Medication Scheme Implementation Guide
1.0.0 - draft Estonia flag

Medication Scheme Implementation Guide, published by TEHIK. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/TEHIK-EE/ig-ee-medication-scheme/ and changes regularly. See the Directory of published versions

Resource Profile: EETISMedicationInteraction

Official URL: https://fhir.ee/StructureDefinition/ee-tis-medication-interaction Version: 1.0.0
Draft as of 2024-02-22 Computable Name: EETISMedicationInteraction

Ravimite omavahelised koostoimed. This profile is for the representation of the interactions between medication A and medication B in order to display warnings related to medications.

Usages:

You can also check for usages in the FHIR IG Statistics

Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

NameFlagsCard.TypeDescription & Constraints    Filter: Filtersdoco
.. ClinicalUseDefinition C 0..* ClinicalUseDefinition A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure
Constraints: cud-1
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... contained 2..2 Medication Contained, inline Resources
... Slices for extension 0..* Extension Extension
Slice: Unordered, Open by value:url
.... extension:affected 0..* Reference(EETISMedicationStatement) MedicationStatements affected by interactions.
URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements
.... extension:link 0..* string Additional information from external source.
URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link
... type Σ 1..1 code indication | contraindication | interaction | undesirable-effect | warning
Binding: ClinicalUseDefinitionType (required): Overall defining type of this clinical use definition.
Fixed Value: interaction
... subject Σ 1..* Reference(Medication) medication A
.... reference ΣC 0..1 string Literal reference, Relative, internal or absolute URL
.... display ΣC 0..1 string Text alternative for the resource
Required Pattern: siia toimeaine nimetus

doco Documentation for this format

Terminology Bindings

Path Status Usage ValueSet Version Source
ClinicalUseDefinition.​type Base required Clinical Use Definition Type 📍5.0.0 FHIR Std.

Constraints

Id Grade Path(s) Description Expression
cud-1 error ClinicalUseDefinition Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot be used in the same instance (ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count() + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count() + ClinicalUseDefinition.warning.count()) < 2
dom-2 error ClinicalUseDefinition If the resource is contained in another resource, it SHALL NOT contain nested Resources contained.contained.empty()
dom-3 error ClinicalUseDefinition If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4 error ClinicalUseDefinition If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5 error ClinicalUseDefinition If a resource is contained in another resource, it SHALL NOT have a security label contained.meta.security.empty()
dom-6 best practice ClinicalUseDefinition A resource should have narrative for robust management text.`div`.exists()
ele-1 error **ALL** elements All FHIR elements must have a @value or children hasValue() or (children().count() > id.count())
ext-1 error **ALL** extensions Must have either extensions or value[x], not both extension.exists() != value.exists()

This structure is derived from ClinicalUseDefinition

NameFlagsCard.TypeDescription & Constraints    Filter: Filtersdoco
.. ClinicalUseDefinition 0..* ClinicalUseDefinition A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure
... contained 2..2 Medication Contained, inline Resources
... Slices for extension 0..* Extension Extension
Slice: Unordered, Open by value:url
.... extension:affected 0..* Reference(EETISMedicationStatement) MedicationStatements affected by interactions.
URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements
.... extension:link 0..* string Additional information from external source.
URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link
... type 1..1 code indication | contraindication | interaction | undesirable-effect | warning
Fixed Value: interaction
.... display 0..1 string Text alternative for the resource
Required Pattern: siia toimeaine nimetus
... contraindication 0..0 Specifics for when this is a contraindication
... indication 0..0 Specifics for when this is an indication
... interaction
.... interactant
..... item[x] 1..1 Reference(Medication) medication B
.... type 0..1 CodeableConcept The type of the interaction e.g. drug-drug interaction, drug-lab test interaction
Fixed Value: As shown
..... coding 1..1 Coding Code defined by a terminology system
Fixed Value: (Complex)
...... system 1..1 uri Identity of the terminology system
Fixed Value: http://hl7.org/fhir/interaction-type
...... code 1..1 code Symbol in syntax defined by the system
Fixed Value: drug-drug
...... display 1..1 string Representation defined by the system
Fixed Value: drug to drug interaction
..... text 1..1 string Plain text representation of the concept
Fixed Value: drug to drug interaction
.... effect 0..1 CodeableReference(ObservationDefinition) Consequences (SYNBASE)
..... concept 0..1 CodeableConcept Consequences
...... text 0..1 string If not codeable, use text to represent consequenses
..... reference 0..0 Reference to a resource (by instance)
.... incidence 0..1 CodeableConcept Classification (SYNBASE. e.g. D0)
..... text 0..1 string Classification
.... management 0..1 CodeableConcept Recommendation (SYNBASE)
..... text 0..1 string If not codeable, use text to represent recommendation
... population 0..0 The population group to which this applies
... library 0..0 Logic used by the clinical use definition
... undesirableEffect 0..0 A possible negative outcome from the use of this treatment
... warning 0..0 Critical environmental, health or physical risks or hazards. For example 'Do not operate heavy machinery', 'May cause drowsiness'

