Pharmaceutical Quality (Industry)
1.0.0 - STU1 International flag

Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions

: Example: Bundle - Process Validation, product - JSON Representation

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//  Product Process Validation 
{
  "resourceType" : "Bundle",
  "id" : "bundle-product-process-validation-pq-ex1",
  "meta" : {
    "profile" : [
      🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-product-process-validation-pq"
    ]
  },
  "type" : "collection",
  "entry" : [
    {
      "fullUrl" : "urn:uuid:2038e4c7-22b8-4c56-2d28-6c077648763f",
      "resource" : {
        "resourceType" : "PlanDefinition",
        "id" : "2038e4c7-22b8-4c56-2d28-6c077648763f",
        "text" : // validationProtocol
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_2038e4c7-22b8-4c56-2d28-6c077648763f\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"2038e4c7-22b8-4c56-2d28-6c077648763f\"> </a><a name=\"hc2038e4c7-22b8-4c56-2d28-6c077648763f\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition &quot;2038e4c7-22b8-4c56-2d28-6c077648763f&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</code></p><p><b>title</b>: DP PROCESS VALIDATION</p><p><b>type</b>: Workflow Definition <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-plan-definition-type.html\">PlanDefinitionType</a>#workflow-definition; <a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#process-validation &quot;Process Validation&quot;)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>description</b>: Pre-defined validation acceptance criteria were established based on manufacturing development data derived from process characterization studies...</p><blockquote><p><b>action</b></p><p><b>title</b>: Compounding Step</p><p><b>code</b>: Compounding Step <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#compounding)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: Compounding Steps</p><p><b>code</b>: Compounding <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Filling Steps</p><p><b>code</b>: Filling Step <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#filling)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: ???</p><p><b>code</b>: ??? <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Lyophilization Step</p><p><b>code</b>: Lyophilization Step <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#lyophilization)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424\">http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424\">http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e\">http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467\">http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467</a></td></tr><tr><td style=\"display: none\">*</td><td>Homogeneity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467\">http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467</a></td></tr><tr><td style=\"display: none\">*</td><td>Homogeneity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467\">http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Release Step</p><p><b>code</b>: Release Step <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#release)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: ???</p><p><b>code</b>: ??? <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote></div>"
        },
        "url" : "http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f",
        "title" : "DP PROCESS VALIDATION",
        "type" : // http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f
        {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/plan-definition-type",
              "code" : "workflow-definition",
              "display" : "Workflow Definition"
            },
            {
              "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
              "code" : "process-validation",
              "display" : "Process Validation"
            }
          ]
        },
        "status" : "active",
        "subjectReference" : {
          "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
        },
        "description" : "Pre-defined validation acceptance criteria were established based on manufacturing development data derived from process characterization studies...",
        "action" : [
          // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
          {
            "title" : "Compounding Step",
            "code" : // text value="Overall set of actions"/
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                  "code" : "compounding",
                  "display" : "Compounding Step"
                }
              ]
            },
            "action" : [
              {
                "title" : "Compounding Steps",
                "code" : //  this level is not really needed here, could remove. But in the case where there are different timings, it is needed, so it is here for consistency 
                {
                  "text" : "Compounding"
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"
                  },
                  // ObservationDefinition/compoundingpHPre
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"
                  },
                  // ObservationDefinition/compoundingpHPost
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"
                  },
                  // ObservationDefinition/compoundingAssayPre
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"
                  }
                ]
              }
            ]
          },
          // ObservationDefinition/compoundingAssayPost
          {
            "title" : "Filling Steps",
            "code" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                  "code" : "filling",
                  "display" : "Filling Step"
                }
              ]
            },
            "action" : [
              {
                "title" : "???",
                "code" : {
                  "text" : "???"
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Conclusion"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424"
                  },
                  // ObservationDefinition/conclusion
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424"
                  },
                  // ObservationDefinition/TAMC
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424"
                  },
                  // ObservationDefinition/TYMC
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-938ce1958424"
                  },
                  // ObservationDefinition/FillWeightAverage
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64525a3c-5134-448a-9c19-938ce1958424"
                  },
                  // ObservationDefinition/FillWeightTarget
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c29-938ce1958424"
                  },
                  // ObservationDefinition/FillWeightAverageFromTarget
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5234-448a-9c29-938ce1958424"
                  },
                  // ObservationDefinition/HoldTimeFiltrationToFilling
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5334-448a-9c29-938ce1958424"
                  },
                  // ObservationDefinition/HoldTimeFilling
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce1958424"
                  }
                ]
              }
            ]
          },
          // ObservationDefinition/FilterIntegrity
          {
            "title" : "Lyophilization Step",
            "code" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                  "code" : "lyophilization",
                  "display" : "Lyophilization Step"
                }
              ]
            },
            "action" : [
              {
                "code" : {
                  "text" : "Conclusion"
                },
                "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424"
              },
              // ObservationDefinition/LyophilizationConclusion
              {
                "code" : {
                  "text" : "Test"
                },
                "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424"
              },
              // ObservationDefinition/LyophilizerNumber
              {
                "code" : {
                  "text" : "Test"
                },
                "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e"
              },
              // ObservationDefinition/LyophilizationAssay
              {
                "code" : {
                  "text" : "Test"
                },
                "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467"
              },
              // ObservationDefinition/LyophilizationWater
              {
                "code" : {
                  "text" : "Homogeneity"
                },
                "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467"
              },
              // ObservationDefinition/LyophilizationWaterHomogeneity
              {
                "code" : {
                  "text" : "Homogeneity"
                },
                "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467"
              }
            ]
          },
          // ObservationDefinition/LyophilizationAssayHomogeneity
          {
            "title" : "Release Step",
            "code" : // text value="Overall set of actions"/
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                  "code" : "release",
                  "display" : "Release Step"
                }
              ]
            },
            "action" : [
              {
                "title" : "???",
                "code" : {
                  "text" : "???"
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c2-2d06-47cb5b295e72"
                  },
                  // ObservationDefinition/AppearanceProduct
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d16-47cb5b295e72"
                  },
                  // ObservationDefinition/AppearanceLyophilized
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d06-47cb5b295e72"
                  },
                  // ObservationDefinition/AppearanceReconstituted
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"
                  },
                  // ObservationDefinition/Identification
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e"
                  },
                  // ObservationDefinition/Assay
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
                  },
                  // ObservationDefinition/Degradation
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"
                  },
                  // ObservationDefinition/Water
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d7"
                  },
                  // ObservationDefinition/UniformityUSP
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d8"
                  },
                  // ObservationDefinition/UniformityAcceptance
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d06-47cb5b295e72"
                  }
                ]
              }
            ]
          }
        ]
      }
    },
    // ObservationDefinition/releasepH
    {
      "fullUrl" : "urn:uuid:fc17b5d5-9fe1-91c2-2d06-47cb5b295e72",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "fc17b5d5-9fe1-91c2-2d06-47cb5b295e72",
        "text" : // compoundingpHPre
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc17b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc17b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a><a name=\"hcfc17b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc17b5d5-9fe1-91c2-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: pH (adjustment of pre-clarification bulk solution)</p><p><b>status</b>: active</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>6.9-7.1 pH</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72",
        "title" : "pH (adjustment of pre-clarification bulk solution)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "pH (adjustment of pre-clarification bulk solution)",
              "display" : "pH (adjustment of pre-clarification bulk solution)"
            }
          ],
          "text" : "pH (adjustment of pre-clarification bulk solution)"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "low" : {
                "value" : 6.9,
                "unit" : "pH",
                "system" : "http://unitsofmeasure.org",
                "code" : "pH"
              },
              "high" : {
                "value" : 7.1,
                "unit" : "pH",
                "system" : "http://unitsofmeasure.org",
                "code" : "pH"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:fc17b5d5-9fe1-91c2-2d06-47cb5b295e73",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "fc17b5d5-9fe1-91c2-2d06-47cb5b295e73",
        "text" : // compoundingpHPost
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc17b5d5-9fe1-91c2-2d06-47cb5b295e73\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc17b5d5-9fe1-91c2-2d06-47cb5b295e73\"> </a><a name=\"hcfc17b5d5-9fe1-91c2-2d06-47cb5b295e73\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc17b5d5-9fe1-91c2-2d06-47cb5b295e73&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</code></p><p><b>title</b>: pH (post-dilution bulk solution)</p><p><b>status</b>: active</p><p><b>code</b>: pH (post-dilution bulk solution) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH (post-dilution bulk solution))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>7.0-7.1 pH</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73",
        "title" : "pH (post-dilution bulk solution)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "pH (post-dilution bulk solution)",
              "display" : "pH (post-dilution bulk solution)"
            }
          ],
          "text" : "pH (post-dilution bulk solution)"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "low" : {
                "value" : 7.0,
                "unit" : "pH",
                "system" : "http://unitsofmeasure.org",
                "code" : "pH"
              },
              "high" : {
                "value" : 7.1,
                "unit" : "pH",
                "system" : "http://unitsofmeasure.org",
                "code" : "pH"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:fd17b5d5-9fe1-91c2-2d06-47cb5b295e72",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "fd17b5d5-9fe1-91c2-2d06-47cb5b295e72",
        "text" : // compoundingAssayPre
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fd17b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fd17b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a><a name=\"hcfd17b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fd17b5d5-9fe1-91c2-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: Assay (pre-clarification filtration) (mg/mL)</p><p><b>status</b>: active</p><p><b>code</b>: Assay (pre-clarification filtration) (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Assay (pre-clarification filtration) (mg/mL))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>22-? mg/mL</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72",
        "title" : "Assay (pre-clarification filtration) (mg/mL)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Assay (pre-clarification filtration) (mg/mL)",
              "display" : "Assay (pre-clarification filtration) (mg/mL)"
            }
          ],
          "text" : "Assay (pre-clarification filtration) (mg/mL)"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "low" : //  todo correct this and the others 
              {
                "value" : 22,
                "unit" : "mg/mL",
                "system" : "http://unitsofmeasure.org",
                "code" : "mg/mL"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:fd17b5d5-9fe1-91c2-2d06-47cb5b295e73",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "fd17b5d5-9fe1-91c2-2d06-47cb5b295e73",
        "text" : // compoundingAssayPost
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fd17b5d5-9fe1-91c2-2d06-47cb5b295e73\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fd17b5d5-9fe1-91c2-2d06-47cb5b295e73\"> </a><a name=\"hcfd17b5d5-9fe1-91c2-2d06-47cb5b295e73\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fd17b5d5-9fe1-91c2-2d06-47cb5b295e73&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73</code></p><p><b>title</b>: Assay (Post dilution bulk solution) (mg/mL)</p><p><b>status</b>: active</p><p><b>code</b>: Assay (Post dilution bulk solution) (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Assay (Post dilution bulk solution) (mg/mL))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>20-21 mg/mL</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73",
        "title" : "Assay (Post dilution bulk solution) (mg/mL)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Assay (Post dilution bulk solution) (mg/mL)",
              "display" : "Assay (Post dilution bulk solution) (mg/mL)"
            }
          ],
          "text" : "Assay (Post dilution bulk solution) (mg/mL)"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "low" : //  todo correct this 
              {
                "value" : 20,
                "unit" : "mg/mL",
                "system" : "http://unitsofmeasure.org",
                "code" : "mg/mL"
              },
              "high" : //  todo correct this 
              {
                "value" : 21,
                "unit" : "mg/mL",
                "system" : "http://unitsofmeasure.org",
                "code" : "mg/mL"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:fc07b5d5-9fe1-92c2-2d06-47cb5b295e72",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "fc07b5d5-9fe1-92c2-2d06-47cb5b295e72",
        "text" : // AppearanceProduct
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc07b5d5-9fe1-92c2-2d06-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc07b5d5-9fe1-92c2-2d06-47cb5b295e72\"> </a><a name=\"hcfc07b5d5-9fe1-92c2-2d06-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc07b5d5-9fe1-92c2-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c2-2d06-47cb5b295e72</code></p><p><b>title</b>: Appearance (Product Container, visual)</p><p><b>status</b>: active</p><p><b>code</b>: Appearance (Product Container, visual) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Appearance (Product Container, visual))</span></p><p><b>method</b>: Visual inspection <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c2-2d06-47cb5b295e72",
        "title" : "Appearance (Product Container, visual)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c2-2d06-47cb5b295e72
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Appearance (Product Container, visual)",
              "display" : "Appearance (Product Container, visual)"
            }
          ],
          "text" : "Appearance (Product Container, visual)"
        },
        "method" : {
          "text" : "Visual inspection"
        },
        "qualifiedValue" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                "valueString" : "1)  Clear glass vial sealed with a gray rubber stopper and a flip off overseal 2)  No visible damage or breach of vial container or closure"
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:fc07b5d5-9fe1-92c3-2d16-47cb5b295e72",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "fc07b5d5-9fe1-92c3-2d16-47cb5b295e72",
        "text" : // AppearanceLyophilized
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc07b5d5-9fe1-92c3-2d16-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc07b5d5-9fe1-92c3-2d16-47cb5b295e72\"> </a><a name=\"hcfc07b5d5-9fe1-92c3-2d16-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc07b5d5-9fe1-92c3-2d16-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d16-47cb5b295e72</code></p><p><b>title</b>: Appearance (Lyophilized, Visual)</p><p><b>status</b>: active</p><p><b>code</b>: Appearance (Lyophilized, Visual) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Appearance (Lyophilized, Visual))</span></p><p><b>method</b>: Visual inspection <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d16-47cb5b295e72",
