Medication Scheme Implementation Guide
1.0.0 - draft Estonia flag

Medication Scheme Implementation Guide, published by TEHIK. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/TEHIK-EE/ig-ee-medication-scheme/ and changes regularly. See the Directory of published versions

: medication-interaction1 - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:ClinicalUseDefinition ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "medication-interaction1"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://fhir.ee/StructureDefinition/ee-tis-medication-interaction"^^xsd:anyURI ;
fhir:link <https://fhir.ee/StructureDefinition/ee-tis-medication-interaction>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ClinicalUseDefinition medication-interaction1</b></p><a name=\"medication-interaction1\"> </a><a name=\"hcmedication-interaction1\"> </a><a name=\"medication-interaction1-en-US\"> </a><p><b>ExtensionEETISAffectedMedicationStatements</b>: <a href=\"MedicationStatement-MedicationStatement-metformin.html\">MedicationStatement: extension = ,100,2023-11-07,,,Avalik,order,; status = recorded; category = Pidev,ei ole patsiendi ytluse põhjal,tavaretsept,3-kordne; effective[x] = 2015-02-07 13:28:17-0500 --&gt; (ongoing); note = patsient peaks iga päev veresuhkrut mõõtma</a></p><p><b>ExtensionEETISAffectedMedicationStatements</b>: <a href=\"MedicationStatement-MedicationStatementAdrenalin.html\">MedicationStatement: extension = ,5,2023-11-07,,,,,Privaatne,order,; status = recorded; category = Ühekordne,ei ole patsiendi ytluse põhjal,tavaretsept,1-kordne; effective[x] = 2015-02-07 13:28:17-0500 --&gt; (ongoing); note = lõpuks ometi sai müügiloataotlus rahuldatud ja saab ravimit tellida</a></p><p><b>ExtensionEETISAdditionalInformationLink</b>: www.synbase.ee/metformin+adrenalin</p><p><b>type</b>: Interaction</p><p><b>subject</b>: <a href=\"#hcmedication-interaction1/metformin\">Medication: extension = metformiin; doseForm = tablett+õhukese polümeerikattega tablett; totalVolume = 120</a></p><p><b>status</b>: <span title=\"Codes:\">active</span></p><blockquote><p><b>interaction</b></p><h3>Interactants</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Item[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"#hcmedication-interaction1/adrenalin\">Medication: extension = Epinefriin,1 ML,Adrenaliin; doseForm = süstelahus; totalVolume = 5</a></td></tr></table><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/interaction-type drug-drug}\">drug to drug interaction</span></p><h3>Effects</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">Consequences. Ravim A vererõhku alandav ja diureetiline toime võib ravim B-ga kooskasutamisel nõrgeneda ning suurendada kehakaalu. Vererõhk kõrgeneb enamasti vähe või mõõdukalt, kuid hüpertensiooni tüsistuste tekke oht võib suureneda, eriti eakatel.</span></td></tr></table><p><b>incidence</b>: <span title=\"Codes:\">D0</span></p><p><b>management</b>: <span title=\"Codes:\">Recommendation. Kui kooskasutamine on vajalik, on soovitatav hoolikalt jälgida vererõhku ja kehakaalu. Ravimi A annust võib olla vaja kohandada. Kaaluda raviks xxx, kuna Ravim B ei vähenda toimet.