doco Documentation for this format
NameFlagsCard.TypeDescription & Constraints    Filter: Filtersdoco
.. ClinicalUseDefinition C 0..* ClinicalUseDefinition A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure
Constraints: cud-1
... id Σ 0..1 id Logical id of this artifact
... meta Σ 0..1 Meta Metadata about the resource
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... text 0..1 Narrative Text summary of the resource, for human interpretation
This profile does not constrain the narrative in regard to content, language, or traceability to data elements
... contained 2..2 Medication Contained, inline Resources
... Slices for extension 0..* Extension Extension
Slice: Unordered, Open by value:url
.... extension:affected 0..* Reference(EETISMedicationStatement) MedicationStatements affected by interactions.
URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements
.... extension:link 0..* string Additional information from external source.
URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... identifier Σ 0..* Identifier Business identifier for this issue
... type Σ 1..1 code indication | contraindication | interaction | undesirable-effect | warning
Binding: ClinicalUseDefinitionType (required): Overall defining type of this clinical use definition.
Fixed Value: interaction
... category Σ 0..* CodeableConcept A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose"
Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item.
... subject Σ 1..* Reference(Medication) medication A
.... id 0..1 id Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
.... reference ΣC 0..1 string Literal reference, Relative, internal or absolute URL
.... type Σ 0..1 uri Type the reference refers to (e.g. "Patient") - must be a resource in resources
Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
.... identifier ΣC 0..1 Identifier Logical reference, when literal reference is not known
.... display ΣC 0..1 string Text alternative for the resource
Required Pattern: siia toimeaine nimetus
... status Σ 0..1 CodeableConcept Whether this is a current issue or one that has been retired etc
Binding: PublicationStatus (preferred): The lifecycle status of an artifact.
... interaction ΣC 0..1 BackboneElement Specifics for when this is an interaction
.... id 0..1 string Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
.... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... interactant Σ 0..* BackboneElement The specific medication, product, food etc. or laboratory test that interacts
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... item[x] Σ 1..1 Reference(Medication) medication B
.... type Σ 0..1 CodeableConcept The type of the interaction e.g. drug-drug interaction, drug-lab test interaction
Binding: InteractionType (example): A categorisation for an interaction between two substances.
Fixed Value: As shown
..... id 0..0 string Unique id for inter-element referencing
..... extension 0..0 Extension Additional content defined by implementations
..... coding 1..1 Coding Code defined by a terminology system
Fixed Value: (Complex)
...... id 0..0 string Unique id for inter-element referencing
...... extension 0..0 Extension Additional content defined by implementations
...... system 1..1 uri Identity of the terminology system
Fixed Value: http://hl7.org/fhir/interaction-type
...... version 0..0 string Version of the system - if relevant
...... code 1..1 code Symbol in syntax defined by the system
Fixed Value: drug-drug
...... display 1..1 string Representation defined by the system
Fixed Value: drug to drug interaction
...... userSelected 0..0 boolean If this coding was chosen directly by the user
..... text 1..1 string Plain text representation of the concept
Fixed Value: drug to drug interaction
.... effect Σ 0..1 CodeableReference(ObservationDefinition) Consequences (SYNBASE)
Binding: InteractionEffect (example): A interaction effect of clinical use of a medication or other substance.
..... id 0..1 id Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
..... concept Σ 0..1 CodeableConcept Consequences
...... id 0..1 id Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
...... coding Σ 0..* Coding Code defined by a terminology system
...... text Σ 0..1 string If not codeable, use text to represent consequenses
.... incidence Σ 0..1 CodeableConcept Classification (SYNBASE. e.g. D0)
Binding: InteractionIncidence (example): A categorisation for incidence of occurence of an interaction.
..... id 0..1 id Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
..... coding Σ 0..* Coding Code defined by a terminology system
..... text Σ 0..1 string Classification
.... management Σ 0..1 CodeableConcept Recommendation (SYNBASE)
Binding: InteractionManagement (example): A type of management for an interaction of a medication or other substance.
..... id 0..1 id Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
..... coding Σ 0..* Coding Code defined by a terminology system
..... text Σ 0..1 string If not codeable, use text to represent recommendation

