Pharmaceutical Quality (Industry)
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Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions

: Example: Bundle - Manufacturing, substance - JSON Representation

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//  Product Manufacturing 
{
  "resourceType" : "Bundle",
  "id" : "bundle-product-manufacturing-pq-ex2-sub",
  "meta" : {
    "profile" : [
      🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-product-manufacturing-pq"
    ]
  },
  "type" : "collection",
  "entry" : [
    {
      "fullUrl" : "urn:uuid:bf6b038b-1334-3dd4-a552-65c169e2265a",
      "resource" : {
        "resourceType" : "PlanDefinition",
        "id" : "manufacturingProcess-unlinked",
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_manufacturingProcess-unlinked\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"manufacturingProcess-unlinked\"> </a><a name=\"hcmanufacturingProcess-unlinked\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition &quot;manufacturingProcess-unlinked&quot; </p></div><p><b>Extension - Plan Document Reference PQ</b>: See on this page: DocumentReference/74d4c070-6596-8252-8ad9-afa515a41feb</p><p><b>Extension - History of Process PQ</b>: This can be text about the history</p><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a</code></p><p><b>type</b>: Manufacturing Process <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#manufacturing-process)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: SubstanceDefinition/c458791f-7cb8-428e-83f7-8a205f821152</p><p><b>description</b>: Narrative description of substance manufacturing process</p><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-pH</blockquote><p><b>category</b>: Physical Property <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-test-category.html\">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - pH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>priority</b>: Critical <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-goalPriority-pq-example.html\">Goal Priority - example</a>#critical)</span></p><h3>Targets</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Long description of the acceptance criteria - pH must be in range 6.9 to 7.1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH &quot;pH&quot;)</span></td><td>6.9-7.1 pH</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-temp</blockquote><p><b>category</b>: Physical Property <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-test-category.html\">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - Temperature <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>priority</b>: Non-critical <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-goalPriority-pq-example.html\">Goal Priority - example</a>#non-critical)</span></p><h3>Targets</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Long description of the control value - Temperature must be below 150°C <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#TEMP &quot;Temperature&quot;)</span></td><td>?-150</td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>code</b>: overall process <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#overall process &quot;Overall Process&quot;)</span></p><blockquote><p><b>action</b></p><p><b>Extension - Process Step Scale PQ</b>: Production Scale (Details: http://terminology.hl7.org/CodeSystem/manufacturing-step-scale code PROD = 'Production Scale', stated as 'Production Scale')</p><blockquote><p><b>Extension - Process Parameters PQ</b></p><blockquote><p><b>url</b></p><code>parameter</code></blockquote><p><b>value</b>: Mix speed <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-process-parameter.html\">Process Parameter Codes</a>#SPEED)</span></p><blockquote><p><b>url</b></p><code>value</code></blockquote><p><b>value</b>: 1500 rpm</p></blockquote><p><b>prefix</b>: 1</p><p><b>description</b>: Description of this step</p><p><b>code</b>: Particle Size Reduction <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#particleSizeReduction)</span></p><blockquote><p><b>documentation</b></p></blockquote><p><b>goalId</b>: goal-control-pH, goal-control-temp</p><blockquote><p><b>participant</b></p></blockquote><blockquote><p><b>participant</b></p></blockquote><blockquote><p><b>participant</b></p></blockquote><blockquote><p><b>participant</b></p></blockquote></blockquote></blockquote></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-plan-document-reference-pq",
            "valueReference" : {
              "reference" : "DocumentReference/74d4c070-6596-8252-8ad9-afa515a41feb"
            }
          },
          //  Process flow diagram 
          //  or could be a Binary 
          // DocumentReference/DocumentReference-process-flow-diagram-dxpq-ex1
          {
            "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-history-of-process-pq",
            "valueMarkdown" : "This can be text about the history"
          }
        ],
        "url" : "http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a",
