Medication Scheme Implementation Guide
1.0.0 - draft
Medication Scheme Implementation Guide
1.0.0 - draft
Medication Scheme Implementation Guide, published by TEHIK. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/TEHIK-EE/ig-ee-medication-scheme/ and changes regularly. See the Directory of published versions
| Official URL: https://fhir.ee/StructureDefinition/ee-tis-renal-failure-ds | Version: 1.0.0 | |||
| Draft as of 2024-02-22 | Computable Name: EETISRenalFailureDS | |||
Neerufuntsiooni puudulikkuse otsustustoe vastus. This profile is for the representation of patient's renal function failure and alerts about it so the medication can be adjusted according to failure degree.
Usages:
You can also check for usages in the FHIR IG Statistics
Description of Profiles, Differentials, Snapshots and how the different presentations work.
| Name | Flags | Card. | Type | Description & Constraints Filter:   |
|---|---|---|---|---|
  ClinicalUseDefinition |
C | 0..* | ClinicalUseDefinition | A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure Constraints: cud-1 |
  implicitRules |
?!Σ | 0..1 | uri | A set of rules under which this content was created |
| contained |
1..1 | Medication | Contained, inline Resources | |
  Slices for extension |
0..* | Extension | Extension Slice: Unordered, Open by value:url | |
   extension:affected |
0..* | Reference(EETISMedicationStatement) | MedicationStatements affected by interactions. URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements | |
| extension:link |
0..* | string | Additional information from external source. URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link | |
| extension:nephrotoxic |
0..* | boolean | Is the medication nephrotoxic or not. URL: https://fhir.ee/StructureDefinition/ee-tis-nephrotoxic | |
| extension:dosageModification |
0..* | (Complex) | Recommendation for dosaging URL: https://fhir.ee/StructureDefinition/ee-tis-dosage-modification | |
 extension:relatedObservation |
0..* | Reference(Observation | Condition) | Observation/Condition which triggers renal function alert. URL: https://fhir.ee/StructureDefinition/ee-tis-related-observation-or-condition | |
 modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored |
| type |
Σ | 1..1 | code | indication | contraindication | interaction | undesirable-effect | warning Binding: ClinicalUseDefinitionType (required): Overall defining type of this clinical use definition. Fixed Value: undesirable-effect |
 Slices for category |
Σ | 0..* | CodeableConcept | RenBase drugFormGroup ja failureDegree Slice: Unordered, Open by value:coding Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. |
 category:drugFormGroup |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. |
   coding |
Σ | 1..* | Coding | 0 | 1 | 2 | 3 | 4 | 5| This is a fake system for example. Do NOT use it! Required Pattern: At least the following |
 id |
0..1 | string | Unique id for inter-element referencing | |
| extension |
0..* | Extension | Additional content defined by implementations | |
 system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/drug-form-group | |
| version |
0..1 | string | Version of the system - if relevant | |
| code |
0..1 | code | Symbol in syntax defined by the system | |
| display |
0..1 | string | Representation defined by the system | |
 userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |
| category:failureDegree |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. |
| coding |
Σ | 1..* | Coding | Failure degree 0-4. Neerupuudulikkuse aste: number + selgitus. This is a fake system for example. Do NOT use it! Required Pattern: At least the following |
| id |
0..1 | string | Unique id for inter-element referencing | |
| extension |
0..* | Extension | Additional content defined by implementations | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/failure-degree | |
| version |
0..1 | string | Version of the system - if relevant | |
| code |
0..1 | code | Symbol in syntax defined by the system | |
| display |
0..1 | string | Representation defined by the system | |
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |
 category:additionalInformation |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. |
| coding |
Σ | 1..* | Coding | This is a fake system for example. Do NOT use it Required Pattern: At least the following |
| id |
0..1 | string | Unique id for inter-element referencing | |
| extension |
0..* | Extension | Additional content defined by implementations | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/additional-information | |
| version |
0..1 | string | Version of the system - if relevant | |
| code |
0..1 | code | Symbol in syntax defined by the system | |
| display |
0..1 | string | Representation defined by the system | |
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |
 subject |
Σ | 1..* | Reference(Medication) | medication that may cause renal function failure |
| reference |
ΣC | 0..1 | string | Literal reference, Relative, internal or absolute URL |
| display |
ΣC | 0..1 | string | Text alternative for the resource Required Pattern: Name of the medication/active inredient. Siia toimeaine nimetus |
 undesirableEffect |
ΣC | 0..1 | BackboneElement | Classification A/B/C/D and description how the dosage must be adjusted |
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized |
| classification |
Σ | 0..1 | CodeableConcept | klassifikatsioon (A/B/C/D) + selle tekst nt C, text: Annust või annustamise vahemikku tuleb kohandada Binding: UndesirableEffectClassification (example): Use this fictive system https://fhir.ee/synbase-warning-classification |
| Documentation for this format | ||||
| Path | Status | Usage | ValueSet | Version | Source |
| ClinicalUseDefinition.type | Base | required | Clinical Use Definition Type | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:drugFormGroup | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:failureDegree | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:additionalInformation | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.undesirableEffect.classification | Base | example | Undesirable Effect Classification | 📦5.0.0 | FHIR Std. |
