medication-interaction1 - XML Representation - Medication Scheme Implementation Guide v1.0.0

Medication Scheme Implementation Guide, published by TEHIK. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/TEHIK-EE/ig-ee-medication-scheme/ and changes regularly. See the Directory of published versions
: medication-interaction1 - XML Representation

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<ClinicalUseDefinition xmlns="http://hl7.org/fhir">
  <id value="medication-interaction1"/>
  <meta>
    <profile
             value="https://fhir.ee/StructureDefinition/ee-tis-medication-interaction"/>
  </meta>
  <text>
    <status value="extensions"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: ClinicalUseDefinition medication-interaction1</b></p><a name="medication-interaction1"> </a><a name="hcmedication-interaction1"> </a><a name="medication-interaction1-en-US"> </a><p><b>ExtensionEETISAffectedMedicationStatements</b>: <a href="MedicationStatement-MedicationStatement-metformin.html">MedicationStatement: extension = ,100,2023-11-07,,,Avalik,order,; status = recorded; category = Pidev,ei ole patsiendi ytluse põhjal,tavaretsept,3-kordne; effective[x] = 2015-02-07 13:28:17-0500 --&gt; (ongoing); note = patsient peaks iga päev veresuhkrut mõõtma</a></p><p><b>ExtensionEETISAffectedMedicationStatements</b>: <a href="MedicationStatement-MedicationStatementAdrenalin.html">MedicationStatement: extension = ,5,2023-11-07,,,,,Privaatne,order,; status = recorded; category = Ühekordne,ei ole patsiendi ytluse põhjal,tavaretsept,1-kordne; effective[x] = 2015-02-07 13:28:17-0500 --&gt; (ongoing); note = lõpuks ometi sai müügiloataotlus rahuldatud ja saab ravimit tellida</a></p><p><b>ExtensionEETISAdditionalInformationLink</b>: www.synbase.ee/metformin+adrenalin</p><p><b>type</b>: Interaction</p><p><b>subject</b>: <a href="#hcmedication-interaction1/metformin">Medication: extension = metformiin; doseForm = tablett+õhukese polümeerikattega tablett; totalVolume = 120</a></p><p><b>status</b>: <span title="Codes:">active</span></p><blockquote><p><b>interaction</b></p><h3>Interactants</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Item[x]</b></td></tr><tr><td style="display: none">*</td><td><a href="#hcmedication-interaction1/adrenalin">Medication: extension = Epinefriin,1 ML,Adrenaliin; doseForm = süstelahus; totalVolume = 5</a></td></tr></table><p><b>type</b>: <span title="Codes:{http://hl7.org/fhir/interaction-type drug-drug}">drug to drug interaction</span></p><h3>Effects</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Concept</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:">Consequences. Ravim A vererõhku alandav ja diureetiline toime võib ravim B-ga kooskasutamisel nõrgeneda ning suurendada kehakaalu. Vererõhk kõrgeneb enamasti vähe või mõõdukalt, kuid hüpertensiooni tüsistuste tekke oht võib suureneda, eriti eakatel.</span></td></tr></table><p><b>incidence</b>: <span title="Codes:">D0</span></p><p><b>management</b>: <span title="Codes:">Recommendation. Kui kooskasutamine on vajalik, on soovitatav hoolikalt jälgida vererõhku ja kehakaalu. Ravimi A annust võib olla vaja kohandada. Kaaluda raviks xxx, kuna Ravim B ei vähenda toimet.</span></p></blockquote><hr/><blockquote><p class="res-header-id"><b>Generated Narrative: Medication  #metformin</b></p><a name="medication-interaction1/metformin"> </a><a name="hcmedication-interaction1/metformin"> </a><a name="medication-interaction1/metformin-en-US"> </a><p><b>ExtensionEETISMedicinalProductClassification</b>: <span title="Codes:{https://fhir.ee/CodeSystem/atc-ee A10BA02}">metformiin</span></p><p><b>doseForm</b>: <span title="Codes:{https://fhir.ee/CodeSystem/ravimvormid 1518}">tablett+õhukese polümeerikattega tablett</span></p><p><b>totalVolume</b>: 120</p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Concept</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{https://fhir.ee/CodeSystem/toimeained 11354}">metformiin</span></td></tr></table><p><b>isActive</b>: true</p><p><b>strength</b>: 500(unit MG from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style="background: LightGoldenRodYellow"> (Details: ER_Ühikud mahu- ja massiühikud  codeMG = 'milligram(s)')</span>/1(unit TABL from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style="background: LightGoldenRodYellow"> (Details: ER_Ühikud mahu- ja massiühikud  codeTABL = 'tablet(s)')</span></p></blockquote></blockquote><hr/><blockquote><p class="res-header-id"><b>Generated Narrative: Medication  #adrenalin</b></p><a name="medication-interaction1/adrenalin"> </a><a name="hcmedication-interaction1/adrenalin"> </a><a name="medication-interaction1/adrenalin-en-US"> </a><p><b>ExtensionEETISMedicinalProductClassification</b>: <span title="Codes:{https://fhir.ee/CodeSystem/atc-ee C01CA24}">Epinefriin</span></p><p><b>ExtensionEETISSizeOfItem</b>: 1(unit ML from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style="background: LightGoldenRodYellow"> (Details: ER_Ühikud mahu- ja massiühikud  codeML = 'milliliter(s)')</span></p><p><b>ExtensionEETISMedicinalProductName</b>: Adrenaliin</p><p><b>doseForm</b>: <span title="Codes:{https://fhir.ee/CodeSystem/ravimvormid 739}">süstelahus</span></p><p><b>totalVolume</b>: 5</p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Concept</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{https://fhir.ee/CodeSystem/toimeained 8554}">epinefriin</span></td></tr></table><p><b>isActive</b>: true</p><p><b>strength</b>: 1(unit MG from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style="background: LightGoldenRodYellow"> (Details: ER_Ühikud mahu- ja massiühikud  codeMG = 'milligram(s)')</span>/1(unit ML from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style="background: LightGoldenRodYellow"> (Details: ER_Ühikud mahu- ja massiühikud  codeML = 'milliliter(s)')</span></p></blockquote></blockquote></div>