doco Documentation for this format

Terminology Bindings

Path Status Usage ValueSet Version Source
ClinicalUseDefinition.​language Base required All Languages 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​type Base required Clinical Use Definition Type 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​category Base preferred Clinical Use Definition Category 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​subject.type Base extensible Resource Types 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​status Base preferred PublicationStatus 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​contraindication.diseaseSymptomProcedure Base example Disease Symptom Procedure 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​contraindication.diseaseStatus Base example Disease Status 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​contraindication.comorbidity Base example Disease Symptom Procedure 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​contraindication.otherTherapy.​relationshipType Base preferred Therapy Relationship Type 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​contraindication.otherTherapy.​treatment Base example Therapy 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​indication.diseaseSymptomProcedure Base example Disease Symptom Procedure 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​indication.diseaseStatus Base example Disease Status 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​indication.comorbidity Base example Disease Symptom Procedure 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​indication.intendedEffect Base preferred Product Intended Use 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​interaction.type Base example Interaction Type 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​interaction.effect Base example Interaction Effect 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​interaction.incidence Base example Interaction Incidence 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​interaction.management Base example Interaction Management 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​undesirableEffect.symptomConditionEffect Base example Undesirable Effect Symptom 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​undesirableEffect.classification Base example Undesirable Effect Classification 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​undesirableEffect.frequencyOfOccurrence Base example Undesirabl Effect Frequency 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​warning.code Base example Warning Type 📍5.0.0 FHIR Std.

Constraints

Id Grade Path(s) Description Expression
cud-1 error ClinicalUseDefinition Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot be used in the same instance (ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count() + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count() + ClinicalUseDefinition.warning.count()) < 2
dom-2 error ClinicalUseDefinition If the resource is contained in another resource, it SHALL NOT contain nested Resources contained.contained.empty()
dom-3 error ClinicalUseDefinition If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4 error ClinicalUseDefinition If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5 error ClinicalUseDefinition If a resource is contained in another resource, it SHALL NOT have a security label contained.meta.security.empty()
dom-6 best practice ClinicalUseDefinition A resource should have narrative for robust management text.`div`.exists()
ele-1 error **ALL** elements All FHIR elements must have a @value or children hasValue() or (children().count() > id.count())
ext-1 error **ALL** extensions Must have either extensions or value[x], not both extension.exists() != value.exists()

This structure is derived from ClinicalUseDefinition

Summary

Mandatory: 1 element
Fixed: 2 elements
Prohibited: 7 elements

Extensions

This structure refers to these extensions:

Key Elements View

NameFlagsCard.TypeDescription & Constraints    Filter: Filtersdoco
.. ClinicalUseDefinition C 0..* ClinicalUseDefinition A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure
Constraints: cud-1
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... contained 2..2 Medication Contained, inline Resources
... Slices for extension 0..* Extension Extension
Slice: Unordered, Open by value:url
.... extension:affected 0..* Reference(EETISMedicationStatement) MedicationStatements affected by interactions.
URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements
.... extension:link 0..* string Additional information from external source.
URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link
... type Σ 1..1 code indication | contraindication | interaction | undesirable-effect | warning
Binding: ClinicalUseDefinitionType (required): Overall defining type of this clinical use definition.
Fixed Value: interaction
... subject Σ 1..* Reference(Medication) medication A
.... reference ΣC 0..1 string Literal reference, Relative, internal or absolute URL
.... display ΣC 0..1 string Text alternative for the resource
Required Pattern: siia toimeaine nimetus

doco Documentation for this format

Terminology Bindings

Path Status Usage ValueSet Version Source
ClinicalUseDefinition.​type Base required Clinical Use Definition Type 📍5.0.0 FHIR Std.

Constraints

Id Grade Path(s) Description Expression
cud-1 error ClinicalUseDefinition Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot be used in the same instance (ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count() + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count() + ClinicalUseDefinition.warning.count()) < 2
dom-2 error ClinicalUseDefinition If the resource is contained in another resource, it SHALL NOT contain nested Resources contained.contained.empty()
dom-3 error ClinicalUseDefinition If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4 error ClinicalUseDefinition If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5 error ClinicalUseDefinition If a resource is contained in another resource, it SHALL NOT have a security label contained.meta.security.empty()
dom-6 best practice ClinicalUseDefinition A resource should have narrative for robust management text.`div`.exists()
ele-1 error **ALL** elements All FHIR elements must have a @value or children hasValue() or (children().count() > id.count())
ext-1 error **ALL** extensions Must have either extensions or value[x], not both extension.exists() != value.exists()

