Code | Display | Definition |
1.1 |
RT to a vol exposing the thyroid gland |
RT to a vol exposing the thyroid gland |
1.2 |
TBI |
TBI |
1.3 |
MIBG therapy (I-131 MIBG therapy) |
MIBG therapy (I-131 MIBG therapy) |
2.1 |
RT >= 10 Gy to a vol exposing the breasts |
RT >= 10 Gy to a vol exposing the breasts |
2.2 |
OR upper abdominal field radiation that can extend above the diaphragm likely exposing breast tissue at a young age |
OR upper abdominal field radiation that can extend above the diaphragm likely exposing breast tissue at a young age |
3.1 |
RT >= 35 Gy to a vol exposing the heart |
RT >= 35 Gy to a vol exposing the heart |
3.2 |
Anthracyclines (doxorubicin isotoxic equivalents)>= 250 mg/m2 |
Anthracyclines (doxorubicin isotoxic equivalents)>= 250 mg/m2 |
3.3 |
RT >= 15 Gy to a vol exposing the heart AND Anthracyclines (doxorubicin isotoxic equivalents)>= 100 mg/m2 |
RT >= 15 Gy to a vol exposing the heart AND Anthracyclines (doxorubicin isotoxic equivalents)>= 100 mg/m2 |
4.1 |
Alkylating agents |
Alkylating agents |
4.2 |
RT to a vol exposing the testes |
RT to a vol exposing the testes |
4.3 |
Including TBI |
Including TBI |
5.1 |
RT >=12 Gy to a vol exposing the testicles |
RT >=12 Gy to a vol exposing the testicles |
6.3 |
Surgery to the spinal cord, sympathetic nerves or pelvis |
Surgery to the spinal cord, sympathetic nerves or pelvis |
6.4 |
Hypogonadal |
Hypogonadal |
7.2 |
RT to a vol exposing the ovaries |
RT to a vol exposing the ovaries |
8.1 |
RT >= 30 Gy to a vol exposing the head or the brain |
RT >= 30 Gy to a vol exposing the head or the brain |
8.2 |
Cisplatin (with or without carboplatin > 1500 mg/m2) |
Cisplatin (with or without carboplatin > 1500 mg/m2) |
9.1 |
RT to a vol exposing the pancreas |
RT to a vol exposing the pancreas |
10.2 |
HSCT |
HSCT |
11.1 |
RT to a volume exposing the hypothalamus or pituatary gland |
RT to a volume exposing the hypothalamus or pituatary gland |
11.3 |
Hypothalamic or pituitary tumour |
Hypothalamic or pituitary tumour |
11.4 |
Neurosurgery of the hypothalamus or pituitary gland |
Neurosurgery of the hypothalamus or pituitary gland |
12.1 |
RT to a vol exposing the kidneys, heart and associated large vessels |
RT to a vol exposing the kidneys, heart and associated large vessels |
12.3 |
Nephrectomy |
Nephrectomy |
12.4 |
Ifosfamide |
Ifosfamide |
12.5 |
Platinium based chemotherapy |
Platinium based chemotherapy |
12.6 |
Nitrosureas |
Nitrosureas |
12.7 |
Immunosuppressives treatment and prolonged steroids as anticancer treatment (at least 4 weeks, continuously) |
Immunosuppressives treatment and prolonged steroids as anticancer treatment (at least 4 weeks, continuously) |
13.1 |
Cranial and/or spinal RT |
Cranial and/or spinal RT |
13.3 |
Methotrexate |
Methotrexate |
13.4 |
Gonadal failure |
Gonadal failure |
13.5 |
Growth hormone deficiency |
Growth hormone deficiency |
13.6 |
Prolonged (at least 4 weeks, continuously) corticosteroids as anti-cancer treatment |
Prolonged (at least 4 weeks, continuously) corticosteroids as anti-cancer treatment |
13.7 |
HSCT, especially with an history of GVHD |
HSCT, especially with an history of GVHD |
14.3 |
High dose RT |
High dose RT |
15.1 |
Radiotherapy to a vol exposing the HP region >= 30 Gy |
Radiotherapy to a vol exposing the HP region >= 30 Gy |
15.2 |
Surgery near or within the HP region |
Surgery near or within the HP region |
15.3 |
CNS tumours near or within the HP region |
CNS tumours near or within the HP region |
16.1 |
Radiotherapy to a vol exposing the HP region< 30 Gy |
Radiotherapy to a vol exposing the HP region< 30 Gy |
16.2 |
Hydrocephalus or cerebrospinal fluid shunt(Risk factor for GHD) |
Hydrocephalus or cerebrospinal fluid shunt(Risk factor for GHD) |
17.1 |
Radiotherapy to a vol exposing the HP region |
Radiotherapy to a vol exposing the HP region |
17.5 |
hydrocephalus or cerebrospinal fluid shunt |
hydrocephalus or cerebrospinal fluid shunt |
19.3 |
Radioiodine therapy (I-131 ablation therapy) |
Radioiodine therapy (I-131 ablation therapy) |
19.5 |
Allogenic HSCT |
Allogenic HSCT |
19.6 |
Total thyroidectomy |
Total thyroidectomy |
20.1 |
RT to a vol exposing the head, brain or neck |
RT to a vol exposing the head, brain or neck |
21.1 |
History of a central nervous system tumor |
History of a central nervous system tumor |
21.2 |
RT to a vol exposing the brain ANY DOSE |
RT to a vol exposing the brain ANY DOSE |
21.4 |
Brain surgery |
Brain surgery |
21.5 |
High dose cytarabine IV (intravenous) |
High dose cytarabine IV (intravenous) |
21.6 |
High dose MTX IV |
High dose MTX IV |
21.7 |