  </text>
  <contained>
    <Medication>
      <id value="metformin"/>
      <meta>
        <profile
                 value="https://fhir.ee/StructureDefinition/ee-tis-medication-epc"/>
      </meta>
      <extension
                 url="https://fhir.ee/StructureDefinition/ee-tis-medicinal-product-classification">
        <valueCodeableConcept>
          <coding>
            <system value="https://fhir.ee/CodeSystem/atc-ee"/>
            <code value="A10BA02"/>
            <display value="metformiin"/>
          </coding>
        </valueCodeableConcept>
      </extension>
      <doseForm>
        <coding>
          <system value="https://fhir.ee/CodeSystem/ravimvormid"/>
          <code value="1518"/>
          <display value="tablett+õhukese polümeerikattega tablett"/>
        </coding>
      </doseForm>
      <totalVolume>
        <value value="120"/>
      </totalVolume>
      <ingredient>
        <item>
          <concept>
            <coding>
              <system value="https://fhir.ee/CodeSystem/toimeained"/>
              <code value="11354"/>
              <display value="metformiin"/>
            </coding>
          </concept>
        </item>
        <isActive value="true"/>
        <strengthRatio>
          <numerator>
            <value value="500"/>
            <system
                    value="https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik"/>
            <code value="MG"/>
          </numerator>
          <denominator>
            <value value="1"/>
            <system
                    value="https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik"/>
            <code value="TABL"/>
          </denominator>
        </strengthRatio>
      </ingredient>
    </Medication>
  </contained>
  <contained>
    <Medication>
      <id value="adrenalin"/>
      <meta>
        <profile
                 value="https://fhir.ee/StructureDefinition/ee-tis-medication-epc"/>
      </meta>
      <extension
                 url="https://fhir.ee/StructureDefinition/ee-tis-medicinal-product-classification">
        <valueCodeableConcept>
          <coding>
            <system value="https://fhir.ee/CodeSystem/atc-ee"/>
            <code value="C01CA24"/>
            <display value="Epinefriin"/>
          </coding>
        </valueCodeableConcept>
      </extension>
      <extension
                 url="https://fhir.ee/StructureDefinition/ee-tis-size-of-item">
        <valueQuantity>
          <value value="1"/>
          <system
                  value="https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik"/>
          <code value="ML"/>
        </valueQuantity>
      </extension>
      <extension
                 url="https://fhir.ee/StructureDefinition/ee-tis-medicinal-product-name">
        <valueString value="Adrenaliin"/>
      </extension>
      <doseForm>
        <coding>
          <system value="https://fhir.ee/CodeSystem/ravimvormid"/>
          <code value="739"/>
          <display value="süstelahus"/>
        </coding>
      </doseForm>
      <totalVolume>
        <value value="5"/>
      </totalVolume>
      <ingredient>
        <item>
          <concept>
            <coding>
              <system value="https://fhir.ee/CodeSystem/toimeained"/>
              <code value="8554"/>
              <display value="epinefriin"/>
            </coding>
          </concept>
        </item>
        <isActive value="true"/>
        <strengthRatio>
          <numerator>
            <value value="1"/>
            <system
                    value="https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik"/>
            <code value="MG"/>
          </numerator>
          <denominator>
            <value value="1"/>
            <system
                    value="https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik"/>
            <code value="ML"/>
          </denominator>
        </strengthRatio>
      </ingredient>
    </Medication>
  </contained>
  <extension
             url="https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements">
    <valueReference>🔗 
      <reference value="MedicationStatement/MedicationStatement-metformin"/>
    </valueReference>
  </extension>
  <extension
             url="https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements">
    <valueReference>🔗 
      <reference value="MedicationStatement/MedicationStatementAdrenalin"/>
    </valueReference>
  </extension>
  <extension
             url="https://fhir.ee/StructureDefinition/ee-tis-additional-information-link">
    <valueString value="www.synbase.ee/metformin+adrenalin"/>
  </extension>
  <type value="interaction"/>
  <subject>
    <reference value="#metformin"/>
  </subject>
  <status>
    <coding>
      <code value="active"/>
    </coding>
  </status>
  <interaction>
    <interactant>
      <itemReference>
        <reference value="#adrenalin"/>
      </itemReference>
    </interactant>
    <type>
      <coding>
        <system value="http://hl7.org/fhir/interaction-type"/>
        <code value="drug-drug"/>
        <display value="drug to drug interaction"/>
      </coding>
      <text value="drug to drug interaction"/>
    </type>
    <effect>
      <concept>
        <text
              value="Consequences. Ravim A vererõhku alandav ja diureetiline toime võib ravim B-ga kooskasutamisel nõrgeneda ning suurendada kehakaalu. Vererõhk kõrgeneb enamasti vähe või mõõdukalt, kuid hüpertensiooni tüsistuste tekke oht võib suureneda, eriti eakatel."/>
      </concept>
    </effect>
    <incidence>
      <text value="D0"/>
    </incidence>
    <management>
      <text
            value="Recommendation. Kui kooskasutamine on vajalik, on soovitatav hoolikalt jälgida vererõhku ja kehakaalu. Ravimi A annust võib olla vaja kohandada. Kaaluda raviks xxx, kuna Ravim B ei vähenda toimet."/>
    </management>
  </interaction>
</ClinicalUseDefinition>