Patient - JSON Representation - IDEA4RC FHIR Implementation Guide v0.1.0

IDEA4RC FHIR Implementation Guide, published by IDEA4RC Project. This guide is not an authorized publication; it is the continuous build for version 0.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/idea4rc/ and changes regularly. See the Directory of published versions
Logical Model: SubjectI4rc - JSON Profile

Draft as of 2024-11-12
JSON representation of the Subject logical model.
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{
  "resourceType" : "StructureDefinition",
  "id" : "Subject",
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: StructureDefinition Subject</b></p><a name=\"Subject\"> </a><a name=\"hcSubject\"> </a><a name=\"Subject-en-US\"> </a><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top\"><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"The logical name of the element\">Name</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Information about the use of the element\">Flags</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Minimum and Maximum # of times the element can appear in the instance\">Card.</a></th><th style=\"width: 100px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Reference to the type of the element\">Type</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Additional information about the element\">Description &amp; Constraints</a><span style=\"float: right\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject\" title=\"Subject of care \nMaturity Level: 0 Draft\">Subject</a><a name=\"Subject\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">*</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://build.fhir.org/types.html#Base\">Base</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Subject of care<br/><span style=\"font-weight:bold\">Instances of this logical model are not marked to be the target of a Reference</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.sex\" title=\"Describes biological sex as recorded in the patient's identity document or in the hospital record. In the absence of documentation, the one declared by the patient will be recorded\">sex</a><a name=\"Subject.sex\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Gender<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.race\" title=\"Describes race as recorded in  the hospital record, the one declared by the patient,, otherwise, the onerecognized by the observer\">race</a><a name=\"Subject.race\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Race<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.birthYear\" title=\"Year of birth of the patient.\">birthYear</a><a name=\"Subject.birthYear\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Birth year<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.countryOfResidence\" title=\"Country of residence at the time of diagnosis\">countryOfResidence</a><a name=\"Subject.countryOfResidence\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Country of Residence<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.smoking\" title=\"Describes tobacco smoker habits within the options proposed\">smoking</a><a name=\"Subject.smoking\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Smoking<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.cigarettesPackYearsSmokedDuringLife\" title=\"The amount of cigarette pack smoked during life\">cigarettesPackYearsSmokedDuringLife</a><a name=\"Subject.cigarettesPackYearsSmokedDuringLife\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Cigarettes pack years smoked during life<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.alcohol\" title=\"Describes alcohol habits within the options proposed\">alcohol</a><a name=\"Subject.alcohol\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Alcohol<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.bMI\" title=\"Body Mass Index information if weight and height are included. it is calculated as BMI = kg/m2 where kg is a person's weight in kilograms and m2 is their height in metres squared.\">bMI</a><a name=\"Subject.bMI\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Quantity\">Quantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Height/weight (BMI)<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.charlsonComorbidityIndex\" title=\"Provides the Charlson Comorbidity index for the patient\">charlsonComorbidityIndex</a><a name=\"Subject.charlsonComorbidityIndex\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Charlson Comorbidity index<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity\" title=\"Describes whether the patient was diagnosed before treatment of at least one of the comorbidities listed  next (or not) relevant for head and neck cancer.\">comorbidity</a><a name=\"Subject.comorbidity\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Comorbidity<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.myocardialInfarction\" title=\"Describes comorbidities reported or assesed before treatment. More than one choice is allowed. Please do not include the current cancer in this calculation, only the previous cancer.\">myocardialInfarction</a><a name=\"Subject.comorbidity.myocardialInfarction\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Myocardial infarction<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.congestiveHeartFailure\" title=\"Previous cancer comorbidity related to Congestive heart failure\">congestiveHeartFailure</a><a name=\"Subject.comorbidity.congestiveHeartFailure\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Congestive heart failure<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.peripheralVascularDisease\" title=\"Previous cancer comorbidity related to Peripheral vascular disease\">peripheralVascularDisease</a><a name=\"Subject.comorbidity.peripheralVascularDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Peripheral vascular disease<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia\" title=\"Previous cancer comorbidity related to Cerebrovascular accident  (except hemiplegia)\">cerebrovascularAccidentExceptHemiplegia</a><a name=\"Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Cerebrovascular accident  (except hemiplegia)<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.dementia\" title=\"Previous cancer comorbidity related to Dementia\">dementia</a><a name=\"Subject.comorbidity.dementia\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Dementia<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.chronicPulmonaryDisease\" title=\"Previous cancer comorbidity related to Chronic pulmonary disease\">chronicPulmonaryDisease</a><a name=\"Subject.comorbidity.chronicPulmonaryDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Chronic pulmonary disease<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.connectiveTissueDisease\" title=\"Previous cancer comorbidity related to Connective tissue disease\">connectiveTissueDisease</a><a name=\"Subject.comorbidity.connectiveTissueDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Connective tissue disease<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.ulcer\" title=\"Previous cancer comorbidity related to Ulcer\">ulcer</a><a name=\"Subject.comorbidity.ulcer\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Ulcer<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.mildLiverDisease\" title=\"Previous