Global Core Electronic Medicinal Product Information (ePI)
1.1.0 - trial-use World

Global Core Electronic Medicinal Product Information (ePI), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/emedicinal-product-info/ and changes regularly. See the Directory of published versions

: MedicationKnowledge - Diflucan

Page standards status: Informative

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/MedicationKnowledge/mk-diflucan> a fhir:MedicationKnowledge ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "mk-diflucan"] ; # 
  fhir:meta [
     fhir:profile ( [
       fhir:v "http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/MedicationKnowledge-uv-epi"^^xsd:anyURI ;
       fhir:link <http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/MedicationKnowledge-uv-epi>
     ] )
  ] ; # 
  fhir:language [ fhir:v "en"] ; # 
  fhir:text [
     fhir:status [ fhir:v "generated" ] ;
     fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: MedicationKnowledge mk-diflucan</b></p><a name=\"mk-diflucan\"> </a><a name=\"hcmk-diflucan\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-MedicationKnowledge-uv-epi.html\">MedicationKnowledge (ePI)</a></p></div><p><b>identifier</b>: <code>http://example.org/identifier</code>/mk-diflucan</p><p><b>status</b>: Active</p><blockquote><p><b>indicationGuideline</b></p><h3>Indications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"ClinicalUseDefinition-cud-diflucan-mucosal.html\">ClinicalUseDefinition: identifier = http://example.org/identifier#cud-diflucan-mucosal; type = indication; category = Indication; status = Active</a></td></tr></table><blockquote><p><b>dosingGuideline</b></p><blockquote><p><b>dosage</b></p><p><b>type</b>: <span title=\"Codes:\">Loading dose (Day 1)</span></p><blockquote><p><b>dosage</b></p><p><b>sequence</b>: 1</p><p><b>text</b>: 200 to 400 mg on Day 1</p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>200-400 mg</td></tr></table></blockquote></blockquote><blockquote><p><b>dosage</b></p><p><b>type</b>: <span title=\"Codes:\">Maintenance</span></p><blockquote><p><b>dosage</b></p><p><b>sequence</b>: 2</p><p><b>text</b>: 100 to 200 mg once daily for 7 to 21 days</p><p><b>timing</b>: Once per 1 day</p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>100-200 mg</td></tr></table></blockquote></blockquote><h3>PatientCharacteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/epi-group-characteristic-type age}\">Age</span></td><td>18-? years</td></tr></table></blockquote><blockquote><p><b>dosingGuideline</b></p><blockquote><p><b>dosage</b></p><p><b>type</b>: <span title=\"Codes:\">Initial dose</span></p><blockquote><p><b>dosage</b></p><p><b>sequence</b>: 1</p><p><b>text</b>: 6 mg/kg on the first day</p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>6 mg/kg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg/kg = 'mg/kg')</span></td></tr></table></blockquote></blockquote><blockquote><p><b>dosage</b></p><p><b>type</b>: <span title=\"Codes:\">Subsequent dose</span></p><blockquote><p><b>dosage</b></p><p><b>sequence</b>: 2</p><p><b>text</b>: 3 mg/kg once daily</p><p><b>timing</b>: Once per 1 day</p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>3 mg/kg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg/kg = 'mg/kg')</span></td></tr></table></blockquote></blockquote><h3>PatientCharacteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/epi-group-characteristic-type age}\">Age</span></td><td>28-11 days</td></tr></table></blockquote><blockquote><p><b>dosingGuideline</b></p><blockquote><p><b>dosage</b></p><p><b>type</b>: <span title=\"Codes:\">Neonatal dose</span></p><blockquote><p><b>dosage</b></p><p><b>sequence</b>: 1</p><p><b>text</b>: 3 mg/kg every 72 hours (max 12 mg/kg every 72 hours)</p><p><b>timing</b>: Once per 72 hours</p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>3 