Pharmaceutical Quality (Industry)
1.0.0 - STU1
Pharmaceutical Quality (Industry)
1.0.0 - STU1
Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions
// Product Batch Analysys
{
"resourceType" : "Bundle",
"id" : "bundle-batch-analysis-pq-ex1-prod",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-batch-analysis-pq"
]
},
"type" : "collection",
"entry" : [
{
"fullUrl" : "urn:uuid:2038e4c7-22b8-4c56-2d28-6c077648763f",
"resource" : {
"resourceType" : "PlanDefinition",
"id" : "2038e4c7-22b8-4c56-2d28-6c077648763f",
"meta" : // specificationProtocol
{
"profile" : [
🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PlanDefinition-drug-pq"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_2038e4c7-22b8-4c56-2d28-6c077648763f\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"2038e4c7-22b8-4c56-2d28-6c077648763f\"> </a><a name=\"hc2038e4c7-22b8-4c56-2d28-6c077648763f\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition "2038e4c7-22b8-4c56-2d28-6c077648763f" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-PlanDefinition-drug-pq.html\">PlanDefinition - Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</code></p><p><b>title</b>: P.5.4 BATCH ANALYSIS</p><p><b>type</b>: Specification Protocol <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#1244577)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>description</b>: Narrative description of analysis</p><blockquote><p><b>action</b></p><p><b>title</b>: Batch Specification for Drug Product</p><p><b>code</b>: Overall set of actions <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>action</b></p><p><b>title</b>: Release</p><p><b>code</b>: Timing Group <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>timing</b>: Code: Release time</p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: End of shelf life</p><p><b>code</b>: Timing Group <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>timing</b>: Code: At end of shelf life</p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote></div>"
},
"url" : "http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f",
"title" : "P.5.4 BATCH ANALYSIS",
"type" : // http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f
// Added (8/22/2023)
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
"code" : "1244577",
"display" : "Specification Protocol"
}
]
},
"status" : "active",
"subjectReference" : {
"reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
},
"description" : "Narrative description of analysis",
"action" : [
// MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
{
"title" : "Batch Specification for Drug Product",
"code" : {
"text" : "Overall set of actions"
},
"action" : [
{
"title" : "Release",
"code" : {
"text" : "Timing Group"
},
"timingTiming" : {
"code" : {
"text" : "Release time"
}
},
"action" : [
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-91c2-2d06-47cb5b295e72"
},
// ObservationDefinition/Description
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"
},
// ObservationDefinition/Identification
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/39ffd548-bb3d-43b9-9ca9-83f26631712b"
},
// ObservationDefinition/Assay
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
// ObservationDefinition/Degradation
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/8f5d8abf-2cf4-8617-1e41-a74d90210dcc"
},
// ObservationDefinition/Dissolution
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/33a9d578-6e6b-7606-72bc-6775d36c1930"
},
// ObservationDefinition/DissolutionQ80
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a4a4-9168-2602140548d7"
},
// ObservationDefinition/Uniformity
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/d999ee06-6595-762c-1bda-0818ab1c6c0e"
},
// ObservationDefinition/Microbiological
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"
}
]
},
// ObservationDefinition/Water
{
"title" : "End of shelf life",
"code" : {
"text" : "Timing Group"
},
"timingTiming" : {
"code" : {
"text" : "At end of shelf life"
}
},
"action" : [
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/220059d8-5aed-6d9e-563f-aac39b315c05"
},
// ObservationDefinition/DescriptionEnd
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/7c01a2fc-7ced-92b5-3ce7-8279d9df2421"
},
// ObservationDefinition/IdentificationEnd
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/9d1fd19a-9265-7b02-865e-75c12e952ad4"
},
// ObservationDefinition/AssayEnd
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/d5d084d0-37c9-3e1e-1d3f-97e7798540a9"
},
// ObservationDefinition/DegradationEnd
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/062bf235-44e2-55c4-9213-bbe5e12d5620"
},
// ObservationDefinition/DissolutionEnd
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/2b01c026-1687-24c7-4c8c-e5d98ada8683"
},
// ObservationDefinition/UniformityEnd
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/60529d20-a55e-2575-4cb7-9f207ef8a2a1"
},
// ObservationDefinition/MicrobiologicalEnd
{
"code" : {
"text" : "Test"
},
"definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/7d0b63fc-5194-33d0-3e4a-0aef5edf7ba6"
}
]
}
]
}
]
}
},
// ObservationDefinition/WaterEnd
{
"fullUrl" : "urn:uuid:fc07b5d5-9fe1-91c2-2d06-47cb5b295e72",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "fc07b5d5-9fe1-91c2-2d06-47cb5b295e72",
"text" : // Description
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc07b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc07b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a><a name=\"hcfc07b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "fc07b5d5-9fe1-91c2-2d06-47cb5b295e72" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: Description</p><p><b>status</b>: active</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>method</b>: Visual inspection <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-91c2-2d06-47cb5b295e72",
"title" : "Description",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-91c2-2d06-47cb5b295e72
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DESC",
"display" : "Description"
}
],
"text" : "Description"
},
"method" : {
"text" : "Visual inspection"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "An orange film-coated tablet, debossed with 175 on one side"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:220059d8-5aed-6d9e-563f-aac39b315c05",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "220059d8-5aed-6d9e-563f-aac39b315c05",
"text" : // DescriptionEnd
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_220059d8-5aed-6d9e-563f-aac39b315c05\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"220059d8-5aed-6d9e-563f-aac39b315c05\"> </a><a name=\"hc220059d8-5aed-6d9e-563f-aac39b315c05\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "220059d8-5aed-6d9e-563f-aac39b315c05" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/220059d8-5aed-6d9e-563f-aac39b315c05</code></p><p><b>title</b>: Description</p><p><b>status</b>: active</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/220059d8-5aed-6d9e-563f-aac39b315c05",
"title" : "Description",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/220059d8-5aed-6d9e-563f-aac39b315c05
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DESC",
"display" : "Description"
}
],
"text" : "Description"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "As for release"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:3b0e878e-4bc9-8864-862f-e28b21233e8d",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "3b0e878e-4bc9-8864-862f-e28b21233e8d",
"text" : // Identification
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_3b0e878e-4bc9-8864-862f-e28b21233e8d\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"3b0e878e-4bc9-8864-862f-e28b21233e8d\"> </a><a name=\"hc3b0e878e-4bc9-8864-862f-e28b21233e8d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "3b0e878e-4bc9-8864-862f-e28b21233e8d" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</code></p><p><b>title</b>: Identification</p><p><b>status</b>: active</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>method</b>: ID by UHPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d",
"title" : "Identification",
"status" : "active",
"code" : // <meta>
<profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"/>
</meta>
// http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IDT",
"display" : "Identification"
}
],
"text" : "Identification"
},
"method" : {
"text" : "ID by UHPLC"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "Consistent with the retention time and UV spectrum of the reference standard"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:7c01a2fc-7ced-92b5-3ce7-8279d9df2421",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "7c01a2fc-7ced-92b5-3ce7-8279d9df2421",
"text" : // IdentificationEnd
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_7c01a2fc-7ced-92b5-3ce7-8279d9df2421\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"7c01a2fc-7ced-92b5-3ce7-8279d9df2421\"> </a><a name=\"hc7c01a2fc-7ced-92b5-3ce7-8279d9df2421\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "7c01a2fc-7ced-92b5-3ce7-8279d9df2421" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/7c01a2fc-7ced-92b5-3ce7-8279d9df2421</code></p><p><b>title</b>: Identification</p><p><b>status</b>: active</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/7c01a2fc-7ced-92b5-3ce7-8279d9df2421",
"title" : "Identification",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/7c01a2fc-7ced-92b5-3ce7-8279d9df2421
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IDT",
"display" : "Identification"
}
],
"text" : "Identification"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "As for release"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:39ffd548-bb3d-43b9-9ca9-83f26631712b",
"resource" : // fullUrl value="http://hl7.org/fhir/uv/pharm-quality/ObservationDefinition/Assay"/
{
"resourceType" : "ObservationDefinition",
"id" : "39ffd548-bb3d-43b9-9ca9-83f26631712b",
"text" : // Assay
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_39ffd548-bb3d-43b9-9ca9-83f26631712b\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"39ffd548-bb3d-43b9-9ca9-83f26631712b\"> </a><a name=\"hc39ffd548-bb3d-43b9-9ca9-83f26631712b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "39ffd548-bb3d-43b9-9ca9-83f26631712b" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/39ffd548-bb3d-43b9-9ca9-83f26631712b</code></p><p><b>title</b>: Assay</p><p><b>status</b>: active</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>method</b>: Assay by UHPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/39ffd548-bb3d-43b9-9ca9-83f26631712b",
"title" : "Assay",
"status" : "active",
"code" : // <meta>
<profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"/>
</meta>
// http://hl7.org/fhir/uv/pharm-quality/ObservationDefinition/Assay
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "ASSAY",
"display" : "Assay"
}
],
"text" : "Assay"
},
"method" : {
"text" : "Assay by UHPLC"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "95% to 105% of label claim"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:9d1fd19a-9265-7b02-865e-75c12e952ad4",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "9d1fd19a-9265-7b02-865e-75c12e952ad4",
"text" : // AssayEnd
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_9d1fd19a-9265-7b02-865e-75c12e952ad4\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"9d1fd19a-9265-7b02-865e-75c12e952ad4\"> </a><a name=\"hc9d1fd19a-9265-7b02-865e-75c12e952ad4\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "9d1fd19a-9265-7b02-865e-75c12e952ad4" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/9d1fd19a-9265-7b02-865e-75c12e952ad4</code></p><p><b>title</b>: Assay</p><p><b>status</b>: active</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/9d1fd19a-9265-7b02-865e-75c12e952ad4",
"title" : "Assay",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/9d1fd19a-9265-7b02-865e-75c12e952ad4
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "ASSAY",
"display" : "Assay"
}
],
"text" : "Assay"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "As for release"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:8bdea820-4197-7c7d-0990-7be06bf78aaf",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "8bdea820-4197-7c7d-0990-7be06bf78aaf",
"text" : // Degradation
