HL7 Europe Medication Prescription and Dispense, published by HL7 Europe. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/mpd/ and changes regularly. See the Directory of published versions

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• Detailed Descriptions
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Resource Profile: Medication: MPD

This profile defines how to represent MedicationRequest in HL7 FHIR for the purpose of this guide.

Usages:

• Refer to this Profile: Medication: MPD, MedicationDispense: MPD and MedicationRequest: MPD
• Examples for this Profile: Medication/01A-Cefuroxime1500GenericExplicit, Medication/01B-Cefuroxime1500GenericConcept, Medication/01C-Cefuroxime1500Branded, Medication/01D-Cefuroxime750Branded... Show 6 more, Medication/02A-ClotrimazoleCanifugCremolum, Medication/02A1-CanifugCremolumCreamItem, Medication/02A2-CanifugCremolumPessaryItem, Medication/03B-VitaminBComplexBranded, Medication/04A-FirmagonBranded and Medication/05A-Tilidin-Branded

You can also check for usages in the FHIR IG Statistics

Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

• Key Elements Table
• Differential Table
• Snapshot Table
• Statistics/References
• All

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Medication		0..*	Medication	Definition of a Medication
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:productName		0..1	string	Name of the medicinal product. Names of different types (full name, short name, etc) and in different languages can be provided if relevant. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification		0..*	CodeableConcept	Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem		0..1	Quantity	Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic		0..*	(Complex)	Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation		0..1	CodeableConcept	Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType		0..1	CodeableConcept	Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device		0..*	(Complex)	Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
Slices for extension		2..*	Extension	Extension Slice: Unordered, Open by value:url
extension:device		1..1	Extension	Extension
extension		0..0
url		1..1	uri	"device"
value[x]		0..1	CodeableConcept	Value of extension Binding: eHDSI Package (example)
extension:quantity		1..1	Extension	Number of defined devices in te package
extension		0..0
url		1..1	uri	"quantity"
url		1..1	uri	"https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device"
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	Identifier for the medicinal product, its generic representation, or packaged product.
code	Σ	0..1	CodeableConcept	A terminology-based code for the product Binding: SNOMEDCTMedicationCodes (example): A coded concept that defines the type of a medication.
status	?!Σ	0..1	code	active | inactive | entered-in-error Binding: Medication Status Codes (required): A coded concept defining if the medication is in active use.
form		0..1	CodeableConcept	powder | tablets | capsule + Binding: eHDSI Dose Form (example)
ingredient		0..*	BackboneElement	Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Slices for item[x]		1..1		The actual ingredient or content Slice: Unordered, Closed by type:$this
itemCodeableConcept			CodeableConcept
itemReference			Reference(Substance | Medication)
item[x]:itemReference		0..1	Reference(Medication: MPD)	The actual ingredient or content
item[x]:itemCodeableConcept		0..1	CodeableConcept	The actual ingredient or content Binding: Medicine Active Substances - IPS (example) Additional Bindings Purpose eHDSI Substance candidate
strength		0..1	Ratio	Amount of substance in product (presentation or concentration strength)
Slices for extension				Content/Rules for all slices
extension:basisOfStrengthSubstance		0..1	CodeableConcept	Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
Medication.extension:device.extension:device.value[x]	example	eHDSIPackage http://terminology.ehdsi.eu/ValueSet/eHDSIPackage From http://tx.hl7europe.eu/r4
Medication.code	example	SNOMEDCTMedicationCodes http://hl7.org/fhir/ValueSet/medication-codes From the FHIR Standard
Medication.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-status|4.0.1 From the FHIR Standard
Medication.form	example	eHDSIDoseForm http://terminology.ehdsi.eu/ValueSet/eHDSIDoseForm From http://tx.hl7europe.eu/r4
Medication.ingredient.item[x]:itemCodeableConcept	example	MedicineActiveSubstancesUvIps http://hl7.org/fhir/uv/ips/ValueSet/medicine-active-substances-uv-ips

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	Medication	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Medication	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Medication	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Medication	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Medication	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