mg/kg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg/kg = 'mg/kg')</span></td></tr></table><p><b>maxDosePerPeriod</b>: 12 mg/kg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg/kg = 'mg/kg')</span>/72 hours<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeh = 'h')</span></p></blockquote></blockquote><h3>PatientCharacteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/epi-group-characteristic-type age}\">Age</span></td><td>0-14 days</td></tr></table></blockquote></blockquote><blockquote><p><b>indicationGuideline</b></p><h3>Indications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"ClinicalUseDefinition-cud-diflucan-invasive.html\">ClinicalUseDefinition: identifier = http://example.org/identifier#cud-diflucan-invasive; type = indication; category = Indication; status = Active</a></td></tr></table><blockquote><p><b>dosingGuideline</b></p><blockquote><p><b>dosage</b></p><p><b>type</b>: <span title=\"Codes:\">Loading dose (Day 1)</span></p><blockquote><p><b>dosage</b></p><p><b>sequence</b>: 1</p><p><b>text</b>: 800 mg on Day 1</p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>800 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg = 'mg')</span></td></tr></table></blockquote></blockquote><blockquote><p><b>dosage</b></p><p><b>type</b>: <span title=\"Codes:\">Maintenance</span></p><blockquote><p><b>dosage</b></p><p><b>sequence</b>: 2</p><p><b>text</b>: 400 mg once daily</p><p><b>timing</b>: Once per 1 day</p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>400 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg = 'mg')</span></td></tr></table></blockquote></blockquote></blockquote></blockquote></div>"^^rdf:XMLLiteral ]
  ] ; # 
  fhir:identifier ( [
     fhir:system [ fhir:v "http://example.org/identifier"^^xsd:anyURI ] ;
     fhir:value [ fhir:v "mk-diflucan" ]
  ] ) ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:indicationGuideline ( [
     fhir:indication ( [
       fhir:reference [
         fhir:link <http://hl7.org/fhir/ClinicalUseDefinition/cud-diflucan-mucosal> ;
         fhir:reference [ fhir:v "ClinicalUseDefinition/cud-diflucan-mucosal" ]
       ]
     ] ) ;
     fhir:dosingGuideline ( [
       fhir:dosage ( [
         fhir:type [
           fhir:text [ fhir:v "Loading dose (Day 1)" ]
         ] ;
         fhir:dosage ( [
           fhir:sequence [ fhir:v 1 ] ;
           fhir:text [ fhir:v "200 to 400 mg on Day 1" ] ;
           fhir:doseAndRate ( [
             fhir:dose [
               a fhir:Range ;
               fhir:low [
                 fhir:value [ fhir:v "200"^^xsd:decimal ] ;
                 fhir:unit [ fhir:v "mg" ] ;
                 fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
                 fhir:code [ fhir:v "mg" ]
               ] ;
               fhir:high [
                 fhir:value [ fhir:v "400"^^xsd:decimal ] ;
                 fhir:unit [ fhir:v "mg" ] ;
                 fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
                 fhir:code [ fhir:v "mg" ]
               ]
             ]
           ] )
         ] )
       ] [
         fhir:type [
           fhir:text [ fhir:v "Maintenance" ]
         ] ;
         fhir:dosage ( [
           fhir:sequence [ fhir:v 2 ] ;
           fhir:text [ fhir:v "100 to 200 mg once daily for 7 to 21 days" ] ;
           fhir:timing [
             fhir:repeat [
               fhir:frequency [ fhir:v "1"^^xsd:positiveInteger ] ;
               fhir:period [ fhir:v "1"^^xsd:decimal ] ;
               fhir:periodUnit [ fhir:v "d" ]
             ]
           ] ;
           fhir:doseAndRate ( [
             fhir:dose [
               a fhir:Range ;
               fhir:low [
                 fhir:value [ fhir:v "100"^^xsd:decimal ] ;
                 fhir:unit [ fhir:v "mg" ] ;
