      <definition
                  value="Describes race as recorded in  the hospital record, the one declared by the patient,, otherwise, the onerecognized by the observer 
privacy issues for registering race in France.

Hispanic is present only in BB. Hispanic is not mapped as race.

If Hispanic, OMOP race=0, if not, OMOP ethnicity=
38003564

If &quot;hispanic&quot; register ethnicity, otherwise register race"/>
      <comment
               value="White - 8527
Black - 8516
Asian/Pacific Islanders - 8515
American Indian/Alaska Native - 8657
        Hispanic or Latino - 38003563"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.birthYear">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.birthYear"/>
      <short value="Birth year (M)"/>
      <definition
                  value="Year of birth of the patient. 
PERSON.year_of_birth"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="integer"/>
      </type>
    </element>
    <element id="Subject.countryOfResidence">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.countryOfResidence"/>
      <short value="Country of Residence (M)"/>
      <definition value="Country of residence at the time of diagnosis "/>
      <comment value="Son in the hierarchy of countries"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.smoking">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.smoking"/>
      <short value="Smoking (M)"/>
      <definition
                  value="Describes tobacco smoker habits within the options proposed 
Changed vocabulary codes to be standard (BLUEBERRY was not)"/>
      <comment
               value="Current smoker - 36309332
Former smoker - 45883458
Never smoker - 45879404"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.cigarettesPackYearsSmokedDuringLife">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.cigarettesPackYearsSmokedDuringLife"/>
      <short value="Cigarettes pack years smoked during life (R)"/>
      <definition
                  value="Calculates pack/ year by multiplying the number of packs of cigarettes smoked per day by the number of years the person has been smoking.

Register the actual value of pack/years in the value_as_number field"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="integer"/>
      </type>
    </element>
    <element id="Subject.alcohol">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.alcohol"/>
      <short value="Alcohol (M)"/>
      <definition
                  value="Describes alcohol habits within the options proposed "/>
      <comment
               value="Current drinker - 4074035
Ex-drinker - 4220362
Lifetime non-drinker of alcohol - 37204556
Ex-problem drinker - 4117706"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.bmi">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.bmi"/>
      <short value="Height/weight (BMI)
 (R)"/>
      <definition
                  value="Body Mass Index information if weight and height are included. it is calculated as BMI = kg/m2 where kg is a person's weight in kilograms and m2 is their height in metres squared. 
Register the actual value of BMI centile in the value_as_number field"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Quantity"/>
      </type>
    </element>
    <element id="Subject.charlsonComorbidityIndex">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.charlsonComorbidityIndex"/>
      <short value="Charlson Comorbidity index (R)"/>
      <definition
                  value="Provides the Charlson Comorbidity index for the patient "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="integer"/>
      </type>
    </element>
    <element id="Subject.comorbidity">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity"/>
      <short value="Comorbidity (M)"/>
      <definition
                  value="Describes wherther the patient was diagnosed before treatment of at least one of the comorbidities listed or not. 
It refers to any disease or medical condition that is simultaneously present with the cancer under study. "/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="BackboneElement"/>
      </type>
    </element>
    <element id="Subject.comorbidity.myocardialInfarction">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.myocardialInfarction"/>
      <short value="Myocardial infarction (O)"/>
      <definition
                  value="Describes comorbidities reported or assesed before treatment. More than one choice is allowed. Please do not include the current cancer in this calculation, only the previous cancer. "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.congestiveHeartFailure">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.congestiveHeartFailure"/>
      <short value="Congestive heart failure (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Congestive heart failure "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.peripheralVascularDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.peripheralVascularDisease"/>
      <short value="Peripheral vascular disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Peripheral vascular disease "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element
             id="Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path
            value="Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia"/>
      <short value="Cerebrovascular accident  (except hemiplegia) (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Cerebrovascular accident  (except hemiplegia) "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.dementia">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.dementia"/>
      <short value="Dementia (O)"/>
      <definition value="Previous cancer comorbidity related to Dementia "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.chronicPulmonaryDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.chronicPulmonaryDisease"/>
      <short value="Chronic pulmonary disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Chronic pulmonary disease "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.connectiveTissueDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.connectiveTissueDisease"/>
      <short value="Connective tissue disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Connective tissue disease "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.ulcer">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.ulcer"/>
      <short value="Ulcer (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Ulcer 
Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.mildLiverDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.mildLiverDisease"/>
      <short value="Mild liver disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Mild liver disease "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.moderateToSevereLiverDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.moderateToSevereLiverDisease"/>
      <short value="Moderate to severe liver disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Moderate to severe liver disease 
Same as Moderate to severe renal disease"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.diabetes">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.diabetes"/>
      <short value="Diabetes (without complications) (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Diabetes (without complications) "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.diabetesWithEndOrganDamage">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.diabetesWithEndOrganDamage"/>
      <short value="Diabetes with end organ damage (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Diabetes with end organ damage "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.hemiplegia">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.hemiplegia"/>
      <short value="Hemiplegia (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Hemiplegia 
Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.moderateToSevereRenalDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.moderateToSevereRenalDisease"/>
      <short value="Moderate to severe renal disease (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Moderate to severe renal disease 
Same as Moderate to severe liver disease"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.solidTumor">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.solidTumor"/>
      <short value="Solid tumor (non metastatic) (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Solid tumor (non metastatic) 
History of event + Other cancer (find the corresponding standard concept)