Differential View

This structure is derived from ClinicalUseDefinition

NameFlagsCard.TypeDescription & Constraints    Filter: Filtersdoco
.. ClinicalUseDefinition 0..* ClinicalUseDefinition A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure
... contained 2..2 Medication Contained, inline Resources
... Slices for extension 0..* Extension Extension
Slice: Unordered, Open by value:url
.... extension:affected 0..* Reference(EETISMedicationStatement) MedicationStatements affected by interactions.
URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements
.... extension:link 0..* string Additional information from external source.
URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link
... type 1..1 code indication | contraindication | interaction | undesirable-effect | warning
Fixed Value: interaction
.... display 0..1 string Text alternative for the resource
Required Pattern: siia toimeaine nimetus
... contraindication 0..0 Specifics for when this is a contraindication
... indication 0..0 Specifics for when this is an indication
... interaction
.... interactant
..... item[x] 1..1 Reference(Medication) medication B
.... type 0..1 CodeableConcept The type of the interaction e.g. drug-drug interaction, drug-lab test interaction
Fixed Value: As shown
..... coding 1..1 Coding Code defined by a terminology system
Fixed Value: (Complex)
...... system 1..1 uri Identity of the terminology system
Fixed Value: http://hl7.org/fhir/interaction-type
...... code 1..1 code Symbol in syntax defined by the system
Fixed Value: drug-drug
...... display 1..1 string Representation defined by the system
Fixed Value: drug to drug interaction
..... text 1..1 string Plain text representation of the concept
Fixed Value: drug to drug interaction
.... effect 0..1 CodeableReference(ObservationDefinition) Consequences (SYNBASE)
..... concept 0..1 CodeableConcept Consequences
...... text 0..1 string If not codeable, use text to represent consequenses
..... reference 0..0 Reference to a resource (by instance)
.... incidence 0..1 CodeableConcept Classification (SYNBASE. e.g. D0)
..... text 0..1 string Classification
.... management 0..1 CodeableConcept Recommendation (SYNBASE)
..... text 0..1 string If not codeable, use text to represent recommendation
... population 0..0 The population group to which this applies
... library 0..0 Logic used by the clinical use definition
... undesirableEffect 0..0 A possible negative outcome from the use of this treatment
... warning 0..0 Critical environmental, health or physical risks or hazards. For example 'Do not operate heavy machinery', 'May cause drowsiness'

doco Documentation for this format

Snapshot View

NameFlagsCard.TypeDescription & Constraints    Filter: Filtersdoco
.. ClinicalUseDefinition C 0..* ClinicalUseDefinition A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure
Constraints: cud-1
... id Σ 0..1 id Logical id of this artifact
... meta Σ 0..1 Meta Metadata about the resource
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... text 0..1 Narrative Text summary of the resource, for human interpretation
This profile does not constrain the narrative in regard to content, language, or traceability to data elements
... contained 2..2 Medication Contained, inline Resources
... Slices for extension 0..* Extension Extension
Slice: Unordered, Open by value:url
.... extension:affected 0..* Reference(EETISMedicationStatement) MedicationStatements affected by interactions.
URL: https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements
.... extension:link 0..* string Additional information from external source.
URL: https://fhir.ee/StructureDefinition/ee-tis-additional-information-link
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... identifier Σ 0..* Identifier Business identifier for this issue
... type Σ 1..1 code indication | contraindication | interaction | undesirable-effect | warning
Binding: ClinicalUseDefinitionType (required): Overall defining type of this clinical use definition.
Fixed Value: interaction
... category Σ 0..* CodeableConcept A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose"
Binding: ClinicalUseDefinitionCategory (preferred): A categorisation for a clinical use information item.
... subject Σ 1..* Reference(Medication) medication A
.... id 0..1 id Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
.... reference ΣC 0..1 string Literal reference, Relative, internal or absolute URL
.... type Σ 0..1 uri Type the reference refers to (e.g. "Patient") - must be a resource in resources
Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
.... identifier ΣC 0..1 Identifier Logical reference, when literal reference is not known
.... display ΣC 0..1 string Text alternative for the resource
Required Pattern: siia toimeaine nimetus
... status Σ 0..1 CodeableConcept Whether this is a current issue or one that has been retired etc
Binding: PublicationStatus (preferred): The lifecycle status of an artifact.
... interaction ΣC 0..1 BackboneElement Specifics for when this is an interaction
.... id 0..1 string Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
.... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... interactant Σ 0..* BackboneElement The specific medication, product, food etc. or laboratory test that interacts
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... item[x] Σ 1..1 Reference(Medication) medication B
.... type Σ 0..1 CodeableConcept The type of the interaction e.g. drug-drug interaction, drug-lab test interaction
Binding: InteractionType (example): A categorisation for an interaction between two substances.
Fixed Value: As shown
..... id 0..0 string Unique id for inter-element referencing
..... extension 0..0 Extension Additional content defined by implementations
..... coding 1..1 Coding Code defined by a terminology system
Fixed Value: (Complex)
...... id 0..0 string Unique id for inter-element referencing
...... extension 0..0 Extension Additional content defined by implementations
...... system 1..1 uri Identity of the terminology system
Fixed Value: http://hl7.org/fhir/interaction-type
...... version 0..0 string Version of the system - if relevant
...... code 1..1 code Symbol in syntax defined by the system
Fixed Value: drug-drug
...... display 1..1 string Representation defined by the system
Fixed Value: drug to drug interaction
...... userSelected 0..0 boolean If this coding was chosen directly by the user
..... text 1..1 string Plain text representation of the concept
Fixed Value: drug to drug interaction
.... effect Σ 0..1 CodeableReference(ObservationDefinition) Consequences (SYNBASE)
Binding: InteractionEffect (example): A interaction effect of clinical use of a medication or other substance.
..... id 0..1 id Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
..... concept Σ 0..1 CodeableConcept Consequences
...... id 0..1 id Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
...... coding Σ 0..* Coding Code defined by a terminology system
...... text Σ 0..1 string If not codeable, use text to represent consequenses
.... incidence Σ 0..1 CodeableConcept Classification (SYNBASE. e.g. D0)
Binding: InteractionIncidence (example): A categorisation for incidence of occurence of an interaction.
..... id 0..1 id Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
..... coding Σ 0..* Coding Code defined by a terminology system
..... text Σ 0..1 string Classification
.... management Σ 0..1 CodeableConcept Recommendation (SYNBASE)
Binding: InteractionManagement (example): A type of management for an interaction of a medication or other substance.
..... id 0..1 id Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
..... coding Σ 0..* Coding Code defined by a terminology system
..... text Σ 0..1 string If not codeable, use text to represent recommendation