Any Chemotherapy IT (intrathecal) |
Any Chemotherapy IT (intrathecal) |
22.1 |
Vinca-Alkaloids |
Vinca-Alkaloids |
22.2 |
Cisplatin or carboplatin |
Cisplatin or carboplatin |
23.1 |
RT to a vol exposing the lens |
RT to a vol exposing the lens |
24.1 |
RT to a vol exposing the eye and orbit |
RT to a vol exposing the eye and orbit |
25.1 |
RT to a vol exposing the craniofacial area, especially after high doses and at a young age |
RT to a vol exposing the craniofacial area, especially after high doses and at a young age |
25.3 |
Surgery to the face, especially at a young age |
Surgery to the face, especially at a young age |
26.1 |
Surgery of the spine |
Surgery of the spine |
26.2 |
Surgery of the chest (Does not include CVC pose) |
Surgery of the chest (Does not include CVC pose) |
26.3 |
RT to a vol exposing the spine |
RT to a vol exposing the spine |
26.4 |
Spinal or paraspinal malignancies |
Spinal or paraspinal malignancies |
27.1 |
Cyclophosphamide |
Cyclophosphamide |
27.3 |
RT to a vol exposing the bladder |
RT to a vol exposing the bladder |
27.5 |
Cystectomy |
Cystectomy |
27.6 |
Hysterectomy |
Hysterectomy |
27.7 |
Pelvic surgery |
Pelvic surgery |
27.8 |
Spinal cord surgery |
Spinal cord surgery |
28.1 |
RT to a vol exposing the uterus only female |
RT to a vol exposing the uterus only female |
29.1 |
RT to a vol exposing the oral cavity or salivary glands |
RT to a vol exposing the oral cavity or salivary glands |
29.4 |
Chemotherapy |
Chemotherapy |
30.1 |
RT to a vol exposing the gastro-intestinal tract |
RT to a vol exposing the gastro-intestinal tract |
30.3 |
Oesophageal surgery |
Oesophageal surgery |
30.4 |
Abdominal surgery |
Abdominal surgery |
30.5 |
With a history of chronic GVHD |
With a history of chronic GVHD |
31.1 |
Anthracyclines (doxorubicin isotoxic equivalents) <100 mg/m2 |
Anthracyclines (doxorubicin isotoxic equivalents) <100 mg/m2 |
32.1 |
RT to a vol exposing the lungs |
RT to a vol exposing the lungs |
32.3 |
Bleomycin |
Bleomycin |
32.4 |
Busulfan |
Busulfan |
32.5 |
BCNU Carmustine |
BCNU Carmustine |
32.6 |
CCNU Lomustine |
CCNU Lomustine |
32.7 |
Thoracic surgery |
Thoracic surgery |
33.1 |
Cisplatin Any dose |
Cisplatin Any dose |
33.2 |
Ifosfamide Any dose |
Ifosfamide Any dose |
33.3 |
Carboplatin Any dose |
Carboplatin Any dose |
34.1 |
RT to a volume exposing the liver |
RT to a volume exposing the liver |
34.10 |
Chronic GVHD |
Chronic GVHD |
34.11 |
Liver surgery |
Liver surgery |
34.3 |
HSCT (irrespective of GVHD) |
HSCT (irrespective of GVHD) |
34.5 |
Mercaptopurine Thioguanine |
Mercaptopurine Thioguanine |
34.6 |
Dactinomycin |
Dactinomycin |
34.8 |
Chronic viral hepatitis |
Chronic viral hepatitis |
34.9 |
Sinusoidal obstruction syndrome |
Sinusoidal obstruction syndrome |
35.1 |
HSCT (irrespective of GVHD) |
HSCT (irrespective of GVHD) |
35.2 |
Multiple red blood cell transfusions |
Multiple red blood cell transfusions |
36.1 |
Splenectomy |
Splenectomy |
36.2 |
RT >= 10 Gy to a vol exposing the spleen |
RT >= 10 Gy to a vol exposing the spleen |
36.3 |
Allogenic HSCT (with or without TBI) |
Allogenic HSCT (with or without TBI) |
36.4 |
Autologus HSCT conditioned with TBI |
Autologus HSCT conditioned with TBI |
37.1 |
Hereditary cancer sd |
Hereditary cancer sd |
38.1 |
Any RT including TBI (predominantly in the RT field) |
Any RT including TBI (predominantly in the RT field) |
38.2 |
HSCT Especially with a history of skin GvHD |
HSCT Especially with a history of skin GvHD |
39.1 |
RT to a vol exposing the colon and rectum |
RT to a vol exposing the colon and rectum |
40.1 |
RT to a vol exposing the oral cavity |
RT to a vol exposing the oral cavity |
41.2 |
Anthracyclines and/or Mitoxantrone |
Anthracyclines and/or Mitoxantrone |
41.3 |
Epipodophyllotoxins or autologous |
Epipodophyllotoxins or autologous |
41.4 |
Autologous haematopoietic stem cell transplant |
Autologous haematopoietic stem cell transplant |
42.1 |
Ciclofosfamide, Ifosfamide (particularly if they have a history of severe hemorrhagic cystitis) |
Ciclofosfamide, Ifosfamide (particularly if they have a history of severe hemorrhagic cystitis) |
45.1 |
RT to a vol exposing the head or brain |
RT to a vol exposing the head or brain |
46.1 |
RT between 15 and 35 Gy to a vol exposing the heart |
RT between 15 and 35 Gy to a vol exposing the heart |
46.2 |
Anthracyclines (doxorubicin isotoxic equivalents) between 100 and 250 mg/m2 |
Anthracyclines (doxorubicin isotoxic equivalents) between 100 and 250 mg/m2 |
47.1 |
RT to a vol exposing the kidney or urinary tract |
RT to a vol exposing the kidney or urinary tract |