</span></p></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Medication  #metformin</b></p><a name=\"medication-interaction1/metformin\"> </a><a name=\"hcmedication-interaction1/metformin\"> </a><a name=\"medication-interaction1/metformin-en-US\"> </a><p><b>ExtensionEETISMedicinalProductClassification</b>: <span title=\"Codes:{https://fhir.ee/CodeSystem/atc-ee A10BA02}\">metformiin</span></p><p><b>doseForm</b>: <span title=\"Codes:{https://fhir.ee/CodeSystem/ravimvormid 1518}\">tablett+õhukese polümeerikattega tablett</span></p><p><b>totalVolume</b>: 120</p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{https://fhir.ee/CodeSystem/toimeained 11354}\">metformiin</span></td></tr></table><p><b>isActive</b>: true</p><p><b>strength</b>: 500(unit MG from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: ER_Ühikud mahu- ja massiühikud  codeMG = 'milligram(s)')</span>/1(unit TABL from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: ER_Ühikud mahu- ja massiühikud  codeTABL = 'tablet(s)')</span></p></blockquote></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Medication  #adrenalin</b></p><a name=\"medication-interaction1/adrenalin\"> </a><a name=\"hcmedication-interaction1/adrenalin\"> </a><a name=\"medication-interaction1/adrenalin-en-US\"> </a><p><b>ExtensionEETISMedicinalProductClassification</b>: <span title=\"Codes:{https://fhir.ee/CodeSystem/atc-ee C01CA24}\">Epinefriin</span></p><p><b>ExtensionEETISSizeOfItem</b>: 1(unit ML from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: ER_Ühikud mahu- ja massiühikud  codeML = 'milliliter(s)')</span></p><p><b>ExtensionEETISMedicinalProductName</b>: Adrenaliin</p><p><b>doseForm</b>: <span title=\"Codes:{https://fhir.ee/CodeSystem/ravimvormid 739}\">süstelahus</span></p><p><b>totalVolume</b>: 5</p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{https://fhir.ee/CodeSystem/toimeained 8554}\">epinefriin</span></td></tr></table><p><b>isActive</b>: true</p><p><b>strength</b>: 1(unit MG from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: ER_Ühikud mahu- ja massiühikud  codeMG = 'milligram(s)')</span>/1(unit ML from https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik)<span style=\"background: LightGoldenRodYellow\"> (Details: ER_Ühikud mahu- ja massiühikud  codeML = 'milliliter(s)')</span></p></blockquote></blockquote></div>"
  ] ; # 
  fhir:contained ( [
a fhir:Medication ;
fhir:id [ fhir:v "metformin" ] ;
fhir:meta [
      ( fhir:profile [
fhir:v "https://fhir.ee/StructureDefinition/ee-tis-medication-epc"^^xsd:anyURI ;
fhir:link <https://fhir.ee/StructureDefinition/ee-tis-medication-epc>       ] )     ] ;
    ( fhir:extension [
fhir:url [ fhir:v "https://fhir.ee/StructureDefinition/ee-tis-medicinal-product-classification"^^xsd:anyURI ] ;
fhir:value [
a fhir:CodeableConcept ;
        ( fhir:coding [
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/atc-ee"^^xsd:anyURI ] ;
fhir:code [ fhir:v "A10BA02" ] ;
fhir:display [ fhir:v "metformiin" ]         ] )       ]     ] ) ;
fhir:doseForm [
      ( fhir:coding [
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/ravimvormid"^^xsd:anyURI ] ;
fhir:code [ fhir:v "1518" ] ;
fhir:display [ fhir:v "tablett+õhukese polümeerikattega tablett" ]       ] )     ] ;
fhir:totalVolume [
fhir:value [ fhir:v "120"^^xsd:decimal ]     ] ;
    ( fhir:ingredient [
fhir:item [
fhir:concept [
          ( fhir:coding [
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/toimeained"^^xsd:anyURI ] ;
fhir:code [ fhir:v "11354" ] ;
fhir:display [ fhir:v "metformiin" ]           ] )         ]       ] ;
fhir:isActive [ fhir:v "true"^^xsd:boolean ] ;
fhir:strength [
a fhir:Ratio ;
fhir:numerator [
fhir:value [ fhir:v "500"^^xsd:decimal ] ;
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik"^^xsd:anyURI ] ;
fhir:code [ fhir:v "MG" ]         ] ;
fhir:denominator [
fhir:value [ fhir:v "1"^^xsd:decimal ] ;
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik"^^xsd:anyURI ] ;
fhir:code [ fhir:v "TABL" ]         ]       ]     ] )
  ] [
a fhir:Medication ;
fhir:id [ fhir:v "adrenalin" ] ;
fhir:meta [
      ( fhir:profile [
fhir:v "https://fhir.ee/StructureDefinition/ee-tis-medication-epc"^^xsd:anyURI ;