        "title" : "Appearance (Lyophilized, Visual)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d16-47cb5b295e72
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Appearance (Lyophilized, Visual)",
              "display" : "Appearance (Lyophilized, Visual)"
            }
          ],
          "text" : "Appearance (Lyophilized, Visual)"
        },
        "method" : {
          "text" : "Visual inspection"
        },
        "qualifiedValue" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                "valueString" : "White to off white cake or powder, essentially free from evidence of contamination with no visible foreign particulates"
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:fc07b5d5-9fe1-92c3-2d06-47cb5b295e72",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "fc07b5d5-9fe1-92c3-2d06-47cb5b295e72",
        "text" : // AppearanceReconstituted
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc07b5d5-9fe1-92c3-2d06-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc07b5d5-9fe1-92c3-2d06-47cb5b295e72\"> </a><a name=\"hcfc07b5d5-9fe1-92c3-2d06-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc07b5d5-9fe1-92c3-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d06-47cb5b295e72</code></p><p><b>title</b>: Appearance (Reconstituted, Visual)</p><p><b>status</b>: active</p><p><b>code</b>: Appearance (Reconstituted, Visual) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Appearance (Reconstituted, Visual))</span></p><p><b>method</b>: Visual inspection <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d06-47cb5b295e72",
        "title" : "Appearance (Reconstituted, Visual)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d06-47cb5b295e72
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Appearance (Reconstituted, Visual)",
              "display" : "Appearance (Reconstituted, Visual)"
            }
          ],
          "text" : "Appearance (Reconstituted, Visual)"
        },
        "method" : {
          "text" : "Visual inspection"
        },
        "qualifiedValue" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                "valueString" : "Clear, colorless to slightly yellow solution, essentially free of visible particulates"
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:3b0e878e-4bc9-8864-862f-e28b21233e8d",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "3b0e878e-4bc9-8864-862f-e28b21233e8d",
        "text" : // Identification
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_3b0e878e-4bc9-8864-862f-e28b21233e8d\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"3b0e878e-4bc9-8864-862f-e28b21233e8d\"> </a><a name=\"hc3b0e878e-4bc9-8864-862f-e28b21233e8d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;3b0e878e-4bc9-8864-862f-e28b21233e8d&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</code></p><p><b>title</b>: Identification</p><p><b>status</b>: active</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>method</b>: ID by UHPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d",
        "title" : "Identification",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "IDT",
              "display" : "Identification"
            }
          ],
          "text" : "Identification"
        },
        "method" : {
          "text" : "ID by UHPLC"
        },
        "qualifiedValue" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                "valueString" : "Consistent with the retention time and UV spectrum of the reference standard"
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:12e7e672-40a6-4036-3c1f-b8ba6a7d045e",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "12e7e672-40a6-4036-3c1f-b8ba6a7d045e",
        "text" : // Assay
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_12e7e672-40a6-4036-3c1f-b8ba6a7d045e\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"12e7e672-40a6-4036-3c1f-b8ba6a7d045e\"> </a><a name=\"hc12e7e672-40a6-4036-3c1f-b8ba6a7d045e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;12e7e672-40a6-4036-3c1f-b8ba6a7d045e&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e</code></p><p><b>title</b>: Assay</p><p><b>status</b>: active</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>method</b>: Assay by UHPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e",
        "title" : "Assay",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "ASSAY",
              "display" : "Assay"
            }
          ],
          "text" : "Assay"
        },
        "method" : {
          "text" : "Assay by UHPLC"
        },
        "qualifiedValue" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                "valueString" : "95% to 105% of label claim"
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:8bdea820-4197-7c7d-0990-7be06bf78aaf",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "8bdea820-4197-7c7d-0990-7be06bf78aaf",
        "text" : // Degradation
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_8bdea820-4197-7c7d-0990-7be06bf78aaf\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"8bdea820-4197-7c7d-0990-7be06bf78aaf\"> </a><a name=\"hc8bdea820-4197-7c7d-0990-7be06bf78aaf\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;8bdea820-4197-7c7d-0990-7be06bf78aaf&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</code></p><p><b>title</b>: Degradation Products</p><p><b>status</b>: active</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>method</b>: Degradation products by UHPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.2</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.3</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.3</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Individual unspecified degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.2</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Total degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-1.4</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf",
        "title" : "Degradation Products",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ]
        },
        "method" : {
          "text" : "Degradation products by UHPLC"
        },
        "qualifiedValue" : [
          {
            "appliesTo" : [
              {
                "text" : "Impurity 1"
              }
            ],
            "range" : //  could be a code 
            {
              "high" : {
                "value" : 0.2,
                "unit" : "% w/w",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          },
          {
            "appliesTo" : [
              {
                "text" : "Impurity 2"
              }
            ],
            "range" : {
              "high" : {
                "value" : 0.3,
                "unit" : "% w/w",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          },
          {
            "appliesTo" : [
              {
                "text" : "Impurity 3"
              }
            ],
            "range" : {
              "high" : {
                "value" : 0.3,
                "unit" : "% w/w",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          },
          {
            "appliesTo" : [
              {
                "text" : "Individual unspecified degradation products"
              }
            ],
            "range" : {
              "high" : {
                "value" : 0.2,
                "unit" : "% w/w",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          },
          {
            "appliesTo" : [
              {
                "text" : "Total degradation products"
              }
            ],
            "range" : {
              "high" : {
                "value" : 1.4,
                "unit" : "% w/w",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          }
        ],
        "component" : [
          {
            "code" : //  are expected to have a component that says what impurity this one is 
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:31e29d22-5fcb-546e-24fd-52a4a4004467",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "31e29d22-5fcb-546e-24fd-52a4a4004467",
        "text" : // Water
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_31e29d22-5fcb-546e-24fd-52a4a4004467\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"31e29d22-5fcb-546e-24fd-52a4a4004467\"> </a><a name=\"hc31e29d22-5fcb-546e-24fd-52a4a4004467\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;31e29d22-5fcb-546e-24fd-52a4a4004467&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>method</b>: USP &lt;921&gt; <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-1.0</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467",
        "title" : "Water Content",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "WaterContent",
              "display" : "Water Content"
            }
          ],
          "text" : "Water Content"
        },
        "method" : {
          "text" : "USP <921>"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "high" : {
                "value" : 1.0,
                "unit" : "% w/w",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:32e29d22-5fcb-546e-24fd-52a4a4004467",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "32e29d22-5fcb-546e-24fd-52a4a4004467",
        "text" : // LyophilizationWater
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_32e29d22-5fcb-546e-24fd-52a4a4004467\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"32e29d22-5fcb-546e-24fd-52a4a4004467\"> </a><a name=\"hc32e29d22-5fcb-546e-24fd-52a4a4004467\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;32e29d22-5fcb-546e-24fd-52a4a4004467&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>method</b>: USP &lt;921&gt; <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-1.2</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467",
        "title" : "Water Content",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "WaterContent",
              "display" : "Water Content"
            }
          ],
          "text" : "Water Content"
        },
        "method" : {
          "text" : "USP <921>"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "high" : {
                "value" : 1.2,
                "unit" : "% w/w",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:32e29d22-6fcb-546e-24fd-52a4a4004467",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "32e29d22-6fcb-546e-24fd-52a4a4004467",
        "text" : // LyophilizationWaterHomogeneity
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_32e29d22-6fcb-546e-24fd-52a4a4004467\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"32e29d22-6fcb-546e-24fd-52a4a4004467\"> </a><a name=\"hc32e29d22-6fcb-546e-24fd-52a4a4004467\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;32e29d22-6fcb-546e-24fd-52a4a4004467&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Moisture (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WWWH &quot;Water Content Homogeneity&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>-1.5-1.5 % w/w</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Do statistically significant effects <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SSE &quot;Statistically significant effects&quot;)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lower one-sided 95% confidence limit of Max Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#LCL)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Upper one-sided 95% confidence limit of Max Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#UCL)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Was Homogeneity demonstrated? <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Homogeneity &quot;Homogeneity demonstrated&quot;)</span></p></blockquote></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467",
        "title" : "Water Content",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "WWWH",
              "display" : "Water Content Homogeneity"
            }
          ],
          "text" : "Moisture (%)"
        },
        "qualifiedValue" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq",
                "valueString" : "± 1.4 % (w/w)"
              }
            ],
            "range" : {
              "low" : {
                "value" : -1.5,
                "unit" : "% w/w",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              },
              "high" : {
                "value" : 1.5,
                "unit" : "% w/w",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          }
        ],
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SSE",
                  "display" : "Statistically significant effects"
                }
              ],
              "text" : "Do statistically significant effects"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "LCL",
                  "display" : "Lower one-sided 95% confidence limit of Max Difference"
                }
              ],
              "text" : "Lower one-sided 95% confidence limit of Max Difference"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "UCL",
                  "display" : "Upper one-sided 95% confidence limit of Max Difference"
                }
              ],
              "text" : "Upper one-sided 95% confidence limit of Max Difference"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Homogeneity",
                  "display" : "Homogeneity demonstrated"
                }
              ],
              "text" : "Was Homogeneity demonstrated?"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:32e29d32-6fcb-546e-24fd-52a4a4004467",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "32e29d32-6fcb-546e-24fd-52a4a4004467",
        "text" : // LyophilizationAssayHomogeneity
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_32e29d32-6fcb-546e-24fd-52a4a4004467\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"32e29d32-6fcb-546e-24fd-52a4a4004467\"> </a><a name=\"hc32e29d32-6fcb-546e-24fd-52a4a4004467\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;32e29d32-6fcb-546e-24fd-52a4a4004467&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467</code></p><p><b>title</b>: Assay</p><p><b>status</b>: active</p><p><b>code</b>: Assay by HPLC (% Main Peak) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSH &quot;Assay Content Homogeneity&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>-2.3-2.3 %</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Do statistically significant effects <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SSE &quot;Statistically significant effects&quot;)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lower one-sided 95% confidence limit of Max Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#LCL)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Upper one-sided 95% confidence limit of Max Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#UCL)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Was Homogeneity demonstrated? <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Homogeneity &quot;Homogeneity demonstrated&quot;)</span></p></blockquote></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467",
        "title" : "Assay",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "ASSH",
              "display" : "Assay Content Homogeneity"
            }
          ],
          "text" : "Assay by HPLC (% Main Peak)"
        },
        "qualifiedValue" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq",
                "valueString" : "± 2.3%"
              }
            ],
            "range" : {
              "low" : {
                "value" : -2.3,
                "unit" : "%",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              },
              "high" : {
                "value" : 2.3,
                "unit" : "%",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          }
        ],
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SSE",
                  "display" : "Statistically significant effects"
                }
              ],
              "text" : "Do statistically significant effects"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "LCL",
                  "display" : "Lower one-sided 95% confidence limit of Max Difference"
                }
              ],
              "text" : "Lower one-sided 95% confidence limit of Max Difference"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "UCL",
                  "display" : "Upper one-sided 95% confidence limit of Max Difference"
                }
              ],
              "text" : "Upper one-sided 95% confidence limit of Max Difference"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Homogeneity",
                  "display" : "Homogeneity demonstrated"
                }
              ],
              "text" : "Was Homogeneity demonstrated?"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:ef17cff1-6586-a5a4-9168-2602140548d7",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "ef17cff1-6586-a5a4-9168-2602140548d7",
        "text" : // UniformityUSP
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_ef17cff1-6586-a5a4-9168-2602140548d7\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"ef17cff1-6586-a5a4-9168-2602140548d7\"> </a><a name=\"hcef17cff1-6586-a5a4-9168-2602140548d7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;ef17cff1-6586-a5a4-9168-2602140548d7&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d7</code></p><p><b>title</b>: Uniformity of Dosage Units, Weight Variation - Meets USP / Ph. Eur. requirements (% label claim)</p><p><b>status</b>: active</p><p><b>code</b>: Uniformity of Dosage Units, Weight Variation <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Uniformity of Dosage Units, Weight Variation)</span></p><p><b>method</b>: Weight variation <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>97-? %</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d7",
        "title" : "Uniformity of Dosage Units, Weight Variation - Meets USP / Ph. Eur. requirements (% label claim)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d7
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Uniformity of Dosage Units, Weight Variation",
              "display" : "Uniformity of Dosage Units, Weight Variation"
            }
          ],
          "text" : "Uniformity of Dosage Units, Weight Variation"
        },
        "method" : {
          "text" : "Weight variation"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "low" : {
                "value" : 97,
                "unit" : "%",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:ef17cff1-6586-a5a4-9168-2602140548d8",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "ef17cff1-6586-a5a4-9168-2602140548d8",
        "text" : // UniformityAcceptance
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_ef17cff1-6586-a5a4-9168-2602140548d8\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"ef17cff1-6586-a5a4-9168-2602140548d8\"> </a><a name=\"hcef17cff1-6586-a5a4-9168-2602140548d8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;ef17cff1-6586-a5a4-9168-2602140548d8&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d8</code></p><p><b>title</b>: Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV)</p><p><b>status</b>: active</p><p><b>code</b>: Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV))</span></p><p><b>method</b>: Weight variation <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-25</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d8",
        "title" : "Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d8
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV)",
              "display" : "Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV)"
            }
          ],
          "text" : "Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV)"
        },
        "method" : {
          "text" : "Weight variation"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "high" : //  what are units of acceptance value? 