        "type" : // http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a
        {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
              "code" : "manufacturing-process",
              "display" : "Manufacturing Process"
            }
          ]
        },
        "status" : "active",
        "subjectReference" : {
          "reference" : "SubstanceDefinition/c458791f-7cb8-428e-83f7-8a205f821152"
        },
        "description" : "Narrative description of substance manufacturing process",
        "goal" : [
          // SubstanceDefinition/substance1
          {
            "id" : "goal-control-pH",
            "category" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category",
                  "code" : "C123456",
                  "display" : "Physical Property"
                }
              ]
            },
            "description" : //  this is mandatory, even though we don't really want it 
            {
              "text" : "Controls - pH"
            },
            "priority" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example",
                  "code" : "critical",
                  "display" : "Critical"
                }
              ]
            },
            "target" : [
              {
                "measure" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "pH",
                      "display" : "pH"
                    }
                  ],
                  "text" : "Long description of the acceptance criteria - pH must be in range 6.9 to 7.1"
                },
                "detailRange" : // detailString value="can also be a string"
                {
                  "low" : {
                    "value" : 6.9,
                    "unit" : "pH"
                  },
                  "high" : {
                    "value" : 7.1,
                    "unit" : "pH"
                  }
                }
              }
            ]
          },
          {
            "id" : "goal-control-temp",
            "category" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category",
                  "code" : "C123456",
                  "display" : "Physical Property"
                }
              ]
            },
            "description" : //  this is mandatory, even though we don't really want it 
            {
              "text" : "Controls - Temperature"
            },
            "priority" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example",
                  "code" : "non-critical",
                  "display" : "Non-critical"
                }
              ]
            },
            "target" : [
              {
                "measure" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "TEMP",
                      "display" : "Temperature"
                    }
                  ],
                  "text" : "Long description of the control value - Temperature must be below 150°C"
                },
                "detailRange" : // detailString value="can also be a string"
                {
                  "high" : {
                    "value" : 150,
                    "unit" : "°C",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "Cel"
                  }
                }
              }
            ]
          }
        ],
        "action" : [
          //  outer action is the whole thing, if needed 
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                  "code" : "overall process",
                  "display" : "Overall Process"
                }
              ],
              "text" : "overall process"
            },
            "action" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-process-step-scale-pq",
                    "valueCoding" : {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step-scale",
                      "code" : "PROD",
                      "display" : "Production Scale"
                    }
                  },
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-process-parameters-pq",
                    "extension" : [
                      {
                        "url" : "parameter",
                        "valueCodeableConcept" : {
                          "coding" : [
                            {
                              "system" : "http://terminology.hl7.org/CodeSystem/process-parameter",
                              "code" : "SPEED",
                              "display" : "Mix speed"
                            }
                          ]
                        }
                      },
                      {
                        "url" : "value",
                        "valueQuantity" : {
                          "value" : 1500,
                          "unit" : "rpm"
                        }
                      }
                    ]
                  }
                ],
                "prefix" : "1",
                "description" : "Description of this step",
                "code" : // text value="Step 2 in the process - free text is possible"/