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_8bdea820-4197-7c7d-0990-7be06bf78aaf\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"8bdea820-4197-7c7d-0990-7be06bf78aaf\"> </a><a name=\"hc8bdea820-4197-7c7d-0990-7be06bf78aaf\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "8bdea820-4197-7c7d-0990-7be06bf78aaf" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</code></p><p><b>title</b>: Degradation Products</p><p><b>status</b>: active</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>method</b>: Degradation products by UHPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.2</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.3</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.3</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Individual unspecified degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.2</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Total degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-1.4</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf",
"title" : "Degradation Products",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
]
},
"method" : {
"text" : "Degradation products by UHPLC"
},
"qualifiedValue" : [
{
"appliesTo" : [
{
"text" : "Impurity 1"
}
],
"range" : // could be a code
{
"high" : {
"value" : 0.2,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"appliesTo" : [
{
"text" : "Impurity 2"
}
],
"range" : {
"high" : {
"value" : 0.3,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"appliesTo" : [
{
"text" : "Impurity 3"
}
],
"range" : {
"high" : {
"value" : 0.3,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"appliesTo" : [
{
"text" : "Individual unspecified degradation products"
}
],
"range" : {
"high" : {
"value" : 0.2,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"appliesTo" : [
{
"text" : "Total degradation products"
}
],
"range" : {
"high" : {
"value" : 1.4,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
}
],
"component" : [
{
"code" : // are expected to have a component that says what impurity this one is
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
}
}
]
}
},
{
"fullUrl" : "urn:uuid:d5d084d0-37c9-3e1e-1d3f-97e7798540a9",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "d5d084d0-37c9-3e1e-1d3f-97e7798540a9",
"text" : // DegradationEnd
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_d5d084d0-37c9-3e1e-1d3f-97e7798540a9\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"d5d084d0-37c9-3e1e-1d3f-97e7798540a9\"> </a><a name=\"hcd5d084d0-37c9-3e1e-1d3f-97e7798540a9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "d5d084d0-37c9-3e1e-1d3f-97e7798540a9" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/d5d084d0-37c9-3e1e-1d3f-97e7798540a9</code></p><p><b>title</b>: Degradation Products</p><p><b>status</b>: active</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.8</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.4</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.4</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Individual unspecified degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-2.3</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Total degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-2.3</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/d5d084d0-37c9-3e1e-1d3f-97e7798540a9",
"title" : "Degradation Products",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/d5d084d0-37c9-3e1e-1d3f-97e7798540a9
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
]
},
"qualifiedValue" : [
{
"appliesTo" : [
{
"text" : "Impurity 1"
}
],
"range" : // could be a code
{
"high" : {
"value" : 0.8,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"appliesTo" : [
{
"text" : "Impurity 2"
}
],
"range" : {
"high" : {
"value" : 0.4,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"appliesTo" : [
{
"text" : "Impurity 3"
}
],
"range" : {
"high" : {
"value" : 0.4,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"appliesTo" : [
{
"text" : "Individual unspecified degradation products"
}
],
"range" : {
"high" : {
"value" : 2.3,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"appliesTo" : [
{
"text" : "Total degradation products"
}
],
"range" : {
"high" : {
"value" : 2.3,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
}
],
"component" : [
{
"code" : // are expected to have a component that says what impurity this one is
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
}
}
]
}
},
{
"fullUrl" : "urn:uuid:8f5d8abf-2cf4-8617-1e41-a74d90210dcc",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "8f5d8abf-2cf4-8617-1e41-a74d90210dcc",
"text" : // Dissolution
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_8f5d8abf-2cf4-8617-1e41-a74d90210dcc\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"8f5d8abf-2cf4-8617-1e41-a74d90210dcc\"> </a><a name=\"hc8f5d8abf-2cf4-8617-1e41-a74d90210dcc\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "8f5d8abf-2cf4-8617-1e41-a74d90210dcc" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/8f5d8abf-2cf4-8617-1e41-a74d90210dcc</code></p><p><b>title</b>: Dissolution</p><p><b>status</b>: active</p><p><b>code</b>: Dissolution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Dissolution)</span></p><p><b>method</b>: Apparatus 2 (paddles), UV measurement <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/8f5d8abf-2cf4-8617-1e41-a74d90210dcc",
"title" : "Dissolution",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/8f5d8abf-2cf4-8617-1e41-a74d90210dcc
{
"coding" : [
// possibly "G1113"
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Dissolution",
"display" : "Dissolution"
}
],
"text" : "Dissolution"
},
"method" : {
"text" : "Apparatus 2 (paddles), UV measurement"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "Shall comply with the requirements of the harmonised USP/JP/Ph"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:33a9d578-6e6b-7606-72bc-6775d36c1930",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "33a9d578-6e6b-7606-72bc-6775d36c1930",
"text" : // DissolutionQ80
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_33a9d578-6e6b-7606-72bc-6775d36c1930\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"33a9d578-6e6b-7606-72bc-6775d36c1930\"> </a><a name=\"hc33a9d578-6e6b-7606-72bc-6775d36c1930\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "33a9d578-6e6b-7606-72bc-6775d36c1930" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/33a9d578-6e6b-7606-72bc-6775d36c1930</code></p><p><b>title</b>: Dissolution (Q)</p><p><b>status</b>: active</p><p><b>code</b>: Dissolution Quantity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Dissolution Quantity)</span></p><p><b>method</b>: Apparatus 2 (paddles), UV measurement <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Condition</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>at 30 minutes</td><td>80-? %</td></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/33a9d578-6e6b-7606-72bc-6775d36c1930",
"title" : "Dissolution (Q)",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/33a9d578-6e6b-7606-72bc-6775d36c1930
// text value="Dissolution (Q)"/
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Dissolution Quantity",
"display" : "Dissolution Quantity"
}
]
},
"method" : {
"text" : "Apparatus 2 (paddles), UV measurement"
},
"qualifiedValue" : [
{
"condition" : "at 30 minutes",
"range" : {
"low" : {
"value" : 80,
"unit" : "%"
}
}
}
]
}
},
{
"fullUrl" : "urn:uuid:062bf235-44e2-55c4-9213-bbe5e12d5620",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "062bf235-44e2-55c4-9213-bbe5e12d5620",
"text" : // DissolutionEnd
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a><a name=\"hc062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "062bf235-44e2-55c4-9213-bbe5e12d5620" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/062bf235-44e2-55c4-9213-bbe5e12d5620</code></p><p><b>title</b>: Dissolution</p><p><b>status</b>: active</p><p><b>code</b>: Dissolution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Dissolution)</span></p><p><b>method</b>: Apparatus 2 (paddles), UV measurement <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/062bf235-44e2-55c4-9213-bbe5e12d5620",
"title" : "Dissolution",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/062bf235-44e2-55c4-9213-bbe5e12d5620
// text value="Dissolution"/
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Dissolution",
"display" : "Dissolution"
}
]
},
"method" : {
"text" : "Apparatus 2 (paddles), UV measurement"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "As for release"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:31e29d22-5fcb-546e-24fd-52a4a4004467",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "31e29d22-5fcb-546e-24fd-52a4a4004467",
"text" : // Water
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_31e29d22-5fcb-546e-24fd-52a4a4004467\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"31e29d22-5fcb-546e-24fd-52a4a4004467\"> </a><a name=\"hc31e29d22-5fcb-546e-24fd-52a4a4004467\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "31e29d22-5fcb-546e-24fd-52a4a4004467" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>method</b>: USP <921> <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-1.0</td></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467",
"title" : "Water Content",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "WaterContent",
"display" : "Water Content"
}
],
"text" : "Water Content"
},
"method" : {
"text" : "USP <921>"
},
"qualifiedValue" : [
{
"range" : {
"high" : {
"value" : 1.0,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
}
]
}
},
{
"fullUrl" : "urn:uuid:7d0b63fc-5194-33d0-3e4a-0aef5edf7ba6",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "7d0b63fc-5194-33d0-3e4a-0aef5edf7ba6",
"text" : // WaterEnd
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_7d0b63fc-5194-33d0-3e4a-0aef5edf7ba6\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"7d0b63fc-5194-33d0-3e4a-0aef5edf7ba6\"> </a><a name=\"hc7d0b63fc-5194-33d0-3e4a-0aef5edf7ba6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "7d0b63fc-5194-33d0-3e4a-0aef5edf7ba6" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/7d0b63fc-5194-33d0-3e4a-0aef5edf7ba6</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>method</b>: USP <921> <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-2.0</td></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/7d0b63fc-5194-33d0-3e4a-0aef5edf7ba6",
"title" : "Water Content",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/7d0b63fc-5194-33d0-3e4a-0aef5edf7ba6
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "WaterContent",
"display" : "Water Content"
}
],
"text" : "Water Content"
},
"method" : {
"text" : "USP <921>"
},
"qualifiedValue" : [
{
"range" : {
"high" : {
"value" : 2.0,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
}
]
}
},
{
"fullUrl" : "urn:uuid:d999ee06-6595-762c-1bda-0818ab1c6c0e",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "d999ee06-6595-762c-1bda-0818ab1c6c0e",
"text" : // Microbiological
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_d999ee06-6595-762c-1bda-0818ab1c6c0e\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"d999ee06-6595-762c-1bda-0818ab1c6c0e\"> </a><a name=\"hcd999ee06-6595-762c-1bda-0818ab1c6c0e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "d999ee06-6595-762c-1bda-0818ab1c6c0e" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/d999ee06-6595-762c-1bda-0818ab1c6c0e</code></p><p><b>title</b>: Microbiological</p><p><b>status</b>: active</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>method</b>: Ph Eur <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/d999ee06-6595-762c-1bda-0818ab1c6c0e",
"title" : "Microbiological",
"status" : "active",
"code" : // <meta>
<profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"/>
</meta>
// http://example-server.com/fhir/ObservationDefinition/d999ee06-6595-762c-1bda-0818ab1c6c0e
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Microbiological Quality",
"display" : "Microbiological Quality"
}
],
"text" : "Microbiological Quality"
},
"method" : {
"text" : "Ph Eur"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "Shall comply with the requirements of the Ph Eur"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:60529d20-a55e-2575-4cb7-9f207ef8a2a1",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "60529d20-a55e-2575-4cb7-9f207ef8a2a1",
"text" : // MicrobiologicalEnd
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_60529d20-a55e-2575-4cb7-9f207ef8a2a1\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"60529d20-a55e-2575-4cb7-9f207ef8a2a1\"> </a><a name=\"hc60529d20-a55e-2575-4cb7-9f207ef8a2a1\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "60529d20-a55e-2575-4cb7-9f207ef8a2a1" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/60529d20-a55e-2575-4cb7-9f207ef8a2a1</code></p><p><b>title</b>: Microbiological</p><p><b>status</b>: active</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>method</b>: Ph Eur <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/60529d20-a55e-2575-4cb7-9f207ef8a2a1",
