Standardized Medication Profile (SMP) FHIR IG, published by HL7 International / Pharmacy. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/smp-ig/ and changes regularly. See the Directory of published versions

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: betsysmith-johnson01-di01-Drug-druginteraction0 - XML Representation

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<DetectedIssue xmlns="http://hl7.org/fhir">
  <id value="betsysmith-johnson01-di01-Drug-druginteraction0"/>
  <meta>
    <versionId value="1"/>
    <lastUpdated value="2026-01-07T10:51:49.9947894+00:00"/>
    <source value="#fIOfmNQFLI3AB7nY"/>
    <profile
             value="http://hl7.org/fhir/us/smp/StructureDefinition/smp-medication-action-plan-detected-issue"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: DetectedIssue betsysmith-johnson01-di01-Drug-druginteraction0</b></p><a name="betsysmith-johnson01-di01-Drug-druginteraction0"> </a><a name="hcbetsysmith-johnson01-di01-Drug-druginteraction0"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">version: 1; Last updated: 2026-01-07 10:51:49+0000; </p><p style="margin-bottom: 0px">Information Source: #fIOfmNQFLI3AB7nY</p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-smp-medication-action-plan-detected-issue.html">Standardized Medication Profile - Medication Action Plan Detected Issue</a></p></div><p><b>status</b>: Preliminary</p><p><b>code</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/v3-ActCode DRG}">Drug Interaction Alert</span></p><p><b>severity</b>: High</p><p><b>patient</b>: <a href="Patient-patient-betsysmith-johnson01.html">Smith-Johnson, Betsy Female, DoB: 1950-11-15 ( http://hl7.org/fhir/sid/us-medicare#United States Medicare Number#1PA3D58WH16)</a></p><p><b>identified</b>: 2026-01-07 10:51:49+0000</p><p><b>author</b>: <a href="Practitioner-Practitioner-KevinJames.html">Practitioner Kevin James</a></p><p><b>implicated</b>: </p><ul><li><a href="MedicationStatement-bsj1-smp-medstmt-clopidogrel-1-11.html">Clopidogrel Bisulfate Oral Tablet 75 MG (Clopidogrel Bisulfate)</a></li><li><a href="MedicationStatement-bsj1-smp-medstmt-sertraline-1-8.html">Sertraline HCl Oral Tablet 25 MG (Sertraline HCl)</a></li></ul><p><b>detail</b>: Selective serotonin reuptake inhibitors (eg, Sertraline HCl Oral Tablet 25 MG) may enhance the antiplatelet effect and increase the bleeding risk of purinergic signaling receptor Y12 (P2Y12) inhibitors such as Clopidogrel Bisulfate Oral Tablet 75 MG</p><h3>Mitigations</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Action</b></td><td><b>Date</b></td><td><b>Author</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://terminology.hl7.org/CodeSystem/v3-ActCode 13}">drug drug interaction, change medicine dose</span></td><td>2026-01-07 10:51:49+0000</td><td><a href="Practitioner-Practitioner-KevinJames.html">Practitioner Kevin James</a></td></tr></table></div>
  </text>
  <status value="preliminary"/>
  <code>
    <coding>
      <system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/>
      <code value="DRG"/>
      <display value="Drug Interaction Alert"/>
    </coding>
  </code>
  <severity value="high"/>
  <patient>🔗 
    <reference value="Patient/patient-betsysmith-johnson01"/>
  </patient>
  <identifiedDateTime value="2026-01-07T10:51:49.9953967+00:00"/>
  <author>🔗 
    <reference value="Practitioner/Practitioner-KevinJames"/>
  </author>
  <implicated>🔗 
    <reference value="MedicationStatement/bsj1-smp-medstmt-clopidogrel-1-11"/>
    <display
             value="Clopidogrel Bisulfate Oral Tablet 75 MG (Clopidogrel Bisulfate)"/>
  </implicated>
  <implicated>🔗 
    <reference value="MedicationStatement/bsj1-smp-medstmt-sertraline-1-8"/>
    <display value="Sertraline HCl Oral Tablet 25 MG (Sertraline HCl)"/>
  </implicated>
  <detail
          value="Selective serotonin reuptake inhibitors (eg, Sertraline HCl Oral Tablet 25 MG) may enhance the antiplatelet effect and increase the bleeding risk of purinergic signaling receptor Y12 (P2Y12) inhibitors such as Clopidogrel Bisulfate Oral Tablet 75 MG"/>
  <mitigation>
    <action>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/>
        <code value="13"/>
        <display value="Stopped Concurrent Therapy"/>
      </coding>
      <text value="drug drug interaction, change medicine dose"/>
    </action>
    <date value="2026-01-07T10:51:49.9959238+00:00"/>
    <author>🔗 
      <reference value="Practitioner/Practitioner-KevinJames"/>
    </author>
  </mitigation>
</DetectedIssue>