This structure is derived from Medication

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Medication		0..*	Medication	Definition of a Medication
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:productName		0..1	string	Name of the medicinal product. Names of different types (full name, short name, etc) and in different languages can be provided if relevant. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification		0..*	CodeableConcept	Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem		0..1	Quantity	Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic		0..*	(Complex)	Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation		0..1	CodeableConcept	Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType		0..1	CodeableConcept	Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device		0..*	(Complex)	Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
Slices for extension				Content/Rules for all slices
extension:device		1..1	Extension	Extension
value[x]		0..1	CodeableConcept	Value of extension Binding: eHDSI Package (example)
identifier		0..*	Identifier	Identifier for the medicinal product, its generic representation, or packaged product.
code		0..1	CodeableConcept	A terminology-based code for the product
form		0..1	CodeableConcept	powder | tablets | capsule + Binding: eHDSI Dose Form (example)
ingredient		0..*	BackboneElement	Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
Slices for item[x]		1..1	CodeableConcept, Reference(Substance | Medication)	The actual ingredient or content Slice: Unordered, Open by type:$this
item[x]:itemReference		0..1	Reference(Medication: MPD)	The actual ingredient or content
item[x]:itemCodeableConcept		0..1	CodeableConcept	The actual ingredient or content Binding: Medicine Active Substances - IPS (example) Additional Bindings Purpose eHDSI Substance candidate
strength		0..1	Ratio	Amount of substance in product (presentation or concentration strength)
Slices for extension				Content/Rules for all slices
extension:basisOfStrengthSubstance		0..1	CodeableConcept	Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
Medication.extension:device.extension:device.value[x]	example	eHDSIPackage http://terminology.ehdsi.eu/ValueSet/eHDSIPackage From http://tx.hl7europe.eu/r4
Medication.form	example	eHDSIDoseForm http://terminology.ehdsi.eu/ValueSet/eHDSIDoseForm From http://tx.hl7europe.eu/r4
Medication.ingredient.item[x]:itemCodeableConcept	example	MedicineActiveSubstancesUvIps http://hl7.org/fhir/uv/ips/ValueSet/medicine-active-substances-uv-ips

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Medication		0..*	Medication	Definition of a Medication
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:productName		0..1	string	Name of the medicinal product. Names of different types (full name, short name, etc) and in different languages can be provided if relevant. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification		0..*	CodeableConcept	Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem		0..1	Quantity	Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic		0..*	(Complex)	Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation		0..1	CodeableConcept	Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType		0..1	CodeableConcept	Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device		0..*	(Complex)	Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
id		0..1	string	Unique id for inter-element referencing
Slices for extension		2..*	Extension	Extension Slice: Unordered, Open by value:url
extension:device		1..1	Extension	Extension
id		0..1	string	Unique id for inter-element referencing
extension		0..0
url		1..1	uri	"device"
value[x]		0..1	CodeableConcept	Value of extension Binding: eHDSI Package (example)
extension:quantity		1..1	Extension	Number of defined devices in te package
id		0..1	string	Unique id for inter-element referencing
extension		0..0
url		1..1	uri	"quantity"
value[x]		0..1	Quantity	Value of extension
url		1..1	uri	"https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device"
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	Identifier for the medicinal product, its generic representation, or packaged product.
code	Σ	0..1	CodeableConcept	A terminology-based code for the product Binding: SNOMEDCTMedicationCodes (example): A coded concept that defines the type of a medication.
status	?!Σ	0..1	code	active | inactive | entered-in-error Binding: Medication Status Codes (required): A coded concept defining if the medication is in active use.
manufacturer	Σ	0..1	Reference(Organization)	Manufacturer of the item
form		0..1	CodeableConcept	powder | tablets | capsule + Binding: eHDSI Dose Form (example)
amount	Σ	0..1	Ratio	Amount of drug in package
ingredient		0..*	BackboneElement	Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Slices for item[x]		1..1		The actual ingredient or content Slice: Unordered, Closed by type:$this
itemCodeableConcept			CodeableConcept
itemReference			Reference(Substance | Medication)
item[x]:itemReference		0..1	Reference(Medication: MPD)	The actual ingredient or content
item[x]:itemCodeableConcept		0..1	CodeableConcept	The actual ingredient or content Binding: Medicine Active Substances - IPS (example) Additional Bindings Purpose eHDSI Substance candidate
isActive		0..1	boolean	Active ingredient indicator
strength		0..1	Ratio	Amount of substance in product (presentation or concentration strength)
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
extension:basisOfStrengthSubstance		0..1	CodeableConcept	Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
numerator	Σ	0..1	Quantity	Numerator value
denominator	Σ	0..1	Quantity	Denominator value
batch		0..1	BackboneElement	Details about packaged medications
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
lotNumber		0..1	string	Identifier assigned to batch
expirationDate		0..1	dateTime	When batch will expire
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
Medication.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages From the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
Medication.extension:device.extension:device.value[x]	example	eHDSIPackage http://terminology.ehdsi.eu/ValueSet/eHDSIPackage From http://tx.hl7europe.eu/r4
Medication.code	example	SNOMEDCTMedicationCodes http://hl7.org/fhir/ValueSet/medication-codes From the FHIR Standard
Medication.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-status|4.0.1 From the FHIR Standard
Medication.form	example	eHDSIDoseForm http://terminology.ehdsi.eu/ValueSet/eHDSIDoseForm From http://tx.hl7europe.eu/r4
Medication.ingredient.item[x]:itemCodeableConcept	example	MedicineActiveSubstancesUvIps http://hl7.org/fhir/uv/ips/ValueSet/medicine-active-substances-uv-ips