"title" : "Microbiological",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/60529d20-a55e-2575-4cb7-9f207ef8a2a1
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Microbiological Quality",
"display" : "Microbiological Quality"
}
],
"text" : "Microbiological Quality"
},
"method" : {
"text" : "Ph Eur"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "As for release"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:ef17cff1-6586-a4a4-9168-2602140548d7",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "ef17cff1-6586-a4a4-9168-2602140548d7",
"text" : // Uniformity
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_ef17cff1-6586-a4a4-9168-2602140548d7\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"ef17cff1-6586-a4a4-9168-2602140548d7\"> </a><a name=\"hcef17cff1-6586-a4a4-9168-2602140548d7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "ef17cff1-6586-a4a4-9168-2602140548d7" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a4a4-9168-2602140548d7</code></p><p><b>title</b>: Uniformity of dosage</p><p><b>status</b>: active</p><p><b>code</b>: uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>method</b>: Weight variation <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a4a4-9168-2602140548d7",
"title" : "Uniformity of dosage",
"status" : "active",
"code" : // <meta>
<profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"/>
</meta>
// http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a4a4-9168-2602140548d7
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "uniformity-dosage",
"display" : "uniformity of dosage units (by weight)"
}
],
"text" : "uniformity of dosage units (by weight)"
},
"method" : {
"text" : "Weight variation"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "Shall comply with the requirements of the harmonised USP/JP/Ph Eur"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:2b01c026-1687-24c7-4c8c-e5d98ada8683",
"resource" : {
"resourceType" : "ObservationDefinition",
"id" : "2b01c026-1687-24c7-4c8c-e5d98ada8683",
"text" : // UniformityEnd
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_2b01c026-1687-24c7-4c8c-e5d98ada8683\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"2b01c026-1687-24c7-4c8c-e5d98ada8683\"> </a><a name=\"hc2b01c026-1687-24c7-4c8c-e5d98ada8683\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition "2b01c026-1687-24c7-4c8c-e5d98ada8683" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/2b01c026-1687-24c7-4c8c-e5d98ada8683</code></p><p><b>title</b>: Uniformity of dosage</p><p><b>status</b>: active</p><p><b>code</b>: uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
},
"url" : "http://example-server.com/fhir/ObservationDefinition/2b01c026-1687-24c7-4c8c-e5d98ada8683",
"title" : "Uniformity of dosage",
"status" : "active",
"code" : // http://example-server.com/fhir/ObservationDefinition/2b01c026-1687-24c7-4c8c-e5d98ada8683
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "uniformity-dosage",
"display" : "uniformity of dosage units (by weight)"
}
],
"text" : "uniformity of dosage units (by weight)"
},
"qualifiedValue" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
"valueString" : "As for release"
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51",
"resource" : {
"resourceType" : "Medication",
"id" : "339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51",
"text" : // medication-actual-batch
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\"> </a><p><b>Generated Narrative: Medication</b><a name=\"339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\"> </a><a name=\"hc339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication "339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51" </p></div><p><b>code</b>: <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , </td><td>33445</td></tr></table></div>"
},
"code" : {
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
"valueReference" : {
"reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
}
}
]
},
"batch" : // todo consider change this be the MID?
// MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
{
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
"extension" : [
{
"url" : "manufacturingDate",
"valueDateTime" : "2020-06"
},
{
"url" : "batchQuantity",
"valueQuantity" : {
"value" : 100100,
"unit" : "tablets"
}
},
{
"url" : "batchUtilization",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C185328",
"display" : "Stability Study"
}
],
"text" : "PPQ / Stability"
}
},
{
"url" : "assignedManufacturer",
"valueReference" : {
"reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
}
},
// Organization/manufacturer
{
"url" : "container",
"extension" : [
{
"url" : "closureSystemDescription",
"valueString" : "100 cc HDPE Bottle 2 g desiccant"
}
]
}
]
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
"valueDateTime" : "2020-08"
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
"valueDateTime" : "2019-09-08"
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-manufacturing-process-pq",
"valueReference" : {
"reference" : "PlanDefinition/246e9583-6253-6cc7-9c12-3b624f3308c1"
}
},
// PlanDefinition/plandefinition-drug-pq-ex4-mnf-process
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
"valueQuantity" : {
"value" : 4.8,
"unit" : "kg"
}
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
"valueReference" : {
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
}
}
],
"lotNumber" : "33445"
}
}
},
// Organization/packaging
// local extensions
{
"fullUrl" : "urn:uuid:a9dfda53-734b-045f-7ae4-94a6281d53bc",
"resource" : {
"resourceType" : "Medication",
"id" : "a9dfda53-734b-045f-7ae4-94a6281d53bc",
"text" : // medication-actual-batch-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\"> </a><p><b>Generated Narrative: Medication</b><a name=\"a9dfda53-734b-045f-7ae4-94a6281d53bc\"> </a><a name=\"hca9dfda53-734b-045f-7ae4-94a6281d53bc\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication "a9dfda53-734b-045f-7ae4-94a6281d53bc" </p></div><p><b>code</b>: <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , </td><td>33446</td></tr></table></div>"
},
"code" : {
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
"valueReference" : {
"reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
}
}
]
},
"batch" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
{
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
"extension" : [
{
"url" : "manufacturingDate",
"valueDateTime" : "2020-06"
},
{
"url" : "batchQuantity",
"valueQuantity" : {
"value" : 100050,
"unit" : "tablets"
}
},
{
"url" : "batchUtilization",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C185328",
"display" : "Stability Study"
}
],
"text" : "PPQ / Stability"
}
},
{
"url" : "assignedManufacturer",
"valueReference" : {
"reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
}
},
// Organization/manufacturer
{
"url" : "container",
"extension" : [
{
"url" : "closureSystemDescription",
"valueString" : "100 cc HDPE Bottle 2 g desiccant"
}
]
}
]
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
"valueDateTime" : "2019-09-08"
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-manufacturing-process-pq",
"valueReference" : {
"reference" : "PlanDefinition/246e9583-6253-6cc7-9c12-3b624f3308c1"
}
},
// PlanDefinition/plandefinition-drug-pq-ex4-mnf-process
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
"valueDateTime" : "2020-08"
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
"valueReference" : {
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
}
},
// Organization/packaging
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
"valueQuantity" : {
"value" : 4.8,
"unit" : "kg"
}
}
],
"lotNumber" : "33446"
}
}
},
// local extensions
{
"fullUrl" : "urn:uuid:c6f5fadd-62e6-3a01-93d9-b3b182f67d06",
"resource" : {
"resourceType" : "Medication",
"id" : "c6f5fadd-62e6-3a01-93d9-b3b182f67d06",
"text" : // medication-actual-batch-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\"> </a><p><b>Generated Narrative: Medication</b><a name=\"c6f5fadd-62e6-3a01-93d9-b3b182f67d06\"> </a><a name=\"hcc6f5fadd-62e6-3a01-93d9-b3b182f67d06\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication "c6f5fadd-62e6-3a01-93d9-b3b182f67d06" </p></div><p><b>code</b>: <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , </td><td>33447</td></tr></table></div>"
},
"code" : {
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
"valueReference" : {
"reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
}
}
]
},
"batch" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
{
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
"extension" : [
{
"url" : "manufacturingDate",
"valueDateTime" : "2020-06"
},
{
"url" : "batchQuantity",
"valueQuantity" : {
"value" : 100125,
"unit" : "tablets"
}
},
{
"url" : "batchUtilization",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
"code" : "C185328",
"display" : "Stability Study"
}
],
"text" : "PPQ / Stability"
}
},
{
"url" : "assignedManufacturer",
"valueReference" : {
"reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
}
},
// Organization/manufacturer
{
"url" : "container",
"extension" : [
{
"url" : "closureSystemDescription",
"valueString" : "100 cc HDPE Bottle 2 g desiccant"
}
]
}
]
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
"valueDateTime" : "2019-09-08"
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-manufacturing-process-pq",
"valueReference" : {
"reference" : "PlanDefinition/246e9583-6253-6cc7-9c12-3b624f3308c1"
}
},
// PlanDefinition/plandefinition-drug-pq-ex4-mnf-process
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
"valueQuantity" : {
"value" : 4.8,
"unit" : "kg"
}
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
"valueDateTime" : "2020-08"
},
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
"valueReference" : {
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
}
}
],
"lotNumber" : "33447"
}
}
},
// Organization/packaging
// local extensions
{
"fullUrl" : "urn:uuid:0102bca4-46c1-a6bf-1025-cd403fee710a",
"resource" : {
"resourceType" : "Organization",
"id" : "0102bca4-46c1-a6bf-1025-cd403fee710a",
"text" : // manufacturer
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_0102bca4-46c1-a6bf-1025-cd403fee710a\"> </a><p><b>Generated Narrative: Organization</b><a name=\"0102bca4-46c1-a6bf-1025-cd403fee710a\"> </a><a name=\"hc0102bca4-46c1-a6bf-1025-cd403fee710a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization "0102bca4-46c1-a6bf-1025-cd403fee710a" </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3010027650</p><p><b>active</b>: true</p><p><b>type</b>: Drug Product Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-product-manufacture)</span></p><p><b>name</b>: AAA Pharmaceutical, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>681 Main Street Lumberton New Jersey 08048 USA </td></tr></table></div>"
},
"identifier" : [
{
"system" : "urn:oid:2.16.840.1.113883.4.82",
"value" : "3010027650"
}
],
"active" : true,
"type" : [
// FDA establishment identifier
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
"code" : "drug-product-manufacture",
"display" : "Drug Product Manufacture"
}
]
}
],
"name" : "AAA Pharmaceutical, Inc.",
"contact" : [
{
"address" : {
"line" : [
"681 Main Street"
],
"city" : "Lumberton",
"state" : "New Jersey",
"postalCode" : "08048",
"country" : "USA"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b07",
"resource" : {
"resourceType" : "Organization",
"id" : "378fbe5f-5926-3a5c-4c64-5428df877b07",
"text" : // packaging
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_378fbe5f-5926-3a5c-4c64-5428df877b07\"> </a><p><b>Generated Narrative: Organization</b><a name=\"378fbe5f-5926-3a5c-4c64-5428df877b07\"> </a><a name=\"hc378fbe5f-5926-3a5c-4c64-5428df877b07\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization "378fbe5f-5926-3a5c-4c64-5428df877b07" </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3008816891</p><p><b>active</b>: true</p><p><b>type</b>: Packaging <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#packaging)</span></p><p><b>name</b>: MySite</p></div>"
},
"identifier" : [
{
"system" : "urn:oid:2.16.840.1.113883.4.82",
"value" : "3008816891"
}
],
"active" : true,
"type" : [
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
"code" : "packaging",
"display" : "Packaging"
}
]
}
],
"name" : "MySite"
}
},
{
"fullUrl" : "urn:uuid:b664977d-799d-a1ce-928a-5def2a9955bd",
"resource" : {
"resourceType" : "DiagnosticReport",
"id" : "batchAnalysisReport",
"text" : // ideally this wants a subject, but it can only be a Medication (batch) and we have multiple.