                {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "particleSizeReduction",
                      "display" : "Particle Size Reduction"
                    }
                  ]
                },
                "documentation" : [
                  {
                    "type" : "specification-of",
                    "resourceReference" : {
                      "reference" : "DocumentReference/74d4c070-6596-8252-8ad9-afa515a41fef"
                    }
                  }
                ],
                "goalId" : [
                  "goal-control-pH",
                  "goal-control-temp"
                ],
                "participant" : [
                  // DocumentReference/DocumentReference-image
                  {
                    "typeReference" : {
                      "reference" : "DeviceDefinition/82a39a18-91cf-a19d-76c1-a9e8bad9494c"
                    },
                    "role" : //  this is new in R5 and is not in R4B 
                    // DeviceDefinition/impeller
                    {
                      "coding" : [
                        {
                          "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-manufacturing-equipment-class",
                          "code" : "Compression Milling",
                          "display" : "Compression Milling"
                        }
                      ]
                    }
                  },
                  {
                    "typeReference" : //  added to suppress warning caused by the lack of a true reference, due to it being in extension 
                    {
                      "extension" : [
                        {
                          "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-manufacturing-participant-pq",
                          "valueReference" : {
                            "reference" : "SubstanceDefinition/c458791f-7cb8-428e-83f7-8a205f821153"
                          }
                        }
                      ],
                      "display" : "Starting Material"
                    },
                    "role" : // SubstanceDefinition/startingMaterial
                    {
                      "coding" : [
                        {
                          "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-participant-role",
                          "code" : "StartingMaterial",
                          "display" : "Starting Material"
                        }
                      ]
                    }
                  },
                  {
                    "typeReference" : //  added to suppress warning caused by the lack of a true reference, due to it being in extension 
                    {
                      "extension" : [
                        {
                          "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-manufacturing-participant-pq",
                          "valueReference" : {
                            "reference" : "SubstanceDefinition/c458791f-7cb8-428e-83f7-8a205f821155"
                          }
                        }
                      ],
                      "display" : "Processing Material"
                    },
                    "role" : // SubstanceDefinition/processingMaterial
                    {
                      "coding" : [
                        {
                          "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-participant-role",
                          "code" : "ProcessingMaterial",
                          "display" : "Processing Material"
                        }
                      ]
                    }
                  },
                  {
                    "typeReference" : //  added to suppress warning caused by the lack of a true reference, due to it being in extension 
                    {
                      "extension" : [
                        {
                          "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-manufacturing-participant-pq",
                          "valueReference" : {
                            "reference" : "SubstanceDefinition/c458791f-7cb8-428e-83f7-8a205f821154"
                          }
                        }
                      ],
                      "display" : "Resulting Material"
                    },
                    "role" : // SubstanceDefinition/resultingMaterial
                    {
                      "coding" : [
                        {
                          "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-participant-role",
                          "code" : "ResultingMaterial",
                          "display" : "Resulting Material"
                        }
                      ]
                    }
                  }
                ]
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:82a39a18-91cf-a19d-76c1-a9e8bad9494c",
      "resource" : {
        "resourceType" : "DeviceDefinition",
        "id" : "82a39a18-91cf-a19d-76c1-a9e8bad9494c",