cancer comorbidity related to Mild liver disease\">mildLiverDisease</a><a name=\"Subject.comorbidity.mildLiverDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Mild liver disease<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.moderateToSevereLiverDisease\" title=\"Previous cancer comorbidity related to Moderate to severe liver disease\">moderateToSevereLiverDisease</a><a name=\"Subject.comorbidity.moderateToSevereLiverDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Moderate to severe liver disease<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.diabetes\" title=\"Previous cancer comorbidity related to Diabetes (without complications)\">diabetes</a><a name=\"Subject.comorbidity.diabetes\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Diabetes (without complications)<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.diabetesWithEndOrganDamage\" title=\"Previous cancer comorbidity related to Diabetes with end organ damage\">diabetesWithEndOrganDamage</a><a name=\"Subject.comorbidity.diabetesWithEndOrganDamage\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Diabetes with end organ damage<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.hemiplegia\" title=\"Previous cancer comorbidity related to Hemiplegia\">hemiplegia</a><a name=\"Subject.comorbidity.hemiplegia\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Hemiplegia<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.moderateToSevereRenalDisease\" title=\"Previous cancer comorbidity related to Moderate to severe renal disease\">moderateToSevereRenalDisease</a><a name=\"Subject.comorbidity.moderateToSevereRenalDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Moderate to severe renal disease<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.solidTumor\" title=\"Previous cancer comorbidity related to Solid tumor (non metastatic)\">solidTumor</a><a name=\"Subject.comorbidity.solidTumor\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Solid tumor (non metastatic)<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.metastaticSolidTumor\" title=\"Previous cancer comorbidity related to Metastatic solid tumor\">metastaticSolidTumor</a><a name=\"Subject.comorbidity.metastaticSolidTumor\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Metastatic solid tumor<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.leukemia\" title=\"Previous cancer comorbidity related to Leukemia\">leukemia</a><a name=\"Subject.comorbidity.leukemia\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Leukemia<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.lymphoma\" title=\"Previous cancer comorbidity related to Lymphoma\">lymphoma</a><a name=\"Subject.comorbidity.lymphoma\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Lymphoma<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.multipleMyeloma\" title=\"Previous cancer comorbidity related to Multiple myeloma\">multipleMyeloma</a><a name=\"Subject.comorbidity.multipleMyeloma\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Multiple myeloma<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.comorbidity.aids\" title=\"Previous cancer comorbidity related to AIDS\">aids</a><a name=\"Subject.comorbidity.aids\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">AIDS<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.ecogPsAtDiagnosis\" title=\"Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis\">ecogPsAtDiagnosis</a><a name=\"Subject.ecogPsAtDiagnosis\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.ecogPsLabel\" title=\"Eastern Cooperative Oncology Group performance status (ECOG PS)  label\">ecogPsLabel</a><a name=\"Subject.ecogPsLabel\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">ECOG PS label<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.karnofsyIndexAtDiagnosis\" title=\"Karnofsy index at diagnosis\">karnofsyIndexAtDiagnosis</a><a name=\"Subject.karnofsyIndexAtDiagnosis\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Karnofsy index at diagnosis<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.karnofsyIndexLabel\" title=\"Karnofsy index at diagnosis\">karnofsyIndexLabel</a><a name=\"Subject.karnofsyIndexLabel\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Karnofsy index label<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-headneck-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020\" title=\"Describes whether the patient was diagnosed before treatment of at least one of the diseases, syndromes listed  next (or not) relevant for sarcoma.\">noGeneticSyndromeWho2020</a><a name=\"Subject.noGeneticSyndromeWho2020\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">No Genetic syndrome WHO 2020<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.olliersDisease\" title=\"Olliers disease\">olliersDisease</a><a name=\"Subject.noGeneticSyndromeWho2020.olliersDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Olliers disease<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.maffuciSyndrome\" title=\"Maffuci syndrome\">maffuciSyndrome</a><a name=\"Subject.noGeneticSyndromeWho2020.maffuciSyndrome\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Maffuci syndrome<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome\" title=\"Li-Fraumeni syndrome\">liFraumeniSyndrome</a><a name=\"Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Li-Fraumeni syndrome<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome\" title=\"McCune-Albright syndrome\">mcCuneAlbrightSyndrome</a><a name=\"Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">McCune-Albright syndrome<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.multipleOsteochondromas\" title=\"Multiple osteochondromas\">multipleOsteochondromas</a><a name=\"Subject.noGeneticSyndromeWho2020.multipleOsteochondromas\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Multiple osteochondromas<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.neurofibromatosisType1\" title=\"Neurofibromatosis type 2\">neurofibromatosisType1</a><a name=\"Subject.noGeneticSyndromeWho2020.neurofibromatosisType1\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Neurofibromatosis type 1<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome\" title=\"Rothmund-Thomson syndrome\">rothmundThomsonSyndrome</a><a name=\"Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Rothmund-Thomson syndrome<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.wernerSyndrome\" title=\"Werner syndrome\">wernerSyndrome</a><a name=\"Subject.noGeneticSyndromeWho2020.wernerSyndrome\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Werner syndrome<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.retinoblastoma\" title=\"Retinoblastoma\">retinoblastoma</a><a name=\"Subject.noGeneticSyndromeWho2020.retinoblastoma\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Retinoblastoma<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.pagetDisease\" title=\"Paget disease\">pagetDisease</a><a name=\"Subject.noGeneticSyndromeWho2020.pagetDisease\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Paget disease<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.noGeneticSyndromeWho2020.otherSyndromes\" title=\"Other Genetic syndrome WHO 2020\">otherSyndromes</a><a name=\"Subject.noGeneticSyndromeWho2020.otherSyndromes\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\">boolean</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Other Genetic syndrome WHO 2020<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.occurrenceOfOtherCancer\" title=\"Occurrence of other cancer\">occurrenceOfOtherCancer</a><a name=\"Subject.occurrenceOfOtherCancer\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Occurrence of other cancer<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck00.