Medication Scheme Implementation Guide
1.0.0 - draft
Medication Scheme Implementation Guide
1.0.0 - draft
Medication Scheme Implementation Guide, published by TEHIK. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/TEHIK-EE/ig-ee-medication-scheme/ and changes regularly. See the Directory of published versions
{
"resourceType" : "ClinicalUseDefinition",
"id" : "renal-function-failure",
"meta" : {
"profile" : [
🔗 "https://fhir.ee/StructureDefinition/ee-tis-renal-failure-ds"
]
},
"language" : "et",
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\" xml:lang=\"et\" lang=\"et\"><p class=\"res-header-id\"><b>Generated Narrative: ClinicalUseDefinition renal-function-failure</b></p><a name=\"renal-function-failure\"> </a><a name=\"hcrenal-function-failure\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Language: et</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ee-tis-renal-failure-ds.html\">EETISRenalFailureDS</a></p></div><p><b>ExtensionEETISAffectedMedicationStatements</b>: <a href=\"MedicationStatement-MedicationStatement-metformin.html\">MedicationStatement: extension = ,100,2023-11-07,,,Avalik,order,; status = recorded; category = Pidev,Tavaretsept,3-kordne; effective[x] = 2015-02-07 13:28:17-0500 --> (ongoing); note = patsient peaks iga päev veresuhkrut mõõtma</a></p><p><b>ExtensionEETISAdditionalInformationLink</b>: www.synbase.ee/metformin-neerufunktsioon</p><p><b>ExtensionEETISNephrotoxic</b>: false</p><blockquote><p><b>ExtensionEETISDosageModification</b></p><ul><li>dosageIntervalMin: 6</li><li>dosageIntervalMax: 12</li><li>recommendation: Siin on soovitused</li></ul></blockquote><p><b>ExtensionEETISRelatedObservationOrCondition</b>: <a href=\"Observation-observation-egfr1.html\">Observation 62238-1</a></p><p><b>type</b>: Undesirable Effect</p><p><b>category</b>: <span title=\"Codes:{https://fhir.ee/drug-form-group 2}\">Kirjeldus siia text alla, kui on veel vaja midagi lisada</span>, <span title=\"Codes:{https://fhir.ee/failure-degree 1}\">Kirjeldus siia text alla, kui on veel vaja midagi lisada</span>, <span title=\"Codes:\">Kuna vosoritiidi ohutust ja efektiivsust neerukahjustuse korral ei ole hinnatud [(1)],[(2)], ei saa tõenduspõhiseid soovitusi anda. Siiski, tuginedes eliminatsioonimehhanismile, ei mõjuta neerupuudulikkus ilmselt vosoritiidi farmakokineetikat. Vosoritiid on modifitseeritud C-tüüpi natriureetiline peptiid. Vosoritiidi metabolism toimub eeldatavasti kataboolsete radade kaudu ja laguneb väikesteks peptiidideks ja aminohapeteks [(1)], [(2)].</span></p><p><b>subject</b>: <a href=\"#hcrenal-function-failure/metformin\">Medication: extension = metformiin; identifier = https://fhir.ee/CodeSystem/tis-fhir-identifikaatorid#ravimiregister-pakend#123456; doseForm = tablett+õhukese polümeerikattega tablett; totalVolume = 120</a></p><p><b>status</b>: <span title=\"Codes:\">active</span></p><h3>UndesirableEffects</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Classification</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{https://fhir.ee/synbase-warning-classification C}\">Kui on veel vaja midagi lisada</span></td></tr></table><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Medication #metformin</b></p><a name=\"renal-function-failure/metformin\"> </a><a name=\"hcrenal-function-failure/metformin\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Language: et</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ee-tis-medication-epc.html\">EETISMedicationEPC</a></p></div><p><b>ExtensionEETISMedicinalProductClassification</b>: <span title=\"Codes:{https://fhir.ee/CodeSystem/atc-ee A10BA02}\">metformiin</span></p><p><b>identifier</b>: <code>https://fhir.ee/CodeSystem/tis-fhir-identifikaatorid#ravimiregister-pakend</code>/123456</p><p><b>doseForm</b>: <span title=\"Codes:{https://fhir.ee/CodeSystem/ravimvormid 1518}\">tablett+õhukese polümeerikattega tablett</span></p><p><b>totalVolume</b>: 120</p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{https://fhir.ee/CodeSystem/toimeained 11354}\">metformiin</span></td></tr></table><p><b>isActive</b>: true</p><p><b>strength</b>: 500(unit MG from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: retsept-mahu-ja-massiyhik codeMG = 'MG')</span>/1(unit TABL from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: retsept-mahu-ja-massiyhik codeTABL = 'TABLETTI')</span></p></blockquote></blockquote></div>"