        "text" : // impeller
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DeviceDefinition_82a39a18-91cf-a19d-76c1-a9e8bad9494c\"> </a><p><b>Generated Narrative: DeviceDefinition</b><a name=\"82a39a18-91cf-a19d-76c1-a9e8bad9494c\"> </a><a name=\"hc82a39a18-91cf-a19d-76c1-a9e8bad9494c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DeviceDefinition &quot;82a39a18-91cf-a19d-76c1-a9e8bad9494c&quot; </p></div><h3>DeviceNames</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>Rotating Impeller with 1.5mm screen</td><td>registered-name</td></tr></table><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Maximum Speed <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-device-property.html\">Device Property Codes</a>#Maximum Speed)</span></td><td>5000 RPM</td></tr></table></div>"
        },
        "deviceName" : [
          {
            "name" : "Rotating Impeller with 1.5mm screen",
            "type" : "registered-name"
          }
        ],
        "property" : [
          {
            "type" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/device-property",
                  "code" : "Maximum Speed",
                  "display" : "Maximum Speed"
                }
              ]
            },
            "valueQuantity" : {
              "value" : 5000,
              "unit" : "RPM"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:74d4c070-6596-8252-8ad9-afa515a41feb",
      "resource" : {
        "resourceType" : "DocumentReference",
        "id" : "74d4c070-6596-8252-8ad9-afa515a41feb",
        "meta" : // DocumentReference-process-flow-diagram-dxpq-ex1
        {
          "versionId" : "1",
          "lastUpdated" : "2023-01-12T17:57:08.898+00:00",
          "source" : "#n4xHiP0iat7deVDt"
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DocumentReference_74d4c070-6596-8252-8ad9-afa515a41feb\"> </a><p><b>Generated Narrative: DocumentReference</b><a name=\"74d4c070-6596-8252-8ad9-afa515a41feb\"> </a><a name=\"hc74d4c070-6596-8252-8ad9-afa515a41feb\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DocumentReference &quot;74d4c070-6596-8252-8ad9-afa515a41feb&quot; Version &quot;1&quot; Updated &quot;2023-01-12 17:57:08+0000&quot; </p><p style=\"margin-bottom: 0px\">Information Source: #n4xHiP0iat7deVDt!</p></div><p><b>identifier</b>: <code>http://example.org/fhir/identifier/document</code>/FLOW-001</p><p><b>status</b>: current</p><p><b>type</b>: Process Flow Diagram <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-diagram-type.html\">Diagram Type Codes</a>#ProcessFlowDiagram)</span></p><blockquote><p><b>content</b></p><h3>Attachments</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Url</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://example.org/docStore/flow-001\">https://example.org/docStore/flow-001</a></td></tr></table></blockquote></div>"
        },
        "identifier" : [
          {
            "system" : "http://example.org/fhir/identifier/document",
            "value" : "FLOW-001"
          }
        ],
        "status" : "current",
        "type" : {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/diagram-type",
              "code" : "ProcessFlowDiagram",
              "display" : "Process Flow Diagram"
            }
          ]
        },
        "content" : [
          {
            "attachment" : {
              "url" : "https://example.org/docStore/flow-001"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:74d4c070-6596-8252-8ad9-afa515a41fef",
      "resource" : {
        "resourceType" : "DocumentReference",
        "id" : "74d4c070-6596-8252-8ad9-afa515a41fef",
        "text" : // DocumentReference-image
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DocumentReference_74d4c070-6596-8252-8ad9-afa515a41fef\"> </a><p><b>Generated Narrative: DocumentReference</b><a name=\"74d4c070-6596-8252-8ad9-afa515a41fef\"> </a><a name=\"hc74d4c070-6596-8252-8ad9-afa515a41fef\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DocumentReference &quot;74d4c070-6596-8252-8ad9-afa515a41fef&quot; </p></div><p><b>status</b>: current</p><blockquote><p><b>content</b></p><h3>Attachments</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Url</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://www.accumulus.org/wp-content/uploads/2022/05/Accumulus_Logo_horizontal.png\">https://www.accumulus.org/wp-content/uploads/2022/05/Accumulus_Logo_horizontal.png</a></td></tr></table></blockquote></div>"
        },
        "status" : "current",
        "content" : [
          {
            "attachment" : {
              "url" : "https://www.accumulus.org/wp-content/uploads/2022/05/Accumulus_Logo_horizontal.png"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:c458791f-7cb8-428e-83f7-8a205f821152",
      "resource" : {
        "resourceType" : "SubstanceDefinition",
        "id" : "c458791f-7cb8-428e-83f7-8a205f821152",
        "text" : // substance1