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-Subject-definitions.html#Subject.previousCancerTreatment\" title=\"Previous cancer treatment\">previousCancerTreatment</a><a name=\"Subject.previousCancerTreatment\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: white; background-color: red\" title=\"This element has obligations\">O</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Previous cancer treatment<table class=\"grid\"><tr><td style=\"font-size: 11px\"><b>Obligations</b></td><td style=\"font-size: 11px\"><b>Actor</b></td></tr><tr><td style=\"font-size: 11px\"><b>SHALL</b>:<span title=\"obligation: handle\">handle</span></td><td style=\"font-size: 11px; opacity: 0.5;\"><a href=\"ActorDefinition-actor-sarcoma-i4rc.html\"/></td></tr></table></td></tr>\r\n<tr><td colspan=\"5\" class=\"hierarchy\"><br/><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
  },
  "url" : "http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject",
  "version" : "0.1.0",
  "name" : "SubjectI4rc",
  "title" : "Subject of care",
  "status" : "draft",
  "date" : "2024-11-12T10:15:38+00:00",
  "publisher" : "IDEA4RC Project",
  "contact" : [
    {
      "name" : "IDEA4RC Project",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://www.idea4rc.eu/"
        }
      ]
    },
    {
      "name" : "IDEA4RC Project",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://www.idea4rc.eu/"
        }
      ]
    }
  ],
  "description" : "Subject of care \nMaturity Level: 0 Draft",
  "jurisdiction" : [
    {
      "coding" : [
        {
          "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code" : "150",
          "display" : "Europe"
        }
      ]
    }
  ],
  "fhirVersion" : "4.0.1",
  "kind" : "logical",
  "abstract" : false,
  "type" : "http://hl7.eu/fhir/ig/idea4rc/StructureDefinition/Subject",
  "baseDefinition" : "http://hl7.org/fhir/StructureDefinition/Base",
  "derivation" : "specialization",
  "snapshot" : {
    "element" : [
      {
        "id" : "Subject",
        "path" : "Subject",
        "short" : "Subject of care",
        "definition" : "Subject of care \nMaturity Level: 0 Draft",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Base",
          "min" : 0,
          "max" : "*"
        },
        "isModifier" : false
      },
      {
        "id" : "Subject.sex",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.sex",
        "short" : "Gender",
        "definition" : "Describes biological sex as recorded in the patient's identity document or in the hospital record. In the absence of documentation, the one declared by the patient will be recorded",
        "comment" : "Male; Female; Unknown.\nMale - 8507\nFemale - 8532\nUnknown - 4129922",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.sex",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.race",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.race",
        "short" : "Race",
        "definition" : "Describes race as recorded in  the hospital record, the one declared by the patient,, otherwise, the onerecognized by the observer",
        "comment" : "Unknown; White; Black; Asians/Pacific Islanders; American Indian/Alaska Native\nWhite - 8527\nBlack - 8516\nAsian/Pacific Islanders - 8515\nAmerican Indian/Alaska Native - 8657\nUnknown - 4129922",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.race",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.birthYear",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.birthYear",
        "short" : "Birth year",
        "definition" : "Year of birth of the patient.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.birthYear",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.countryOfResidence",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.countryOfResidence",
        "short" : "Country of Residence",
        "definition" : "Country of residence at the time of diagnosis",
        "comment" : "Value from the code list of countries\nSon in the hierarchy of countries",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.countryOfResidence",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.smoking",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.smoking",
        "short" : "Smoking",
        "definition" : "Describes tobacco smoker habits within the options proposed",
        "comment" : "Current tobacco smoker; Former smoker (at least for 12 months); Never smoker; Unknown\nCurrent smoker - 36309332\nFormer smoker - 45883458\nNever smoker - 45879404",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.smoking",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.cigarettesPackYearsSmokedDuringLife",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.cigarettesPackYearsSmokedDuringLife",
        "short" : "Cigarettes pack years smoked during life",
        "definition" : "The amount of cigarette pack smoked during life",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.cigarettesPackYearsSmokedDuringLife",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.alcohol",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.alcohol",
        "short" : "Alcohol",
        "definition" : "Describes alcohol habits within the options proposed",
        "comment" : "Current; Former (at least for 12 months); Never; History of alcohol dependence; Unknown\nCurrent drinker - 4074035\nEx-drinker - 4220362\nLifetime non-drinker of alcohol - 37204556\nEx-problem drinker - 4117706",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.alcohol",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.bMI",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.bMI",
        "short" : "Height/weight (BMI)",
        "definition" : "Body Mass Index information if weight and height are included. it is calculated as BMI = kg/m2 where kg is a person's weight in kilograms and m2 is their height in metres squared.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.bMI",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "Quantity"
          }
        ]
      },
      {
        "id" : "Subject.charlsonComorbidityIndex",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.charlsonComorbidityIndex",
        "short" : "Charlson Comorbidity index",
        "definition" : "Provides the Charlson Comorbidity index for the patient",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.charlsonComorbidityIndex",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity",
        "short" : "Comorbidity",
        "definition" : "Describes whether the patient was diagnosed before treatment of at least one of the comorbidities listed  next (or not) relevant for head and neck cancer.",
        "comment" : "Yes; No; Unknown\nYes - 4188539\nNo -  4188540\nUnknown - 4129922",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "BackboneElement"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.id",