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	Medication	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Medication	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Medication	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Medication	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Medication	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

This structure is derived from Medication

Summary

Structures

This structure refers to these other structures:

• Medication: MPD (http://hl7.eu/fhir/mpd/StructureDefinition/Medication-eu-mpd)

Extensions

This structure refers to these extensions:

• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation
• http://hl7.eu/fhir/StructureDefinition/medication-package-type
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of Medication.ingredient.item[x]

Key Elements View

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Medication		0..*	Medication	Definition of a Medication
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:productName		0..1	string	Name of the medicinal product. Names of different types (full name, short name, etc) and in different languages can be provided if relevant. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification		0..*	CodeableConcept	Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem		0..1	Quantity	Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic		0..*	(Complex)	Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation		0..1	CodeableConcept	Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType		0..1	CodeableConcept	Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device		0..*	(Complex)	Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
Slices for extension		2..*	Extension	Extension Slice: Unordered, Open by value:url
extension:device		1..1	Extension	Extension
extension		0..0
url		1..1	uri	"device"
value[x]		0..1	CodeableConcept	Value of extension Binding: eHDSI Package (example)
extension:quantity		1..1	Extension	Number of defined devices in te package
extension		0..0
url		1..1	uri	"quantity"
url		1..1	uri	"https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device"
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	Identifier for the medicinal product, its generic representation, or packaged product.
code	Σ	0..1	CodeableConcept	A terminology-based code for the product Binding: SNOMEDCTMedicationCodes (example): A coded concept that defines the type of a medication.
status	?!Σ	0..1	code	active | inactive | entered-in-error Binding: Medication Status Codes (required): A coded concept defining if the medication is in active use.
form		0..1	CodeableConcept	powder | tablets | capsule + Binding: eHDSI Dose Form (example)
ingredient		0..*	BackboneElement	Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Slices for item[x]		1..1		The actual ingredient or content Slice: Unordered, Closed by type:$this
itemCodeableConcept			CodeableConcept
itemReference			Reference(Substance | Medication)
item[x]:itemReference		0..1	Reference(Medication: MPD)	The actual ingredient or content
item[x]:itemCodeableConcept		0..1	CodeableConcept	The actual ingredient or content Binding: Medicine Active Substances - IPS (example) Additional Bindings Purpose eHDSI Substance candidate
strength		0..1	Ratio	Amount of substance in product (presentation or concentration strength)
Slices for extension				Content/Rules for all slices
extension:basisOfStrengthSubstance		0..1	CodeableConcept	Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
Medication.extension:device.extension:device.value[x]	example	eHDSIPackage http://terminology.ehdsi.eu/ValueSet/eHDSIPackage From http://tx.hl7europe.eu/r4
Medication.code	example	SNOMEDCTMedicationCodes http://hl7.org/fhir/ValueSet/medication-codes From the FHIR Standard
Medication.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-status|4.0.1 From the FHIR Standard
Medication.form	example	eHDSIDoseForm http://terminology.ehdsi.eu/ValueSet/eHDSIDoseForm From http://tx.hl7europe.eu/r4
Medication.ingredient.item[x]:itemCodeableConcept	example	MedicineActiveSubstancesUvIps http://hl7.org/fhir/uv/ips/ValueSet/medicine-active-substances-uv-ips