however the observations themselves do have subjects
{
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_batchAnalysisReport\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"batchAnalysisReport\"> </a><a name=\"hcbatchAnalysisReport\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport "batchAnalysisReport" </p></div><p><b>Triggered by</b>: See on this page: PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</p><p><b>status</b>: final</p><p><b>code</b>: Batch Analysis Report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-report-type.html\">Pharmaceutical Report Type Codes</a>#Batch Analysis Report)</span></p><p><b>effective</b>: 2020-12</p><p><b>result</b>: </p><ul><li>See on this page: Observation/18c2d9e0-08c7-84e2-5e59-8f56321f895d</li><li>See on this page: Observation/ba1b4227-8a67-a605-1152-e86e4d614fc3</li><li>See on this page: Observation/2d628dc2-0b9e-9494-55b3-2621e50938c5</li><li>See on this page: Observation/f0a04328-905c-4ec5-372e-4d6cfef18629</li><li>See on this page: Observation/5e5a5e67-7fc6-0064-1be9-5d9d14d887e5</li><li>See on this page: Observation/cfde6776-673c-72e2-68c4-07b77cd85b74</li><li>See on this page: Observation/9c56948a-1a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/1e20aed7-7626-1664-8d96-235f860d9a2c</li><li>See on this page: Observation/ec6d7e30-4d70-491b-0669-a613eedd3c60</li><li>See on this page: Observation/ab7997fa-7b46-1175-3f01-6f6997f7878a</li><li>See on this page: Observation/4052f28b-64a2-392d-35e4-ec8e912434d2</li><li>See on this page: Observation/34ebc51d-8105-0589-3c8d-e7aa6bd0a06c</li><li>See on this page: Observation/2940bf11-05bf-6ce2-3c64-457d0d1f9913</li><li>See on this page: Observation/332b1e76-6f70-2b4e-5d0c-f22a0e042d3e</li><li>See on this page: Observation/f0a13a3b-2e8b-594f-6874-6050511e4c57</li><li>See on this page: Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a795</li><li>See on this page: Observation/be016630-8754-7414-9014-21e020ad66c6</li><li>See on this page: Observation/92568f68-78f3-908c-6935-ff5f3d574dd6</li><li>See on this page: Observation/a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12</li><li>See on this page: Observation/d8533dcb-03f8-5997-6ccf-4f9b6f7a5745</li><li>See on this page: Observation/7cec19a2-34a7-6b80-3d60-083b2cc64fcb</li><li>See on this page: Observation/27aa47fd-7964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/6a78bcde-4781-226c-946e-a4b6915c1899</li><li>See on this page: Observation/f9f11088-7527-947c-3d3f-e71b32e13c78</li><li>See on this page: Observation/7316e094-2094-5710-4f11-75d3effc995e</li><li>See on this page: Observation/1cedf9c1-8e89-5dbb-0e1f-0363a9ca4893</li><li>See on this page: Observation/c350f0b1-9495-0165-2555-83ebd79da682</li><li>See on this page: Observation/4b97e406-3fb0-9f65-0979-910ea1b9254f</li><li>See on this page: Observation/bbfc28df-49bc-986c-1a0e-75e3160268b9</li><li>See on this page: Observation/d6955449-16b4-107f-851d-2f99d0b47b96</li><li>See on this page: Observation/591f5d75-1b2f-299b-6885-f325e4228bda</li><li>See on this page: Observation/1dd8e506-08cf-8a15-8cd0-7c7cf1d88731</li><li>See on this page: Observation/ae0676b9-8ce4-7c72-135e-1fa9ea7f42c3</li><li>See on this page: Observation/d136c4f5-62da-81eb-4fc8-144f9182589e</li><li>See on this page: Observation/3ab5e4eb-673b-0e66-3d2c-86d64ced0e86</li><li>See on this page: Observation/cec7ce65-57d7-a654-9ad6-21d162186eb9</li><li>See on this page: Observation/66c2f585-678e-78b8-2235-1a3b37bd6e46</li><li>See on this page: Observation/f8232d25-023d-679f-9c58-a6dc234b7a28</li><li>See on this page: Observation/368b82be-75dd-1d97-3dbc-a7eed9869daa</li></ul><p><b>conclusion</b>: The samples have been assessed and the conclusion is...</p></div>"
},
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
"valueReference" : {
"reference" : "PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f"
}
}
],
"status" : "final",
"code" : // PlanDefinition/specificationProtocol
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-report-type",
"code" : "Batch Analysis Report",
"display" : "Batch Analysis Report"
}
]
},
"effectiveDateTime" : "2020-12",
"result" : [
// start of stability test
{
"reference" : "Observation/18c2d9e0-08c7-84e2-5e59-8f56321f895d"
},
// Observation/observationDescription
{
"reference" : "Observation/ba1b4227-8a67-a605-1152-e86e4d614fc3"
},
// Observation/observationDescription2
{
"reference" : "Observation/2d628dc2-0b9e-9494-55b3-2621e50938c5"
},
// Observation/observationDescription3
{
"reference" : "Observation/f0a04328-905c-4ec5-372e-4d6cfef18629"
},
// Observation/observationIdentification
{
"reference" : "Observation/5e5a5e67-7fc6-0064-1be9-5d9d14d887e5"
},
// Observation/observationIdentification2
{
"reference" : "Observation/cfde6776-673c-72e2-68c4-07b77cd85b74"
},
// Observation/observationIdentification3
{
"reference" : "Observation/9c56948a-1a39-6609-1c01-4d197ea57a33"
},
// Observation/observationAssay
{
"reference" : "Observation/1e20aed7-7626-1664-8d96-235f860d9a2c"
},
// Observation/observationAssay2
{
"reference" : "Observation/ec6d7e30-4d70-491b-0669-a613eedd3c60"
},
// Observation/observationAssay3
{
"reference" : "Observation/ab7997fa-7b46-1175-3f01-6f6997f7878a"
},
// Observation/observationDegradation-imp1
{
"reference" : "Observation/4052f28b-64a2-392d-35e4-ec8e912434d2"
},
// Observation/observationDegradation-imp1-2
{
"reference" : "Observation/34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"
},
// Observation/observationDegradation-imp1-3
{
"reference" : "Observation/2940bf11-05bf-6ce2-3c64-457d0d1f9913"
},
// Observation/observationDegradation-imp2
{
"reference" : "Observation/332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"
},
// Observation/observationDegradation-imp2-2
{
"reference" : "Observation/f0a13a3b-2e8b-594f-6874-6050511e4c57"
},
// Observation/observationDegradation-imp2-3
{
"reference" : "Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a795"
},
// Observation/observationDegradation-imp3
{
"reference" : "Observation/be016630-8754-7414-9014-21e020ad66c6"
},
// Observation/observationDegradation-imp3-2
{
"reference" : "Observation/92568f68-78f3-908c-6935-ff5f3d574dd6"
},
// Observation/observationDegradation-imp3-3
{
"reference" : "Observation/a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"
},
// Observation/observationDegradation-imp-unspecified
{
"reference" : "Observation/d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"
},
// Observation/observationDegradation-imp-unspecified-2
{
"reference" : "Observation/7cec19a2-34a7-6b80-3d60-083b2cc64fcb"
},
// Observation/observationDegradation-imp-unspecified-3
{
"reference" : "Observation/27aa47fd-7964-4f96-6495-b2bec7f160e7"
},
// Observation/observationDegradation-imp-total
{
"reference" : "Observation/6a78bcde-4781-226c-946e-a4b6915c1899"
},
// Observation/observationDegradation-imp-total-2
{
"reference" : "Observation/f9f11088-7527-947c-3d3f-e71b32e13c78"
},
// Observation/observationDegradation-imp-total-3
{
"reference" : "Observation/7316e094-2094-5710-4f11-75d3effc995e"
},
// Observation/observationDissolution
{
"reference" : "Observation/1cedf9c1-8e89-5dbb-0e1f-0363a9ca4893"
},
// Observation/observationDissolution2
{
"reference" : "Observation/c350f0b1-9495-0165-2555-83ebd79da682"
},
// Observation/observationDissolution3
{
"reference" : "Observation/4b97e406-3fb0-9f65-0979-910ea1b9254f"
},
// Observation/observationDissolutionQ80
{
"reference" : "Observation/bbfc28df-49bc-986c-1a0e-75e3160268b9"
},
// Observation/observationDissolutionQ802
{
"reference" : "Observation/d6955449-16b4-107f-851d-2f99d0b47b96"
},
// Observation/observationDissolutionQ803
{
"reference" : "Observation/591f5d75-1b2f-299b-6885-f325e4228bda"
},
// Observation/observationUniformity
{
"reference" : "Observation/1dd8e506-08cf-8a15-8cd0-7c7cf1d88731"
},
// Observation/observationUniformity2
{
"reference" : "Observation/ae0676b9-8ce4-7c72-135e-1fa9ea7f42c3"
},
// Observation/observationUniformity3
{
"reference" : "Observation/d136c4f5-62da-81eb-4fc8-144f9182589e"
},
// Observation/observationMicro
{
"reference" : "Observation/3ab5e4eb-673b-0e66-3d2c-86d64ced0e86"
},
// Observation/observationMicro2
{
"reference" : "Observation/cec7ce65-57d7-a654-9ad6-21d162186eb9"
},
// Observation/observationMicro3
{
"reference" : "Observation/66c2f585-678e-78b8-2235-1a3b37bd6e46"
},
// Observation/observationWater
{
"reference" : "Observation/f8232d25-023d-679f-9c58-a6dc234b7a28"
},
// Observation/observationWater2
{
"reference" : "Observation/368b82be-75dd-1d97-3dbc-a7eed9869daa"
}
],
"conclusion" : "The samples have been assessed and the conclusion is..."