        "path" : "Subject.comorbidity.id",
        "representation" : [
          "xmlAttr"
        ],
        "short" : "Unique id for inter-element referencing",
        "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Element.id",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl" : "string"
              }
            ],
            "code" : "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "n/a"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.extension",
        "path" : "Subject.comorbidity.extension",
        "slicing" : {
          "discriminator" : [
            {
              "type" : "value",
              "path" : "url"
            }
          ],
          "description" : "Extensions are always sliced by (at least) url",
          "rules" : "open"
        },
        "short" : "Additional content defined by implementations",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias" : [
          "extensions",
          "user content"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Element.extension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key" : "ext-1",
            "severity" : "error",
            "human" : "Must have either extensions or value[x], not both",
            "expression" : "extension.exists() != value.exists()",
            "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "n/a"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.modifierExtension",
        "path" : "Subject.comorbidity.modifierExtension",
        "short" : "Extensions that cannot be ignored even if unrecognized",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
        "alias" : [
          "extensions",
          "user content",
          "modifiers"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "BackboneElement.modifierExtension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key" : "ext-1",
            "severity" : "error",
            "human" : "Must have either extensions or value[x], not both",
            "expression" : "extension.exists() != value.exists()",
            "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier" : true,
        "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "N/A"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.myocardialInfarction",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.myocardialInfarction",
        "short" : "Myocardial infarction",
        "definition" : "Describes comorbidities reported or assesed before treatment. More than one choice is allowed. Please do not include the current cancer in this calculation, only the previous cancer.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.myocardialInfarction",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.congestiveHeartFailure",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.congestiveHeartFailure",
        "short" : "Congestive heart failure",
        "definition" : "Previous cancer comorbidity related to Congestive heart failure",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.congestiveHeartFailure",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.peripheralVascularDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.peripheralVascularDisease",
        "short" : "Peripheral vascular disease",
        "definition" : "Previous cancer comorbidity related to Peripheral vascular disease",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.peripheralVascularDisease",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia",
        "short" : "Cerebrovascular accident  (except hemiplegia)",
        "definition" : "Previous cancer comorbidity related to Cerebrovascular accident  (except hemiplegia)",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.dementia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.dementia",
        "short" : "Dementia",
        "definition" : "Previous cancer comorbidity related to Dementia",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.dementia",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.chronicPulmonaryDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.chronicPulmonaryDisease",
        "short" : "Chronic pulmonary disease",
        "definition" : "Previous cancer comorbidity related to Chronic pulmonary disease",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.chronicPulmonaryDisease",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.connectiveTissueDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.connectiveTissueDisease",
        "short" : "Connective tissue disease",
        "definition" : "Previous cancer comorbidity related to Connective tissue disease",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.connectiveTissueDisease",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.ulcer",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.ulcer",
        "short" : "Ulcer",
        "definition" : "Previous cancer comorbidity related to Ulcer",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.ulcer",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.mildLiverDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.mildLiverDisease",
        "short" : "Mild liver disease",
        "definition" : "Previous cancer comorbidity related to Mild liver disease",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.mildLiverDisease",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.moderateToSevereLiverDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.moderateToSevereLiverDisease",
        "short" : "Moderate to severe liver disease",
        "definition" : "Previous cancer comorbidity related to Moderate to severe liver disease",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.moderateToSevereLiverDisease",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.diabetes",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.diabetes",
        "short" : "Diabetes (without complications)",
        "definition" : "Previous cancer comorbidity related to Diabetes (without complications)",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.diabetes",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.diabetesWithEndOrganDamage",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.diabetesWithEndOrganDamage",
        "short" : "Diabetes with end organ damage",
        "definition" : "Previous cancer comorbidity related to Diabetes with end organ damage",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.diabetesWithEndOrganDamage",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.hemiplegia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.hemiplegia",
        "short" : "Hemiplegia",
        "definition" : "Previous cancer comorbidity related to Hemiplegia",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.hemiplegia",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.moderateToSevereRenalDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.moderateToSevereRenalDisease",
        "short" : "Moderate to severe renal disease",
        "definition" : "Previous cancer comorbidity related to Moderate to severe renal disease",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.moderateToSevereRenalDisease",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.solidTumor",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.solidTumor",