| Id | Grade | Path(s) | Description | Expression |
| cud-1 | error | ClinicalUseDefinition | Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot be used in the same instance |
(ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count() + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count() + ClinicalUseDefinition.warning.count()) < 2
|
| dom-2 | error | ClinicalUseDefinition | If the resource is contained in another resource, it SHALL NOT contain nested Resources |
contained.contained.empty()
|
| dom-3 | error | ClinicalUseDefinition | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource |
contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
|
| dom-4 | error | ClinicalUseDefinition | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated |
contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
|
| dom-5 | error | ClinicalUseDefinition | If a resource is contained in another resource, it SHALL NOT have a security label |
contained.meta.security.empty()
|
| dom-6 | best practice | ClinicalUseDefinition | A resource should have narrative for robust management |
text.`div`.exists()
|
| ele-1 | error | **ALL** elements | All FHIR elements must have a @value or children |
hasValue() or (children().count() > id.count())
|
| ext-1 | error | **ALL** extensions | Must have either extensions or value[x], not both |
extension.exists() != value.exists()
|
This structure is derived from ClinicalUseDefinition
| Name | Flags | Card. | Type | Description & Constraints Filter: |
|---|---|---|---|---|
| ClinicalUseDefinition |
ClinicalUseDefinition | |||
| contained |
1..1 | Medication | Contained, inline Resources | |
| Slices for extension |
0..* | Extension | Extension Slice: Unordered, Open by value:url | |
| extension:affected |
0..* | Reference(EETISMedicationStatement) | MedicationStatements affected by interactions. URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements | |
| extension:link |
0..* | string | Additional information from external source. URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link | |
| extension:nephrotoxic |
0..* | boolean | Is the medication nephrotoxic or not. URL: https://fhir.ee/StructureDefinition/ee-tis-nephrotoxic | |
| extension:dosageModification |
0..* | (Complex) | Recommendation for dosaging URL: https://fhir.ee/StructureDefinition/ee-tis-dosage-modification | |
| extension:relatedObservation |
0..* | Reference(Observation | Condition) | Observation/Condition which triggers renal function alert. URL: https://fhir.ee/StructureDefinition/ee-tis-related-observation-or-condition | |
 type |
1..1 | code | indication | contraindication | interaction | undesirable-effect | warning Fixed Value: undesirable-effect | |
| Slices for category |
0..* | CodeableConcept | RenBase drugFormGroup ja failureDegree Slice: Unordered, Open by value:coding | |
| category:drugFormGroup |
0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" | |
| coding |
1..* | Coding | 0 | 1 | 2 | 3 | 4 | 5| This is a fake system for example. Do NOT use it! Required Pattern: At least the following | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/drug-form-group | |
| category:failureDegree |
0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" | |
| coding |
1..* | Coding | Failure degree 0-4. Neerupuudulikkuse aste: number + selgitus. This is a fake system for example. Do NOT use it! Required Pattern: At least the following | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/failure-degree | |
| category:additionalInformation |
0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" | |
| coding |
1..* | Coding | This is a fake system for example. Do NOT use it Required Pattern: At least the following | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/additional-information | |
| subject |
1..* | Reference(Medication) | medication that may cause renal function failure | |
| display |
0..1 | string | Text alternative for the resource Required Pattern: Name of the medication/active inredient. Siia toimeaine nimetus | |
| contraindication |
0..0 | |||
| indication |
0..0 | |||
| population |
0..0 | |||
| library |
0..0 | |||
| undesirableEffect |
0..1 | BackboneElement | Classification A/B/C/D and description how the dosage must be adjusted | |
| classification |
0..1 | CodeableConcept | klassifikatsioon (A/B/C/D) + selle tekst nt C, text: Annust või annustamise vahemikku tuleb kohandada Binding: UndesirableEffectClassification (example): Use this fictive system https://fhir.ee/synbase-warning-classification | |
| Documentation for this format | ||||
| Path | Status | Usage | ValueSet | Version | Source |
| ClinicalUseDefinition.undesirableEffect.classification | Base | example | Undesirable Effect Classification | 📦5.0.0 | FHIR Std. |
| Name | Flags | Card. | Type | Description & Constraints Filter: | ||||
|---|---|---|---|---|---|---|---|---|
| ClinicalUseDefinition |
C | 0..* | ClinicalUseDefinition | A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure Constraints: cud-1 | ||||
| id |
Σ | 0..1 | id | Logical id of this artifact | ||||
| meta |
Σ | 0..1 | Meta | Metadata about the resource | ||||
| implicitRules |
?!Σ | 0..1 | uri | A set of rules under which this content was created | ||||
| language |
0..1 | code | Language of the resource content Binding: AllLanguages (required): IETF language tag for a human language
| |||||
| text |
0..1 | Narrative | Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements | |||||
| contained |
1..1 | Medication | Contained, inline Resources | |||||
| Slices for extension |
0..* | Extension | Extension Slice: Unordered, Open by value:url | |||||
| extension:affected |
0..* | Reference(EETISMedicationStatement) | MedicationStatements affected by interactions. URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements | |||||
| extension:link |