              {
                "value" : 25
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:fc17b5d6-9fe1-91c2-2d06-47cb5b295e72",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "fc17b5d6-9fe1-91c2-2d06-47cb5b295e72",
        "text" : // releasepH
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc17b5d6-9fe1-91c2-2d06-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc17b5d6-9fe1-91c2-2d06-47cb5b295e72\"> </a><a name=\"hcfc17b5d6-9fe1-91c2-2d06-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc17b5d6-9fe1-91c2-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: pH (reconstituted)</p><p><b>status</b>: active</p><p><b>code</b>: pH (reconstituted) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH (reconstituted))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>6.95-7.05 pH</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d06-47cb5b295e72",
        "title" : "pH (reconstituted)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d06-47cb5b295e72
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "pH (reconstituted)",
              "display" : "pH (reconstituted)"
            }
          ],
          "text" : "pH (reconstituted)"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "low" : {
                "value" : 6.95,
                "unit" : "pH",
                "system" : "http://unitsofmeasure.org",
                "code" : "pH"
              },
              "high" : {
                "value" : 7.05,
                "unit" : "pH",
                "system" : "http://unitsofmeasure.org",
                "code" : "pH"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:22515a3c-5034-448a-9c19-938ce1958424",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "22515a3c-5034-448a-9c19-938ce1958424",
        "text" : // conclusion
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_22515a3c-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"22515a3c-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc22515a3c-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;22515a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Conclusion</p><p><b>status</b>: active</p><p><b>code</b>: Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#CONC)</span></p></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424",
        "title" : "Conclusion",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "CONC",
              "display" : "Conclusion"
            }
          ],
          "text" : "Conclusion"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:64505a3c-5034-448a-9c19-938ce1958424",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "64505a3c-5034-448a-9c19-938ce1958424",
        "text" : // TAMC
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64505a3c-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64505a3c-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc64505a3c-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64505a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: TAMC [a]</p><p><b>status</b>: active</p><p><b>code</b>: TAMC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#TAMC)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-10</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424",
        "title" : "TAMC [a]",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "TAMC",
              "display" : "TAMC"
            }
          ],
          "text" : "TAMC"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "high" : //  todo UCUM 
              {
                "value" : 10,
                "unit" : "CFU/100ml"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:64515a3c-5034-448a-9c19-938ce1958424",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "64515a3c-5034-448a-9c19-938ce1958424",
        "text" : // TYMC
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515a3c-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515a3c-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc64515a3c-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: TYMC [a]</p><p><b>status</b>: active</p><p><b>code</b>: TAMC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#TAMC)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-10</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424",
        "title" : "TYMC [a]",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "TAMC",
              "display" : "TAMC"
            }
          ],
          "text" : "TAMC"
        },
        "qualifiedValue" : [
          {
            "range" : {
              "high" : //  todo UCUM 
              {
                "value" : 10,
                "unit" : "CFU/100ml"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:64515a3c-5134-448a-9c19-938ce1958424",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "64515a3c-5134-448a-9c19-938ce1958424",
        "text" : // FillWeightAverage
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515a3c-5134-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515a3c-5134-448a-9c19-938ce1958424\"> </a><a name=\"hc64515a3c-5134-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515a3c-5134-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-938ce1958424</code></p><p><b>title</b>: Fill Weight Average</p><p><b>status</b>: active</p><p><b>code</b>: Fill Weight Average <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Fill Weight Average)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-938ce1958424",
        "title" : "Fill Weight Average",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-938ce1958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Fill Weight Average",
              "display" : "Fill Weight Average"
            }
          ]
        },
        "qualifiedValue" : [
          {
            "extension" : [
              //  todo probably want to just not have this, detect that, and show as N/A 
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                "valueString" : "N/A"
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:64525a3c-5134-448a-9c19-938ce1958424",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "64525a3c-5134-448a-9c19-938ce1958424",
        "text" : // FillWeightTarget
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64525a3c-5134-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64525a3c-5134-448a-9c19-938ce1958424\"> </a><a name=\"hc64525a3c-5134-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64525a3c-5134-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a3c-5134-448a-9c19-938ce1958424</code></p><p><b>title</b>: Fill Weight Target</p><p><b>status</b>: active</p><p><b>code</b>: Fill Weight Target (g) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Fill Weight Target (g))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/64525a3c-5134-448a-9c19-938ce1958424",
        "title" : "Fill Weight Target",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/64525a3c-5134-448a-9c19-938ce1958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Fill Weight Target (g)",
              "display" : "Fill Weight Target (g)"
            }
          ]
        },
        "qualifiedValue" : [
          {
            "extension" : [
              //  todo probably want to just not have this, detect that, and show as N/A 
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                "valueString" : "N/A"
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:64515a3c-5134-448a-9c29-938ce1958424",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "64515a3c-5134-448a-9c29-938ce1958424",
        "text" : // FillWeightAverageFromTarget
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515a3c-5134-448a-9c29-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515a3c-5134-448a-9c29-938ce1958424\"> </a><a name=\"hc64515a3c-5134-448a-9c29-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515a3c-5134-448a-9c29-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c29-938ce1958424</code></p><p><b>title</b>: Actual Avg. Weight from Target</p><p><b>status</b>: active</p><p><b>code</b>: Actual Avg. Weight from Target <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Actual Avg. Weight from Target)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>2-2 %</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c29-938ce1958424",
        "title" : "Actual Avg. Weight from Target",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c29-938ce1958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Actual Avg. Weight from Target",
              "display" : "Actual Avg. Weight from Target"
            }
          ]
        },
        "qualifiedValue" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq",
                "valueString" : "± 2% target (%)"
              }
            ],
            "range" : {
              "low" : {
                "value" : 2,
                "unit" : "%",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              },
              "high" : {
                "value" : 2,
                "unit" : "%",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:64515a3c-5234-448a-9c29-938ce1958424",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "64515a3c-5234-448a-9c29-938ce1958424",
        "text" : // HoldTimeFiltrationToFilling
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515a3c-5234-448a-9c29-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515a3c-5234-448a-9c29-938ce1958424\"> </a><a name=\"hc64515a3c-5234-448a-9c29-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515a3c-5234-448a-9c29-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5234-448a-9c29-938ce1958424</code></p><p><b>title</b>: Hold Time (filtration To filling)</p><p><b>status</b>: active</p><p><b>code</b>: Hold Time (filtration To filling) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Hold Time (filtration To filling))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-2.5</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5234-448a-9c29-938ce1958424",
        "title" : "Hold Time (filtration To filling)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/64515a3c-5234-448a-9c29-938ce1958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Hold Time (filtration To filling)",
              "display" : "Hold Time (filtration To filling)"
            }
          ]
        },
        "qualifiedValue" : [
          {
            "range" : {
              "high" : {
                "value" : 2.5,
                "unit" : "hours",
                "system" : "http://unitsofmeasure.org",
                "code" : "h"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:64515a3c-5334-448a-9c29-938ce1958424",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "64515a3c-5334-448a-9c29-938ce1958424",
        "text" : // HoldTimeFilling
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515a3c-5334-448a-9c29-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515a3c-5334-448a-9c29-938ce1958424\"> </a><a name=\"hc64515a3c-5334-448a-9c29-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515a3c-5334-448a-9c29-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5334-448a-9c29-938ce1958424</code></p><p><b>title</b>: Hold Time (start filling to end filling)</p><p><b>status</b>: active</p><p><b>code</b>: Hold Time (start filling to end filling) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Hold Time (start filling to end filling))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-1.25</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5334-448a-9c29-938ce1958424",
        "title" : "Hold Time (start filling to end filling)",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/64515a3c-5334-448a-9c29-938ce1958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Hold Time (start filling to end filling)",
              "display" : "Hold Time (start filling to end filling)"
            }
          ]
        },
        "qualifiedValue" : [
          {
            "range" : {
              "high" : {
                "value" : 1.25,
                "unit" : "hours",
                "system" : "http://unitsofmeasure.org",
                "code" : "h"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:64535a3c-5334-448a-9c29-938ce1958424",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "64535a3c-5334-448a-9c29-938ce1958424",
        "text" : // FilterIntegrity
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64535a3c-5334-448a-9c29-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64535a3c-5334-448a-9c29-938ce1958424\"> </a><a name=\"hc64535a3c-5334-448a-9c29-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64535a3c-5334-448a-9c29-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce1958424</code></p><p><b>title</b>: Filter Integrity Test</p><p><b>status</b>: active</p><p><b>code</b>: Filter Integrity Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Filter Integrity Test)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>3.5-? psi</td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce1958424",
        "title" : "Filter Integrity Test",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce1958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Filter Integrity Test",
              "display" : "Filter Integrity Test"
            }
          ]
        },
        "qualifiedValue" : [
          {
            "range" : {
              "low" : //  out of scope of ucum apparently 
              {
                "value" : 3.5,
                "unit" : "psi",
                "system" : "http://unitsofmeasure.org",
                "code" : "[psi]"
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:22525a3c-5034-448a-9c19-938ce1958424",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "22525a3c-5034-448a-9c19-938ce1958424",
        "text" : // LyophilizationConclusion
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_22525a3c-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"22525a3c-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc22525a3c-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;22525a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Conclusion</p><p><b>status</b>: active</p><p><b>code</b>: Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#CONC)</span></p></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424",
        "title" : "Conclusion",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "CONC",
              "display" : "Conclusion"
            }
          ],
          "text" : "Conclusion"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:64535a3c-5334-448a-9c29-938ce2958424",
      "resource" : // qualifiedValue>  
					
				</qualifiedValue
      {
        "resourceType" : "ObservationDefinition",
        "id" : "64535a3c-5334-448a-9c29-938ce2958424",
        "text" : // LyophilizerNumber
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64535a3c-5334-448a-9c29-938ce2958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64535a3c-5334-448a-9c29-938ce2958424\"> </a><a name=\"hc64535a3c-5334-448a-9c29-938ce2958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64535a3c-5334-448a-9c29-938ce2958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424</code></p><p><b>title</b>: Lyophilizer Number</p><p><b>status</b>: active</p><p><b>code</b>: Lyophilizer Number <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Lyophilizer Number)</span></p></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424",
        "title" : "Lyophilizer Number",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Lyophilizer Number",
              "display" : "Lyophilizer Number"
            }
          ]
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:22e7e672-40a6-4036-3c1f-b8ba6a7d045e",
      "resource" : {
        "resourceType" : "ObservationDefinition",
        "id" : "22e7e672-40a6-4036-3c1f-b8ba6a7d045e",
        "text" : // LyophilizationAssay
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_22e7e672-40a6-4036-3c1f-b8ba6a7d045e\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"22e7e672-40a6-4036-3c1f-b8ba6a7d045e\"> </a><a name=\"hc22e7e672-40a6-4036-3c1f-b8ba6a7d045e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;22e7e672-40a6-4036-3c1f-b8ba6a7d045e&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e</code></p><p><b>title</b>: Assay</p><p><b>status</b>: active</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>method</b>: Assay by UHPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>95-105 %</td></tr></table><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Number of Locations <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#LOC)</span></td></tr></table></div>"
        },
        "url" : "http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e",
        "title" : "Assay",
        "status" : "active",
        "code" : // http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "ASSAY",
              "display" : "Assay"
            }
          ],
          "text" : "Assay"
        },
        "method" : {
          "text" : "Assay by UHPLC"
        },
        "qualifiedValue" : [
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq",
                "valueString" : "95% to 105% of label claim"
              }
            ],
            "range" : {
              "low" : {
                "value" : 95,
                "unit" : "%",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              },
              "high" : {
                "value" : 105,
                "unit" : "%",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          }
        ],
        "component" : [
          {
            "code" : //  are expected to have a component that says number of locations 
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "LOC",
                  "display" : "Number of Locations"
                }
              ]
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51",
      "resource" : {
        "resourceType" : "Medication",
        "id" : "339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51",
        "meta" : // medication-batch-information-drug-pq-ex1
        {
          "profile" : [
            🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Medication-batch-information-drug-pq"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\"> </a><p><b>Generated Narrative: Medication</b><a name=\"339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\"> </a><a name=\"hc339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Medication-batch-information-drug-pq.html\">Medication - Batch Information Drug PQ</a></p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , , , , , </td><td>33445</td></tr></table></div>"
        },
        "code" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
              "valueReference" : {
                "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
              }
            }
          ]
        },
        "batch" : //  todo consider change this be the MID? 
        // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
        {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
              "extension" : [
                {
                  "url" : "manufacturingDate",
                  "valueDateTime" : "2020-06"
                },
                {
                  "url" : "batchQuantity",
                  "valueQuantity" : {
                    "value" : 100100,
                    "unit" : "tablets"
                  }
                },
                {
                  "url" : "batchUtilization",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                        "code" : "C133990",
                        "display" : "Commercial"
                      }
                    ],
                    "text" : "Production"
                  }
                },
                {
                  "url" : "assignedManufacturer",
                  "valueReference" : {
                    "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                  }
                },
                // Organization/organization-drug-pq-ex1
                {
                  "url" : "container",
                  "extension" : [
                    {
                      "url" : "closureSystemDescription",
                      "valueString" : "100 cc HDPE Bottle 2 g desiccant"
                    }
                  ]
                }
              ]
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
              "valueDateTime" : "2019-09-08"
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq",
              "valueCodeableConcept" : {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/batch-designation",
                    "code" : "maximum",
                    "display" : "Maximum"
                  }
                ],
                "text" : "Maximum"
              }
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq",
              "valuePositiveInt" : 3
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
              "valueReference" : {
                "reference" : "Substance/fc078762-81c5-5656-9744-13c7ad1e595b"
              }
            },
            // Substance/substance-drug-pq-ex1
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
              "valueDateTime" : "2020-08"
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
              "valueReference" : {
                "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
              }
            },
            // Organization/organization-drug-pq-ex1
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
              "valueQuantity" : {
                "value" : 4.81,
                "unit" : "kg"
              }
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq",
              "valueQuantity" : {
                "value" : 4.91,
                "unit" : "kg"
              }
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq",
              "valueQuantity" : {
                "value" : 30,
                "unit" : "g"
              }
            }
          ],
          "lotNumber" : "33445"
        }
      }
    },
    //  local extensions 
    {
      "fullUrl" : "urn:uuid:a9dfda53-734b-045f-7ae4-94a6281d53bc",
      "resource" : {
        "resourceType" : "Medication",
        "id" : "a9dfda53-734b-045f-7ae4-94a6281d53bc",
        "text" : // medication-actual-batch-2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\"> </a><p><b>Generated Narrative: Medication</b><a name=\"a9dfda53-734b-045f-7ae4-94a6281d53bc\"> </a><a name=\"hca9dfda53-734b-045f-7ae4-94a6281d53bc\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;a9dfda53-734b-045f-7ae4-94a6281d53bc&quot; </p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , , , , , </td><td>33446</td></tr></table></div>"
        },
        "code" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
              "valueReference" : {
                "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
              }
            }
          ]
        },
        "batch" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
        {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
              "extension" : [
                {
                  "url" : "manufacturingDate",
                  "valueDateTime" : "2020-06"
                },
                {
                  "url" : "batchQuantity",