        "short" : "Solid tumor (non metastatic)",
        "definition" : "Previous cancer comorbidity related to Solid tumor (non metastatic)",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.solidTumor",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.metastaticSolidTumor",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.metastaticSolidTumor",
        "short" : "Metastatic solid tumor",
        "definition" : "Previous cancer comorbidity related to Metastatic solid tumor",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.metastaticSolidTumor",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.leukemia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.leukemia",
        "short" : "Leukemia",
        "definition" : "Previous cancer comorbidity related to Leukemia",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.leukemia",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.lymphoma",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.lymphoma",
        "short" : "Lymphoma",
        "definition" : "Previous cancer comorbidity related to Lymphoma",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.lymphoma",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.multipleMyeloma",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.multipleMyeloma",
        "short" : "Multiple myeloma",
        "definition" : "Previous cancer comorbidity related to Multiple myeloma",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.multipleMyeloma",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.aids",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.aids",
        "short" : "AIDS",
        "definition" : "Previous cancer comorbidity related to AIDS",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.comorbidity.aids",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.ecogPsAtDiagnosis",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.ecogPsAtDiagnosis",
        "short" : "Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis",
        "definition" : "Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis",
        "comment" : "Ecog grades 0-5",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.ecogPsAtDiagnosis",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.ecogPsLabel",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.ecogPsLabel",
        "short" : "ECOG PS label",
        "definition" : "Eastern Cooperative Oncology Group performance status (ECOG PS)  label",
        "comment" : "Ecog grades 0-5\n\nECOG performance status grade 0 - 4175026\nECOG performance status grade 1 - 4173614\nECOG performance status grade 2 - 4172043\nECOG performance status grade 3 - 4174241\nECOG performance status grade 4 - 4174251\nECOG performance status grade 5 - 4173456",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.ecogPsLabel",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.karnofsyIndexAtDiagnosis",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.karnofsyIndexAtDiagnosis",
        "short" : "Karnofsy index at diagnosis",
        "definition" : "Karnofsy index at diagnosis",
        "comment" : "KPS Scale",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.karnofsyIndexAtDiagnosis",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.karnofsyIndexLabel",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.karnofsyIndexLabel",
        "short" : "Karnofsy index label",
        "definition" : "Karnofsy index at diagnosis",
        "comment" : "KPS Scale\nSONS Functional Neurologic Status - Karnofsky Performance Scale (KPS) - 35917688",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Subject.karnofsyIndexLabel",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020",
        "short" : "No Genetic syndrome WHO 2020",
        "definition" : "Describes whether the patient was diagnosed before treatment of at least one of the diseases, syndromes listed  next (or not) relevant for sarcoma.",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "BackboneElement"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.id",
        "path" : "Subject.noGeneticSyndromeWho2020.id",
        "representation" : [
          "xmlAttr"
        ],
        "short" : "Unique id for inter-element referencing",
        "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Element.id",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl" : "string"
              }
            ],
            "code" : "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "n/a"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.extension",
        "path" : "Subject.noGeneticSyndromeWho2020.extension",
        "slicing" : {
          "discriminator" : [
            {
              "type" : "value",
              "path" : "url"
            }
          ],
          "description" : "Extensions are always sliced by (at least) url",
          "rules" : "open"
        },
        "short" : "Additional content defined by implementations",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias" : [
          "extensions",
          "user content"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Element.extension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key" : "ext-1",
            "severity" : "error",
            "human" : "Must have either extensions or value[x], not both",
            "expression" : "extension.exists() != value.exists()",
            "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "n/a"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.modifierExtension",
        "path" : "Subject.noGeneticSyndromeWho2020.modifierExtension",
        "short" : "Extensions that cannot be ignored even if unrecognized",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
        "alias" : [
          "extensions",
          "user content",
          "modifiers"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "BackboneElement.modifierExtension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key" : "ext-1",
            "severity" : "error",
            "human" : "Must have either extensions or value[x], not both",
            "expression" : "extension.exists() != value.exists()",
            "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier" : true,
        "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "N/A"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.olliersDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.olliersDisease",
        "short" : "Olliers disease",
        "definition" : "Olliers disease",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.olliersDisease",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.maffuciSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.maffuciSyndrome",
        "short" : "Maffuci syndrome",
        "definition" : "Maffuci syndrome",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.maffuciSyndrome",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome",
        "short" : "Li-Fraumeni syndrome",
        "definition" : "Li-Fraumeni syndrome",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome",
        "short" : "McCune-Albright syndrome",
        "definition" : "McCune-Albright syndrome",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.multipleOsteochondromas",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.multipleOsteochondromas",
        "short" : "Multiple osteochondromas",
