Standardized Medication Profile (SMP) FHIR IG, published by HL7 International / Pharmacy. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/smp-ig/ and changes regularly. See the Directory of published versions

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: betsysmith-johnson01-di01-Drug-druginteraction0 - JSON Representation

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{
  "resourceType" : "DetectedIssue",
  "id" : "betsysmith-johnson01-di01-Drug-druginteraction0",
  "meta" : {
    "versionId" : "1",
    "lastUpdated" : "2026-01-07T10:51:49.9947894+00:00",
    "source" : "#fIOfmNQFLI3AB7nY",
    "profile" : [
      🔗 "http://hl7.org/fhir/us/smp/StructureDefinition/smp-medication-action-plan-detected-issue"
    ]
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: DetectedIssue betsysmith-johnson01-di01-Drug-druginteraction0</b></p><a name=\"betsysmith-johnson01-di01-Drug-druginteraction0\"> </a><a name=\"hcbetsysmith-johnson01-di01-Drug-druginteraction0\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 1; Last updated: 2026-01-07 10:51:49+0000; </p><p style=\"margin-bottom: 0px\">Information Source: #fIOfmNQFLI3AB7nY</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-smp-medication-action-plan-detected-issue.html\">Standardized Medication Profile - Medication Action Plan Detected Issue</a></p></div><p><b>status</b>: Preliminary</p><p><b>code</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-ActCode DRG}\">Drug Interaction Alert</span></p><p><b>severity</b>: High</p><p><b>patient</b>: <a href=\"Patient-patient-betsysmith-johnson01.html\">Smith-Johnson, Betsy Female, DoB: 1950-11-15 ( http://hl7.org/fhir/sid/us-medicare#United States Medicare Number#1PA3D58WH16)</a></p><p><b>identified</b>: 2026-01-07 10:51:49+0000</p><p><b>author</b>: <a href=\"Practitioner-Practitioner-KevinJames.html\">Practitioner Kevin James</a></p><p><b>implicated</b>: </p><ul><li><a href=\"MedicationStatement-bsj1-smp-medstmt-clopidogrel-1-11.html\">Clopidogrel Bisulfate Oral Tablet 75 MG (Clopidogrel Bisulfate)</a></li><li><a href=\"MedicationStatement-bsj1-smp-medstmt-sertraline-1-8.html\">Sertraline HCl Oral Tablet 25 MG (Sertraline HCl)</a></li></ul><p><b>detail</b>: Selective serotonin reuptake inhibitors (eg, Sertraline HCl Oral Tablet 25 MG) may enhance the antiplatelet effect and increase the bleeding risk of purinergic signaling receptor Y12 (P2Y12) inhibitors such as Clopidogrel Bisulfate Oral Tablet 75 MG</p><h3>Mitigations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Action</b></td><td><b>Date</b></td><td><b>Author</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-ActCode 13}\">drug drug interaction, change medicine dose</span></td><td>2026-01-07 10:51:49+0000</td><td><a href=\"Practitioner-Practitioner-KevinJames.html\">Practitioner Kevin James</a></td></tr></table></div>"
  },
  "status" : "preliminary",
  "code" : {
    "coding" : [
      {
        "system" : "http://terminology.hl7.org/CodeSystem/v3-ActCode",
        "code" : "DRG",
        "display" : "Drug Interaction Alert"
      }
    ]
  },
  "severity" : "high",
  "patient" : {
    🔗 "reference" : "Patient/patient-betsysmith-johnson01"
  },
  "identifiedDateTime" : "2026-01-07T10:51:49.9953967+00:00",
  "author" : {
    🔗 "reference" : "Practitioner/Practitioner-KevinJames"
  },
  "implicated" : [
    {
      🔗 "reference" : "MedicationStatement/bsj1-smp-medstmt-clopidogrel-1-11",
      "display" : "Clopidogrel Bisulfate Oral Tablet 75 MG (Clopidogrel Bisulfate)"
    },
    {
      🔗 "reference" : "MedicationStatement/bsj1-smp-medstmt-sertraline-1-8",
      "display" : "Sertraline HCl Oral Tablet 25 MG (Sertraline HCl)"
    }
  ],
  "detail" : "Selective serotonin reuptake inhibitors (eg, Sertraline HCl Oral Tablet 25 MG) may enhance the antiplatelet effect and increase the bleeding risk of purinergic signaling receptor Y12 (P2Y12) inhibitors such as Clopidogrel Bisulfate Oral Tablet 75 MG",
  "mitigation" : [
    {
      "action" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/v3-ActCode",
            "code" : "13",
            "display" : "Stopped Concurrent Therapy"
          }
        ],
        "text" : "drug drug interaction, change medicine dose"
      },
      "date" : "2026-01-07T10:51:49.9959238+00:00",
      "author" : {
        🔗 "reference" : "Practitioner/Practitioner-KevinJames"
      }
    }
  ]
}