                  "valueQuantity" : {
                    "value" : 100050,
                    "unit" : "tablets"
                  }
                },
                {
                  "url" : "batchUtilization",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                        "code" : "C185328",
                        "display" : "Stability Study"
                      }
                    ],
                    "text" : "PPQ / Stability"
                  }
                },
                {
                  "url" : "assignedManufacturer",
                  "valueReference" : {
                    "reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
                  }
                },
                // Organization/manufacturer
                {
                  "url" : "container",
                  "extension" : [
                    {
                      "url" : "closureSystemDescription",
                      "valueString" : "100 cc HDPE Bottle 2 g desiccant"
                    }
                  ]
                }
              ]
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
              "valueDateTime" : "2019-09-08"
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq",
              "valueCodeableConcept" : {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/batch-designation",
                    "code" : "maximum",
                    "display" : "Maximum"
                  }
                ],
                "text" : "Maximum"
              }
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq",
              "valuePositiveInt" : 4
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
              "valueReference" : {
                "reference" : "Substance/cb31d747-2338-88d5-342c-8e9c097e4dad"
              }
            },
            // Substance/actual-batch-substance-2
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
              "valueDateTime" : "2020-08"
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
              "valueReference" : {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
              }
            },
            // Organization/packaging
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
              "valueQuantity" : {
                "value" : 4.82,
                "unit" : "kg"
              }
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq",
              "valueQuantity" : {
                "value" : 4.92,
                "unit" : "kg"
              }
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq",
              "valueQuantity" : {
                "value" : 30,
                "unit" : "g"
              }
            }
          ],
          "lotNumber" : "33446"
        }
      }
    },
    //  local extensions 
    {
      "fullUrl" : "urn:uuid:c6f5fadd-62e6-3a01-93d9-b3b182f67d06",
      "resource" : {
        "resourceType" : "Medication",
        "id" : "c6f5fadd-62e6-3a01-93d9-b3b182f67d06",
        "text" : // medication-actual-batch-3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\"> </a><p><b>Generated Narrative: Medication</b><a name=\"c6f5fadd-62e6-3a01-93d9-b3b182f67d06\"> </a><a name=\"hcc6f5fadd-62e6-3a01-93d9-b3b182f67d06\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;c6f5fadd-62e6-3a01-93d9-b3b182f67d06&quot; </p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , , , , , </td><td>33447</td></tr></table></div>"
        },
        "code" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
              "valueReference" : {
                "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
              }
            }
          ]
        },
        "batch" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
        {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
              "extension" : [
                {
                  "url" : "manufacturingDate",
                  "valueDateTime" : "2020-06"
                },
                {
                  "url" : "batchQuantity",
                  "valueQuantity" : {
                    "value" : 100125,
                    "unit" : "tablets"
                  }
                },
                {
                  "url" : "batchUtilization",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                        "code" : "C185328",
                        "display" : "Stability Study"
                      }
                    ],
                    "text" : "PPQ / Stability"
                  }
                },
                {
                  "url" : "assignedManufacturer",
                  "valueReference" : {
                    "reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
                  }
                },
                // Organization/manufacturer
                {
                  "url" : "container",
                  "extension" : [
                    {
                      "url" : "closureSystemDescription",
                      "valueString" : "100 cc HDPE Bottle 2 g desiccant"
                    }
                  ]
                }
              ]
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
              "valueDateTime" : "2019-09-08"
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq",
              "valueCodeableConcept" : {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/batch-designation",
                    "code" : "maximum",
                    "display" : "Maximum"
                  }
                ],
                "text" : "Maximum"
              }
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
              "valueDateTime" : "2020-08"
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq",
              "valuePositiveInt" : 3
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
              "valueReference" : {
                "reference" : "Substance/1551f97b-6f6d-825e-1fb3-44b0b090808c"
              }
            },
            // Substance/actual-batch-substance-3
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
              "valueReference" : {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
              }
            },
            // Organization/packaging
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
              "valueQuantity" : {
                "value" : 4.83,
                "unit" : "kg"
              }
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq",
              "valueQuantity" : {
                "value" : 4.93,
                "unit" : "kg"
              }
            },
            {
              "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq",
              "valueQuantity" : {
                "value" : 30,
                "unit" : "g"
              }
            }
          ],
          "lotNumber" : "33447"
        }
      }
    },
    //  local exensions 
    {
      "fullUrl" : "urn:uuid:0102bca4-46c1-a6bf-1025-cd403fee710a",
      "resource" : {
        "resourceType" : "Organization",
        "id" : "0102bca4-46c1-a6bf-1025-cd403fee710a",
        "text" : // manufacturer
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_0102bca4-46c1-a6bf-1025-cd403fee710a\"> </a><p><b>Generated Narrative: Organization</b><a name=\"0102bca4-46c1-a6bf-1025-cd403fee710a\"> </a><a name=\"hc0102bca4-46c1-a6bf-1025-cd403fee710a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;0102bca4-46c1-a6bf-1025-cd403fee710a&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3010027650</p><p><b>active</b>: true</p><p><b>type</b>: Drug Product Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-product-manufacture)</span></p><p><b>name</b>: AAA Pharmaceutical, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>681 Main Street Lumberton New Jersey 08048 USA </td></tr></table></div>"
        },
        "identifier" : [
          {
            "system" : "urn:oid:2.16.840.1.113883.4.82",
            "value" : "3010027650"
          }
        ],
        "active" : true,
        "type" : [
          //  FDA establishment identifier 
          {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                "code" : "drug-product-manufacture",
                "display" : "Drug Product Manufacture"
              }
            ]
          }
        ],
        "name" : "AAA Pharmaceutical, Inc.",
        "contact" : [
          {
            "address" : {
              "line" : [
                "681 Main Street"
              ],
              "city" : "Lumberton",
              "state" : "New Jersey",
              "postalCode" : "08048",
              "country" : "USA"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b07",
      "resource" : {
        "resourceType" : "Organization",
        "id" : "378fbe5f-5926-3a5c-4c64-5428df877b07",
        "text" : // packaging
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_378fbe5f-5926-3a5c-4c64-5428df877b07\"> </a><p><b>Generated Narrative: Organization</b><a name=\"378fbe5f-5926-3a5c-4c64-5428df877b07\"> </a><a name=\"hc378fbe5f-5926-3a5c-4c64-5428df877b07\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;378fbe5f-5926-3a5c-4c64-5428df877b07&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3008816891</p><p><b>active</b>: true</p><p><b>type</b>: Packaging <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#packaging)</span></p><p><b>name</b>: MySite</p></div>"
        },
        "identifier" : [
          {
            "system" : "urn:oid:2.16.840.1.113883.4.82",
            "value" : "3008816891"
          }
        ],
        "active" : true,
        "type" : [
          {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                "code" : "packaging",
                "display" : "Packaging"
              }
            ]
          }
        ],
        "name" : "MySite"
      }
    },
    {
      "fullUrl" : "urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b08",
      "resource" : {
        "resourceType" : "Organization",
        "id" : "378fbe5f-5926-3a5c-4c64-5428df877b08",
        "text" : // testing lab
        // 378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a><p><b>Generated Narrative: Organization</b><a name=\"378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a><a name=\"hc378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;378fbe5f-5926-3a5c-4c64-5428df877b08&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3007270600</p><p><b>active</b>: true</p><p><b>type</b>: Analytical Testing - Release <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#analytical-testing-release)</span></p><p><b>name</b>: Testing Lab</p></div>"
        },
        "identifier" : [
          {
            "system" : "urn:oid:2.16.840.1.113883.4.82",
            "value" : "3007270600"
          }
        ],
        "active" : true,
        "type" : [
          {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                "code" : "analytical-testing-release",
                "display" : "Analytical Testing - Release"
              }
            ]
          }
        ],
        "name" : "Testing Lab"
      }
    },
    {
      "fullUrl" : "urn:uuid:b664977d-799d-a1ce-928a-5def2a9955bd",
      "resource" : {
        "resourceType" : "DiagnosticReport",
        "id" : "processValidationReport",
        "text" : //  ideally this wants a subject, but it can only be a Medication (batch) and we have multiple. 
                     however the observations themselves do have subjects 
        {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_processValidationReport\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"processValidationReport\"> </a><a name=\"hcprocessValidationReport\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport &quot;processValidationReport&quot; </p></div><p><b>Triggered by</b>: See on this page: PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</p><p><b>status</b>: final</p><p><b>code</b>: Process Validation Report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-report-type.html\">Pharmaceutical Report Type Codes</a>#Process Validation Report)</span></p><p><b>effective</b>: 2020-12</p><p><b>result</b>: </p><ul><li>See on this page: Observation/9c56948a-2a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-3a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-4a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-3a49-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56958a-4a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-5a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-2a39-6609-1c01-4d297ea57a33</li><li>See on this page: Observation/9c56948a-3a39-6619-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-4a39-6619-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-3a49-6619-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56958a-4a39-6619-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-5a39-6709-1c01-4d197ea57a33</li><li>See on this page: Observation/f0a04328-905c-4ec5-372e-4d6cfef18629</li><li>See on this page: Observation/5e5a5e67-7fc6-0064-1be9-5d9d14d887e5</li><li>See on this page: Observation/cfde6776-673c-72e2-68c4-07b77cd85b74</li><li>See on this page: Observation/9c56948a-1a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/1e20aed7-7626-1664-8d96-235f860d9a2c</li><li>See on this page: Observation/ec6d7e30-4d70-491b-0669-a613eedd3c60</li><li>See on this page: Observation/ab7997fa-7b46-1175-3f01-6f6997f7878a</li><li>See on this page: Observation/4052f28b-64a2-392d-35e4-ec8e912434d2</li><li>See on this page: Observation/34ebc51d-8105-0589-3c8d-e7aa6bd0a06c</li><li>See on this page: Observation/2940bf11-05bf-6ce2-3c64-457d0d1f9913</li><li>See on this page: Observation/332b1e76-6f70-2b4e-5d0c-f22a0e042d3e</li><li>See on this page: Observation/f0a13a3b-2e8b-594f-6874-6050511e4c57</li><li>See on this page: Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a795</li><li>See on this page: Observation/be016630-8754-7414-9014-21e020ad66c6</li><li>See on this page: Observation/92568f68-78f3-908c-6935-ff5f3d574dd6</li><li>See on this page: Observation/a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12</li><li>See on this page: Observation/d8533dcb-03f8-5997-6ccf-4f9b6f7a5745</li><li>See on this page: Observation/7cec19a2-34a7-6b80-3d60-083b2cc64fcb</li><li>See on this page: Observation/27aa47fd-7964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/6a78bcde-4781-226c-946e-a4b6915c1899</li><li>See on this page: Observation/f9f11088-7527-947c-3d3f-e71b32e13c78</li><li>See on this page: Observation/66c2f585-678e-78b8-2235-1a3b37bd6e46</li><li>See on this page: Observation/f8232d25-023d-679f-9c58-a6dc234b7a28</li><li>See on this page: Observation/368b82be-75dd-1d97-3dbc-a7eed9869daa</li><li>See on this page: Observation/44aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/45aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/45ab47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/37aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/38aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/38aa48fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/37aa47fd-7964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/47aa47fd-7964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/47aa47fd-7964-4f96-6495-b2bec7f160e8</li><li>See on this page: Observation/47aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/47aa47fd-8964-5f96-6495-b2bec7f160e7</li></ul><p><b>conclusion</b>: The samples have been assessed and the conclusion is...</p></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
            "valueReference" : {
              "reference" : "PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f"
            }
          }
        ],
        "status" : "final",
        "code" : // PlanDefinition/validationProtocol
        {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-report-type",
              "code" : "Process Validation Report",
              "display" : "Process Validation Report"
            }
          ]
        },
        "effectiveDateTime" : "2020-12",
        "result" : [
          {
            "reference" : "Observation/9c56948a-2a39-6609-1c01-4d197ea57a33"
          },
          // Observation/compoundingpHPre1
          {
            "reference" : "Observation/9c56948a-3a39-6609-1c01-4d197ea57a33"
          },
          // Observation/compoundingpHPre2
          {
            "reference" : "Observation/9c56948a-4a39-6609-1c01-4d197ea57a33"
          },
          // Observation/compoundingpHPre3
          {
            "reference" : "Observation/9c56948a-3a49-6609-1c01-4d197ea57a33"
          },
          // Observation/compoundingpHPost1
          {
            "reference" : "Observation/9c56958a-4a39-6609-1c01-4d197ea57a33"
          },
          // Observation/compoundingpHPost2
          {
            "reference" : "Observation/9c56948a-5a39-6609-1c01-4d197ea57a33"
          },
          // Observation/compoundingpHPost3
          {
            "reference" : "Observation/9c56948a-2a39-6609-1c01-4d297ea57a33"
          },
          // Observation/compoundingAssayPre1
          {
            "reference" : "Observation/9c56948a-3a39-6619-1c01-4d197ea57a33"
          },
          // Observation/compoundingAssayPre2
          {
            "reference" : "Observation/9c56948a-4a39-6619-1c01-4d197ea57a33"
          },
          // Observation/compoundingAssayPre3
          {
            "reference" : "Observation/9c56948a-3a49-6619-1c01-4d197ea57a33"
          },
          // Observation/compoundingAssayPost1
          {
            "reference" : "Observation/9c56958a-4a39-6619-1c01-4d197ea57a33"
          },
          // Observation/compoundingAssayPost2
          {
            "reference" : "Observation/9c56948a-5a39-6709-1c01-4d197ea57a33"
          },
          // Observation/compoundingAssayPost3
          {
            "reference" : "Observation/f0a04328-905c-4ec5-372e-4d6cfef18629"
          },
          // Observation/observationIdentification
          {
            "reference" : "Observation/5e5a5e67-7fc6-0064-1be9-5d9d14d887e5"
          },
          // Observation/observationIdentification2
          {
            "reference" : "Observation/cfde6776-673c-72e2-68c4-07b77cd85b74"
          },
          // Observation/observationIdentification3
          {
            "reference" : "Observation/9c56948a-1a39-6609-1c01-4d197ea57a33"
          },
          // Observation/observationAssay
          {
            "reference" : "Observation/1e20aed7-7626-1664-8d96-235f860d9a2c"
          },
          // Observation/observationAssay2
          {
            "reference" : "Observation/ec6d7e30-4d70-491b-0669-a613eedd3c60"
          },
          // Observation/observationAssay3
          {
            "reference" : "Observation/ab7997fa-7b46-1175-3f01-6f6997f7878a"
          },
          // Observation/observationDegradation-imp1
          {
            "reference" : "Observation/4052f28b-64a2-392d-35e4-ec8e912434d2"
          },
          // Observation/observationDegradation-imp1-2
          {
            "reference" : "Observation/34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"
          },
          // Observation/observationDegradation-imp1-3
          {
            "reference" : "Observation/2940bf11-05bf-6ce2-3c64-457d0d1f9913"
          },
          // Observation/observationDegradation-imp2
          {
            "reference" : "Observation/332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"
          },
          // Observation/observationDegradation-imp2-2
          {
            "reference" : "Observation/f0a13a3b-2e8b-594f-6874-6050511e4c57"
          },
          // Observation/observationDegradation-imp2-3
          {
            "reference" : "Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a795"
          },
          // Observation/observationDegradation-imp3
          {
            "reference" : "Observation/be016630-8754-7414-9014-21e020ad66c6"
          },
          // Observation/observationDegradation-imp3-2
          {
            "reference" : "Observation/92568f68-78f3-908c-6935-ff5f3d574dd6"
          },
          // Observation/observationDegradation-imp3-3
          {
            "reference" : "Observation/a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"
          },
          // Observation/observationDegradation-imp-unspecified
          {
            "reference" : "Observation/d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"
          },
          // Observation/observationDegradation-imp-unspecified-2
          {
            "reference" : "Observation/7cec19a2-34a7-6b80-3d60-083b2cc64fcb"
          },
          // Observation/observationDegradation-imp-unspecified-3
          {
            "reference" : "Observation/27aa47fd-7964-4f96-6495-b2bec7f160e7"
          },
          // Observation/observationDegradation-imp-total
          {
            "reference" : "Observation/6a78bcde-4781-226c-946e-a4b6915c1899"
          },
          // Observation/observationDegradation-imp-total-2
          {
            "reference" : "Observation/f9f11088-7527-947c-3d3f-e71b32e13c78"
          },
          // Observation/observationDegradation-imp-total-3
          {
            "reference" : "Observation/66c2f585-678e-78b8-2235-1a3b37bd6e46"
          },
          // Observation/observationWater
          {
            "reference" : "Observation/f8232d25-023d-679f-9c58-a6dc234b7a28"
          },
          // Observation/observationWater2
          {
            "reference" : "Observation/368b82be-75dd-1d97-3dbc-a7eed9869daa"
          },
          // Observation/observationWater3
          {
            "reference" : "Observation/44aa47fd-8964-4f96-6495-b2bec7f160e7"
          },
          // Observation/fillingTAMC1
          {
            "reference" : "Observation/45aa47fd-8964-4f96-6495-b2bec7f160e7"
          },
          // Observation/fillingConclusion-nosubject
          {
            "reference" : "Observation/45ab47fd-8964-4f96-6495-b2bec7f160e7"
          },
          // Observation/lyophilizationConclusion-nosubject
          {
            "reference" : "Observation/37aa47fd-8964-4f96-6495-b2bec7f160e7"
          },
          // Observation/lyophilizerNumber1
          {
            "reference" : "Observation/38aa47fd-8964-4f96-6495-b2bec7f160e7"
          },
          // Observation/lyophilizerNumber2
          {
            "reference" : "Observation/38aa48fd-8964-4f96-6495-b2bec7f160e7"
          },
          // Observation/lyophilizerNumber3
          {
            "reference" : "Observation/37aa47fd-7964-4f96-6495-b2bec7f160e7"
          },
          // Observation/lyophilizationAssay1
          {
            "reference" : "Observation/47aa47fd-7964-4f96-6495-b2bec7f160e7"
          },
          // Observation/lyophilizationAssay2
          {
            "reference" : "Observation/47aa47fd-7964-4f96-6495-b2bec7f160e8"
          },
          // Observation/lyophilizationAssay3
          {
            "reference" : "Observation/47aa47fd-8964-4f96-6495-b2bec7f160e7"
          },
          // Observation/lyophilizerWaterHomogeneity1
          {
            "reference" : "Observation/47aa47fd-8964-5f96-6495-b2bec7f160e7"
          }
        ],
        "conclusion" : "The samples have been assessed and the conclusion is..."