doco Documentation for this format

Terminology Bindings

Path Status Usage ValueSet Version Source
ClinicalUseDefinition.​language Base required All Languages 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​type Base required Clinical Use Definition Type 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​category Base preferred Clinical Use Definition Category 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​subject.type Base extensible Resource Types 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​status Base preferred PublicationStatus 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​contraindication.diseaseSymptomProcedure Base example Disease Symptom Procedure 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​contraindication.diseaseStatus Base example Disease Status 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​contraindication.comorbidity Base example Disease Symptom Procedure 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​contraindication.otherTherapy.​relationshipType Base preferred Therapy Relationship Type 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​contraindication.otherTherapy.​treatment Base example Therapy 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​indication.diseaseSymptomProcedure Base example Disease Symptom Procedure 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​indication.diseaseStatus Base example Disease Status 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​indication.comorbidity Base example Disease Symptom Procedure 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​indication.intendedEffect Base preferred Product Intended Use 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​interaction.type Base example Interaction Type 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​interaction.effect Base example Interaction Effect 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​interaction.incidence Base example Interaction Incidence 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​interaction.management Base example Interaction Management 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​undesirableEffect.symptomConditionEffect Base example Undesirable Effect Symptom 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​undesirableEffect.classification Base example Undesirable Effect Classification 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​undesirableEffect.frequencyOfOccurrence Base example Undesirabl Effect Frequency 📍5.0.0 FHIR Std.
ClinicalUseDefinition.​warning.code Base example Warning Type 📍5.0.0 FHIR Std.

Constraints

Id Grade Path(s) Description Expression
cud-1 error ClinicalUseDefinition Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot be used in the same instance (ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count() + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count() + ClinicalUseDefinition.warning.count()) < 2
dom-2 error ClinicalUseDefinition If the resource is contained in another resource, it SHALL NOT contain nested Resources contained.contained.empty()
dom-3 error ClinicalUseDefinition If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4 error ClinicalUseDefinition If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5 error ClinicalUseDefinition If a resource is contained in another resource, it SHALL NOT have a security label contained.meta.security.empty()
dom-6 best practice ClinicalUseDefinition A resource should have narrative for robust management text.`div`.exists()
ele-1 error **ALL** elements All FHIR elements must have a @value or children hasValue() or (children().count() > id.count())
ext-1 error **ALL** extensions Must have either extensions or value[x], not both extension.exists() != value.exists()

This structure is derived from ClinicalUseDefinition

Summary

Mandatory: 1 element
Fixed: 2 elements
Prohibited: 7 elements

Extensions

This structure refers to these extensions:

 

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