0..* | string | Additional information from external source. URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link | |||||
| extension:nephrotoxic |
0..* | boolean | Is the medication nephrotoxic or not. URL: https://fhir.ee/StructureDefinition/ee-tis-nephrotoxic | |||||
| extension:dosageModification |
0..* | (Complex) | Recommendation for dosaging URL: https://fhir.ee/StructureDefinition/ee-tis-dosage-modification | |||||
| extension:relatedObservation |
0..* | Reference(Observation | Condition) | Observation/Condition which triggers renal function alert. URL: https://fhir.ee/StructureDefinition/ee-tis-related-observation-or-condition | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored | ||||
| identifier |
Σ | 0..* | Identifier | Business identifier for this issue | ||||
| type |
Σ | 1..1 | code | indication | contraindication | interaction | undesirable-effect | warning Binding: ClinicalUseDefinitionType (required): Overall defining type of this clinical use definition. Fixed Value: undesirable-effect | ||||
| Slices for category |
Σ | 0..* | CodeableConcept | RenBase drugFormGroup ja failureDegree Slice: Unordered, Open by value:coding Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. | ||||
| category:drugFormGroup |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. | ||||
 id |
0..1 | id | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Slice: Unordered, Open by value:url | |||||
 coding |
Σ | 1..* | Coding | 0 | 1 | 2 | 3 | 4 | 5| This is a fake system for example. Do NOT use it! Required Pattern: At least the following | ||||
 id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/drug-form-group | |||||
| version |
0..1 | string | Version of the system - if relevant | |||||
| code |
0..1 | code | Symbol in syntax defined by the system | |||||
| display |
0..1 | string | Representation defined by the system | |||||
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |||||
 text |
Σ | 0..1 | string | Plain text representation of the concept | ||||
| category:failureDegree |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. | ||||
| id |
0..1 | id | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Slice: Unordered, Open by value:url | |||||
| coding |
Σ | 1..* | Coding | Failure degree 0-4. Neerupuudulikkuse aste: number + selgitus. This is a fake system for example. Do NOT use it! Required Pattern: At least the following | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/failure-degree | |||||
| version |
0..1 | string | Version of the system - if relevant | |||||
| code |
0..1 | code | Symbol in syntax defined by the system | |||||
| display |
0..1 | string | Representation defined by the system | |||||
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |||||
| text |
Σ | 0..1 | string | Plain text representation of the concept | ||||
| category:additionalInformation |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. | ||||
| id |
0..1 | id | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Slice: Unordered, Open by value:url | |||||
| coding |
Σ | 1..* | Coding | This is a fake system for example. Do NOT use it Required Pattern: At least the following | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/additional-information | |||||
| version |
0..1 | string | Version of the system - if relevant | |||||
| code |
0..1 | code | Symbol in syntax defined by the system | |||||
| display |
0..1 | string | Representation defined by the system | |||||
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |||||
| text |
Σ | 0..1 | string | Plain text representation of the concept | ||||
| subject |
Σ | 1..* | Reference(Medication) | medication that may cause renal function failure | ||||
| id |
0..1 | id | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Slice: Unordered, Open by value:url | |||||
| reference |
ΣC | 0..1 | string | Literal reference, Relative, internal or absolute URL | ||||
| type |
Σ | 0..1 | uri | Type the reference refers to (e.g. "Patient") - must be a resource in resources Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model). | ||||
| identifier |
ΣC | 0..1 | Identifier | Logical reference, when literal reference is not known | ||||
| display |
ΣC | 0..1 | string | Text alternative for the resource Required Pattern: Name of the medication/active inredient. Siia toimeaine nimetus | ||||
| status |
Σ | 0..1 | CodeableConcept | Whether this is a current issue or one that has been retired etc Binding: PublicationStatus (preferred): The lifecycle status of an artifact. | ||||
| interaction |
ΣC | 0..1 | BackboneElement | Specifics for when this is an interaction | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ||||
| interactant |
Σ | 0..* | BackboneElement | The specific medication, product, food etc. or laboratory test that interacts | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ||||
 item[x] |
Σ | 1..1 | The specific medication, product, food etc. or laboratory test that interacts Binding: Interactant (example): An interactant - a substance that may have a clinically significant effect on another. | |||||
| itemReference |
Reference(MedicinalProductDefinition | Medication | Substance | NutritionProduct | BiologicallyDerivedProduct | ObservationDefinition) | |||||||
| itemCodeableConcept |
CodeableConcept | |||||||
| type |
Σ | 0..1 | CodeableConcept | The type of the interaction e.g. drug-drug interaction, drug-lab test interaction Binding: InteractionType (example): A categorisation for an interaction between two substances. | ||||
| effect |
Σ | 0..1 | CodeableReference(ObservationDefinition) | The effect of the interaction, for example "reduced gastric absorption of primary medication" Binding: InteractionEffect (example): A interaction effect of clinical use of a medication or other substance. | ||||
| incidence |
Σ | 0..1 | CodeableConcept | The incidence of the interaction, e.g. theoretical, observed Binding: InteractionIncidence (example): A categorisation for incidence of occurence of an interaction. | ||||
| management |