        "definition" : "Multiple osteochondromas",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.multipleOsteochondromas",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.neurofibromatosisType1",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.neurofibromatosisType1",
        "short" : "Neurofibromatosis type 1",
        "definition" : "Neurofibromatosis type 2",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.neurofibromatosisType1",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome",
        "short" : "Rothmund-Thomson syndrome",
        "definition" : "Rothmund-Thomson syndrome",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.wernerSyndrome",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.wernerSyndrome",
        "short" : "Werner syndrome",
        "definition" : "Werner syndrome",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.wernerSyndrome",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.retinoblastoma",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.retinoblastoma",
        "short" : "Retinoblastoma",
        "definition" : "Retinoblastoma",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.retinoblastoma",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.pagetDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.pagetDisease",
        "short" : "Paget disease",
        "definition" : "Paget disease",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.pagetDisease",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.otherSyndromes",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.otherSyndromes",
        "short" : "Other Genetic syndrome WHO 2020",
        "definition" : "Other Genetic syndrome WHO 2020",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.noGeneticSyndromeWho2020.otherSyndromes",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.occurrenceOfOtherCancer",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.occurrenceOfOtherCancer",
        "short" : "Occurrence of other cancer",
        "definition" : "Occurrence of other cancer",
        "comment" : "Children (and subchildren) of Neoplasm and/or hamartoma - 4266186",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.occurrenceOfOtherCancer",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.previousCancerTreatment",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.previousCancerTreatment",
        "short" : "Previous cancer treatment",
        "definition" : "Previous cancer treatment",
        "comment" : "Chemotherapy - 4273629\nRadiation oncology- 4170755\nSurgery - 4121697 \nComprehensive medication therapy review - 42535584\nImmunological therapy - 4295112",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "Subject.previousCancerTreatment",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      }
    ]
  },
  "differential" : {
    "element" : [
      {
        "id" : "Subject",
        "path" : "Subject",
        "short" : "Subject of care",
        "definition" : "Subject of care \nMaturity Level: 0 Draft"
      },
      {
        "id" : "Subject.sex",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.sex",
        "short" : "Gender",
        "definition" : "Describes biological sex as recorded in the patient's identity document or in the hospital record. In the absence of documentation, the one declared by the patient will be recorded",
        "comment" : "Male; Female; Unknown.\nMale - 8507\nFemale - 8532\nUnknown - 4129922",
        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.race",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.race",
        "short" : "Race",
        "definition" : "Describes race as recorded in  the hospital record, the one declared by the patient,, otherwise, the onerecognized by the observer",
        "comment" : "Unknown; White; Black; Asians/Pacific Islanders; American Indian/Alaska Native\nWhite - 8527\nBlack - 8516\nAsian/Pacific Islanders - 8515\nAmerican Indian/Alaska Native - 8657\nUnknown - 4129922",
        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.birthYear",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.birthYear",
        "short" : "Birth year",
        "definition" : "Year of birth of the patient.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.countryOfResidence",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          },
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.countryOfResidence",
        "short" : "Country of Residence",
        "definition" : "Country of residence at the time of diagnosis",
        "comment" : "Value from the code list of countries\nSon in the hierarchy of countries",
        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.smoking",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.smoking",
        "short" : "Smoking",
        "definition" : "Describes tobacco smoker habits within the options proposed",
        "comment" : "Current tobacco smoker; Former smoker (at least for 12 months); Never smoker; Unknown\nCurrent smoker - 36309332\nFormer smoker - 45883458\nNever smoker - 45879404",
        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.cigarettesPackYearsSmokedDuringLife",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.cigarettesPackYearsSmokedDuringLife",
        "short" : "Cigarettes pack years smoked during life",
        "definition" : "The amount of cigarette pack smoked during life",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.alcohol",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.alcohol",
        "short" : "Alcohol",
        "definition" : "Describes alcohol habits within the options proposed",
        "comment" : "Current; Former (at least for 12 months); Never; History of alcohol dependence; Unknown\nCurrent drinker - 4074035\nEx-drinker - 4220362\nLifetime non-drinker of alcohol - 37204556\nEx-problem drinker - 4117706",
        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ]
      },
      {
        "id" : "Subject.bMI",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.bMI",
        "short" : "Height/weight (BMI)",
        "definition" : "Body Mass Index information if weight and height are included. it is calculated as BMI = kg/m2 where kg is a person's weight in kilograms and m2 is their height in metres squared.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "Quantity"
          }
        ]
      },
      {
        "id" : "Subject.charlsonComorbidityIndex",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-sarcoma-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.charlsonComorbidityIndex",
        "short" : "Charlson Comorbidity index",
        "definition" : "Provides the Charlson Comorbidity index for the patient",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "integer"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity",
        "short" : "Comorbidity",
        "definition" : "Describes whether the patient was diagnosed before treatment of at least one of the comorbidities listed  next (or not) relevant for head and neck cancer.",
        "comment" : "Yes; No; Unknown\nYes - 4188539\nNo -  4188540\nUnknown - 4129922",
        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "BackboneElement"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.myocardialInfarction",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.myocardialInfarction",