}
},
// Observation/observationWater3
{
"fullUrl" : "urn:uuid:18c2d9e0-08c7-84e2-5e59-8f56321f895d",
"resource" : {
"resourceType" : "Observation",
"id" : "18c2d9e0-08c7-84e2-5e59-8f56321f895d",
"text" : // observationDescription
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_18c2d9e0-08c7-84e2-5e59-8f56321f895d\"> </a><p><b>Generated Narrative: Observation</b><a name=\"18c2d9e0-08c7-84e2-5e59-8f56321f895d\"> </a><a name=\"hc18c2d9e0-08c7-84e2-5e59-8f56321f895d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "18c2d9e0-08c7-84e2-5e59-8f56321f895d" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc07b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/fc07b5d5-9fe1-91c2-2d06-47cb5b295e72"
},
"status" : "final",
"code" : // ObservationDefinition/Description
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DESC",
"display" : "Description"
}
],
"text" : "Description"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:ba1b4227-8a67-a605-1152-e86e4d614fc3",
"resource" : {
"resourceType" : "Observation",
"id" : "ba1b4227-8a67-a605-1152-e86e4d614fc3",
"text" : // observationDescription2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ba1b4227-8a67-a605-1152-e86e4d614fc3\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ba1b4227-8a67-a605-1152-e86e4d614fc3\"> </a><a name=\"hcba1b4227-8a67-a605-1152-e86e4d614fc3\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "ba1b4227-8a67-a605-1152-e86e4d614fc3" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc07b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Does not comply <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/fc07b5d5-9fe1-91c2-2d06-47cb5b295e72"
},
"status" : "final",
"code" : // ObservationDefinition/Description
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DESC",
"display" : "Description"
}
],
"text" : "Description"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Does not comply"
}
}
},
{
"fullUrl" : "urn:uuid:2d628dc2-0b9e-9494-55b3-2621e50938c5",
"resource" : {
"resourceType" : "Observation",
"id" : "2d628dc2-0b9e-9494-55b3-2621e50938c5",
"text" : // observationDescription3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_2d628dc2-0b9e-9494-55b3-2621e50938c5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"2d628dc2-0b9e-9494-55b3-2621e50938c5\"> </a><a name=\"hc2d628dc2-0b9e-9494-55b3-2621e50938c5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "2d628dc2-0b9e-9494-55b3-2621e50938c5" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc07b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/fc07b5d5-9fe1-91c2-2d06-47cb5b295e72"
},
"status" : "final",
"code" : // ObservationDefinition/Description
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DESC",
"display" : "Description"
}
],
"text" : "Description"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:f0a04328-905c-4ec5-372e-4d6cfef18629",
"resource" : {
"resourceType" : "Observation",
"id" : "f0a04328-905c-4ec5-372e-4d6cfef18629",
"text" : // observationIdentification
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f0a04328-905c-4ec5-372e-4d6cfef18629\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f0a04328-905c-4ec5-372e-4d6cfef18629\"> </a><a name=\"hcf0a04328-905c-4ec5-372e-4d6cfef18629\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "f0a04328-905c-4ec5-372e-4d6cfef18629" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"
},
"status" : "final",
"code" : // ObservationDefinition/Identification
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IDT",
"display" : "Identification"
}
],
"text" : "Identification"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:5e5a5e67-7fc6-0064-1be9-5d9d14d887e5",
"resource" : {
"resourceType" : "Observation",
"id" : "5e5a5e67-7fc6-0064-1be9-5d9d14d887e5",
"text" : // observationIdentification2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_5e5a5e67-7fc6-0064-1be9-5d9d14d887e5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"5e5a5e67-7fc6-0064-1be9-5d9d14d887e5\"> </a><a name=\"hc5e5a5e67-7fc6-0064-1be9-5d9d14d887e5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "5e5a5e67-7fc6-0064-1be9-5d9d14d887e5" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Does not comply <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"
},
"status" : "final",
"code" : // ObservationDefinition/Identification
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IDT",
"display" : "Identification"
}
],
"text" : "Identification"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Does not comply"
}
}
},
{
"fullUrl" : "urn:uuid:cfde6776-673c-72e2-68c4-07b77cd85b74",
"resource" : {
"resourceType" : "Observation",
"id" : "cfde6776-673c-72e2-68c4-07b77cd85b74",
"text" : // observationIdentification3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_cfde6776-673c-72e2-68c4-07b77cd85b74\"> </a><p><b>Generated Narrative: Observation</b><a name=\"cfde6776-673c-72e2-68c4-07b77cd85b74\"> </a><a name=\"hccfde6776-673c-72e2-68c4-07b77cd85b74\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "cfde6776-673c-72e2-68c4-07b77cd85b74" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"
},
"status" : "final",
"code" : // ObservationDefinition/Identification
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IDT",
"display" : "Identification"
}
],
"text" : "Identification"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:9c56948a-1a39-6609-1c01-4d197ea57a33",
"resource" : {
"resourceType" : "Observation",
"id" : "9c56948a-1a39-6609-1c01-4d197ea57a33",
"text" : // observationAssay
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-1a39-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-1a39-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-1a39-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "9c56948a-1a39-6609-1c01-4d197ea57a33" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/39ffd548-bb3d-43b9-9ca9-83f26631712b</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 103 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/39ffd548-bb3d-43b9-9ca9-83f26631712b"
},
"status" : "final",
"code" : // ObservationDefinition/Assay
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "ASSAY",
"display" : "Assay"
}
],
"text" : "Assay"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 103,
"unit" : "%",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"fullUrl" : "urn:uuid:1e20aed7-7626-1664-8d96-235f860d9a2c",
"resource" : {
"resourceType" : "Observation",
"id" : "1e20aed7-7626-1664-8d96-235f860d9a2c",
"text" : // observationAssay2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_1e20aed7-7626-1664-8d96-235f860d9a2c\"> </a><p><b>Generated Narrative: Observation</b><a name=\"1e20aed7-7626-1664-8d96-235f860d9a2c\"> </a><a name=\"hc1e20aed7-7626-1664-8d96-235f860d9a2c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "1e20aed7-7626-1664-8d96-235f860d9a2c" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/39ffd548-bb3d-43b9-9ca9-83f26631712b</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 102 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/39ffd548-bb3d-43b9-9ca9-83f26631712b"
},
"status" : "final",
"code" : // ObservationDefinition/Assay
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "ASSAY",
"display" : "Assay"
}
],
"text" : "Assay"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 102,
"unit" : "%",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"fullUrl" : "urn:uuid:ec6d7e30-4d70-491b-0669-a613eedd3c60",
"resource" : {
"resourceType" : "Observation",
"id" : "ec6d7e30-4d70-491b-0669-a613eedd3c60",
"text" : // observationAssay3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ec6d7e30-4d70-491b-0669-a613eedd3c60\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ec6d7e30-4d70-491b-0669-a613eedd3c60\"> </a><a name=\"hcec6d7e30-4d70-491b-0669-a613eedd3c60\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "ec6d7e30-4d70-491b-0669-a613eedd3c60" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/39ffd548-bb3d-43b9-9ca9-83f26631712b</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 101 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/39ffd548-bb3d-43b9-9ca9-83f26631712b"
},
"status" : "final",
"code" : // ObservationDefinition/Assay
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "ASSAY",
"display" : "Assay"
}
],
"text" : "Assay"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 101,
"unit" : "%",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"fullUrl" : "urn:uuid:ab7997fa-7b46-1175-3f01-6f6997f7878a",
"resource" : {
"resourceType" : "Observation",
"id" : "ab7997fa-7b46-1175-3f01-6f6997f7878a",
"text" : // observationDegradation-imp1
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ab7997fa-7b46-1175-3f01-6f6997f7878a\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ab7997fa-7b46-1175-3f01-6f6997f7878a\"> </a><a name=\"hcab7997fa-7b46-1175-3f01-6f6997f7878a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "ab7997fa-7b46-1175-3f01-6f6997f7878a" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.1,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Impurity 1"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:4052f28b-64a2-392d-35e4-ec8e912434d2",
"resource" : {
"resourceType" : "Observation",
"id" : "4052f28b-64a2-392d-35e4-ec8e912434d2",
"text" : // observationDegradation-imp1-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_4052f28b-64a2-392d-35e4-ec8e912434d2\"> </a><p><b>Generated Narrative: Observation</b><a name=\"4052f28b-64a2-392d-35e4-ec8e912434d2\"> </a><a name=\"hc4052f28b-64a2-392d-35e4-ec8e912434d2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "4052f28b-64a2-392d-35e4-ec8e912434d2" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.2,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Impurity 1"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:34ebc51d-8105-0589-3c8d-e7aa6bd0a06c",
"resource" : {
"resourceType" : "Observation",
"id" : "34ebc51d-8105-0589-3c8d-e7aa6bd0a06c",
"text" : // observationDegradation-imp1-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_34ebc51d-8105-0589-3c8d-e7aa6bd0a06c\"> </a><p><b>Generated Narrative: Observation</b><a name=\"34ebc51d-8105-0589-3c8d-e7aa6bd0a06c\"> </a><a name=\"hc34ebc51d-8105-0589-3c8d-e7aa6bd0a06c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "34ebc51d-8105-0589-3c8d-e7aa6bd0a06c" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.2,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Impurity 1"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:2940bf11-05bf-6ce2-3c64-457d0d1f9913",
"resource" : {
"resourceType" : "Observation",
"id" : "2940bf11-05bf-6ce2-3c64-457d0d1f9913",
"text" : // observationDegradation-imp2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_2940bf11-05bf-6ce2-3c64-457d0d1f9913\"> </a><p><b>Generated Narrative: Observation</b><a name=\"2940bf11-05bf-6ce2-3c64-457d0d1f9913\"> </a><a name=\"hc2940bf11-05bf-6ce2-3c64-457d0d1f9913\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "2940bf11-05bf-6ce2-3c64-457d0d1f9913" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.2,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Impurity 2"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:332b1e76-6f70-2b4e-5d0c-f22a0e042d3e",