Σ | 0..* | CodeableConcept | Actions for managing the interaction Binding: InteractionManagement (example): A type of management for an interaction of a medication or other substance. | ||||
| undesirableEffect |
ΣC | 0..1 | BackboneElement | Classification A/B/C/D and description how the dosage must be adjusted | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ||||
| symptomConditionEffect |
Σ | 0..1 | CodeableReference(ObservationDefinition) | The situation in which the undesirable effect may manifest Binding: UndesirableEffectSymptom (example): An undesirable effect of clinical use. | ||||
| classification |
Σ | 0..1 | CodeableConcept | klassifikatsioon (A/B/C/D) + selle tekst nt C, text: Annust või annustamise vahemikku tuleb kohandada Binding: UndesirableEffectClassification (example): Use this fictive system https://fhir.ee/synbase-warning-classification | ||||
| frequencyOfOccurrence |
Σ | 0..1 | CodeableConcept | How often the effect is seen Binding: UndesirablEffectFrequency (example): A categorisation for a frequency of occurence of an undesirable effect. | ||||
| warning |
ΣC | 0..1 | BackboneElement | Critical environmental, health or physical risks or hazards. For example 'Do not operate heavy machinery', 'May cause drowsiness' | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ||||
| description |
Σ | 0..1 | markdown | A textual definition of this warning, with formatting | ||||
| code |
Σ | 0..1 | CodeableConcept | A coded or unformatted textual definition of this warning Binding: WarningType (example): Classification of warning type. | ||||
| Documentation for this format | ||||||||
| Path | Status | Usage | ValueSet | Version | Source |
| ClinicalUseDefinition.language | Base | required | All Languages | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.type | Base | required | Clinical Use Definition Type | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:drugFormGroup | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:failureDegree | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:additionalInformation | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.subject.type | Base | extensible | Resource Types | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.status | Base | preferred | PublicationStatus | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.contraindication.diseaseSymptomProcedure | Base | example | Disease Symptom Procedure | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.contraindication.diseaseStatus | Base | example | Disease Status | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.contraindication.comorbidity | Base | example | Disease Symptom Procedure | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.contraindication.otherTherapy.relationshipType | Base | preferred | Therapy Relationship Type | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.contraindication.otherTherapy.treatment | Base | example | Therapy | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.indication.diseaseSymptomProcedure | Base | example | Disease Symptom Procedure | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.indication.diseaseStatus | Base | example | Disease Status | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.indication.comorbidity | Base | example | Disease Symptom Procedure | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.indication.intendedEffect | Base | preferred | Product Intended Use | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.interaction.interactant.item[x] | Base | example | Interactant | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.interaction.type | Base | example | Interaction Type | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.interaction.effect | Base | example | Interaction Effect | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.interaction.incidence | Base | example | Interaction Incidence | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.interaction.management | Base | example | Interaction Management | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.undesirableEffect.symptomConditionEffect | Base | example | Undesirable Effect Symptom | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.undesirableEffect.classification | Base | example | Undesirable Effect Classification | 📦5.0.0 | FHIR Std. |
| ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence | Base | example | Undesirabl Effect Frequency | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.warning.code | Base | example | Warning Type | 📍5.0.0 | FHIR Std. |
| Id | Grade | Path(s) | Description | Expression |
| cud-1 | error | ClinicalUseDefinition | Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot be used in the same instance |
(ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count() + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count() + ClinicalUseDefinition.warning.count()) < 2
|
| dom-2 | error | ClinicalUseDefinition | If the resource is contained in another resource, it SHALL NOT contain nested Resources |
contained.contained.empty()
|
| dom-3 | error | ClinicalUseDefinition | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource |
contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
|
| dom-4 | error | ClinicalUseDefinition | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated |
contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
|
| dom-5 | error | ClinicalUseDefinition | If a resource is contained in another resource, it SHALL NOT have a security label |
contained.meta.security.empty()
|
| dom-6 | best practice | ClinicalUseDefinition | A resource should have narrative for robust management |
text.`div`.exists()
|
| ele-1 | error | **ALL** elements | All FHIR elements must have a @value or children |
hasValue() or (children().count() > id.count())
|
| ext-1 | error | **ALL** extensions | Must have either extensions or value[x], not both |
extension.exists() != value.exists()
|
This structure is derived from ClinicalUseDefinition
Summary