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_c458791f-7cb8-428e-83f7-8a205f821152\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"c458791f-7cb8-428e-83f7-8a205f821152\"> </a><a name=\"hcc458791f-7cb8-428e-83f7-8a205f821152\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;c458791f-7cb8-428e-83f7-8a205f821152&quot; </p></div><p><b>manufacturer</b>: See on this page: Organization/9fe98cfa-9245-8313-0fc5-d15e613b5d6d</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table></div>"
        },
        "manufacturer" : [
          {
            "reference" : "Organization/9fe98cfa-9245-8313-0fc5-d15e613b5d6d"
          }
        ],
        "name" : [
          // Organization/substance-manufacturer
          {
            "name" : "Stelbatolol"
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:9fe98cfa-9245-8313-0fc5-d15e613b5d6d",
      "resource" : {
        "resourceType" : "Organization",
        "id" : "9fe98cfa-9245-8313-0fc5-d15e613b5d6d",
        "text" : // substance-manufacturer
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_9fe98cfa-9245-8313-0fc5-d15e613b5d6d\"> </a><p><b>Generated Narrative: Organization</b><a name=\"9fe98cfa-9245-8313-0fc5-d15e613b5d6d\"> </a><a name=\"hc9fe98cfa-9245-8313-0fc5-d15e613b5d6d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;9fe98cfa-9245-8313-0fc5-d15e613b5d6d&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
        },
        "identifier" : [
          {
            "system" : "urn:oid:2.16.840.1.113883.4.82",
            "value" : "3003040516"
          }
        ],
        "active" : true,
        "type" : [
          //  FDA establishment identifier 
          {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                "code" : "drug-substance-manufacture",
                "display" : "Drug Substance Manufacture"
              }
            ]
          }
        ],
        "name" : "AAA Molybdenum Products, Inc.",
        "contact" : [
          {
            "address" : {
              "line" : [
                "7233 W 116th Pl",
                "Ste C"
              ],
              "city" : "Broomfield",
              "state" : "Colorado",
              "postalCode" : "80020",
              "country" : "USA"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:c458791f-7cb8-428e-83f7-8a205f821153",
      "resource" : {
        "resourceType" : "SubstanceDefinition",
        "id" : "c458791f-7cb8-428e-83f7-8a205f821153",
        "text" : // startingMaterial
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_c458791f-7cb8-428e-83f7-8a205f821153\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"c458791f-7cb8-428e-83f7-8a205f821153\"> </a><a name=\"hcc458791f-7cb8-428e-83f7-8a205f821153\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;c458791f-7cb8-428e-83f7-8a205f821153&quot; </p></div><p><b>manufacturer</b>: See on this page: Organization/9fe98cfa-9245-8313-0fc5-d15e613b5d6d</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatosubstance</td></tr></table></div>"
        },
        "manufacturer" : [
          {
            "reference" : "Organization/9fe98cfa-9245-8313-0fc5-d15e613b5d6d"
          }
        ],
        "name" : [
          // Organization/substance-manufacturer
          {
            "name" : "Stelbatosubstance"
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:c458791f-7cb8-428e-83f7-8a205f821154",
      "resource" : {
        "resourceType" : "SubstanceDefinition",
        "id" : "c458791f-7cb8-428e-83f7-8a205f821154",
        "text" : // resultingMaterial
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_c458791f-7cb8-428e-83f7-8a205f821154\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"c458791f-7cb8-428e-83f7-8a205f821154\"> </a><a name=\"hcc458791f-7cb8-428e-83f7-8a205f821154\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;c458791f-7cb8-428e-83f7-8a205f821154&quot; </p></div><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Resultothane</td></tr></table></div>"
        },
        "name" : [
          {
            "name" : "Resultothane"
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:c458791f-7cb8-428e-83f7-8a205f821155",
      "resource" : {
        "resourceType" : "SubstanceDefinition",
        "id" : "c458791f-7cb8-428e-83f7-8a205f821155",
        "text" : // processingMaterial
        {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_c458791f-7cb8-428e-83f7-8a205f821155\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"c458791f-7cb8-428e-83f7-8a205f821155\"> </a><a name=\"hcc458791f-7cb8-428e-83f7-8a205f821155\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;c458791f-7cb8-428e-83f7-8a205f821155&quot; </p></div><p><b>manufacturer</b>: See on this page: Organization/9fe98cfa-9245-8313-0fc5-d15e613b5d6d</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Processohol</td></tr></table></div>"
        },
        "manufacturer" : [
          {
            "reference" : "Organization/9fe98cfa-9245-8313-0fc5-d15e613b5d6d"
          }
        ],
        "name" : [
          // Organization/substance-manufacturer
          {
            "name" : "Processohol"
          }
        ]
      }
    }
  ]
}