"resource" : {
"resourceType" : "Observation",
"id" : "332b1e76-6f70-2b4e-5d0c-f22a0e042d3e",
"text" : // observationDegradation-imp2-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_332b1e76-6f70-2b4e-5d0c-f22a0e042d3e\"> </a><p><b>Generated Narrative: Observation</b><a name=\"332b1e76-6f70-2b4e-5d0c-f22a0e042d3e\"> </a><a name=\"hc332b1e76-6f70-2b4e-5d0c-f22a0e042d3e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "332b1e76-6f70-2b4e-5d0c-f22a0e042d3e" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.2,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Impurity 2"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:f0a13a3b-2e8b-594f-6874-6050511e4c57",
"resource" : {
"resourceType" : "Observation",
"id" : "f0a13a3b-2e8b-594f-6874-6050511e4c57",
"text" : // observationDegradation-imp2-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f0a13a3b-2e8b-594f-6874-6050511e4c57\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f0a13a3b-2e8b-594f-6874-6050511e4c57\"> </a><a name=\"hcf0a13a3b-2e8b-594f-6874-6050511e4c57\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "f0a13a3b-2e8b-594f-6874-6050511e4c57" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.2,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Impurity 2"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:7fe7ccd7-6449-0186-2282-3eeb4cf6a795",
"resource" : {
"resourceType" : "Observation",
"id" : "7fe7ccd7-6449-0186-2282-3eeb4cf6a795",
"text" : // observationDegradation-imp3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_7fe7ccd7-6449-0186-2282-3eeb4cf6a795\"> </a><p><b>Generated Narrative: Observation</b><a name=\"7fe7ccd7-6449-0186-2282-3eeb4cf6a795\"> </a><a name=\"hc7fe7ccd7-6449-0186-2282-3eeb4cf6a795\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "7fe7ccd7-6449-0186-2282-3eeb4cf6a795" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.2,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Impurity 3"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:be016630-8754-7414-9014-21e020ad66c6",
"resource" : {
"resourceType" : "Observation",
"id" : "be016630-8754-7414-9014-21e020ad66c6",
"text" : // observationDegradation-imp3-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_be016630-8754-7414-9014-21e020ad66c6\"> </a><p><b>Generated Narrative: Observation</b><a name=\"be016630-8754-7414-9014-21e020ad66c6\"> </a><a name=\"hcbe016630-8754-7414-9014-21e020ad66c6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "be016630-8754-7414-9014-21e020ad66c6" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.2,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Impurity 3"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:92568f68-78f3-908c-6935-ff5f3d574dd6",
"resource" : {
"resourceType" : "Observation",
"id" : "92568f68-78f3-908c-6935-ff5f3d574dd6",
"text" : // observationDegradation-imp3-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_92568f68-78f3-908c-6935-ff5f3d574dd6\"> </a><p><b>Generated Narrative: Observation</b><a name=\"92568f68-78f3-908c-6935-ff5f3d574dd6\"> </a><a name=\"hc92568f68-78f3-908c-6935-ff5f3d574dd6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "92568f68-78f3-908c-6935-ff5f3d574dd6" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.2,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Impurity 3"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12",
"resource" : {
"resourceType" : "Observation",
"id" : "a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12",
"text" : // observationDegradation-imp-unspecified
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12\"> </a><p><b>Generated Narrative: Observation</b><a name=\"a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12\"> </a><a name=\"hca0ba0f6d-8ec0-846a-a70d-f6bca6d01a12\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Individual unspecified degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.1,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Individual unspecified degradation products"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:d8533dcb-03f8-5997-6ccf-4f9b6f7a5745",
"resource" : {
"resourceType" : "Observation",
"id" : "d8533dcb-03f8-5997-6ccf-4f9b6f7a5745",
"text" : // observationDegradation-imp-unspecified-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_d8533dcb-03f8-5997-6ccf-4f9b6f7a5745\"> </a><p><b>Generated Narrative: Observation</b><a name=\"d8533dcb-03f8-5997-6ccf-4f9b6f7a5745\"> </a><a name=\"hcd8533dcb-03f8-5997-6ccf-4f9b6f7a5745\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "d8533dcb-03f8-5997-6ccf-4f9b6f7a5745" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Individual unspecified degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.1,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Individual unspecified degradation products"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:7cec19a2-34a7-6b80-3d60-083b2cc64fcb",
"resource" : {
"resourceType" : "Observation",
"id" : "7cec19a2-34a7-6b80-3d60-083b2cc64fcb",
"text" : // observationDegradation-imp-unspecified-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_7cec19a2-34a7-6b80-3d60-083b2cc64fcb\"> </a><p><b>Generated Narrative: Observation</b><a name=\"7cec19a2-34a7-6b80-3d60-083b2cc64fcb\"> </a><a name=\"hc7cec19a2-34a7-6b80-3d60-083b2cc64fcb\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "7cec19a2-34a7-6b80-3d60-083b2cc64fcb" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Individual unspecified degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.1,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Individual unspecified degradation products"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:27aa47fd-7964-4f96-6495-b2bec7f160e7",
"resource" : {
"resourceType" : "Observation",
"id" : "27aa47fd-7964-4f96-6495-b2bec7f160e7",
"text" : // observationDegradation-imp-total
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_27aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"27aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc27aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "27aa47fd-7964-4f96-6495-b2bec7f160e7" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.6 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.6,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Total degradation products"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:6a78bcde-4781-226c-946e-a4b6915c1899",
"resource" : {
"resourceType" : "Observation",
"id" : "6a78bcde-4781-226c-946e-a4b6915c1899",
"text" : // observationDegradation-imp-total-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_6a78bcde-4781-226c-946e-a4b6915c1899\"> </a><p><b>Generated Narrative: Observation</b><a name=\"6a78bcde-4781-226c-946e-a4b6915c1899\"> </a><a name=\"hc6a78bcde-4781-226c-946e-a4b6915c1899\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "6a78bcde-4781-226c-946e-a4b6915c1899" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.7 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.7,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Total degradation products"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:f9f11088-7527-947c-3d3f-e71b32e13c78",
"resource" : {
"resourceType" : "Observation",
"id" : "f9f11088-7527-947c-3d3f-e71b32e13c78",
"text" : // observationDegradation-imp-total-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f9f11088-7527-947c-3d3f-e71b32e13c78\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f9f11088-7527-947c-3d3f-e71b32e13c78\"> </a><a name=\"hcf9f11088-7527-947c-3d3f-e71b32e13c78\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "f9f11088-7527-947c-3d3f-e71b32e13c78" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.6 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total degradation products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"
},
"status" : "final",
"code" : // ObservationDefinition/Degradation
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.6,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"text" : "Total degradation products"
}
}
]
}
},
// could have the code of an impurity substance, or could have an extension to point to it as a resource
{
"fullUrl" : "urn:uuid:7316e094-2094-5710-4f11-75d3effc995e",
"resource" : {
"resourceType" : "Observation",
"id" : "7316e094-2094-5710-4f11-75d3effc995e",
"text" : // observationDissolution
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_7316e094-2094-5710-4f11-75d3effc995e\"> </a><p><b>Generated Narrative: Observation</b><a name=\"7316e094-2094-5710-4f11-75d3effc995e\"> </a><a name=\"hc7316e094-2094-5710-4f11-75d3effc995e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "7316e094-2094-5710-4f11-75d3effc995e" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8f5d8abf-2cf4-8617-1e41-a74d90210dcc</p><p><b>status</b>: final</p><p><b>code</b>: Dissolution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Dissolution)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8f5d8abf-2cf4-8617-1e41-a74d90210dcc"
},
"status" : "final",
"code" : // ObservationDefinition/Dissolution
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Dissolution",
"display" : "Dissolution"
}
],
"text" : "Dissolution"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:1cedf9c1-8e89-5dbb-0e1f-0363a9ca4893",
"resource" : {
"resourceType" : "Observation",
"id" : "1cedf9c1-8e89-5dbb-0e1f-0363a9ca4893",
"text" : // observationDissolution2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_1cedf9c1-8e89-5dbb-0e1f-0363a9ca4893\"> </a><p><b>Generated Narrative: Observation</b><a name=\"1cedf9c1-8e89-5dbb-0e1f-0363a9ca4893\"> </a><a name=\"hc1cedf9c1-8e89-5dbb-0e1f-0363a9ca4893\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "1cedf9c1-8e89-5dbb-0e1f-0363a9ca4893" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8f5d8abf-2cf4-8617-1e41-a74d90210dcc</p><p><b>status</b>: final</p><p><b>code</b>: Dissolution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Dissolution)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8f5d8abf-2cf4-8617-1e41-a74d90210dcc"
},
"status" : "final",
"code" : // ObservationDefinition/Dissolution
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Dissolution",
"display" : "Dissolution"
}
],
"text" : "Dissolution"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:c350f0b1-9495-0165-2555-83ebd79da682",
"resource" : {
"resourceType" : "Observation",
"id" : "c350f0b1-9495-0165-2555-83ebd79da682",
"text" : // observationDissolution3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_c350f0b1-9495-0165-2555-83ebd79da682\"> </a><p><b>Generated Narrative: Observation</b><a name=\"c350f0b1-9495-0165-2555-83ebd79da682\"> </a><a name=\"hcc350f0b1-9495-0165-2555-83ebd79da682\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "c350f0b1-9495-0165-2555-83ebd79da682" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8f5d8abf-2cf4-8617-1e41-a74d90210dcc</p><p><b>status</b>: final</p><p><b>code</b>: Dissolution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Dissolution)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/8f5d8abf-2cf4-8617-1e41-a74d90210dcc"