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351

IT NEEDS TO BE PRESENTED"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.metastaticSolidTumor">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.metastaticSolidTumor"/>
      <short value="Metastatic solid tumor (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Metastatic solid tumor 
History of event + Other cancer (find the corresponding standard concept)"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.leukemia">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.leukemia"/>
      <short value="Leukemia (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Leukemia 
History of event + Leukemia

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.lymphoma">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.lymphoma"/>
      <short value="Lymphoma (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Lymphoma 
History of event + Malignant Lymphoma NOS

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.multipleMyeloma">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.multipleMyeloma"/>
      <short value="Multiple myeloma (O)"/>
      <definition
                  value="Previous cancer comorbidity related to Multiple myeloma 
History of event + Multiple myeloma 

Couldnt find it under https://athena.ohdsi.org/search-terms/terms/46235351"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.comorbidity.aids">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.comorbidity.aids"/>
      <short value="AIDS (O)"/>
      <definition
                  value="Previous cancer comorbidity related to AIDS 
History of event + AIDS "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.ecogPsAtDiagnosis">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.ecogPsAtDiagnosis"/>
      <short
             value="Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis (R)"/>
      <definition
                  value="Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="integer"/>
      </type>
    </element>
    <element id="Subject.ecogPsLabel">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.ecogPsLabel"/>
      <short value="ECOG PS label (R)"/>
      <definition
                  value="Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis "/>
      <comment
               value="Answers of ECOG Performance Status [Interpretation] - 36303470"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.karnofsyIndexAtDiagnosis">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.karnofsyIndexAtDiagnosis"/>
      <short value="Karnofsy index at diagnosis (R)"/>
      <definition
                  value="Karnofsy index at diagnosis. Consider only the first KI before any treatment available in the clinical record. "/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="integer"/>
      </type>
    </element>
    <element id="Subject.karnofsyIndexLabel">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.karnofsyIndexLabel"/>
      <short value="Karnofsy index label (R)"/>
      <definition
                  value="Karnofsy index at diagnosis. Consider only the first KI before any treatment available in the clinical record. "/>
      <comment
               value="Answers of Karnofsky Performance Status [Interpretation] - 36303744"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020"/>
      <short value="No Genetic syndrome (M)"/>
      <definition
                  value="If no genetic syndrome was identified for the patient. based on WHO 2020. 
use 37204336 [Genetic disease] as value_as_concept_id"/>
      <comment value="No evidence of - 4211787"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.olliersDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.olliersDisease"/>
      <short value="Olliers disease (M)"/>
      <definition value="If patient presents Olliers disease "/>
      <comment value="Enchondromatosis - 4145177"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.maffuciSyndrome">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.maffuciSyndrome"/>
      <short value="Maffuci syndrome (M)"/>
      <definition value="If patient presents Maffuci syndrome "/>
      <comment value="Maffucci syndrome - 4187683"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome"/>
      <short value="Li-Fraumeni syndrome (M)"/>
      <definition value="If patient presents Li-Fraumeni syndrome "/>
      <comment value="Li-Fraumeni syndrome - 4323645"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome"/>