Mandatory: 2 elements(3 nested mandatory elements)
Fixed: 1 element
Prohibited: 4 elements
Extensions
This structure refers to these extensions:
Slices
This structure defines the following Slices:
Key Elements View
| Name | Flags | Card. | Type | Description & Constraints Filter: |
|---|---|---|---|---|
| ClinicalUseDefinition |
C | 0..* | ClinicalUseDefinition | A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure Constraints: cud-1 |
| implicitRules |
?!Σ | 0..1 | uri | A set of rules under which this content was created |
| contained |
1..1 | Medication | Contained, inline Resources | |
| Slices for extension |
0..* | Extension | Extension Slice: Unordered, Open by value:url | |
| extension:affected |
0..* | Reference(EETISMedicationStatement) | MedicationStatements affected by interactions. URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements | |
| extension:link |
0..* | string | Additional information from external source. URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link | |
| extension:nephrotoxic |
0..* | boolean | Is the medication nephrotoxic or not. URL: https://fhir.ee/StructureDefinition/ee-tis-nephrotoxic | |
| extension:dosageModification |
0..* | (Complex) | Recommendation for dosaging URL: https://fhir.ee/StructureDefinition/ee-tis-dosage-modification | |
| extension:relatedObservation |
0..* | Reference(Observation | Condition) | Observation/Condition which triggers renal function alert. URL: https://fhir.ee/StructureDefinition/ee-tis-related-observation-or-condition | |
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored |
| type |
Σ | 1..1 | code | indication | contraindication | interaction | undesirable-effect | warning Binding: ClinicalUseDefinitionType (required): Overall defining type of this clinical use definition. Fixed Value: undesirable-effect |
| Slices for category |
Σ | 0..* | CodeableConcept | RenBase drugFormGroup ja failureDegree Slice: Unordered, Open by value:coding Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. |
| category:drugFormGroup |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. |
| coding |
Σ | 1..* | Coding | 0 | 1 | 2 | 3 | 4 | 5| This is a fake system for example. Do NOT use it! Required Pattern: At least the following |
| id |
0..1 | string | Unique id for inter-element referencing | |
| extension |
0..* | Extension | Additional content defined by implementations | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/drug-form-group | |
| version |
0..1 | string | Version of the system - if relevant | |
| code |
0..1 | code | Symbol in syntax defined by the system | |
| display |
0..1 | string | Representation defined by the system | |
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |
| category:failureDegree |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. |
| coding |
Σ | 1..* | Coding | Failure degree 0-4. Neerupuudulikkuse aste: number + selgitus. This is a fake system for example. Do NOT use it! Required Pattern: At least the following |
| id |
0..1 | string | Unique id for inter-element referencing | |
| extension |
0..* | Extension | Additional content defined by implementations | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/failure-degree | |
| version |
0..1 | string | Version of the system - if relevant | |
| code |
0..1 | code | Symbol in syntax defined by the system | |
| display |
0..1 | string | Representation defined by the system | |
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |
| category:additionalInformation |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. |
| coding |
Σ | 1..* | Coding | This is a fake system for example. Do NOT use it Required Pattern: At least the following |
| id |
0..1 | string | Unique id for inter-element referencing | |
| extension |
0..* | Extension | Additional content defined by implementations | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/additional-information | |
| version |
0..1 | string | Version of the system - if relevant | |
| code |
0..1 | code | Symbol in syntax defined by the system | |
| display |
0..1 | string | Representation defined by the system | |
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |
| subject |
Σ | 1..* | Reference(Medication) | medication that may cause renal function failure |
| reference |
ΣC | 0..1 | string | Literal reference, Relative, internal or absolute URL |
| display |
ΣC | 0..1 | string | Text alternative for the resource Required Pattern: Name of the medication/active inredient. Siia toimeaine nimetus |
| undesirableEffect |
ΣC | 0..1 | BackboneElement | Classification A/B/C/D and description how the dosage must be adjusted |
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized |
| classification |
Σ | 0..1 | CodeableConcept | klassifikatsioon (A/B/C/D) + selle tekst nt C, text: Annust või annustamise vahemikku tuleb kohandada Binding: UndesirableEffectClassification (example): Use this fictive system https://fhir.ee/synbase-warning-classification |
| Documentation for this format | ||||
| Path | Status | Usage | ValueSet | Version | Source |
| ClinicalUseDefinition.type | Base | required | Clinical Use Definition Type | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:drugFormGroup | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:failureDegree | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:additionalInformation | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.undesirableEffect.classification | Base | example | Undesirable Effect Classification | 📦5.0.0 | FHIR Std. |
| Id | Grade | Path(s) | Description | Expression |
| cud-1 | error | ClinicalUseDefinition | Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot be used in the same instance |
(ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count() + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count() + ClinicalUseDefinition.warning.count()) < 2
|
| dom-2 | error | ClinicalUseDefinition | If the resource is contained in another resource, it SHALL NOT contain nested Resources |
contained.contained.empty()