      }
    },
    // Observation/lyophilizerAssayHomogeneity1
    {
      "fullUrl" : "urn:uuid:f0a04328-905c-4ec5-372e-4d6cfef18629",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "f0a04328-905c-4ec5-372e-4d6cfef18629",
        "text" : // observationIdentification
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f0a04328-905c-4ec5-372e-4d6cfef18629\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f0a04328-905c-4ec5-372e-4d6cfef18629\"> </a><a name=\"hcf0a04328-905c-4ec5-372e-4d6cfef18629\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;f0a04328-905c-4ec5-372e-4d6cfef18629&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Identification
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "IDT",
              "display" : "Identification"
            }
          ],
          "text" : "Identification"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "text" : "Complies"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:5e5a5e67-7fc6-0064-1be9-5d9d14d887e5",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "5e5a5e67-7fc6-0064-1be9-5d9d14d887e5",
        "text" : // observationIdentification2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_5e5a5e67-7fc6-0064-1be9-5d9d14d887e5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"5e5a5e67-7fc6-0064-1be9-5d9d14d887e5\"> </a><a name=\"hc5e5a5e67-7fc6-0064-1be9-5d9d14d887e5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;5e5a5e67-7fc6-0064-1be9-5d9d14d887e5&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Does not comply <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Identification
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "IDT",
              "display" : "Identification"
            }
          ],
          "text" : "Identification"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "text" : "Does not comply"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:cfde6776-673c-72e2-68c4-07b77cd85b74",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "cfde6776-673c-72e2-68c4-07b77cd85b74",
        "text" : // observationIdentification3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_cfde6776-673c-72e2-68c4-07b77cd85b74\"> </a><p><b>Generated Narrative: Observation</b><a name=\"cfde6776-673c-72e2-68c4-07b77cd85b74\"> </a><a name=\"hccfde6776-673c-72e2-68c4-07b77cd85b74\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;cfde6776-673c-72e2-68c4-07b77cd85b74&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Identification
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "IDT",
              "display" : "Identification"
            }
          ],
          "text" : "Identification"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "text" : "Complies"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-2a39-6609-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-2a39-6609-1c01-4d197ea57a33",
        "text" : // compoundingpHPre1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-2a39-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-2a39-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-2a39-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-2a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 6.91 pH<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code pH = 'pH')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingpHPre
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "pH (adjustment of pre-clarification bulk solution)",
              "display" : "pH (adjustment of pre-clarification bulk solution)"
            }
          ],
          "text" : "pH (adjustment of pre-clarification bulk solution)"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 6.91,
          "unit" : "pH",
          "system" : "http://unitsofmeasure.org",
          "code" : "pH"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-3a39-6609-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-3a39-6609-1c01-4d197ea57a33",
        "text" : // compoundingpHPre2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-3a39-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-3a39-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-3a39-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-3a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 6.92 pH<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code pH = 'pH')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingpHPre
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "pH (adjustment of pre-clarification bulk solution)",
              "display" : "pH (adjustment of pre-clarification bulk solution)"
            }
          ],
          "text" : "pH (adjustment of pre-clarification bulk solution)"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 6.92,
          "unit" : "pH",
          "system" : "http://unitsofmeasure.org",
          "code" : "pH"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-4a39-6609-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-4a39-6609-1c01-4d197ea57a33",
        "text" : // compoundingpHPre3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-4a39-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-4a39-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-4a39-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-4a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 6.93 pH<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code pH = 'pH')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingpHPre
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "pH (adjustment of pre-clarification bulk solution)",
              "display" : "pH (adjustment of pre-clarification bulk solution)"
            }
          ],
          "text" : "pH (adjustment of pre-clarification bulk solution)"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 6.93,
          "unit" : "pH",
          "system" : "http://unitsofmeasure.org",
          "code" : "pH"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-3a49-6609-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-3a49-6609-1c01-4d197ea57a33",
        "text" : // compoundingpHPost1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-3a49-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-3a49-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-3a49-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-3a49-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 7.01 pH<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code pH = 'pH')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingpHPost
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "pH (adjustment of pre-clarification bulk solution)",
              "display" : "pH (adjustment of pre-clarification bulk solution)"
            }
          ],
          "text" : "pH (adjustment of pre-clarification bulk solution)"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 7.01,
          "unit" : "pH",
          "system" : "http://unitsofmeasure.org",
          "code" : "pH"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56958a-4a39-6609-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56958a-4a39-6609-1c01-4d197ea57a33",
        "text" : // compoundingpHPost2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56958a-4a39-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56958a-4a39-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56958a-4a39-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56958a-4a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 7.02 pH<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code pH = 'pH')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingpHPost
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "pH (adjustment of pre-clarification bulk solution)",
              "display" : "pH (adjustment of pre-clarification bulk solution)"
            }
          ],
          "text" : "pH (adjustment of pre-clarification bulk solution)"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 7.02,
          "unit" : "pH",
          "system" : "http://unitsofmeasure.org",
          "code" : "pH"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-5a39-6609-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-5a39-6609-1c01-4d197ea57a33",
        "text" : // compoundingpHPost3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-5a39-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-5a39-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-5a39-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-5a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 6.93 pH<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code pH = 'pH')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingpHPost
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "pH (adjustment of pre-clarification bulk solution)",
              "display" : "pH (adjustment of pre-clarification bulk solution)"
            }
          ],
          "text" : "pH (adjustment of pre-clarification bulk solution)"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 6.93,
          "unit" : "pH",
          "system" : "http://unitsofmeasure.org",
          "code" : "pH"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-2a39-6609-1c01-4d297ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-2a39-6609-1c01-4d297ea57a33",
        "text" : // compoundingAssayPre1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-2a39-6609-1c01-4d297ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-2a39-6609-1c01-4d297ea57a33\"> </a><a name=\"hc9c56948a-2a39-6609-1c01-4d297ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-2a39-6609-1c01-4d297ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Assay (pre-clarification filtration) (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Assay (pre-clarification filtration) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 21.1 mg/mL<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingAssayPre
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Assay (pre-clarification filtration) (mg/mL)",
              "display" : "Assay (pre-clarification filtration) (mg/mL)"
            }
          ],
          "text" : "Assay (pre-clarification filtration) (mg/mL)"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 21.1,
          "unit" : "mg/mL",
          "system" : "http://unitsofmeasure.org",
          "code" : "mg/mL"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-3a39-6619-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-3a39-6619-1c01-4d197ea57a33",
        "text" : // compoundingAssayPre2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-3a39-6619-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-3a39-6619-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-3a39-6619-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-3a39-6619-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Assay (pre-clarification filtration) (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Assay (pre-clarification filtration) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 21.2 mg/mL<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingAssayPre
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Assay (pre-clarification filtration) (mg/mL)",
              "display" : "Assay (pre-clarification filtration) (mg/mL)"
            }
          ],
          "text" : "Assay (pre-clarification filtration) (mg/mL)"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 21.2,
          "unit" : "mg/mL",
          "system" : "http://unitsofmeasure.org",
          "code" : "mg/mL"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-4a39-6619-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-4a39-6619-1c01-4d197ea57a33",
        "text" : // compoundingAssayPre3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-4a39-6619-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-4a39-6619-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-4a39-6619-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-4a39-6619-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Assay (pre-clarification filtration) (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Assay (pre-clarification filtration) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 21.3 mg/mL<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingAssayPre
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Assay (pre-clarification filtration) (mg/mL)",
              "display" : "Assay (pre-clarification filtration) (mg/mL)"
            }
          ],
          "text" : "Assay (pre-clarification filtration) (mg/mL)"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 21.3,
          "unit" : "mg/mL",
          "system" : "http://unitsofmeasure.org",
          "code" : "mg/mL"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-3a49-6619-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-3a49-6619-1c01-4d197ea57a33",
        "text" : // compoundingAssayPost1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-3a49-6619-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-3a49-6619-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-3a49-6619-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-3a49-6619-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: Assay (Post dilution bulk solution) (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Assay (Post dilution bulk solution) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 20.1 mg/mL<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingAssayPost
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Assay (Post dilution bulk solution) (mg/mL)",
              "display" : "Assay (Post dilution bulk solution) (mg/mL)"
            }
          ],
          "text" : "Assay (Post dilution bulk solution) (mg/mL)"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 20.1,
          "unit" : "mg/mL",
          "system" : "http://unitsofmeasure.org",
          "code" : "mg/mL"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56958a-4a39-6619-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56958a-4a39-6619-1c01-4d197ea57a33",
        "text" : // compoundingAssayPost2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56958a-4a39-6619-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56958a-4a39-6619-1c01-4d197ea57a33\"> </a><a name=\"hc9c56958a-4a39-6619-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56958a-4a39-6619-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: Assay (Post dilution bulk solution) (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Assay (Post dilution bulk solution) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 20.2 mg/mL<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingAssayPost
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Assay (Post dilution bulk solution) (mg/mL)",
              "display" : "Assay (Post dilution bulk solution) (mg/mL)"
            }
          ],
          "text" : "Assay (Post dilution bulk solution) (mg/mL)"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 20.2,
          "unit" : "mg/mL",
          "system" : "http://unitsofmeasure.org",
          "code" : "mg/mL"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-5a39-6709-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-5a39-6709-1c01-4d197ea57a33",
        "text" : // compoundingAssayPost3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-5a39-6709-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-5a39-6709-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-5a39-6709-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-5a39-6709-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: Assay (Post dilution bulk solution) (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Assay (Post dilution bulk solution) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 20.3 mg/mL<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"
        },
        "status" : "final",
        "code" : // ObservationDefinition/compoundingAssayPost
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Assay (Post dilution bulk solution) (mg/mL)",
              "display" : "Assay (Post dilution bulk solution) (mg/mL)"
            }
          ],
          "text" : "Assay (Post dilution bulk solution) (mg/mL)"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 20.3,
          "unit" : "mg/mL",
          "system" : "http://unitsofmeasure.org",
          "code" : "mg/mL"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:9c56948a-1a39-6609-1c01-4d197ea57a33",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "9c56948a-1a39-6609-1c01-4d197ea57a33",
        "text" : // observationAssay
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-1a39-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-1a39-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-1a39-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-1a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 103 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Assay
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "ASSAY",
              "display" : "Assay"
            }
          ],
          "text" : "Assay"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 103,
          "unit" : "%",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:1e20aed7-7626-1664-8d96-235f860d9a2c",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "1e20aed7-7626-1664-8d96-235f860d9a2c",
        "text" : // observationAssay2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_1e20aed7-7626-1664-8d96-235f860d9a2c\"> </a><p><b>Generated Narrative: Observation</b><a name=\"1e20aed7-7626-1664-8d96-235f860d9a2c\"> </a><a name=\"hc1e20aed7-7626-1664-8d96-235f860d9a2c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;1e20aed7-7626-1664-8d96-235f860d9a2c&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 102 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Assay
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "ASSAY",
              "display" : "Assay"
            }
          ],
          "text" : "Assay"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 102,
          "unit" : "%",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:ec6d7e30-4d70-491b-0669-a613eedd3c60",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "ec6d7e30-4d70-491b-0669-a613eedd3c60",
