Standardized Medication Profile (SMP) FHIR IG
1.0.0 - STU 1 United States of America flag

Standardized Medication Profile (SMP) FHIR IG, published by HL7 International / Pharmacy. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/smp-ig/ and changes regularly. See the Directory of published versions

: betsysmith-johnson01-di01-Drug-druginteraction1 - TTL Representation

Page standards status: Informative

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:DetectedIssue ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "betsysmith-johnson01-di01-Drug-druginteraction1"] ; # 
  fhir:meta [
fhir:versionId [ fhir:v "1" ] ;
fhir:lastUpdated [ fhir:v "2026-01-07T10:51:56.7250436+00:00"^^xsd:dateTime ] ;
fhir:source [
fhir:v "#fIOfmNQFLI3AB7nY"^^xsd:anyURI ;
fhir:l <#fIOfmNQFLI3AB7nY>     ] ;
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/us/smp/StructureDefinition/smp-medication-action-plan-detected-issue"^^xsd:anyURI ;
fhir:l <http://hl7.org/fhir/us/smp/StructureDefinition/smp-medication-action-plan-detected-issue>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: DetectedIssue betsysmith-johnson01-di01-Drug-druginteraction1</b></p><a name=\"betsysmith-johnson01-di01-Drug-druginteraction1\"> </a><a name=\"hcbetsysmith-johnson01-di01-Drug-druginteraction1\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 1; Last updated: 2026-01-07 10:51:56+0000; </p><p style=\"margin-bottom: 0px\">Information Source: #fIOfmNQFLI3AB7nY</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-smp-medication-action-plan-detected-issue.html\">Standardized Medication Profile - Medication Action Plan Detected Issue</a></p></div><p><b>status</b>: Preliminary</p><p><b>code</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-ActCode DRG}\">Drug Interaction Alert</span></p><p><b>severity</b>: High</p><p><b>patient</b>: <a href=\"Patient-patient-betsysmith-johnson01.html\">Smith-Johnson, Betsy Female, DoB: 1950-11-15 ( http://hl7.org/fhir/sid/us-medicare#United States Medicare Number#1PA3D58WH16)</a></p><p><b>identified</b>: 2026-01-07 10:51:56+0000</p><p><b>author</b>: <a href=\"Practitioner-Practitioner-KevinJames.html\">Practitioner Kevin James</a></p><p><b>implicated</b>: </p><ul><li><a href=\"MedicationStatement-bsj1-smp-medstmt-jardiance-1-5.html\">Jardiance Oral Tablet 10 MG (Empagliflozin)</a></li><li><a href=\"MedicationStatement-bsj1-smp-medstmt-metformin-0-12.html\">metFORMIN HCl Oral Tablet 500 MG (Metformin HCl)</a></li><li><a href=\"MedicationStatement-bsj1-smp-medstmt-sertraline-1-8.html\">Sertraline HCl Oral Tablet 25 MG (Sertraline HCl)</a></li></ul><p><b>detail</b>: Selective Serotonin Reuptake Inhibitors (eg, Sertraline HCl Oral Tablet 25 MG) may enhance the hypoglycemic effect of Agents with Blood Glucose Lowering Effects (eg, Jardiance Oral Tablet 10 MG and metFORMIN HCl Oral Tablet 500 MG)</p><h3>Mitigations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Action</b></td><td><b>Date</b></td><td><b>Author</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-ActCode 13}\">drug drug interaction, change medicine dose</span></td><td>2026-01-07 10:51:56+0000</td><td><a href=\"Practitioner-Practitioner-KevinJames.html\">Practitioner Kevin James</a></td></tr></table></div>"^^rdf:XMLLiteral ]
  ] ; # 
  fhir:status [ fhir:v "preliminary"] ; # 
  fhir:code [
    ( fhir:coding [
fhir:system [
fhir:v "http://terminology.hl7.org/CodeSystem/v3-ActCode"^^xsd:anyURI ;
fhir:l <http://terminology.hl7.org/CodeSystem/v3-ActCode>       ] ;
fhir:code [ fhir:v "DRG" ] ;
fhir:display [ fhir:v "Drug Interaction Alert" ]     ] )
  ] ; # 
  fhir:severity [ fhir:v "high"] ; # 
  fhir:patient [
fhir:l fhir:Patient/patient-betsysmith-johnson01 ;
fhir:reference [ fhir:v "Patient/patient-betsysmith-johnson01" ]
  ] ; # 
  fhir:identified [
a fhir:DateTime ;
fhir:v "2026-01-07T10:51:56.7250479+00:00"^^xsd:dateTime
  ] ; # 
  fhir:author [
fhir:l fhir:Practitioner/Practitioner-KevinJames ;
fhir:reference [ fhir:v "Practitioner/Practitioner-KevinJames" ]
  ] ; # 
  fhir:implicated ( [
fhir:l fhir:MedicationStatement/bsj1-smp-medstmt-jardiance-1-5 ;
fhir:reference [ fhir:v "MedicationStatement/bsj1-smp-medstmt-jardiance-1-5" ] ;
fhir:display [ fhir:v "Jardiance Oral Tablet 10 MG (Empagliflozin)" ]
  ] [
fhir:l fhir:MedicationStatement/bsj1-smp-medstmt-metformin-0-12 ;
fhir:reference [ fhir:v "MedicationStatement/bsj1-smp-medstmt-metformin-0-12" ] ;
fhir:display [ fhir:v "metFORMIN HCl Oral Tablet 500 MG (Metformin HCl)" ]
  ] [
fhir:l fhir:MedicationStatement/bsj1-smp-medstmt-sertraline-1-8 ;
fhir:reference [ fhir:v "MedicationStatement/bsj1-smp-medstmt-sertraline-1-8" ] ;
fhir:display [ fhir:v "Sertraline HCl Oral Tablet 25 MG (Sertraline HCl)" ]
  ] ) ; # 
  fhir:detail [ fhir:v "Selective Serotonin Reuptake Inhibitors (eg, Sertraline HCl Oral Tablet 25 MG) may enhance the hypoglycemic effect of Agents with Blood Glucose Lowering Effects (eg, Jardiance Oral Tablet 10 MG and metFORMIN HCl Oral Tablet 500 MG)"] ; # 
  fhir:mitigation ( [
fhir:action [
      ( fhir:coding [
fhir:system [
fhir:v "http://terminology.hl7.org/CodeSystem/v3-ActCode"^^xsd:anyURI ;
fhir:l <http://terminology.hl7.org/CodeSystem/v3-ActCode>         ] ;
fhir:code [ fhir:v "13" ] ;
fhir:display [ fhir:v "Stopped Concurrent Therapy" ]       ] ) ;
fhir:text [ fhir:v "drug drug interaction, change medicine dose" ]     ] ;
fhir:date [ fhir:v "2026-01-07T10:51:56.72505+00:00"^^xsd:dateTime ] ;
fhir:author [
fhir:l fhir:Practitioner/Practitioner-KevinJames ;
fhir:reference [ fhir:v "Practitioner/Practitioner-KevinJames" ]     ]
  ] ) . #