|
| dom-3 | error | ClinicalUseDefinition | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource |
contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
|
| dom-4 | error | ClinicalUseDefinition | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated |
contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
|
| dom-5 | error | ClinicalUseDefinition | If a resource is contained in another resource, it SHALL NOT have a security label |
contained.meta.security.empty()
|
| dom-6 | best practice | ClinicalUseDefinition | A resource should have narrative for robust management |
text.`div`.exists()
|
| ele-1 | error | **ALL** elements | All FHIR elements must have a @value or children |
hasValue() or (children().count() > id.count())
|
| ext-1 | error | **ALL** extensions | Must have either extensions or value[x], not both |
extension.exists() != value.exists()
|
Differential View
This structure is derived from ClinicalUseDefinition
| Name | Flags | Card. | Type | Description & Constraints Filter: |
|---|---|---|---|---|
| ClinicalUseDefinition |
ClinicalUseDefinition | |||
| contained |
1..1 | Medication | Contained, inline Resources | |
| Slices for extension |
0..* | Extension | Extension Slice: Unordered, Open by value:url | |
| extension:affected |
0..* | Reference(EETISMedicationStatement) | MedicationStatements affected by interactions. URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements | |
| extension:link |
0..* | string | Additional information from external source. URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link | |
| extension:nephrotoxic |
0..* | boolean | Is the medication nephrotoxic or not. URL: https://fhir.ee/StructureDefinition/ee-tis-nephrotoxic | |
| extension:dosageModification |
0..* | (Complex) | Recommendation for dosaging URL: https://fhir.ee/StructureDefinition/ee-tis-dosage-modification | |
| extension:relatedObservation |
0..* | Reference(Observation | Condition) | Observation/Condition which triggers renal function alert. URL: https://fhir.ee/StructureDefinition/ee-tis-related-observation-or-condition | |
| type |
1..1 | code | indication | contraindication | interaction | undesirable-effect | warning Fixed Value: undesirable-effect | |
| Slices for category |
0..* | CodeableConcept | RenBase drugFormGroup ja failureDegree Slice: Unordered, Open by value:coding | |
| category:drugFormGroup |
0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" | |
| coding |
1..* | Coding | 0 | 1 | 2 | 3 | 4 | 5| This is a fake system for example. Do NOT use it! Required Pattern: At least the following | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/drug-form-group | |
| category:failureDegree |
0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" | |
| coding |
1..* | Coding | Failure degree 0-4. Neerupuudulikkuse aste: number + selgitus. This is a fake system for example. Do NOT use it! Required Pattern: At least the following | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/failure-degree | |
| category:additionalInformation |
0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" | |
| coding |
1..* | Coding | This is a fake system for example. Do NOT use it Required Pattern: At least the following | |
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/additional-information | |
| subject |
1..* | Reference(Medication) | medication that may cause renal function failure | |
| display |
0..1 | string | Text alternative for the resource Required Pattern: Name of the medication/active inredient. Siia toimeaine nimetus | |
| contraindication |
0..0 | |||
| indication |
0..0 | |||
| population |
0..0 | |||
| library |
0..0 | |||
| undesirableEffect |
0..1 | BackboneElement | Classification A/B/C/D and description how the dosage must be adjusted | |
| classification |
0..1 | CodeableConcept | klassifikatsioon (A/B/C/D) + selle tekst nt C, text: Annust või annustamise vahemikku tuleb kohandada Binding: UndesirableEffectClassification (example): Use this fictive system https://fhir.ee/synbase-warning-classification | |
| Documentation for this format | ||||
| Path | Status | Usage | ValueSet | Version | Source |
| ClinicalUseDefinition.undesirableEffect.classification | Base | example | Undesirable Effect Classification | 📦5.0.0 | FHIR Std. |
Snapshot View
| Name | Flags | Card. | Type | Description & Constraints Filter: | ||||
|---|---|---|---|---|---|---|---|---|
| ClinicalUseDefinition |
C | 0..* | ClinicalUseDefinition | A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure Constraints: cud-1 | ||||
| id |
Σ | 0..1 | id | Logical id of this artifact | ||||
| meta |
Σ | 0..1 | Meta | Metadata about the resource | ||||
| implicitRules |
?!Σ | 0..1 | uri | A set of rules under which this content was created | ||||
| language |
0..1 | code | Language of the resource content Binding: AllLanguages (required): IETF language tag for a human language
| |||||
| text |
0..1 | Narrative | Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements | |||||
| contained |
1..1 | Medication | Contained, inline Resources | |||||
| Slices for extension |
0..* | Extension | Extension Slice: Unordered, Open by value:url | |||||
| extension:affected |
0..* | Reference(EETISMedicationStatement) | MedicationStatements affected by interactions. URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements | |||||
| extension:link |
0..* | string | Additional information from external source. URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link | |||||
| extension:nephrotoxic |
0..* | boolean | Is the medication nephrotoxic or not. URL: https://fhir.ee/StructureDefinition/ee-tis-nephrotoxic | |||||
| extension:dosageModification |
0..* | (Complex) | Recommendation for dosaging URL: https://fhir.ee/StructureDefinition/ee-tis-dosage-modification | |||||
| extension:relatedObservation |
0..* | Reference(Observation | Condition) | Observation/Condition which triggers renal function alert. URL: https://fhir.ee/StructureDefinition/ee-tis-related-observation-or-condition | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored | ||||