},
"status" : "final",
"code" : // ObservationDefinition/Dissolution
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Dissolution",
"display" : "Dissolution"
}
],
"text" : "Dissolution"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:4b97e406-3fb0-9f65-0979-910ea1b9254f",
"resource" : {
"resourceType" : "Observation",
"id" : "4b97e406-3fb0-9f65-0979-910ea1b9254f",
"text" : // observationDissolutionQ80
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_4b97e406-3fb0-9f65-0979-910ea1b9254f\"> </a><p><b>Generated Narrative: Observation</b><a name=\"4b97e406-3fb0-9f65-0979-910ea1b9254f\"> </a><a name=\"hc4b97e406-3fb0-9f65-0979-910ea1b9254f\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "4b97e406-3fb0-9f65-0979-910ea1b9254f" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/33a9d578-6e6b-7606-72bc-6775d36c1930</p><p><b>status</b>: final</p><p><b>code</b>: Dissolution Quantity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Dissolution Quantity)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 90 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/33a9d578-6e6b-7606-72bc-6775d36c1930"
},
"status" : "final",
"code" : // ObservationDefinition/DissolutionQ80
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Dissolution Quantity",
"display" : "Dissolution Quantity"
}
]
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 90,
"unit" : "%",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"fullUrl" : "urn:uuid:bbfc28df-49bc-986c-1a0e-75e3160268b9",
"resource" : {
"resourceType" : "Observation",
"id" : "bbfc28df-49bc-986c-1a0e-75e3160268b9",
"text" : // observationDissolutionQ802
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_bbfc28df-49bc-986c-1a0e-75e3160268b9\"> </a><p><b>Generated Narrative: Observation</b><a name=\"bbfc28df-49bc-986c-1a0e-75e3160268b9\"> </a><a name=\"hcbbfc28df-49bc-986c-1a0e-75e3160268b9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "bbfc28df-49bc-986c-1a0e-75e3160268b9" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/33a9d578-6e6b-7606-72bc-6775d36c1930</p><p><b>status</b>: final</p><p><b>code</b>: Dissolution Quantity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Dissolution Quantity)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 92 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/33a9d578-6e6b-7606-72bc-6775d36c1930"
},
"status" : "final",
"code" : // ObservationDefinition/DissolutionQ80
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Dissolution Quantity",
"display" : "Dissolution Quantity"
}
]
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 92,
"unit" : "%",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"fullUrl" : "urn:uuid:d6955449-16b4-107f-851d-2f99d0b47b96",
"resource" : {
"resourceType" : "Observation",
"id" : "d6955449-16b4-107f-851d-2f99d0b47b96",
"text" : // observationDissolutionQ803
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_d6955449-16b4-107f-851d-2f99d0b47b96\"> </a><p><b>Generated Narrative: Observation</b><a name=\"d6955449-16b4-107f-851d-2f99d0b47b96\"> </a><a name=\"hcd6955449-16b4-107f-851d-2f99d0b47b96\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "d6955449-16b4-107f-851d-2f99d0b47b96" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/33a9d578-6e6b-7606-72bc-6775d36c1930</p><p><b>status</b>: final</p><p><b>code</b>: Dissolution Quantity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Dissolution Quantity)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 95 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/33a9d578-6e6b-7606-72bc-6775d36c1930"
},
"status" : "final",
"code" : // ObservationDefinition/DissolutionQ80
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Dissolution Quantity",
"display" : "Dissolution Quantity"
}
]
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 95,
"unit" : "%",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"fullUrl" : "urn:uuid:591f5d75-1b2f-299b-6885-f325e4228bda",
"resource" : {
"resourceType" : "Observation",
"id" : "591f5d75-1b2f-299b-6885-f325e4228bda",
"text" : // observationUniformity
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_591f5d75-1b2f-299b-6885-f325e4228bda\"> </a><p><b>Generated Narrative: Observation</b><a name=\"591f5d75-1b2f-299b-6885-f325e4228bda\"> </a><a name=\"hc591f5d75-1b2f-299b-6885-f325e4228bda\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "591f5d75-1b2f-299b-6885-f325e4228bda" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/ef17cff1-6586-a4a4-9168-2602140548d7</p><p><b>status</b>: final</p><p><b>code</b>: uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/ef17cff1-6586-a4a4-9168-2602140548d7"
},
"status" : "final",
"code" : // ObservationDefinition/Uniformity
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "uniformity-dosage",
"display" : "uniformity of dosage units (by weight)"
}
],
"text" : "uniformity of dosage units (by weight)"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:1dd8e506-08cf-8a15-8cd0-7c7cf1d88731",
"resource" : {
"resourceType" : "Observation",
"id" : "1dd8e506-08cf-8a15-8cd0-7c7cf1d88731",
"text" : // observationUniformity2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_1dd8e506-08cf-8a15-8cd0-7c7cf1d88731\"> </a><p><b>Generated Narrative: Observation</b><a name=\"1dd8e506-08cf-8a15-8cd0-7c7cf1d88731\"> </a><a name=\"hc1dd8e506-08cf-8a15-8cd0-7c7cf1d88731\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "1dd8e506-08cf-8a15-8cd0-7c7cf1d88731" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/ef17cff1-6586-a4a4-9168-2602140548d7</p><p><b>status</b>: final</p><p><b>code</b>: uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/ef17cff1-6586-a4a4-9168-2602140548d7"
},
"status" : "final",
"code" : // ObservationDefinition/Uniformity
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "uniformity-dosage",
"display" : "uniformity of dosage units (by weight)"
}
],
"text" : "uniformity of dosage units (by weight)"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:ae0676b9-8ce4-7c72-135e-1fa9ea7f42c3",
"resource" : {
"resourceType" : "Observation",
"id" : "ae0676b9-8ce4-7c72-135e-1fa9ea7f42c3",
"text" : // observationUniformity3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ae0676b9-8ce4-7c72-135e-1fa9ea7f42c3\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ae0676b9-8ce4-7c72-135e-1fa9ea7f42c3\"> </a><a name=\"hcae0676b9-8ce4-7c72-135e-1fa9ea7f42c3\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "ae0676b9-8ce4-7c72-135e-1fa9ea7f42c3" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/ef17cff1-6586-a4a4-9168-2602140548d7</p><p><b>status</b>: final</p><p><b>code</b>: uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/ef17cff1-6586-a4a4-9168-2602140548d7"
},
"status" : "final",
"code" : // ObservationDefinition/Uniformity
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "uniformity-dosage",
"display" : "uniformity of dosage units (by weight)"
}
],
"text" : "uniformity of dosage units (by weight)"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:d136c4f5-62da-81eb-4fc8-144f9182589e",
"resource" : {
"resourceType" : "Observation",
"id" : "d136c4f5-62da-81eb-4fc8-144f9182589e",
"text" : // observationMicro
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_d136c4f5-62da-81eb-4fc8-144f9182589e\"> </a><p><b>Generated Narrative: Observation</b><a name=\"d136c4f5-62da-81eb-4fc8-144f9182589e\"> </a><a name=\"hcd136c4f5-62da-81eb-4fc8-144f9182589e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "d136c4f5-62da-81eb-4fc8-144f9182589e" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d999ee06-6595-762c-1bda-0818ab1c6c0e</p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/d999ee06-6595-762c-1bda-0818ab1c6c0e"
},
"status" : "final",
"code" : // ObservationDefinition/Microbiological
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Microbiological Quality",
"display" : "Microbiological Quality"
}
],
"text" : "Microbiological Quality"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:3ab5e4eb-673b-0e66-3d2c-86d64ced0e86",
"resource" : {
"resourceType" : "Observation",
"id" : "3ab5e4eb-673b-0e66-3d2c-86d64ced0e86",
"text" : // observationMicro2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_3ab5e4eb-673b-0e66-3d2c-86d64ced0e86\"> </a><p><b>Generated Narrative: Observation</b><a name=\"3ab5e4eb-673b-0e66-3d2c-86d64ced0e86\"> </a><a name=\"hc3ab5e4eb-673b-0e66-3d2c-86d64ced0e86\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "3ab5e4eb-673b-0e66-3d2c-86d64ced0e86" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d999ee06-6595-762c-1bda-0818ab1c6c0e</p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/d999ee06-6595-762c-1bda-0818ab1c6c0e"
},
"status" : "final",
"code" : // ObservationDefinition/Microbiological
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Microbiological Quality",
"display" : "Microbiological Quality"
}
],
"text" : "Microbiological Quality"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:cec7ce65-57d7-a654-9ad6-21d162186eb9",
"resource" : {
"resourceType" : "Observation",
"id" : "cec7ce65-57d7-a654-9ad6-21d162186eb9",
"text" : // observationMicro3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_cec7ce65-57d7-a654-9ad6-21d162186eb9\"> </a><p><b>Generated Narrative: Observation</b><a name=\"cec7ce65-57d7-a654-9ad6-21d162186eb9\"> </a><a name=\"hccec7ce65-57d7-a654-9ad6-21d162186eb9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "cec7ce65-57d7-a654-9ad6-21d162186eb9" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d999ee06-6595-762c-1bda-0818ab1c6c0e</p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/d999ee06-6595-762c-1bda-0818ab1c6c0e"
},
"status" : "final",
"code" : // ObservationDefinition/Microbiological
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "Microbiological Quality",
"display" : "Microbiological Quality"
}
],
"text" : "Microbiological Quality"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"text" : "Complies"
}
}
},
{
"fullUrl" : "urn:uuid:66c2f585-678e-78b8-2235-1a3b37bd6e46",
"resource" : {
"resourceType" : "Observation",
"id" : "66c2f585-678e-78b8-2235-1a3b37bd6e46",
"text" : // observationWater
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_66c2f585-678e-78b8-2235-1a3b37bd6e46\"> </a><p><b>Generated Narrative: Observation</b><a name=\"66c2f585-678e-78b8-2235-1a3b37bd6e46\"> </a><a name=\"hc66c2f585-678e-78b8-2235-1a3b37bd6e46\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "66c2f585-678e-78b8-2235-1a3b37bd6e46" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.5 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"
},
"status" : "final",
"code" : // ObservationDefinition/Water
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "WaterContent",