        "text" : // observationAssay3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ec6d7e30-4d70-491b-0669-a613eedd3c60\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ec6d7e30-4d70-491b-0669-a613eedd3c60\"> </a><a name=\"hcec6d7e30-4d70-491b-0669-a613eedd3c60\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;ec6d7e30-4d70-491b-0669-a613eedd3c60&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 101 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Assay
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "ASSAY",
              "display" : "Assay"
            }
          ],
          "text" : "Assay"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 101,
          "unit" : "%",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:ab7997fa-7b46-1175-3f01-6f6997f7878a",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "ab7997fa-7b46-1175-3f01-6f6997f7878a",
        "text" : // observationDegradation-imp1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ab7997fa-7b46-1175-3f01-6f6997f7878a\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ab7997fa-7b46-1175-3f01-6f6997f7878a\"> </a><a name=\"hcab7997fa-7b46-1175-3f01-6f6997f7878a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;ab7997fa-7b46-1175-3f01-6f6997f7878a&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.1,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Impurity 1"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:4052f28b-64a2-392d-35e4-ec8e912434d2",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "4052f28b-64a2-392d-35e4-ec8e912434d2",
        "text" : // observationDegradation-imp1-2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_4052f28b-64a2-392d-35e4-ec8e912434d2\"> </a><p><b>Generated Narrative: Observation</b><a name=\"4052f28b-64a2-392d-35e4-ec8e912434d2\"> </a><a name=\"hc4052f28b-64a2-392d-35e4-ec8e912434d2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;4052f28b-64a2-392d-35e4-ec8e912434d2&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.2,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Impurity 1"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:34ebc51d-8105-0589-3c8d-e7aa6bd0a06c",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "34ebc51d-8105-0589-3c8d-e7aa6bd0a06c",
        "text" : // observationDegradation-imp1-3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_34ebc51d-8105-0589-3c8d-e7aa6bd0a06c\"> </a><p><b>Generated Narrative: Observation</b><a name=\"34ebc51d-8105-0589-3c8d-e7aa6bd0a06c\"> </a><a name=\"hc34ebc51d-8105-0589-3c8d-e7aa6bd0a06c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;34ebc51d-8105-0589-3c8d-e7aa6bd0a06c&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.2,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Impurity 1"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:2940bf11-05bf-6ce2-3c64-457d0d1f9913",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "2940bf11-05bf-6ce2-3c64-457d0d1f9913",
        "text" : // observationDegradation-imp2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_2940bf11-05bf-6ce2-3c64-457d0d1f9913\"> </a><p><b>Generated Narrative: Observation</b><a name=\"2940bf11-05bf-6ce2-3c64-457d0d1f9913\"> </a><a name=\"hc2940bf11-05bf-6ce2-3c64-457d0d1f9913\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;2940bf11-05bf-6ce2-3c64-457d0d1f9913&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.2,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Impurity 2"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:332b1e76-6f70-2b4e-5d0c-f22a0e042d3e",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "332b1e76-6f70-2b4e-5d0c-f22a0e042d3e",
        "text" : // observationDegradation-imp2-2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_332b1e76-6f70-2b4e-5d0c-f22a0e042d3e\"> </a><p><b>Generated Narrative: Observation</b><a name=\"332b1e76-6f70-2b4e-5d0c-f22a0e042d3e\"> </a><a name=\"hc332b1e76-6f70-2b4e-5d0c-f22a0e042d3e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;332b1e76-6f70-2b4e-5d0c-f22a0e042d3e&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.2,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Impurity 2"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:f0a13a3b-2e8b-594f-6874-6050511e4c57",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "f0a13a3b-2e8b-594f-6874-6050511e4c57",
        "text" : // observationDegradation-imp2-3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f0a13a3b-2e8b-594f-6874-6050511e4c57\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f0a13a3b-2e8b-594f-6874-6050511e4c57\"> </a><a name=\"hcf0a13a3b-2e8b-594f-6874-6050511e4c57\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;f0a13a3b-2e8b-594f-6874-6050511e4c57&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.2,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Impurity 2"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:7fe7ccd7-6449-0186-2282-3eeb4cf6a795",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "7fe7ccd7-6449-0186-2282-3eeb4cf6a795",
        "text" : // observationDegradation-imp3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_7fe7ccd7-6449-0186-2282-3eeb4cf6a795\"> </a><p><b>Generated Narrative: Observation</b><a name=\"7fe7ccd7-6449-0186-2282-3eeb4cf6a795\"> </a><a name=\"hc7fe7ccd7-6449-0186-2282-3eeb4cf6a795\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;7fe7ccd7-6449-0186-2282-3eeb4cf6a795&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.2,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Impurity 3"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:be016630-8754-7414-9014-21e020ad66c6",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "be016630-8754-7414-9014-21e020ad66c6",
        "text" : // observationDegradation-imp3-2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_be016630-8754-7414-9014-21e020ad66c6\"> </a><p><b>Generated Narrative: Observation</b><a name=\"be016630-8754-7414-9014-21e020ad66c6\"> </a><a name=\"hcbe016630-8754-7414-9014-21e020ad66c6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;be016630-8754-7414-9014-21e020ad66c6&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.2,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Impurity 3"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:92568f68-78f3-908c-6935-ff5f3d574dd6",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "92568f68-78f3-908c-6935-ff5f3d574dd6",
        "text" : // observationDegradation-imp3-3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_92568f68-78f3-908c-6935-ff5f3d574dd6\"> </a><p><b>Generated Narrative: Observation</b><a name=\"92568f68-78f3-908c-6935-ff5f3d574dd6\"> </a><a name=\"hc92568f68-78f3-908c-6935-ff5f3d574dd6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;92568f68-78f3-908c-6935-ff5f3d574dd6&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.2,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Impurity 3"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12",
        "text" : // observationDegradation-imp-unspecified
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12\"> </a><p><b>Generated Narrative: Observation</b><a name=\"a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12\"> </a><a name=\"hca0ba0f6d-8ec0-846a-a70d-f6bca6d01a12\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Individual unspecified degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.1,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Individual unspecified degradation products"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:d8533dcb-03f8-5997-6ccf-4f9b6f7a5745",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "d8533dcb-03f8-5997-6ccf-4f9b6f7a5745",
        "text" : // observationDegradation-imp-unspecified-2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_d8533dcb-03f8-5997-6ccf-4f9b6f7a5745\"> </a><p><b>Generated Narrative: Observation</b><a name=\"d8533dcb-03f8-5997-6ccf-4f9b6f7a5745\"> </a><a name=\"hcd8533dcb-03f8-5997-6ccf-4f9b6f7a5745\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;d8533dcb-03f8-5997-6ccf-4f9b6f7a5745&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Individual unspecified degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.1,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Individual unspecified degradation products"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:7cec19a2-34a7-6b80-3d60-083b2cc64fcb",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "7cec19a2-34a7-6b80-3d60-083b2cc64fcb",
        "text" : // observationDegradation-imp-unspecified-3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_7cec19a2-34a7-6b80-3d60-083b2cc64fcb\"> </a><p><b>Generated Narrative: Observation</b><a name=\"7cec19a2-34a7-6b80-3d60-083b2cc64fcb\"> </a><a name=\"hc7cec19a2-34a7-6b80-3d60-083b2cc64fcb\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;7cec19a2-34a7-6b80-3d60-083b2cc64fcb&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Individual unspecified degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.1,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Individual unspecified degradation products"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:27aa47fd-7964-4f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "27aa47fd-7964-4f96-6495-b2bec7f160e7",
        "text" : // observationDegradation-imp-total
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_27aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"27aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc27aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;27aa47fd-7964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.6 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.6,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Total degradation products"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:6a78bcde-4781-226c-946e-a4b6915c1899",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "6a78bcde-4781-226c-946e-a4b6915c1899",
        "text" : // observationDegradation-imp-total-2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_6a78bcde-4781-226c-946e-a4b6915c1899\"> </a><p><b>Generated Narrative: Observation</b><a name=\"6a78bcde-4781-226c-946e-a4b6915c1899\"> </a><a name=\"hc6a78bcde-4781-226c-946e-a4b6915c1899\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;6a78bcde-4781-226c-946e-a4b6915c1899&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.7 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.7,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Total degradation products"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:f9f11088-7527-947c-3d3f-e71b32e13c78",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "f9f11088-7527-947c-3d3f-e71b32e13c78",
        "text" : // observationDegradation-imp-total-3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f9f11088-7527-947c-3d3f-e71b32e13c78\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f9f11088-7527-947c-3d3f-e71b32e13c78\"> </a><a name=\"hcf9f11088-7527-947c-3d3f-e71b32e13c78\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;f9f11088-7527-947c-3d3f-e71b32e13c78&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.6 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Degradation
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "DGP",
              "display" : "Degradation Products"
            }
          ],
          "text" : "Degradation Products"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.6,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IMP",
                  "display" : "Impurity"
                }
              ]
            },
            "valueCodeableConcept" : {
              "text" : "Total degradation products"
            }
          }
        ]
      }
    },
    //  could have the code of an impurity substance, or could have an extension to point to it as a resource 
    {
      "fullUrl" : "urn:uuid:66c2f585-678e-78b8-2235-1a3b37bd6e46",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "66c2f585-678e-78b8-2235-1a3b37bd6e46",
        "text" : // observationWater
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_66c2f585-678e-78b8-2235-1a3b37bd6e46\"> </a><p><b>Generated Narrative: Observation</b><a name=\"66c2f585-678e-78b8-2235-1a3b37bd6e46\"> </a><a name=\"hc66c2f585-678e-78b8-2235-1a3b37bd6e46\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;66c2f585-678e-78b8-2235-1a3b37bd6e46&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.5 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Water
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "WaterContent",
              "display" : "Water Content"
            }
          ],
          "text" : "Water Content"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.5,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:f8232d25-023d-679f-9c58-a6dc234b7a28",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "f8232d25-023d-679f-9c58-a6dc234b7a28",
        "text" : // observationWater2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f8232d25-023d-679f-9c58-a6dc234b7a28\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f8232d25-023d-679f-9c58-a6dc234b7a28\"> </a><a name=\"hcf8232d25-023d-679f-9c58-a6dc234b7a28\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;f8232d25-023d-679f-9c58-a6dc234b7a28&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.5 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Water
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "WaterContent",
              "display" : "Water Content"
            }
          ],
          "text" : "Water Content"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.5,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:368b82be-75dd-1d97-3dbc-a7eed9869daa",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "368b82be-75dd-1d97-3dbc-a7eed9869daa",
        "text" : // observationWater3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_368b82be-75dd-1d97-3dbc-a7eed9869daa\"> </a><p><b>Generated Narrative: Observation</b><a name=\"368b82be-75dd-1d97-3dbc-a7eed9869daa\"> </a><a name=\"hc368b82be-75dd-1d97-3dbc-a7eed9869daa\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;368b82be-75dd-1d97-3dbc-a7eed9869daa&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.5 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"
        },
        "status" : "final",
        "code" : // ObservationDefinition/Water
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "WaterContent",
              "display" : "Water Content"
            }
          ],
          "text" : "Water Content"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 0.5,
          "unit" : "% w/w",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:44aa47fd-8964-4f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "44aa47fd-8964-4f96-6495-b2bec7f160e7",
        "text" : // fillingTAMC1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc44aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: TAMC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#TAMC)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 9.1 CFU/100ml</p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424"
        },
        "status" : "final",
        "code" : // ObservationDefinition/TAMC
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "TAMC",
              "display" : "TAMC"
            }
          ],
          "text" : "TAMC"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        //  todo UCUM 
        {
          "value" : 9.1,
          "unit" : "CFU/100ml"
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:45aa47fd-8964-4f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "45aa47fd-8964-4f96-6495-b2bec7f160e7",
        "text" : // fillingConclusion-nosubject
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_45aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"45aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc45aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;45aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#CONC)</span></p><p><b>subject</b>: <span>: all batches</span></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Conclusion of filling tests....</p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424"
        },
        "status" : "final",
        "code" : // ObservationDefinition/conclusion
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "CONC",
              "display" : "Conclusion"
            }
          ],
          "text" : "Conclusion"
        },
        "subject" : //  no subject because it applies to all the samples 
        {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/data-absent-reason",
              "valueCode" : "unsupported"
            }
          ],
          "display" : "all batches"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueString" : "Conclusion of filling tests...."
      }
    },
    // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
    {
      "fullUrl" : "urn:uuid:45ab47fd-8964-4f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "45ab47fd-8964-4f96-6495-b2bec7f160e7",
        "text" : //  no subject 
        // lyophilizationConclusion-nosubject
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_45ab47fd-8964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"45ab47fd-8964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc45ab47fd-8964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;45ab47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#CONC)</span></p><p><b>subject</b>: <span>: all batches</span></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Conclusion of lyophilization tests....</p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424"
        },
        "status" : "final",
        "code" : // ObservationDefinition/LyophilizationConclusion
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "CONC",
              "display" : "Conclusion"
            }
          ],
          "text" : "Conclusion"
        },
        "subject" : //  no subject because it applies to all the samples 
        {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/data-absent-reason",
              "valueCode" : "unsupported"
            }
          ],
          "display" : "all batches"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueString" : "Conclusion of lyophilization tests...."
