Medication Scheme Implementation Guide
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Medication Scheme Implementation Guide, published by TEHIK. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/TEHIK-EE/ig-ee-medication-scheme/ and changes regularly. See the Directory of published versions

: medication-interaction1 - JSON Representation

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{
  "resourceType" : "ClinicalUseDefinition",
  "id" : "medication-interaction1",
  "meta" : {
    "profile" : [
      🔗 "https://fhir.ee/StructureDefinition/ee-tis-medication-interaction"
    ]
  },
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ClinicalUseDefinition medication-interaction1</b></p><a name=\"medication-interaction1\"> </a><a name=\"hcmedication-interaction1\"> </a><a name=\"medication-interaction1-en-US\"> </a><p><b>ExtensionEETISAffectedMedicationStatements</b>: <a href=\"MedicationStatement-MedicationStatement-metformin.html\">MedicationStatement: extension = ,100,2023-11-07,,,Avalik,order,; status = recorded; category = Pidev,ei ole patsiendi ytluse põhjal,tavaretsept,3-kordne; effective[x] = 2015-02-07 13:28:17-0500 --&gt; (ongoing); note = patsient peaks iga päev veresuhkrut mõõtma</a></p><p><b>ExtensionEETISAffectedMedicationStatements</b>: <a href=\"MedicationStatement-MedicationStatementAdrenalin.html\">MedicationStatement: extension = ,5,2023-11-07,,,,,Privaatne,order,; status = recorded; category = Ühekordne,ei ole patsiendi ytluse põhjal,tavaretsept,1-kordne; effective[x] = 2015-02-07 13:28:17-0500 --&gt; (ongoing); note = lõpuks ometi sai müügiloataotlus rahuldatud ja saab ravimit tellida</a></p><p><b>ExtensionEETISAdditionalInformationLink</b>: www.synbase.ee/metformin+adrenalin</p><p><b>type</b>: Interaction</p><p><b>subject</b>: <a href=\"#hcmedication-interaction1/metformin\">Medication: extension = metformiin; doseForm = tablett+õhukese polümeerikattega tablett; totalVolume = 120</a></p><p><b>status</b>: <span title=\"Codes:\">active</span></p><blockquote><p><b>interaction</b></p><h3>Interactants</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Item[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"#hcmedication-interaction1/adrenalin\">Medication: extension = Epinefriin,1 ML,Adrenaliin; doseForm = süstelahus; totalVolume = 5</a></td></tr></table><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/interaction-type drug-drug}\">drug to drug interaction</span></p><h3>Effects</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">Consequences. Ravim A vererõhku alandav ja diureetiline toime võib ravim B-ga kooskasutamisel nõrgeneda ning suurendada kehakaalu. Vererõhk kõrgeneb enamasti vähe või mõõdukalt, kuid hüpertensiooni tüsistuste tekke oht võib suureneda, eriti eakatel.</span></td></tr></table><p><b>incidence</b>: <span title=\"Codes:\">D0</span></p><p><b>management</b>: <span title=\"Codes:\">Recommendation. Kui kooskasutamine on vajalik, on soovitatav hoolikalt jälgida vererõhku ja kehakaalu. Ravimi A annust võib olla vaja kohandada. Kaaluda raviks xxx, kuna Ravim B ei vähenda toimet.</span></p></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Medication  #metformin</b></p><a name=\"medication-interaction1/metformin\"> </a><a name=\"hcmedication-interaction1/metformin\"> </a><a name=\"medication-interaction1/metformin-en-US\"> </a><p><b>ExtensionEETISMedicinalProductClassification</b>: <span title=\"Codes:{https://fhir.ee/CodeSystem/atc-ee A10BA02}\">metformiin</span></p><p><b>doseForm</b>: <span title=\"Codes:{https://fhir.ee/CodeSystem/ravimvormid 1518}\">tablett+õhukese polümeerikattega tablett</span></p><p><b>totalVolume</b>: 120</p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{https://fhir.ee/CodeSystem/toimeained 11354}\">metformiin</span></td></tr></table><p><b>isActive</b>: true</p><p><b>strength</b>: 500(unit MG from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: ER_Ühikud mahu- ja massiühikud  codeMG = 'milligram(s)')</span>/1(unit TABL from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: ER_Ühikud mahu- ja massiühikud  codeTABL = 'tablet(s)')</span></p></blockquote></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Medication  #adrenalin</b></p><a name=\"medication-interaction1/adrenalin\"> </a><a name=\"hcmedication-interaction1/adrenalin\"> </a><a name=\"medication-interaction1/adrenalin-en-US\"> </a><p><b>ExtensionEETISMedicinalProductClassification</b>: <span title=\"Codes:{https://fhir.ee/CodeSystem/atc-ee C01CA24}\">Epinefriin</span></p><p><b>ExtensionEETISSizeOfItem</b>: 1(unit ML from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: ER_Ühikud mahu- ja massiühikud  codeML = 'milliliter(s)')</span></p><p><b>ExtensionEETISMedicinalProductName</b>: Adrenaliin</p><p><b>doseForm</b>: <span title=\"Codes:{https://fhir.ee/CodeSystem/ravimvormid 739}\">süstelahus</span></p><p><b>totalVolume</b>: 5</p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{https://fhir.ee/CodeSystem/toimeained 8554}\">epinefriin</span></td></tr></table><p><b>isActive</b>: true</p><p><b>strength</b>: 1(unit MG from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: ER_Ühikud mahu- ja massiühikud  codeMG = 'milligram(s)')</span>/1(unit ML from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: ER_Ühikud mahu- ja massiühikud  codeML = 'milliliter(s)')</span></p></blockquote></blockquote></div>"
  },
  "contained" : [
    {
      "resourceType" : "Medication",
      "id" : "metformin",
      "meta" : {
        "profile" : [