"display" : "Water Content"
}
],
"text" : "Water Content"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.5,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"fullUrl" : "urn:uuid:f8232d25-023d-679f-9c58-a6dc234b7a28",
"resource" : {
"resourceType" : "Observation",
"id" : "f8232d25-023d-679f-9c58-a6dc234b7a28",
"text" : // observationWater2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f8232d25-023d-679f-9c58-a6dc234b7a28\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f8232d25-023d-679f-9c58-a6dc234b7a28\"> </a><a name=\"hcf8232d25-023d-679f-9c58-a6dc234b7a28\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "f8232d25-023d-679f-9c58-a6dc234b7a28" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.5 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"
},
"status" : "final",
"code" : // ObservationDefinition/Water
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "WaterContent",
"display" : "Water Content"
}
],
"text" : "Water Content"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.5,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"fullUrl" : "urn:uuid:368b82be-75dd-1d97-3dbc-a7eed9869daa",
"resource" : {
"resourceType" : "Observation",
"id" : "368b82be-75dd-1d97-3dbc-a7eed9869daa",
"text" : // observationWater3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_368b82be-75dd-1d97-3dbc-a7eed9869daa\"> </a><p><b>Generated Narrative: Observation</b><a name=\"368b82be-75dd-1d97-3dbc-a7eed9869daa\"> </a><a name=\"hc368b82be-75dd-1d97-3dbc-a7eed9869daa\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "368b82be-75dd-1d97-3dbc-a7eed9869daa" </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.5 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
},
"instantiatesReference" : {
"reference" : "ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"
},
"status" : "final",
"code" : // ObservationDefinition/Water
{
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
"code" : "WaterContent",
"display" : "Water Content"
}
],
"text" : "Water Content"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
}
],
"valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
{
"value" : 0.5,
"unit" : "% w/w",
"system" : "http://unitsofmeasure.org",
"code" : "%"
}
}
},
{
"fullUrl" : "urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5",
"resource" : // Section 1.1 - DP Identification
{
"resourceType" : "MedicinalProductDefinition",
"id" : "a0694a7a-aafa-4cbe-8135-c788a9a4d3d5",
"text" : // medicinalproductdefinition-drug-product-pq-ex1
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicinalProductDefinition_a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a><p><b>Generated Narrative: MedicinalProductDefinition</b><a name=\"a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a><a name=\"hca0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicinalProductDefinition "a0694a7a-aafa-4cbe-8135-c788a9a4d3d5" </p></div><p><b>description</b>: Textual description of the product</p><p><b>combinedPharmaceuticalDoseForm</b>: Gastro-resistant tablet <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterms.edqm.eu#10225000)</span></p><p><b>route</b>: Oral use <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterms.edqm.eu#20053000)</span></p><blockquote><p><b>name</b></p><p><b>productName</b>: Stelbat Tablets, 20mg</p><p><b>type</b>: Proprietary <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-productNameType-pq-example.html\">Product Name Type - example</a>#Proprietary)</span></p><h3>Parts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Part</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>20mg</td><td>Strength part <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-medicinal-product-name-part-type.html\">Product Name Part Type</a>#StrengthPart)</span></td></tr></table></blockquote></div>"
},
"description" : "Textual description of the product",
"combinedPharmaceuticalDoseForm" : {
"coding" : [
{
"system" : "http://standardterms.edqm.eu",
"code" : "10225000",
"display" : "Gastro-resistant tablet"
}
]
},
"route" : [
{
"coding" : [
{
"system" : "http://standardterms.edqm.eu",
"code" : "20053000",
"display" : "Oral use"
}
]
}
],
"name" : [
{
"productName" : "Stelbat Tablets, 20mg",
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-productNameType-pq-example",
"code" : "Proprietary",
"display" : "Proprietary"
}
]
},
"part" : [
{
"part" : "20mg",
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/medicinal-product-name-part-type",
"code" : "StrengthPart",
"display" : "Strength part"
}
]
}
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d6",
"resource" : {
"resourceType" : "Ingredient",
"id" : "a0694a7a-aafa-4cbe-8135-c788a9a4d3d6",
"text" : // productIngredient
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_a0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a><p><b>Generated Narrative: Ingredient</b><a name=\"a0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a><a name=\"hca0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Ingredient "a0694a7a-aafa-4cbe-8135-c788a9a4d3d6" </p></div><p><b>status</b>: active</p><p><b>for</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>role</b>: Active <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-ingredient-role.html\">Ingredient Role</a>#100000072072)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/6eb94d34-48b4-5bb0-4c05-e183d2ea3e95</td></tr></table></blockquote></div>"
},
"status" : "active",
"for" : [
{
"reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
}
],
"role" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
{
"coding" : [
{
"system" : "http://hl7.org/fhir/ingredient-role",
"code" : "100000072072",
"display" : "Active"
}
]
},
"substance" : {
"code" : {
"reference" : {
"reference" : "SubstanceDefinition/6eb94d34-48b4-5bb0-4c05-e183d2ea3e95"
}
}
}
}
},
// SubstanceDefinition/substance1
{
"fullUrl" : "urn:uuid:6eb94d34-48b4-5bb0-4c05-e183d2ea3e95",
"resource" : {
"resourceType" : "SubstanceDefinition",
"id" : "6eb94d34-48b4-5bb0-4c05-e183d2ea3e95",
"text" : // substance1
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_6eb94d34-48b4-5bb0-4c05-e183d2ea3e95\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"6eb94d34-48b4-5bb0-4c05-e183d2ea3e95\"> </a><a name=\"hc6eb94d34-48b4-5bb0-4c05-e183d2ea3e95\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "6eb94d34-48b4-5bb0-4c05-e183d2ea3e95" </p></div><p><b>manufacturer</b>: See on this page: Organization/23dbbd32-2962-9fc3-40b1-67e864f21cd2</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table></div>"
},
"manufacturer" : [
{
"reference" : "Organization/23dbbd32-2962-9fc3-40b1-67e864f21cd2"
}
],
"name" : [
// Organization/substance-manufacturer
{
"name" : "Stelbatolol"
}
]
}
},
{
"fullUrl" : "urn:uuid:23dbbd32-2962-9fc3-40b1-67e864f21cd2",
"resource" : {
"resourceType" : "Organization",
"id" : "23dbbd32-2962-9fc3-40b1-67e864f21cd2",
"text" : // substance-manufacturer
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_23dbbd32-2962-9fc3-40b1-67e864f21cd2\"> </a><p><b>Generated Narrative: Organization</b><a name=\"23dbbd32-2962-9fc3-40b1-67e864f21cd2\"> </a><a name=\"hc23dbbd32-2962-9fc3-40b1-67e864f21cd2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization "23dbbd32-2962-9fc3-40b1-67e864f21cd2" </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
},
"identifier" : [
{
"system" : "urn:oid:2.16.840.1.113883.4.82",
"value" : "3003040516"
}
],
"active" : true,
"type" : [
// FDA establishment identifier
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
"code" : "drug-substance-manufacture",
"display" : "Drug Substance Manufacture"
}
]
}
],
"name" : "AAA Molybdenum Products, Inc.",
"contact" : [
{
"address" : {
"line" : [
"7233 W 116th Pl",
"Ste C"
],
"city" : "Broomfield",
"state" : "Colorado",
"postalCode" : "80020",
"country" : "USA"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b08",
"resource" : {
"resourceType" : "Organization",
"id" : "378fbe5f-5926-3a5c-4c64-5428df877b08",
"text" : // testing lab
// 378fbe5f-5926-3a5c-4c64-5428df877b08
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a><p><b>Generated Narrative: Organization</b><a name=\"378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a><a name=\"hc378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization "378fbe5f-5926-3a5c-4c64-5428df877b08" </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3007270600</p><p><b>active</b>: true</p><p><b>type</b>: Analytical Testing - Release <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#analytical-testing-release)</span></p><p><b>name</b>: Testing Lab</p></div>"
},
"identifier" : [
{
"system" : "urn:oid:2.16.840.1.113883.4.82",
"value" : "3007270600"
}
],
"active" : true,
"type" : [
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
"code" : "analytical-testing-release",
"display" : "Analytical Testing - Release"
}
]
}
],
"name" : "Testing Lab"
}
},
{
"fullUrl" : "urn:uuid:246e9583-6253-6cc7-9c12-3b624f3308c1",
"resource" : {
"resourceType" : "PlanDefinition",
"id" : "246e9583-6253-6cc7-9c12-3b624f3308c1",
"meta" : // <id value="manufacturingProcess"/>
// id value="plandefinition-mnf-process-dxpq-ex1"/
// plandefinition-drug-pq-ex4-mnf-process
{
"profile" : [
🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PlanDefinition-drug-pq"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_246e9583-6253-6cc7-9c12-3b624f3308c1\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"246e9583-6253-6cc7-9c12-3b624f3308c1\"> </a><a name=\"hc246e9583-6253-6cc7-9c12-3b624f3308c1\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition "246e9583-6253-6cc7-9c12-3b624f3308c1" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-PlanDefinition-drug-pq.html\">PlanDefinition - Drug PQ</a></p></div><p><b>Extension - History of Process PQ</b>: Process has no history recorded yet</p><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/246e9583-6253-6cc7-9c12-3b624f3308c1</code></p><p><b>title</b>: Process 1.0</p><p><b>type</b>: Manufacturing Process <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#1244566)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p></div>"
},
"extension" : [
// added for IG, to differentiate from PlanDefinition-drug-specification-dxpq
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-history-of-process-pq",
"valueMarkdown" : "Process has no history recorded yet"
}
],
"url" : "http://example-server.com/fhir/PlanDefinition/246e9583-6253-6cc7-9c12-3b624f3308c1",
"title" : "Process 1.0",
"type" : // http://example-server.com/fhir/PlanDefinition/246e9583-6253-6cc7-9c12-3b624f3308c1
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
"code" : "1244566",
"display" : "Manufacturing Process"
}
]
},
"status" : "active",
"subjectReference" : {
"reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
}
}
}
]
}
IG © HL7 International / Biomedical Research and Regulation. Package hl7.fhir.uv.pharm-quality#1.0.0 based on FHIR 5.0.0. Generated 2024-05-08
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