      <short value="McCune-Albright syndrome (M)"/>
      <definition value="If patient presents McCune-Albright syndrome "/>
      <comment value="McCune Albright syndrome - 37117262"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.multipleOsteochondromas">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.multipleOsteochondromas"/>
      <short value="Multiple osteochondromas (M)"/>
      <definition value="If patient presents Multiple osteochondromas "/>
      <comment value="Multiple osteochondroma - 37396802"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.neurofibromatosisType1">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.neurofibromatosisType1"/>
      <short value="Neurofibromatosis type 1 (M)"/>
      <definition value="If patient presents Neurofibromatosis type 1 "/>
      <comment value="Neurofibromatosis type 1 - 377252"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome"/>
      <short value="Rothmund-Thomson syndrome (M)"/>
      <definition value="If patient presents Rothmund-Thomson syndrome "/>
      <comment value="Rothmund-Thomson syndrome - 4286355"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.wernerSyndrome">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.wernerSyndrome"/>
      <short value="Werner syndrome (M)"/>
      <definition value="If patient presents Werner syndrome "/>
      <comment value="Werner syndrome - 4197821"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.retinoblastoma">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.retinoblastoma"/>
      <short value="Retinoblastoma (M)"/>
      <definition value="If patient presents Retinoblastoma "/>
      <comment value="Retinoblastoma - 4158977"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.pagetDisease">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.pagetDisease"/>
      <short value="Paget disease (M)"/>
      <definition value="If patient presents Paget disease "/>
      <comment value="Osteitis deformans - 75910"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="boolean"/>
      </type>
    </element>
    <element id="Subject.noGeneticSyndromeWho2020.otherSyndromes">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.noGeneticSyndromeWho2020.otherSyndromes"/>
      <short value="Other Genetic syndrome (M)"/>
      <definition
                  value="If patient presents Other Genetic syndrome. According to WHO 2020 
History of event + 
Other genetic syndrome (find the corresponding standard concept)
If not specified, use 37204336 [Genetic disease]"/>
      <comment
               value="History of event - 1340204

+ Any Standard Condition Code
If not specified, use 37204336 [Genetic disease]"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.previousMalignantCancerSite">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.previousMalignantCancerSite"/>
      <short value="Previous malignant cancer site (R)"/>
      <definition
                  value="Describes the site of the malignant tumour reported or assesed before the cancer under study. Any type of of solid and haematological cancer is listed. To obtain the previous malignant cancer refer to the solid tumor (metastatic and non-metastatic)  comorbidity 
History of event + 
Cancer modifier for site"/>
      <comment
               value="Values from CancerModifier Topography

Use integer for IDEA4RC if needed"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
    <element id="Subject.previousCancerTreatment">
      <extension url="http://hl7.org/fhir/StructureDefinition/obligation">
        <extension url="code">
          <valueCode value="SHALL:handle"/>
        </extension>
        <extension url="actor">
          <valueCanonical
                          value="http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"/>
        </extension>
      </extension>
      <path value="Subject.previousCancerTreatment"/>
      <short value="Previous cancer treatment (M)"/>
      <definition
                  value="Describes the type of treatment performed for the previous cancer 
History of event + 
Other treatment (find the corresponding standard concept)
If not specified,"/>
      <comment
               value="Chemotherapy - 4273629
Radiation oncology- 4170755
Surgery - 4121697 
Comprehensive medication therapy review - 42535584
Immunological therapy - 4295112"/>
      <min value="1"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
    </element>
  </differential>
</StructureDefinition>