          🔗 "https://fhir.ee/StructureDefinition/ee-tis-medication-epc"
        ]
      },
      "extension" : [
        {
          "url" : "https://fhir.ee/StructureDefinition/ee-tis-medicinal-product-classification",
          "valueCodeableConcept" : {
            "coding" : [
              {
                "system" : "https://fhir.ee/CodeSystem/atc-ee",
                "code" : "A10BA02",
                "display" : "metformiin"
              }
            ]
          }
        }
      ],
      "doseForm" : {
        "coding" : [
          {
            "system" : "https://fhir.ee/CodeSystem/ravimvormid",
            "code" : "1518",
            "display" : "tablett+õhukese polümeerikattega tablett"
          }
        ]
      },
      "totalVolume" : {
        "value" : 120
      },
      "ingredient" : [
        {
          "item" : {
            "concept" : {
              "coding" : [
                {
                  "system" : "https://fhir.ee/CodeSystem/toimeained",
                  "code" : "11354",
                  "display" : "metformiin"
                }
              ]
            }
          },
          "isActive" : true,
          "strengthRatio" : {
            "numerator" : {
              "value" : 500,
              "system" : "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik",
              "code" : "MG"
            },
            "denominator" : {
              "value" : 1,
              "system" : "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik",
              "code" : "TABL"
            }
          }
        }
      ]
    },
    {
      "resourceType" : "Medication",
      "id" : "adrenalin",
      "meta" : {
        "profile" : [
          🔗 "https://fhir.ee/StructureDefinition/ee-tis-medication-epc"
        ]
      },
      "extension" : [
        {
          "url" : "https://fhir.ee/StructureDefinition/ee-tis-medicinal-product-classification",
          "valueCodeableConcept" : {
            "coding" : [
              {
                "system" : "https://fhir.ee/CodeSystem/atc-ee",
                "code" : "C01CA24",
                "display" : "Epinefriin"
              }
            ]
          }
        },
        {
          "url" : "https://fhir.ee/StructureDefinition/ee-tis-size-of-item",
          "valueQuantity" : {
            "value" : 1,
            "system" : "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik",
            "code" : "ML"
          }
        },
        {
          "url" : "https://fhir.ee/StructureDefinition/ee-tis-medicinal-product-name",
          "valueString" : "Adrenaliin"
        }
      ],
      "doseForm" : {
        "coding" : [
          {
            "system" : "https://fhir.ee/CodeSystem/ravimvormid",
            "code" : "739",
            "display" : "süstelahus"
          }
        ]
      },
      "totalVolume" : {
        "value" : 5
      },
      "ingredient" : [
        {
          "item" : {
            "concept" : {
              "coding" : [
                {
                  "system" : "https://fhir.ee/CodeSystem/toimeained",
                  "code" : "8554",
                  "display" : "epinefriin"
                }
              ]
            }
          },
          "isActive" : true,
          "strengthRatio" : {
            "numerator" : {
              "value" : 1,
              "system" : "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik",
              "code" : "MG"
            },
            "denominator" : {
              "value" : 1,
              "system" : "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik",
              "code" : "ML"
            }
          }
        }
      ]
    }
  ],
  "extension" : [
    {
      "url" : "https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements",
      "valueReference" : {
        🔗 "reference" : "MedicationStatement/MedicationStatement-metformin"
      }
    },
    {
      "url" : "https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements",
      "valueReference" : {
        🔗 "reference" : "MedicationStatement/MedicationStatementAdrenalin"
      }
    },
    {
      "url" : "https://fhir.ee/StructureDefinition/ee-tis-additional-information-link",
      "valueString" : "www.synbase.ee/metformin+adrenalin"
    }
  ],
  "type" : "interaction",
  "subject" : [
    {
      "reference" : "#metformin"
    }
  ],
  "status" : {
    "coding" : [
      {
        "code" : "active"
      }
    ]
  },
  "interaction" : {
    "interactant" : [
      {
        "itemReference" : {
          "reference" : "#adrenalin"
        }
      }
    ],
    "type" : {
      "coding" : [
        {
          "system" : "http://hl7.org/fhir/interaction-type",
          "code" : "drug-drug",
          "display" : "drug to drug interaction"
        }
      ],
      "text" : "drug to drug interaction"
    },
    "effect" : {
      "concept" : {
        "text" : "Consequences. Ravim A vererõhku alandav ja diureetiline toime võib ravim B-ga kooskasutamisel nõrgeneda ning suurendada kehakaalu. Vererõhk kõrgeneb enamasti vähe või mõõdukalt, kuid hüpertensiooni tüsistuste tekke oht võib suureneda, eriti eakatel."
      }
    },
    "incidence" : {
      "text" : "D0"
    },
    "management" : [
      {
        "text" : "Recommendation. Kui kooskasutamine on vajalik, on soovitatav hoolikalt jälgida vererõhku ja kehakaalu. Ravimi A annust võib olla vaja kohandada. Kaaluda raviks xxx, kuna Ravim B ei vähenda toimet."
      }
    ]
  }
}