| identifier |
Σ | 0..* | Identifier | Business identifier for this issue | ||||
| type |
Σ | 1..1 | code | indication | contraindication | interaction | undesirable-effect | warning Binding: ClinicalUseDefinitionType (required): Overall defining type of this clinical use definition. Fixed Value: undesirable-effect | ||||
| Slices for category |
Σ | 0..* | CodeableConcept | RenBase drugFormGroup ja failureDegree Slice: Unordered, Open by value:coding Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. | ||||
| category:drugFormGroup |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. | ||||
| id |
0..1 | id | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Slice: Unordered, Open by value:url | |||||
| coding |
Σ | 1..* | Coding | 0 | 1 | 2 | 3 | 4 | 5| This is a fake system for example. Do NOT use it! Required Pattern: At least the following | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/drug-form-group | |||||
| version |
0..1 | string | Version of the system - if relevant | |||||
| code |
0..1 | code | Symbol in syntax defined by the system | |||||
| display |
0..1 | string | Representation defined by the system | |||||
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |||||
| text |
Σ | 0..1 | string | Plain text representation of the concept | ||||
| category:failureDegree |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. | ||||
| id |
0..1 | id | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Slice: Unordered, Open by value:url | |||||
| coding |
Σ | 1..* | Coding | Failure degree 0-4. Neerupuudulikkuse aste: number + selgitus. This is a fake system for example. Do NOT use it! Required Pattern: At least the following | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/failure-degree | |||||
| version |
0..1 | string | Version of the system - if relevant | |||||
| code |
0..1 | code | Symbol in syntax defined by the system | |||||
| display |
0..1 | string | Representation defined by the system | |||||
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |||||
| text |
Σ | 0..1 | string | Plain text representation of the concept | ||||
| category:additionalInformation |
Σ | 0..1 | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item. | ||||
| id |
0..1 | id | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Slice: Unordered, Open by value:url | |||||
| coding |
Σ | 1..* | Coding | This is a fake system for example. Do NOT use it Required Pattern: At least the following | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| system |
1..1 | uri | Identity of the terminology system Fixed Value: https://fhir.ee/additional-information | |||||
| version |
0..1 | string | Version of the system - if relevant | |||||
| code |
0..1 | code | Symbol in syntax defined by the system | |||||
| display |
0..1 | string | Representation defined by the system | |||||
| userSelected |
0..1 | boolean | If this coding was chosen directly by the user | |||||
| text |
Σ | 0..1 | string | Plain text representation of the concept | ||||
| subject |
Σ | 1..* | Reference(Medication) | medication that may cause renal function failure | ||||
| id |
0..1 | id | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations Slice: Unordered, Open by value:url | |||||
| reference |
ΣC | 0..1 | string | Literal reference, Relative, internal or absolute URL | ||||
| type |
Σ | 0..1 | uri | Type the reference refers to (e.g. "Patient") - must be a resource in resources Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model). | ||||
| identifier |
ΣC | 0..1 | Identifier | Logical reference, when literal reference is not known | ||||
| display |
ΣC | 0..1 | string | Text alternative for the resource Required Pattern: Name of the medication/active inredient. Siia toimeaine nimetus | ||||
| status |
Σ | 0..1 | CodeableConcept | Whether this is a current issue or one that has been retired etc Binding: PublicationStatus (preferred): The lifecycle status of an artifact. | ||||
| interaction |
ΣC | 0..1 | BackboneElement | Specifics for when this is an interaction | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ||||
| interactant |
Σ | 0..* | BackboneElement | The specific medication, product, food etc. or laboratory test that interacts | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ||||
| item[x] |
Σ | 1..1 | The specific medication, product, food etc. or laboratory test that interacts Binding: Interactant (example): An interactant - a substance that may have a clinically significant effect on another. | |||||
| itemReference |
Reference(MedicinalProductDefinition | Medication | Substance | NutritionProduct | BiologicallyDerivedProduct | ObservationDefinition) | |||||||
| itemCodeableConcept |
CodeableConcept | |||||||
| type |
Σ | 0..1 | CodeableConcept | The type of the interaction e.g. drug-drug interaction, drug-lab test interaction Binding: InteractionType (example): A categorisation for an interaction between two substances. | ||||
| effect |
Σ | 0..1 | CodeableReference(ObservationDefinition) | The effect of the interaction, for example "reduced gastric absorption of primary medication" Binding: InteractionEffect (example): A interaction effect of clinical use of a medication or other substance. | ||||
| incidence |
Σ | 0..1 | CodeableConcept | The incidence of the interaction, e.g. theoretical, observed Binding: InteractionIncidence (example): A categorisation for incidence of occurence of an interaction. | ||||
| management |
Σ | 0..* | CodeableConcept | Actions for managing the interaction Binding: InteractionManagement (example): A type of management for an interaction of a medication or other substance. | ||||
| undesirableEffect |
ΣC | 0..1 | BackboneElement | Classification A/B/C/D and description how the dosage must be adjusted | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ||||
| symptomConditionEffect |