fhir:link <https://fhir.ee/StructureDefinition/ee-tis-medication-epc>       ] )     ] ;
    ( fhir:extension [
fhir:url [ fhir:v "https://fhir.ee/StructureDefinition/ee-tis-medicinal-product-classification"^^xsd:anyURI ] ;
fhir:value [
a fhir:CodeableConcept ;
        ( fhir:coding [
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/atc-ee"^^xsd:anyURI ] ;
fhir:code [ fhir:v "C01CA24" ] ;
fhir:display [ fhir:v "Epinefriin" ]         ] )       ]     ] [
fhir:url [ fhir:v "https://fhir.ee/StructureDefinition/ee-tis-size-of-item"^^xsd:anyURI ] ;
fhir:value [
a fhir:Quantity ;
fhir:value [ fhir:v "1"^^xsd:decimal ] ;
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ML" ]       ]     ] [
fhir:url [ fhir:v "https://fhir.ee/StructureDefinition/ee-tis-medicinal-product-name"^^xsd:anyURI ] ;
fhir:value [ fhir:v "Adrenaliin" ]     ] ) ;
fhir:doseForm [
      ( fhir:coding [
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/ravimvormid"^^xsd:anyURI ] ;
fhir:code [ fhir:v "739" ] ;
fhir:display [ fhir:v "süstelahus" ]       ] )     ] ;
fhir:totalVolume [
fhir:value [ fhir:v "5"^^xsd:decimal ]     ] ;
    ( fhir:ingredient [
fhir:item [
fhir:concept [
          ( fhir:coding [
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/toimeained"^^xsd:anyURI ] ;
fhir:code [ fhir:v "8554" ] ;
fhir:display [ fhir:v "epinefriin" ]           ] )         ]       ] ;
fhir:isActive [ fhir:v "true"^^xsd:boolean ] ;
fhir:strength [
a fhir:Ratio ;
fhir:numerator [
fhir:value [ fhir:v "1"^^xsd:decimal ] ;
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik"^^xsd:anyURI ] ;
fhir:code [ fhir:v "MG" ]         ] ;
fhir:denominator [
fhir:value [ fhir:v "1"^^xsd:decimal ] ;
fhir:system [ fhir:v "https://fhir.ee/CodeSystem/retsept-mahu-ja-massiyhik"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ML" ]         ]       ]     ] )
  ] ) ; # 
  fhir:extension ( [
fhir:url [ fhir:v "https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements"^^xsd:anyURI ] ;
fhir:value [
a fhir:Reference ;
fhir:reference [ fhir:v "MedicationStatement/MedicationStatement-metformin" ]     ]
  ] [
fhir:url [ fhir:v "https://fhir.ee/StructureDefinition/ee-tis-affected-medication-statements"^^xsd:anyURI ] ;
fhir:value [
a fhir:Reference ;
fhir:reference [ fhir:v "MedicationStatement/MedicationStatementAdrenalin" ]     ]
  ] [
fhir:url [ fhir:v "https://fhir.ee/StructureDefinition/ee-tis-additional-information-link"^^xsd:anyURI ] ;
fhir:value [ fhir:v "www.synbase.ee/metformin+adrenalin" ]
  ] ) ; # 
  fhir:type [ fhir:v "interaction"] ; # 
  fhir:subject ( [
fhir:reference [ fhir:v "#metformin" ]
  ] ) ; # 
  fhir:status [
    ( fhir:coding [
fhir:code [ fhir:v "active" ]     ] )
  ] ; # 
  fhir:interaction [
    ( fhir:interactant [
fhir:item [
a fhir:Reference ;
fhir:reference [ fhir:v "#adrenalin" ]       ]     ] ) ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/interaction-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "drug-drug" ] ;
fhir:display [ fhir:v "drug to drug interaction" ]       ] ) ;
fhir:text [ fhir:v "drug to drug interaction" ]     ] ;
fhir:effect [
fhir:concept [
fhir:text [ fhir:v "Consequences. Ravim A vererõhku alandav ja diureetiline toime võib ravim B-ga kooskasutamisel nõrgeneda ning suurendada kehakaalu. Vererõhk kõrgeneb enamasti vähe või mõõdukalt, kuid hüpertensiooni tüsistuste tekke oht võib suureneda, eriti eakatel." ]       ]     ] ;
fhir:incidence [
fhir:text [ fhir:v "D0" ]     ] ;
    ( fhir:management [
fhir:text [ fhir:v "Recommendation. Kui kooskasutamine on vajalik, on soovitatav hoolikalt jälgida vererõhku ja kehakaalu. Ravimi A annust võib olla vaja kohandada. Kaaluda raviks xxx, kuna Ravim B ei vähenda toimet." ]     ] )
  ] . #