                 fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
                 fhir:code [ fhir:v "mg" ]
               ] ;
               fhir:high [
                 fhir:value [ fhir:v "200"^^xsd:decimal ] ;
                 fhir:unit [ fhir:v "mg" ] ;
                 fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
                 fhir:code [ fhir:v "mg" ]
               ]
             ]
           ] )
         ] )
       ] ) ;
       fhir:patientCharacteristic ( [
         fhir:type [
           fhir:coding ( [
             fhir:system [ fhir:v "http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/epi-group-characteristic-type"^^xsd:anyURI ] ;
             fhir:code [ fhir:v "age" ] ;
             fhir:display [ fhir:v "Age" ]
           ] )
         ] ;
         fhir:value [
           a fhir:Range ;
           fhir:low [
             fhir:value [ fhir:v "18"^^xsd:decimal ] ;
             fhir:unit [ fhir:v "years" ] ;
             fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
             fhir:code [ fhir:v "a" ]
           ]
         ]
       ] )
     ] [
       fhir:dosage ( [
         fhir:type [
           fhir:text [ fhir:v "Initial dose" ]
         ] ;
         fhir:dosage ( [
           fhir:sequence [ fhir:v 1 ] ;
           fhir:text [ fhir:v "6 mg/kg on the first day" ] ;
           fhir:doseAndRate ( [
             fhir:dose [
               a fhir:Quantity ;
               fhir:value [ fhir:v "6"^^xsd:decimal ] ;
               fhir:unit [ fhir:v "mg/kg" ] ;
               fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
               fhir:code [ fhir:v "mg/kg" ]
             ]
           ] )
         ] )
       ] [
         fhir:type [
           fhir:text [ fhir:v "Subsequent dose" ]
         ] ;
         fhir:dosage ( [
           fhir:sequence [ fhir:v 2 ] ;
           fhir:text [ fhir:v "3 mg/kg once daily" ] ;
           fhir:timing [
             fhir:repeat [
               fhir:frequency [ fhir:v "1"^^xsd:positiveInteger ] ;
               fhir:period [ fhir:v "1"^^xsd:decimal ] ;
               fhir:periodUnit [ fhir:v "d" ]
             ]
           ] ;
           fhir:doseAndRate ( [
             fhir:dose [
               a fhir:Quantity ;
               fhir:value [ fhir:v "3"^^xsd:decimal ] ;
               fhir:unit [ fhir:v "mg/kg" ] ;
               fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
               fhir:code [ fhir:v "mg/kg" ]
             ]
           ] )
         ] )
       ] ) ;
       fhir:patientCharacteristic ( [
         fhir:type [
           fhir:coding ( [
             fhir:system [ fhir:v "http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/epi-group-characteristic-type"^^xsd:anyURI ] ;
             fhir:code [ fhir:v "age" ] ;
             fhir:display [ fhir:v "Age" ]
           ] )
         ] ;
         fhir:value [
           a fhir:Range ;
           fhir:low [
             fhir:value [ fhir:v "28"^^xsd:decimal ] ;
             fhir:unit [ fhir:v "days" ] ;
             fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
             fhir:code [ fhir:v "d" ]
           ] ;
           fhir:high [
             fhir:value [ fhir:v "11"^^xsd:decimal ] ;
             fhir:unit [ fhir:v "years" ] ;
             fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
             fhir:code [ fhir:v "a" ]
           ]
         ]
       ] )
     ] [
       fhir:dosage ( [
         fhir:type [
           fhir:text [ fhir:v "Neonatal dose" ]
         ] ;
         fhir:dosage ( [
           fhir:sequence [ fhir:v 1 ] ;
           fhir:text [ fhir:v "3 mg/kg every 72 hours (max 12 mg/kg every 72 hours)" ] ;
           fhir:timing [
             fhir:repeat [
               fhir:frequency [ fhir:v "1"^^xsd:positiveInteger ] ;
               fhir:period [ fhir:v "72"^^xsd:decimal ] ;