Σ | 0..1 | CodeableReference(ObservationDefinition) | The situation in which the undesirable effect may manifest Binding: UndesirableEffectSymptom (example): An undesirable effect of clinical use. | ||||
| classification |
Σ | 0..1 | CodeableConcept | klassifikatsioon (A/B/C/D) + selle tekst nt C, text: Annust või annustamise vahemikku tuleb kohandada Binding: UndesirableEffectClassification (example): Use this fictive system https://fhir.ee/synbase-warning-classification | ||||
| frequencyOfOccurrence |
Σ | 0..1 | CodeableConcept | How often the effect is seen Binding: UndesirablEffectFrequency (example): A categorisation for a frequency of occurence of an undesirable effect. | ||||
| warning |
ΣC | 0..1 | BackboneElement | Critical environmental, health or physical risks or hazards. For example 'Do not operate heavy machinery', 'May cause drowsiness' | ||||
| id |
0..1 | string | Unique id for inter-element referencing | |||||
| extension |
0..* | Extension | Additional content defined by implementations | |||||
| modifierExtension |
?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ||||
| description |
Σ | 0..1 | markdown | A textual definition of this warning, with formatting | ||||
| code |
Σ | 0..1 | CodeableConcept | A coded or unformatted textual definition of this warning Binding: WarningType (example): Classification of warning type. | ||||
| Documentation for this format | ||||||||
| Path | Status | Usage | ValueSet | Version | Source |
| ClinicalUseDefinition.language | Base | required | All Languages | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.type | Base | required | Clinical Use Definition Type | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:drugFormGroup | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:failureDegree | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.category:additionalInformation | Base | preferred | Clinical Use Definition Category | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.subject.type | Base | extensible | Resource Types | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.status | Base | preferred | PublicationStatus | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.contraindication.diseaseSymptomProcedure | Base | example | Disease Symptom Procedure | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.contraindication.diseaseStatus | Base | example | Disease Status | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.contraindication.comorbidity | Base | example | Disease Symptom Procedure | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.contraindication.otherTherapy.relationshipType | Base | preferred | Therapy Relationship Type | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.contraindication.otherTherapy.treatment | Base | example | Therapy | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.indication.diseaseSymptomProcedure | Base | example | Disease Symptom Procedure | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.indication.diseaseStatus | Base | example | Disease Status | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.indication.comorbidity | Base | example | Disease Symptom Procedure | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.indication.intendedEffect | Base | preferred | Product Intended Use | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.interaction.interactant.item[x] | Base | example | Interactant | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.interaction.type | Base | example | Interaction Type | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.interaction.effect | Base | example | Interaction Effect | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.interaction.incidence | Base | example | Interaction Incidence | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.interaction.management | Base | example | Interaction Management | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.undesirableEffect.symptomConditionEffect | Base | example | Undesirable Effect Symptom | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.undesirableEffect.classification | Base | example | Undesirable Effect Classification | 📦5.0.0 | FHIR Std. |
| ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence | Base | example | Undesirabl Effect Frequency | 📍5.0.0 | FHIR Std. |
| ClinicalUseDefinition.warning.code | Base | example | Warning Type | 📍5.0.0 | FHIR Std. |
| Id | Grade | Path(s) | Description | Expression |
| cud-1 | error | ClinicalUseDefinition | Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot be used in the same instance |
(ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count() + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count() + ClinicalUseDefinition.warning.count()) < 2
|
| dom-2 | error | ClinicalUseDefinition | If the resource is contained in another resource, it SHALL NOT contain nested Resources |
contained.contained.empty()
|
| dom-3 | error | ClinicalUseDefinition | If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource |
contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
|
| dom-4 | error | ClinicalUseDefinition | If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated |
contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
|
| dom-5 | error | ClinicalUseDefinition | If a resource is contained in another resource, it SHALL NOT have a security label |
contained.meta.security.empty()
|
| dom-6 | best practice | ClinicalUseDefinition | A resource should have narrative for robust management |
text.`div`.exists()
|
| ele-1 | error | **ALL** elements | All FHIR elements must have a @value or children |
hasValue() or (children().count() > id.count())
|
| ext-1 | error | **ALL** extensions | Must have either extensions or value[x], not both |
extension.exists() != value.exists()
|
This structure is derived from ClinicalUseDefinition
Summary
Mandatory: 2 elements(3 nested mandatory elements)
Fixed: 1 element
Prohibited: 4 elements
Extensions
This structure refers to these extensions:
Slices
This structure defines the following Slices:
Other representations of profile: CSV, Excel, Schematron