      }
    },
    // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
    {
      "fullUrl" : "urn:uuid:37aa47fd-8964-4f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "37aa47fd-8964-4f96-6495-b2bec7f160e7",
        "text" : // lyophilizerNumber1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_37aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"37aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc37aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;37aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Lyophilizer Number &quot;Lyophilizer Number&quot;)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1234</p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424"
        },
        "status" : "final",
        "code" : // ObservationDefinition/LyophilizerNumber
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Lyophilizer Number",
              "display" : "Lyophilizer Number"
            }
          ],
          "text" : "Assay"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 1234
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:38aa47fd-8964-4f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "38aa47fd-8964-4f96-6495-b2bec7f160e7",
        "text" : // lyophilizerNumber2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_38aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"38aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc38aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;38aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Lyophilizer Number &quot;Lyophilizer Number&quot;)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1235</p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424"
        },
        "status" : "final",
        "code" : // ObservationDefinition/LyophilizerNumber
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Lyophilizer Number",
              "display" : "Lyophilizer Number"
            }
          ],
          "text" : "Assay"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 1235
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:38aa48fd-8964-4f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "38aa48fd-8964-4f96-6495-b2bec7f160e7",
        "text" : // lyophilizerNumber3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_38aa48fd-8964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"38aa48fd-8964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc38aa48fd-8964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;38aa48fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Lyophilizer Number &quot;Lyophilizer Number&quot;)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1236</p></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424"
        },
        "status" : "final",
        "code" : // ObservationDefinition/LyophilizerNumber
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Lyophilizer Number",
              "display" : "Lyophilizer Number"
            }
          ],
          "text" : "Assay"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 1236
        }
      }
    },
    {
      "fullUrl" : "urn:uuid:37aa47fd-7964-4f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "37aa47fd-7964-4f96-6495-b2bec7f160e7",
        "text" : // lyophilizationAssay1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_37aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"37aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc37aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;37aa47fd-7964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 97 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Number of Locations <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#LOC)</span></td><td>3</td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e"
        },
        "status" : "final",
        "code" : // ObservationDefinition/LyophilizationAssay
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "ASSAY",
              "display" : "Assay"
            }
          ],
          "text" : "Assay"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 97,
          "unit" : "%",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "LOC",
                  "display" : "Number of Locations"
                }
              ]
            },
            "valueInteger" : 3
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:47aa47fd-7964-4f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "47aa47fd-7964-4f96-6495-b2bec7f160e7",
        "text" : // lyophilizationAssay2
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_47aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"47aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc47aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;47aa47fd-7964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 98 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Number of Locations <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#LOC)</span></td><td>4</td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e"
        },
        "status" : "final",
        "code" : // ObservationDefinition/LyophilizationAssay
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "ASSAY",
              "display" : "Assay"
            }
          ],
          "text" : "Assay"
        },
        "subject" : {
          "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-2
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 98,
          "unit" : "%",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "LOC",
                  "display" : "Number of Locations"
                }
              ]
            },
            "valueInteger" : 4
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:47aa47fd-7964-4f96-6495-b2bec7f160e8",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "47aa47fd-7964-4f96-6495-b2bec7f160e8",
        "text" : // lyophilizationAssay3
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_47aa47fd-7964-4f96-6495-b2bec7f160e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"47aa47fd-7964-4f96-6495-b2bec7f160e8\"> </a><a name=\"hc47aa47fd-7964-4f96-6495-b2bec7f160e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;47aa47fd-7964-4f96-6495-b2bec7f160e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 96 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Number of Locations <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#LOC)</span></td><td>2</td></tr></table></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e"
        },
        "status" : "final",
        "code" : // ObservationDefinition/LyophilizationAssay
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "ASSAY",
              "display" : "Assay"
            }
          ],
          "text" : "Assay"
        },
        "subject" : {
          "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-actual-batch-3
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "value" : 96,
          "unit" : "%",
          "system" : "http://unitsofmeasure.org",
          "code" : "%"
        },
        "component" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "LOC",
                  "display" : "Number of Locations"
                }
              ]
            },
            "valueInteger" : 2
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:47aa47fd-8964-4f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "47aa47fd-8964-4f96-6495-b2bec7f160e7",
        "text" : // lyophilizerWaterHomogeneity1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_47aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"47aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc47aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;47aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Lyophilization Water Homogeneity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Lyophilization Water Homogeneity)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Do statistically significant effects <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SSE &quot;Statistically significant effects&quot;)</span></p><p><b>value</b>: Yes</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lower one-sided 95% confidence limit of Max Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#LCL)</span></p><p><b>value</b>: 0.8 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Upper one-sided 95% confidence limit of Max Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#UCL)</span></p><p><b>value</b>: 0.9 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Was Homogeneity demonstrated? <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Homogeneity &quot;Homogeneity demonstrated&quot;)</span></p><p><b>value</b>: Yes</p></blockquote></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467"
        },
        "status" : "final",
        "code" : // ObservationDefinition/LyophilizationWaterHomogeneity
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Lyophilization Water Homogeneity",
              "display" : "Lyophilization Water Homogeneity"
            }
          ],
          "text" : "Lyophilization Water Homogeneity"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "component" : [
          // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SSE",
                  "display" : "Statistically significant effects"
                }
              ],
              "text" : "Do statistically significant effects"
            },
            "valueString" : "Yes"
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "LCL",
                  "display" : "Lower one-sided 95% confidence limit of Max Difference"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 0.8,
              "unit" : "%"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "UCL",
                  "display" : "Upper one-sided 95% confidence limit of Max Difference"
                }
              ],
              "text" : "Upper one-sided 95% confidence limit of Max Difference"
            },
            "valueQuantity" : {
              "value" : 0.9,
              "unit" : "%"
            }
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Homogeneity",
                  "display" : "Homogeneity demonstrated"
                }
              ],
              "text" : "Was Homogeneity demonstrated?"
            },
            "valueString" : "Yes"
          }
        ]
      }
    },
    //  boolean? 
    {
      "fullUrl" : "urn:uuid:47aa47fd-8964-5f96-6495-b2bec7f160e7",
      "resource" : {
        "resourceType" : "Observation",
        "id" : "47aa47fd-8964-5f96-6495-b2bec7f160e7",
        "text" : // lyophilizerAssayHomogeneity1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_47aa47fd-8964-5f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"47aa47fd-8964-5f96-6495-b2bec7f160e7\"> </a><a name=\"hc47aa47fd-8964-5f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;47aa47fd-8964-5f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Lyophilization Assay Homogeneity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Lyophilization Assay Homogeneity)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Do statistically significant effects <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SSE &quot;Statistically significant effects&quot;)</span></p><p><b>value</b>: No</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lower one-sided 95% confidence limit of Max Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#LCL)</span></p><p><b>value</b>: Not calculated</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Upper one-sided 95% confidence limit of Max Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#UCL)</span></p><p><b>value</b>: Not calculated</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Was Homogeneity demonstrated? <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Homogeneity &quot;Homogeneity demonstrated&quot;)</span></p><p><b>value</b>: Yes</p></blockquote></div>"
        },
        "instantiatesReference" : {
          "reference" : "ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467"
        },
        "status" : "final",
        "code" : // ObservationDefinition/LyophilizationAssayHomogeneity
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
              "code" : "Lyophilization Assay Homogeneity",
              "display" : "Lyophilization Assay Homogeneity"
            }
          ],
          "text" : "Lyophilization Assay Homogeneity"
        },
        "subject" : {
          "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
        },
        "effectiveDateTime" : "2023-01-01T12:00:00Z",
        "performer" : [
          // Medication/medication-batch-information-drug-pq-ex1
          {
            "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
          }
        ],
        "component" : [
          // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SSE",
                  "display" : "Statistically significant effects"
                }
              ],
              "text" : "Do statistically significant effects"
            },
            "valueString" : "No"
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "LCL",
                  "display" : "Lower one-sided 95% confidence limit of Max Difference"
                }
              ]
            },
            "valueString" : "Not calculated"
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "UCL",
                  "display" : "Upper one-sided 95% confidence limit of Max Difference"
                }
              ],
              "text" : "Upper one-sided 95% confidence limit of Max Difference"
            },
            "valueString" : "Not calculated"
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Homogeneity",
                  "display" : "Homogeneity demonstrated"
                }
              ],
              "text" : "Was Homogeneity demonstrated?"
            },
            "valueString" : "Yes"
          }
        ]
      }
    },
    //  boolean? 
    {
      "fullUrl" : "urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5",
      "resource" : //  Section 1.1 - DP Identification 
      {
        "resourceType" : "MedicinalProductDefinition",
        "id" : "a0694a7a-aafa-4cbe-8135-c788a9a4d3d5",
        "text" : // medicinalproductdefinition-drug-product-pq-ex1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicinalProductDefinition_a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a><p><b>Generated Narrative: MedicinalProductDefinition</b><a name=\"a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a><a name=\"hca0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicinalProductDefinition &quot;a0694a7a-aafa-4cbe-8135-c788a9a4d3d5&quot; </p></div><p><b>description</b>: Textual description of the product</p><p><b>combinedPharmaceuticalDoseForm</b>: Gastro-resistant tablet <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterms.edqm.eu#10225000)</span></p><p><b>route</b>: Oral use <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterms.edqm.eu#20053000)</span></p><blockquote><p><b>name</b></p><p><b>productName</b>: Stelbat Tablets, 20mg</p><p><b>type</b>: Proprietary <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-productNameType-pq-example.html\">Product Name Type - example</a>#Proprietary)</span></p><h3>Parts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Part</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>20mg</td><td>Strength part <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-medicinal-product-name-part-type.html\">Product Name Part Type</a>#StrengthPart)</span></td></tr></table></blockquote></div>"
        },
        "description" : "Textual description of the product",
        "combinedPharmaceuticalDoseForm" : {
          "coding" : [
            {
              "system" : "http://standardterms.edqm.eu",
              "code" : "10225000",
              "display" : "Gastro-resistant tablet"
            }
          ]
        },
        "route" : [
          {
            "coding" : [
              {
                "system" : "http://standardterms.edqm.eu",
                "code" : "20053000",
                "display" : "Oral use"
              }
            ]
          }
        ],
        "name" : [
          {
            "productName" : "Stelbat Tablets, 20mg",
            "type" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-productNameType-pq-example",
                  "code" : "Proprietary",
                  "display" : "Proprietary"
                }
              ]
            },
            "part" : [
              {
                "part" : "20mg",
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/medicinal-product-name-part-type",
                      "code" : "StrengthPart",
                      "display" : "Strength part"
                    }
                  ]
                }
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d6",
      "resource" : {
        "resourceType" : "Ingredient",
        "id" : "a0694a7a-aafa-4cbe-8135-c788a9a4d3d6",
        "text" : // productIngredient
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_a0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a><p><b>Generated Narrative: Ingredient</b><a name=\"a0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a><a name=\"hca0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Ingredient &quot;a0694a7a-aafa-4cbe-8135-c788a9a4d3d6&quot; </p></div><p><b>status</b>: active</p><p><b>for</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>role</b>: Active <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-ingredient-role.html\">Ingredient Role</a>#100000072072)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/6eb94d34-48b4-5bb0-4c05-e183d2ea3e95</td></tr></table></blockquote></div>"
        },
        "status" : "active",
        "for" : [
          {
            "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
          }
        ],
        "role" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
        {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/ingredient-role",
              "code" : "100000072072",
              "display" : "Active"
            }
          ]
        },
        "substance" : {
          "code" : {
            "reference" : {
              "reference" : "SubstanceDefinition/6eb94d34-48b4-5bb0-4c05-e183d2ea3e95"
            }
          }
        }
      }
    },
    // SubstanceDefinition/substance1
    {
      "fullUrl" : "urn:uuid:6eb94d34-48b4-5bb0-4c05-e183d2ea3e95",
      "resource" : {
        "resourceType" : "SubstanceDefinition",
        "id" : "6eb94d34-48b4-5bb0-4c05-e183d2ea3e95",
        "text" : // substance1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_6eb94d34-48b4-5bb0-4c05-e183d2ea3e95\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"6eb94d34-48b4-5bb0-4c05-e183d2ea3e95\"> </a><a name=\"hc6eb94d34-48b4-5bb0-4c05-e183d2ea3e95\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;6eb94d34-48b4-5bb0-4c05-e183d2ea3e95&quot; </p></div><p><b>manufacturer</b>: See on this page: Organization/23dbbd32-2962-9fc3-40b1-67e864f21cd2</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table></div>"
        },
        "manufacturer" : [
          {
            "reference" : "Organization/23dbbd32-2962-9fc3-40b1-67e864f21cd2"
          }
        ],
        "name" : [
          // Organization/substance-manufacturer
          {
            "name" : "Stelbatolol"
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:23dbbd32-2962-9fc3-40b1-67e864f21cd2",
      "resource" : {
        "resourceType" : "Organization",
        "id" : "23dbbd32-2962-9fc3-40b1-67e864f21cd2",
        "text" : // substance-manufacturer
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_23dbbd32-2962-9fc3-40b1-67e864f21cd2\"> </a><p><b>Generated Narrative: Organization</b><a name=\"23dbbd32-2962-9fc3-40b1-67e864f21cd2\"> </a><a name=\"hc23dbbd32-2962-9fc3-40b1-67e864f21cd2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;23dbbd32-2962-9fc3-40b1-67e864f21cd2&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
        },
        "identifier" : [
          {
            "system" : "urn:oid:2.16.840.1.113883.4.82",
            "value" : "3003040516"
          }
        ],
        "active" : true,
        "type" : [
          //  FDA establishment identifier 
          {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                "code" : "drug-substance-manufacture",
                "display" : "Drug Substance Manufacture"
              }
            ]
          }
        ],
        "name" : "AAA Molybdenum Products, Inc.",
        "contact" : [
          {
            "address" : {
              "line" : [
                "7233 W 116th Pl",
                "Ste C"
              ],
              "city" : "Broomfield",
              "state" : "Colorado",
              "postalCode" : "80020",
              "country" : "USA"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:57a9af63-315d-1585-a261-0e337b289390",
      "resource" : {
        "resourceType" : "SubstanceDefinition",
        "id" : "57a9af63-315d-1585-a261-0e337b289390",
        "meta" : // substancedefinition-component-substance-drug-pq-ex1
        {
          "profile" : [
            🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SubstanceDefinition-component-substance-drug-pq"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_57a9af63-315d-1585-a261-0e337b289390\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"57a9af63-315d-1585-a261-0e337b289390\"> </a><a name=\"hc57a9af63-315d-1585-a261-0e337b289390\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;57a9af63-315d-1585-a261-0e337b289390&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-SubstanceDefinition-component-substance-drug-pq.html\">SubstanceDefinition - Component Substance Drug PQ</a></p></div><p><b>manufacturer</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table></div>"
        },
        "manufacturer" : [
          {
            "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
          }
        ],
        "name" : [
          // Organization/organization-drug-pq-ex1
          {
            "name" : "Stelbatolol"
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:49d2f0c0-4b28-9271-8aaf-2996a8b9739c",
      "resource" : {
        "resourceType" : "Organization",
        "id" : "49d2f0c0-4b28-9271-8aaf-2996a8b9739c",
        "meta" : // id value="substance-manufacturer"/
        // organization-drug-pq-ex1
        {
          "profile" : [
            🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Organization-drug-pq"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_49d2f0c0-4b28-9271-8aaf-2996a8b9739c\"> </a><p><b>Generated Narrative: Organization</b><a name=\"49d2f0c0-4b28-9271-8aaf-2996a8b9739c\"> </a><a name=\"hc49d2f0c0-4b28-9271-8aaf-2996a8b9739c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;49d2f0c0-4b28-9271-8aaf-2996a8b9739c&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Organization-drug-pq.html\">Organization - Drug PQ</a></p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
        },
        "identifier" : [