               fhir:periodUnit [ fhir:v "h" ]
             ]
           ] ;
           fhir:doseAndRate ( [
             fhir:dose [
               a fhir:Quantity ;
               fhir:value [ fhir:v "3"^^xsd:decimal ] ;
               fhir:unit [ fhir:v "mg/kg" ] ;
               fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
               fhir:code [ fhir:v "mg/kg" ]
             ]
           ] ) ;
           fhir:maxDosePerPeriod ( [
             fhir:numerator [
               fhir:value [ fhir:v "12"^^xsd:decimal ] ;
               fhir:unit [ fhir:v "mg/kg" ] ;
               fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
               fhir:code [ fhir:v "mg/kg" ]
             ] ;
             fhir:denominator [
               fhir:value [ fhir:v "72"^^xsd:decimal ] ;
               fhir:unit [ fhir:v "hours" ] ;
               fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
               fhir:code [ fhir:v "h" ]
             ]
           ] )
         ] )
       ] ) ;
       fhir:patientCharacteristic ( [
         fhir:type [
           fhir:coding ( [
             fhir:system [ fhir:v "http://hl7.org/fhir/uv/emedicinal-product-info/CodeSystem/epi-group-characteristic-type"^^xsd:anyURI ] ;
             fhir:code [ fhir:v "age" ] ;
             fhir:display [ fhir:v "Age" ]
           ] )
         ] ;
         fhir:value [
           a fhir:Range ;
           fhir:low [
             fhir:value [ fhir:v "0"^^xsd:decimal ] ;
             fhir:unit [ fhir:v "days" ] ;
             fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
             fhir:code [ fhir:v "d" ]
           ] ;
           fhir:high [
             fhir:value [ fhir:v "14"^^xsd:decimal ] ;
             fhir:unit [ fhir:v "days" ] ;
             fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
             fhir:code [ fhir:v "d" ]
           ]
         ]
       ] )
     ] )
  ] [
     fhir:indication ( [
       fhir:reference [
         fhir:link <http://hl7.org/fhir/ClinicalUseDefinition/cud-diflucan-invasive> ;
         fhir:reference [ fhir:v "ClinicalUseDefinition/cud-diflucan-invasive" ]
       ]
     ] ) ;
     fhir:dosingGuideline ( [
       fhir:dosage ( [
         fhir:type [
           fhir:text [ fhir:v "Loading dose (Day 1)" ]
         ] ;
         fhir:dosage ( [
           fhir:sequence [ fhir:v 1 ] ;
           fhir:text [ fhir:v "800 mg on Day 1" ] ;
           fhir:doseAndRate ( [
             fhir:dose [
               a fhir:Quantity ;
               fhir:value [ fhir:v "800"^^xsd:decimal ] ;
               fhir:unit [ fhir:v "mg" ] ;
               fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
               fhir:code [ fhir:v "mg" ]
             ]
           ] )
         ] )
       ] [
         fhir:type [
           fhir:text [ fhir:v "Maintenance" ]
         ] ;
         fhir:dosage ( [
           fhir:sequence [ fhir:v 2 ] ;
           fhir:text [ fhir:v "400 mg once daily" ] ;
           fhir:timing [
             fhir:repeat [
               fhir:frequency [ fhir:v "1"^^xsd:positiveInteger ] ;
               fhir:period [ fhir:v "1"^^xsd:decimal ] ;
               fhir:periodUnit [ fhir:v "d" ]
             ]
           ] ;
           fhir:doseAndRate ( [
             fhir:dose [
               a fhir:Quantity ;
               fhir:value [ fhir:v "400"^^xsd:decimal ] ;
               fhir:unit [ fhir:v "mg" ] ;
               fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
               fhir:code [ fhir:v "mg" ]
             ]
           ] )
         ] )
       ] )
     ] )
  ] ) . # 

<http://hl7.org/fhir/ClinicalUseDefinition/cud-diflucan-mucosal> a fhir:ClinicalUseDefinition .

<http://hl7.org/fhir/ClinicalUseDefinition/cud-diflucan-invasive> a fhir:ClinicalUseDefinition .