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	Medication	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Medication	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Medication	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Medication	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Medication	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Differential View

This structure is derived from Medication

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Medication		0..*	Medication	Definition of a Medication
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:productName		0..1	string	Name of the medicinal product. Names of different types (full name, short name, etc) and in different languages can be provided if relevant. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification		0..*	CodeableConcept	Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem		0..1	Quantity	Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic		0..*	(Complex)	Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation		0..1	CodeableConcept	Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType		0..1	CodeableConcept	Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device		0..*	(Complex)	Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
Slices for extension				Content/Rules for all slices
extension:device		1..1	Extension	Extension
value[x]		0..1	CodeableConcept	Value of extension Binding: eHDSI Package (example)
identifier		0..*	Identifier	Identifier for the medicinal product, its generic representation, or packaged product.
code		0..1	CodeableConcept	A terminology-based code for the product
form		0..1	CodeableConcept	powder | tablets | capsule + Binding: eHDSI Dose Form (example)
ingredient		0..*	BackboneElement	Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
Slices for item[x]		1..1	CodeableConcept, Reference(Substance | Medication)	The actual ingredient or content Slice: Unordered, Open by type:$this
item[x]:itemReference		0..1	Reference(Medication: MPD)	The actual ingredient or content
item[x]:itemCodeableConcept		0..1	CodeableConcept	The actual ingredient or content Binding: Medicine Active Substances - IPS (example) Additional Bindings Purpose eHDSI Substance candidate
strength		0..1	Ratio	Amount of substance in product (presentation or concentration strength)
Slices for extension				Content/Rules for all slices
extension:basisOfStrengthSubstance		0..1	CodeableConcept	Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
Medication.extension:device.extension:device.value[x]	example	eHDSIPackage http://terminology.ehdsi.eu/ValueSet/eHDSIPackage From http://tx.hl7europe.eu/r4
Medication.form	example	eHDSIDoseForm http://terminology.ehdsi.eu/ValueSet/eHDSIDoseForm From http://tx.hl7europe.eu/r4
Medication.ingredient.item[x]:itemCodeableConcept	example	MedicineActiveSubstancesUvIps http://hl7.org/fhir/uv/ips/ValueSet/medicine-active-substances-uv-ips