        "short" : "Myocardial infarction",
        "definition" : "Describes comorbidities reported or assesed before treatment. More than one choice is allowed. Please do not include the current cancer in this calculation, only the previous cancer.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.congestiveHeartFailure",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.congestiveHeartFailure",
        "short" : "Congestive heart failure",
        "definition" : "Previous cancer comorbidity related to Congestive heart failure",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.peripheralVascularDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.peripheralVascularDisease",
        "short" : "Peripheral vascular disease",
        "definition" : "Previous cancer comorbidity related to Peripheral vascular disease",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.cerebrovascularAccidentExceptHemiplegia",
        "short" : "Cerebrovascular accident  (except hemiplegia)",
        "definition" : "Previous cancer comorbidity related to Cerebrovascular accident  (except hemiplegia)",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.dementia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.dementia",
        "short" : "Dementia",
        "definition" : "Previous cancer comorbidity related to Dementia",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.chronicPulmonaryDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.chronicPulmonaryDisease",
        "short" : "Chronic pulmonary disease",
        "definition" : "Previous cancer comorbidity related to Chronic pulmonary disease",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.connectiveTissueDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.connectiveTissueDisease",
        "short" : "Connective tissue disease",
        "definition" : "Previous cancer comorbidity related to Connective tissue disease",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.ulcer",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.ulcer",
        "short" : "Ulcer",
        "definition" : "Previous cancer comorbidity related to Ulcer",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.mildLiverDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.mildLiverDisease",
        "short" : "Mild liver disease",
        "definition" : "Previous cancer comorbidity related to Mild liver disease",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.moderateToSevereLiverDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.moderateToSevereLiverDisease",
        "short" : "Moderate to severe liver disease",
        "definition" : "Previous cancer comorbidity related to Moderate to severe liver disease",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.diabetes",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.diabetes",
        "short" : "Diabetes (without complications)",
        "definition" : "Previous cancer comorbidity related to Diabetes (without complications)",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.diabetesWithEndOrganDamage",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.diabetesWithEndOrganDamage",
        "short" : "Diabetes with end organ damage",
        "definition" : "Previous cancer comorbidity related to Diabetes with end organ damage",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.hemiplegia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.hemiplegia",
        "short" : "Hemiplegia",
        "definition" : "Previous cancer comorbidity related to Hemiplegia",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.moderateToSevereRenalDisease",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.moderateToSevereRenalDisease",
        "short" : "Moderate to severe renal disease",
        "definition" : "Previous cancer comorbidity related to Moderate to severe renal disease",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.solidTumor",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.solidTumor",
        "short" : "Solid tumor (non metastatic)",
        "definition" : "Previous cancer comorbidity related to Solid tumor (non metastatic)",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.metastaticSolidTumor",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.metastaticSolidTumor",
        "short" : "Metastatic solid tumor",
        "definition" : "Previous cancer comorbidity related to Metastatic solid tumor",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.leukemia",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.leukemia",
        "short" : "Leukemia",
        "definition" : "Previous cancer comorbidity related to Leukemia",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.lymphoma",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.lymphoma",
        "short" : "Lymphoma",
        "definition" : "Previous cancer comorbidity related to Lymphoma",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
          }
        ]
      },
      {
        "id" : "Subject.comorbidity.multipleMyeloma",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
              },
              {
                "url" : "actor",
                "valueCanonical" : "http://hl7.eu/fhir/ig/idea4rc/actor-headneck-i4rc"
              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.multipleMyeloma",
        "short" : "Multiple myeloma",
        "definition" : "Previous cancer comorbidity related to Multiple myeloma",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
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        ]
      },
      {
        "id" : "Subject.comorbidity.aids",
        "extension" : [
          {
            "extension" : [
              {
                "url" : "code",
                "valueCode" : "SHALL:handle"
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              {
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            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.comorbidity.aids",
        "short" : "AIDS",
        "definition" : "Previous cancer comorbidity related to AIDS",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
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        ]
      },
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          {
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              {
                "url" : "code",
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              {
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              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
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        ],
        "path" : "Subject.ecogPsAtDiagnosis",
        "short" : "Eastern Cooperative Oncology Group performance status (ECOG PS)  at diagnosis",
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        ],
        "path" : "Subject.ecogPsLabel",
        "short" : "ECOG PS label",
        "definition" : "Eastern Cooperative Oncology Group performance status (ECOG PS)  label",
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            ],
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        ],
        "path" : "Subject.karnofsyIndexAtDiagnosis",
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          {
