Pharmaceutical Quality (Industry)
1.0.0 - STU1 International flag

Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions

Example Bundle: Example: Bundle – Substance General Properties

Bundle bundle-drug-substance-general-properties-pq-ex1 of type collection

Entry 1 - fullUrl = urn:uuid:57a9af63-315d-1585-a261-0e337b289390

Resource SubstanceDefinition:

Generated Narrative: SubstanceDefinition

Resource SubstanceDefinition "substancedefinition-substance-drug-pq-ex1"

property

type: Appearance (Substance Property - example#appearance)

value: white to slightly yellow powder ()

property

type: Solubility purified water (PhEur) (Substance Property - example#solubility-water-pheur)

value: freely soluble (Substance Property Value - example#sol-free "Freely soluble")

property

Extension - Substance Property Range PQ: 23-27 mg/mL

type: Solubility purified water (PhEur) (Substance Property - example#solubility-water-pheur)

property

type: Solubility Acetone (PhEur) (Substance Property - example#solubility-acetone-pheur)

value: slightly soluble (Substance Property Value - example#sol-slight "Slightly soluble")

property

Extension - Substance Property Range PQ: 2-3 mg/mL

type: Solubility acetone (PhEur) (Substance Property - example#solubility-acetone-pheur)

property

type: Solubility Ethanol (PhEur) (Substance Property - example#solubility-ethanol-pheur)

value: soluble (Substance Property Value - example#sol-soluble "Soluble")

property

Extension - Substance Property Range PQ: 15-17 mg/mL

type: Solubility ethanol (PhEur) (Substance Property - example#solubility-ethanol-pheur)

property

type: Solubility at saturation in Purifed Water after 2 hours (approx) (Substance Property - example#solubility-aq-water-2h-approx)

value: 21 mg/mL

property

type: Glucose solution (5%) (Substance Property - example#solubility-aq-glucose-2h-approx "Solubility at saturation in Glucose (5%) after 2 hours (approx)")

value: 2.5 mg/mL

property

Extension - Substance Property Parameter PQ

url

parameter

value: pH (Details: http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example code pH = 'pH', stated as 'pH')

url

value

value: 1.2

type: Solubility as a function of pH in USP buffers (Substance Property - example#solubility-usp-ph)

value: 22 mg/mL

property

Extension - Substance Property Parameter PQ

url

parameter

value: pH (Details: http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example code pH = 'pH', stated as 'pH')

url

value

value: 4.5

type: Solubility as a function of pH in USP buffers (Substance Property - example#solubility-usp-ph)

value: 29 mg/mL

property

Extension - Substance Property Range PQ: 6.7-6.8

Extension - Substance Property Parameter PQ

url

parameter

value: Concentration (Details: http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example code concentration = 'Concentration', stated as 'Concentration')

url

value

value: 10 mg/ml

Extension - Substance Property Parameter PQ

url

parameter

value: Temperature (Details: http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example code temperature = 'Temperature', stated as 'Temperature')

url

value

value: 25 °C

type: pH in aqueous solution (Substance Property - example#ph-aq)

property

type: Hygroscopy (Substance Property - example#hygroscopy)

value: Hygroscopic (Substance Property - example#hygroscopy-hygroscopic)

Structures

-Stereochemistry
*One asymmetric center and one axis of chirality; (S,M) - enantiomer ()

Names

-Name
*Stelbatolol