Snapshot View

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Medication		0..*	Medication	Definition of a Medication
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:productName		0..1	string	Name of the medicinal product. Names of different types (full name, short name, etc) and in different languages can be provided if relevant. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
extension:classification		0..*	CodeableConcept	Classifications of the product, e.g ATC, narcotic/psychotropic, orphan drug, etc URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification Binding: ProductClassification (example)
extension:sizeOfItem		0..1	Quantity	Size of one item (for example, in a pack of 5 vials, this would represent the size of 1 vial) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
extension:characteristic		0..*	(Complex)	Specifies other descriptive properties of the medication. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
extension:unitOfPresentation		0..1	CodeableConcept	Unit of presentation of the product (e.g. tablet, vial, ampoule, etc) URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation Binding: UnitOfPresentation (example)
extension:packageType		0..1	CodeableConcept	Type of container. This information is more relevant in cases when the packaging has an impact on administration of the product (e.g. pre-filled syringe) URL: http://hl7.eu/fhir/StructureDefinition/medication-package-type Binding: eHDSI Package (example)
extension:device		0..*	(Complex)	Device, typically an administration device, included in the product. URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
id		0..1	string	Unique id for inter-element referencing
Slices for extension		2..*	Extension	Extension Slice: Unordered, Open by value:url
extension:device		1..1	Extension	Extension
id		0..1	string	Unique id for inter-element referencing
extension		0..0
url		1..1	uri	"device"
value[x]		0..1	CodeableConcept	Value of extension Binding: eHDSI Package (example)
extension:quantity		1..1	Extension	Number of defined devices in te package
id		0..1	string	Unique id for inter-element referencing
extension		0..0
url		1..1	uri	"quantity"
value[x]		0..1	Quantity	Value of extension
url		1..1	uri	"https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device"
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	Identifier for the medicinal product, its generic representation, or packaged product.
code	Σ	0..1	CodeableConcept	A terminology-based code for the product Binding: SNOMEDCTMedicationCodes (example): A coded concept that defines the type of a medication.
status	?!Σ	0..1	code	active | inactive | entered-in-error Binding: Medication Status Codes (required): A coded concept defining if the medication is in active use.
manufacturer	Σ	0..1	Reference(Organization)	Manufacturer of the item
form		0..1	CodeableConcept	powder | tablets | capsule + Binding: eHDSI Dose Form (example)
amount	Σ	0..1	Ratio	Amount of drug in package
ingredient		0..*	BackboneElement	Ingredient or a part product. For combination packs, each ingredient can be a separate manufactured item with its own ingredients, dose form, and strength
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Slices for item[x]		1..1		The actual ingredient or content Slice: Unordered, Closed by type:$this
itemCodeableConcept			CodeableConcept
itemReference			Reference(Substance | Medication)
item[x]:itemReference		0..1	Reference(Medication: MPD)	The actual ingredient or content
item[x]:itemCodeableConcept		0..1	CodeableConcept	The actual ingredient or content Binding: Medicine Active Substances - IPS (example) Additional Bindings Purpose eHDSI Substance candidate
isActive		0..1	boolean	Active ingredient indicator
strength		0..1	Ratio	Amount of substance in product (presentation or concentration strength)
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
extension:basisOfStrengthSubstance		0..1	CodeableConcept	Substance for which the strength is provided (this could be different from the precise active ingredient). URL: https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance Binding: SNOMEDCTSubstanceCodes (example)
numerator	Σ	0..1	Quantity	Numerator value
denominator	Σ	0..1	Quantity	Denominator value
batch		0..1	BackboneElement	Details about packaged medications
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
lotNumber		0..1	string	Identifier assigned to batch
expirationDate		0..1	dateTime	When batch will expire
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
Medication.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages From the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
Medication.extension:device.extension:device.value[x]	example	eHDSIPackage http://terminology.ehdsi.eu/ValueSet/eHDSIPackage From http://tx.hl7europe.eu/r4
Medication.code	example	SNOMEDCTMedicationCodes http://hl7.org/fhir/ValueSet/medication-codes From the FHIR Standard
Medication.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-status|4.0.1 From the FHIR Standard
Medication.form	example	eHDSIDoseForm http://terminology.ehdsi.eu/ValueSet/eHDSIDoseForm From http://tx.hl7europe.eu/r4
Medication.ingredient.item[x]:itemCodeableConcept	example	MedicineActiveSubstancesUvIps http://hl7.org/fhir/uv/ips/ValueSet/medicine-active-substances-uv-ips

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	Medication	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Medication	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Medication	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Medication	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Medication	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

This structure is derived from Medication

Summary

Structures

This structure refers to these other structures:

• Medication: MPD (http://hl7.eu/fhir/mpd/StructureDefinition/Medication-eu-mpd)

Extensions

This structure refers to these extensions:

• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-productname
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-classification
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-sizeofitem
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-characteristic
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-unitofpresentation
• http://hl7.eu/fhir/StructureDefinition/medication-package-type
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-device
• https://profiles.ihe.net/PHARM/MPD/StructureDefinition/ihe-ext-medication-strengthsubstance

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of Medication.ingredient.item[x]

Other representations of profile: CSV, Excel, Schematron