          {
            "system" : "urn:oid:2.16.840.1.113883.4.82",
            "value" : "3003040516"
          }
        ],
        "active" : true,
        "type" : [
          //  FDA establishment identifier 
          {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                "code" : "drug-substance-manufacture",
                "display" : "Drug Substance Manufacture"
              }
            ]
          }
        ],
        "name" : "AAA Molybdenum Products, Inc.",
        "contact" : [
          {
            "address" : {
              "line" : [
                "7233 W 116th Pl",
                "Ste C"
              ],
              "city" : "Broomfield",
              "state" : "Colorado",
              "postalCode" : "80020",
              "country" : "USA"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:bf6b038b-1334-3dd4-a552-65c169e2265a",
      "resource" : //  another outer action can be the whole thing, if needed 
      //  removed the main actions for brevity (see manufacturing example) 
      {
        "resourceType" : "PlanDefinition",
        "id" : "plandefinition-drug-pq-ex2-manufacturing-plan",
        "meta" : //  indicate this is as subset of the resource. In practice it would have it all 
        {
          "profile" : [
            🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PlanDefinition-drug-pq"
          ],
          "tag" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/v3-ObservationValue",
              "code" : "SUBSETTED"
            }
          ]
        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_plandefinition-drug-pq-ex2-manufacturing-plan\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"plandefinition-drug-pq-ex2-manufacturing-plan\"> </a><a name=\"hcplandefinition-drug-pq-ex2-manufacturing-plan\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition &quot;plandefinition-drug-pq-ex2-manufacturing-plan&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-PlanDefinition-drug-pq.html\">PlanDefinition - Drug PQ</a></p><p style=\"margin-bottom: 0px\">Tag: <span title=\"{http://terminology.hl7.org/CodeSystem/v3-ObservationValue http://terminology.hl7.org/CodeSystem/v3-ObservationValue}\">http://terminology.hl7.org/CodeSystem/v3-ObservationValue</span></p></div><p><b>Extension - History of Process PQ</b>: This can be text about the history</p><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a</code></p><p><b>title</b>: Process 1.0</p><p><b>type</b>: Workflow Definition <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-plan-definition-type.html\">PlanDefinitionType</a>#workflow-definition; <a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#manufacturing-process &quot;Manufacturing Process&quot;)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>description</b>: Narrative description of manufacturing process (5)</p><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-pH</blockquote><p><b>category</b>: Physical Property <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-test-category.html\">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - pH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>priority</b>: Critical <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-goalPriority-pq-example.html\">Goal Priority - example</a>#critical)</span></p><h3>Targets</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>pH must be in range 6.9 to 7.1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH &quot;pH&quot;)</span></td><td>6.9-7.1 pH</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-water-content</blockquote><p><b>category</b>: Physical Property <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-test-category.html\">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>priority</b>: Critical <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-goalPriority-pq-example.html\">Goal Priority - example</a>#critical)</span></p><h3>Targets</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Under 2% <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent &quot;Water content&quot;)</span></td><td>?-2</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-particle-size</blockquote><p><b>category</b>: Physical Property <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-test-category.html\">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - Particle Size <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>priority</b>: Critical <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-goalPriority-pq-example.html\">Goal Priority - example</a>#critical)</span></p><h3>Targets</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Under 200 microns <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#particle-size &quot;Particle Size&quot;)</span></td><td>?-200</td></tr></table></blockquote><blockquote><p><b>actor</b></p><h3>Options</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>TypeReference</b></td><td><b>Role</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: DeviceDefinition/82a39a18-91cf-a29d-76c1-a9e8bad9494d</td><td>Mixing Vessel <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-manufacturing-equipment-class.html\">Pharmaceutical Manufacturing Equipment Class Codes</a>#mixing-vessel)</span></td></tr></table></blockquote><blockquote><p><b>actor</b></p><h3>Options</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>TypeReference</b></td><td><b>Role</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: DeviceDefinition/82a39a18-91cf-b29d-76c1-a9e8bad9494d</td><td>Receiving Vessel <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-manufacturing-equipment-class.html\">Pharmaceutical Manufacturing Equipment Class Codes</a>#receiving-vessel)</span></td></tr></table></blockquote></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-history-of-process-pq",
            "valueMarkdown" : "This can be text about the history"
          }
        ],
        "url" : "http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a",
        "title" : "Process 1.0",
        "type" : // http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a
        {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/plan-definition-type",
              "code" : "workflow-definition",
              "display" : "Workflow Definition"
            },
            {
              "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
              "code" : "manufacturing-process",
              "display" : "Manufacturing Process"
            }
          ]
        },
        "status" : "active",
        "subjectReference" : {
          "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
        },
        "description" : "Narrative description of manufacturing process (5)",
        "goal" : [
          // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
          {
            "id" : "goal-control-pH",
            "category" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category",
                  "code" : "C123456",
                  "display" : "Physical Property"
                }
              ]
            },
            "description" : //  this is mandatory, even though we don't really want it 
            {
              "text" : "Controls - pH"
            },
            "priority" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example",
                  "code" : "critical",
                  "display" : "Critical"
                }
              ]
            },
            "target" : [
              {
                "measure" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "pH",
                      "display" : "pH"
                    }
                  ],
                  "text" : "pH must be in range 6.9 to 7.1"
                },
                "detailRange" : // detailString value="can also be a string"
                {
                  "low" : {
                    "value" : 6.9,
                    "unit" : "pH"
                  },
                  "high" : {
                    "value" : 7.1,
                    "unit" : "pH"
                  }
                }
              }
            ]
          },
          {
            "id" : "goal-control-water-content",
            "category" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category",
                  "code" : "C123456",
                  "display" : "Physical Property"
                }
              ]
            },
            "description" : //  this is mandatory, even though we don't really want it 
            {
              "text" : "Controls - Water Content"
            },
            "priority" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example",
                  "code" : "critical",
                  "display" : "Critical"
                }
              ]
            },
            "target" : [
              {
                "measure" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "WaterContent",
                      "display" : "Water content"
                    }
                  ],
                  "text" : "Under 2%"
                },
                "detailRange" : // detailString value="can also be a string"
                {
                  "high" : {
                    "value" : 2,
                    "unit" : "%"
                  }
                }
              }
            ]
          },
          {
            "id" : "goal-control-particle-size",
            "category" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category",
                  "code" : "C123456",
                  "display" : "Physical Property"
                }
              ]
            },
            "description" : {
              "text" : "Controls - Particle Size"
            },
            "priority" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example",
                  "code" : "critical",
                  "display" : "Critical"
                }
              ]
            },
            "target" : [
              {
                "measure" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "particle-size",
                      "display" : "Particle Size"
                    }
                  ],
                  "text" : "Under 200 microns"
                },
                "detailRange" : // detailString value="can also be a string"
                {
                  "high" : {
                    "value" : 200,
                    "unit" : "microns"
                  }
                }
              }
            ]
          }
        ],
        "actor" : [
          {
            "option" : [
              {
                "typeReference" : {
                  "reference" : "DeviceDefinition/82a39a18-91cf-a29d-76c1-a9e8bad9494d"
                },
                "role" : // DeviceDefinition/mixing-vessel
                {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-manufacturing-equipment-class",
                      "code" : "mixing-vessel",
                      "display" : "Mixing Vessel"
                    }
                  ]
                }
              }
            ]
          },
          {
            "option" : [
              {
                "typeReference" : {
                  "reference" : "DeviceDefinition/82a39a18-91cf-b29d-76c1-a9e8bad9494d"
                },
                "role" : // DeviceDefinition/receiving-tank
                {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-manufacturing-equipment-class",
                      "code" : "receiving-vessel",
                      "display" : "Receiving Vessel"
                    }
                  ]
                }
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:82a39a18-91cf-a29d-76c1-a9e8bad9494d",
      "resource" : {
        "resourceType" : "DeviceDefinition",
        "id" : "82a39a18-91cf-a29d-76c1-a9e8bad9494d",
        "text" : // mixing-vessel
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DeviceDefinition_82a39a18-91cf-a29d-76c1-a9e8bad9494d\"> </a><p><b>Generated Narrative: DeviceDefinition</b><a name=\"82a39a18-91cf-a29d-76c1-a9e8bad9494d\"> </a><a name=\"hc82a39a18-91cf-a29d-76c1-a9e8bad9494d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DeviceDefinition &quot;82a39a18-91cf-a29d-76c1-a9e8bad9494d&quot; </p></div><h3>DeviceNames</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>Mixing Vessel</td><td>registered-name</td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>Mixing Vessel <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-deviceType-pq-example.html\">Device Type - example</a>#mixing-vessel)</span></td></tr></table><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Capacity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-device-property.html\">Device Property Codes</a>#Capacity)</span></td><td>1000 litres</td></tr></table></div>"
        },
        "deviceName" : [
          {
            "name" : "Mixing Vessel",
            "type" : "registered-name"
          }
        ],
        "classification" : [
          {
            "type" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-deviceType-pq-example",
                  "code" : "mixing-vessel",
                  "display" : "Mixing Vessel"
                }
              ]
            }
          }
        ],
        "property" : [
          {
            "type" : {
              "coding" : [
                //  seems a little different to "maximum capacity 
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/device-property",
                  "code" : "Capacity",
                  "display" : "Capacity"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 1000,
              "unit" : "litres"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:82a39a18-91cf-b29d-76c1-a9e8bad9494d",
      "resource" : {
        "resourceType" : "DeviceDefinition",
        "id" : "82a39a18-91cf-b29d-76c1-a9e8bad9494d",
        "text" : // receiving-tank
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DeviceDefinition_82a39a18-91cf-b29d-76c1-a9e8bad9494d\"> </a><p><b>Generated Narrative: DeviceDefinition</b><a name=\"82a39a18-91cf-b29d-76c1-a9e8bad9494d\"> </a><a name=\"hc82a39a18-91cf-b29d-76c1-a9e8bad9494d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DeviceDefinition &quot;82a39a18-91cf-b29d-76c1-a9e8bad9494d&quot; </p></div><h3>DeviceNames</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>Receiving Tank</td><td>registered-name</td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>Receiving Tank <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-deviceType-pq-example.html\">Device Type - example</a>#receiving-tank)</span></td></tr></table><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Capacity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-device-property.html\">Device Property Codes</a>#Capacity)</span></td><td>1200 litres</td></tr></table></div>"
        },
        "deviceName" : [
          {
            "name" : "Receiving Tank",
            "type" : "registered-name"
          }
        ],
        "classification" : [
          {
            "type" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-deviceType-pq-example",
                  "code" : "receiving-tank",
                  "display" : "Receiving Tank"
                }
              ]
            }
          }
        ],
        "property" : [
          {
            "type" : {
              "coding" : [
                //  seems a little different to "maximum capacity 
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/device-property",
                  "code" : "Capacity",
                  "display" : "Capacity"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 1200,
              "unit" : "litres"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:fc078762-81c5-5656-9744-13c7ad1e595b",
      "resource" : {
        "resourceType" : "Substance",
        "id" : "fc078762-81c5-5656-9744-13c7ad1e595b",
        "meta" : // <id value="actual-batch-substance"/>
        // substance-drug-pq-ex1
        {
          "profile" : [
            🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Substance-drug-pq"
          ]
        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_fc078762-81c5-5656-9744-13c7ad1e595b\"> </a><p><b>Generated Narrative: Substance</b><a name=\"fc078762-81c5-5656-9744-13c7ad1e595b\"> </a><a name=\"hcfc078762-81c5-5656-9744-13c7ad1e595b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;fc078762-81c5-5656-9744-13c7ad1e595b&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Substance-drug-pq.html\">Substance - Drug PQ</a></p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT1</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
            "extension" : [
              {
                "url" : "manufacturingDate",
                "valueDateTime" : "2019-09-07"
              },
              {
                "url" : "batchQuantity",
                "valueQuantity" : {
                  "value" : 5,
                  "unit" : "kg"
                }
              },
              {
                "url" : "batchUtilization",
                "valueCodeableConcept" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C133991",
                      "display" : "Development"
                    }
                  ]
                }
              },
              {
                "url" : "assignedManufacturer",
                "valueReference" : {
                  "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                }
              }
            ]
          },
          // Organization/organization-drug-pq-ex1
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
            "valueDateTime" : "2019-09-08"
          },
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
            "valueDateTime" : "2022-09-08"
          },
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
            "valueQuantity" : {
              "value" : 4.8,
              "unit" : "kg"
            }
          }
        ],
        "identifier" : [
          //  local extensions 
          {
            "value" : "CAT1"
          }
        ],
        "instance" : true,
        "code" : {
          "reference" : {
            "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
          }
        }
      }
    },
    // SubstanceDefinition/substancedefinition-component-substance-drug-pq-ex1
    {
      "fullUrl" : "urn:uuid:cb31d747-2338-88d5-342c-8e9c097e4dad",
      "resource" : {
        "resourceType" : "Substance",
        "id" : "cb31d747-2338-88d5-342c-8e9c097e4dad",
        "text" : // actual-batch-substance-2
        {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_cb31d747-2338-88d5-342c-8e9c097e4dad\"> </a><p><b>Generated Narrative: Substance</b><a name=\"cb31d747-2338-88d5-342c-8e9c097e4dad\"> </a><a name=\"hccb31d747-2338-88d5-342c-8e9c097e4dad\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;cb31d747-2338-88d5-342c-8e9c097e4dad&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT2</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
            "extension" : [
              {
                "url" : "manufacturingDate",
                "valueDateTime" : "2019-09-07"
              },
              {
                "url" : "batchQuantity",
                "valueQuantity" : {
                  "value" : 5,
                  "unit" : "kg"
                }
              },
              {
                "url" : "batchUtilization",
                "valueCodeableConcept" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C133991",
                      "display" : "Development"
                    }
                  ]
                }
              },
              {
                "url" : "assignedManufacturer",
                "valueReference" : {
                  "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                }
              }
            ]
          },
          // Organization/organization-drug-pq-ex1
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
            "valueDateTime" : "2019-09-08"
          },
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
            "valueDateTime" : "2022-09-08"
          },
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
            "valueQuantity" : {
              "value" : 4.8,
              "unit" : "kg"
            }
          }
        ],
        "identifier" : [
          //  local extensions 
          {
            "value" : "CAT2"
          }
        ],
        "instance" : true,
        "code" : {
          "reference" : {
            "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
          }
        }
      }
    },
    // SubstanceDefinition/substancedefinition-component-substance-drug-pq-ex1
    {
      "fullUrl" : "urn:uuid:1551f97b-6f6d-825e-1fb3-44b0b090808c",
      "resource" : {
        "resourceType" : "Substance",
        "id" : "1551f97b-6f6d-825e-1fb3-44b0b090808c",
        "text" : // actual-batch-substance-3
        {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_1551f97b-6f6d-825e-1fb3-44b0b090808c\"> </a><p><b>Generated Narrative: Substance</b><a name=\"1551f97b-6f6d-825e-1fb3-44b0b090808c\"> </a><a name=\"hc1551f97b-6f6d-825e-1fb3-44b0b090808c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;1551f97b-6f6d-825e-1fb3-44b0b090808c&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT3</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
            "extension" : [
              {
                "url" : "manufacturingDate",
                "valueDateTime" : "2019-09-07"
              },
              {
                "url" : "batchQuantity",
                "valueQuantity" : {
                  "value" : 5,
                  "unit" : "kg"
                }
              },
              {
                "url" : "batchUtilization",
                "valueCodeableConcept" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C133991",
                      "display" : "Development"
                    }
                  ]
                }
              },
              {
                "url" : "assignedManufacturer",
                "valueReference" : {
                  "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                }
              }
            ]
          },
          // Organization/organization-drug-pq-ex1
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
            "valueDateTime" : "2019-09-08"
          },
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
            "valueDateTime" : "2022-09-08"
          },
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
            "valueQuantity" : {
              "value" : 4.8,
              "unit" : "kg"
            }
          }
        ],
        "identifier" : [
          //  local extensions 
          {
            "value" : "CAT3"
          }
        ],
        "instance" : true,
        "code" : {
          "reference" : {
            "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
          }
        }
      }
    }
  ]
}