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              {
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              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.karnofsyIndexLabel",
        "short" : "Karnofsy index label",
        "definition" : "Karnofsy index at diagnosis",
        "comment" : "KPS Scale\nSONS Functional Neurologic Status - Karnofsky Performance Scale (KPS) - 35917688 ",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
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        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020",
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          {
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              {
                "url" : "code",
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              {
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              }
            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020",
        "short" : "No Genetic syndrome WHO 2020",
        "definition" : "Describes whether the patient was diagnosed before treatment of at least one of the diseases, syndromes listed  next (or not) relevant for sarcoma.",
        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "BackboneElement"
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        ]
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          {
            "extension" : [
              {
                "url" : "code",
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            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.olliersDisease",
        "short" : "Olliers disease",
        "definition" : "Olliers disease",
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        "max" : "1",
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          {
            "code" : "boolean"
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        ]
      },
      {
        "id" : "Subject.noGeneticSyndromeWho2020.maffuciSyndrome",
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          {
            "extension" : [
              {
                "url" : "code",
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              {
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            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
          }
        ],
        "path" : "Subject.noGeneticSyndromeWho2020.maffuciSyndrome",
        "short" : "Maffuci syndrome",
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        "min" : 1,
        "max" : "1",
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          {
            "code" : "boolean"
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        ]
      },
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          {
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            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
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        ],
        "path" : "Subject.noGeneticSyndromeWho2020.liFraumeniSyndrome",
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        "min" : 1,
        "max" : "1",
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          {
            "code" : "boolean"
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        "id" : "Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome",
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            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
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        ],
        "path" : "Subject.noGeneticSyndromeWho2020.mcCuneAlbrightSyndrome",
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        "min" : 1,
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        "type" : [
          {
            "code" : "boolean"
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          {
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                "url" : "code",
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            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
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        ],
        "path" : "Subject.noGeneticSyndromeWho2020.multipleOsteochondromas",
        "short" : "Multiple osteochondromas",
        "definition" : "Multiple osteochondromas",
        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
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          {
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                "url" : "code",
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            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
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        ],
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        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "boolean"
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        "id" : "Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome",
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          {
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                "url" : "code",
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            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
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        ],
        "path" : "Subject.noGeneticSyndromeWho2020.rothmundThomsonSyndrome",
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        "max" : "1",
        "type" : [
          {
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        ],
        "path" : "Subject.noGeneticSyndromeWho2020.retinoblastoma",
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        "max" : "1",
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          {
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        ],
        "path" : "Subject.noGeneticSyndromeWho2020.pagetDisease",
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        "path" : "Subject.noGeneticSyndromeWho2020.otherSyndromes",
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        "definition" : "Other Genetic syndrome WHO 2020",
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        "max" : "1",
        "type" : [
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          {
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            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
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        ],
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        "max" : "1",
        "type" : [
          {
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        "id" : "Subject.previousCancerTreatment",
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          {
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            ],
            "url" : "http://hl7.org/fhir/StructureDefinition/obligation"
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        ],
        "path" : "Subject.previousCancerTreatment",
        "short" : "Previous cancer treatment",
        "definition" : "Previous cancer treatment",
        "comment" : "Chemotherapy - 4273629\nRadiation oncology- 4170755\nSurgery - 4121697 \nComprehensive medication therapy review - 42535584\nImmunological therapy - 4295112",
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}