},
"contained" : [
{
"resourceType" : "Medication",
"id" : "metformin",
"meta" : {
"profile" : [
🔗 "https://fhir.ee/StructureDefinition/ee-tis-medication-epc"
]
},
"language" : "et",
"extension" : [
{
"url" : "https://fhir.ee/StructureDefinition/ee-tis-medicinal-product-classification",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "https://fhir.ee/CodeSystem/atc-ee",
"code" : "A10BA02",
"display" : "metformiin"
}
]
}
}
],
"identifier" : [
{
"system" : "https://fhir.ee/CodeSystem/tis-fhir-identifikaatorid#ravimiregister-pakend",
"value" : "123456"
}
],
"doseForm" : {
"coding" : [
{
"system" : "https://fhir.ee/CodeSystem/ravimvormid",
"code" : "1518",
"display" : "tablett+õhukese polümeerikattega tablett"
}
]
},
"totalVolume" : {
"value" : 120
},
"ingredient" : [
{
"item" : {
"concept" : {
"coding" : [
{
"system" : "https://fhir.ee/CodeSystem/toimeained",
"code" : "11354",
"display" : "metformiin"
}
]
}
},
"isActive" : true,
"strengthRatio" : {
"numerator" : {
"value" : 500,
"system" : "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik",
"code" : "MG"
},
"denominator" : {
"value" : 1,
"system" : "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik",
"code" : "TABL"
}
}
}
]
}
],
"extension" : [
{
"url" : "https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements",
"valueReference" : {
🔗 "reference" : "MedicationStatement/MedicationStatement-metformin"
}
},
{
"url" : "https://fhir.ee/StructureDefinition/ee-tis-additional-information-link",
"valueString" : "www.synbase.ee/metformin-neerufunktsioon"
},
{
"url" : "https://fhir.ee/StructureDefinition/ee-tis-nephrotoxic",
"valueBoolean" : false
},
{
"extension" : [
{
"url" : "dosageIntervalMin",
"valueQuantity" : {
"value" : 6
}
},
{
"url" : "dosageIntervalMax",
"valueQuantity" : {
"value" : 12
}
},
{
"url" : "recommendation",
"valueString" : "Siin on soovitused"
}
],
"url" : "https://fhir.ee/StructureDefinition/ee-tis-dosage-modification"
},
{
"url" : "https://fhir.ee/StructureDefinition/ee-tis-related-observation-or-condition",
"valueReference" : {
🔗 "reference" : "Observation/observation-egfr1"
}
}
],
"type" : "undesirable-effect",
"category" : [
{
"coding" : [
{
"system" : "https://fhir.ee/drug-form-group",
"code" : "2",
"display" : "süsteemne"
}
],
"text" : "Kirjeldus siia text alla, kui on veel vaja midagi lisada"
},
{
"coding" : [
{
"system" : "https://fhir.ee/failure-degree",
"code" : "1",
"display" : "GFR 30-59 ml/min (mõõdukas neerupuudulikkus)"
}
],
"text" : "Kirjeldus siia text alla, kui on veel vaja midagi lisada"
},
{
"text" : "Kuna vosoritiidi ohutust ja efektiivsust neerukahjustuse korral ei ole hinnatud [(1)],[(2)], ei saa tõenduspõhiseid soovitusi anda. Siiski, tuginedes eliminatsioonimehhanismile, ei mõjuta neerupuudulikkus ilmselt vosoritiidi farmakokineetikat. Vosoritiid on modifitseeritud C-tüüpi natriureetiline peptiid. Vosoritiidi metabolism toimub eeldatavasti kataboolsete radade kaudu ja laguneb väikesteks peptiidideks ja aminohapeteks [(1)], [(2)]."
}
],
"subject" : [
{
"reference" : "#metformin"
}
],
"status" : {
"coding" : [
{
"code" : "active"
}
]
},
"undesirableEffect" : {
"classification" : {
"coding" : [
{
"system" : "https://fhir.ee/synbase-warning-classification",
"code" : "C",
"display" : "Annust või annustamise vahemikku tuleb kohandada"
}
],
"text" : "Kui on veel vaja midagi lisada"
}
}
}