HL7 Terminology (THO)
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HL7 Terminology (THO), published by HL7 International - Vocabulary Work Group. This guide is not an authorized publication; it is the continuous build for version 7.4.11 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/UTG/ and changes regularly. See the Directory of published versions

: Detected Issue Clinical Impact

Page standards status: Trial-use Maturity Level: 3

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<CodeSystem xmlns="http://hl7.org/fhir">
  <id value="detectedissue-clinical-impact"/>
  <language value="en"/>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: CodeSystem detectedissue-clinical-impact</b></p><a name="detectedissue-clinical-impact"> </a><a name="hcdetectedissue-clinical-impact"> </a><p>This case-sensitive code system <code>http://terminology.hl7.org/CodeSystem/detectedissue-clinical-impact</code> defines the following codes:</p><table class="codes"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style="white-space:nowrap">increased-effect<a name="detectedissue-clinical-impact-increased-effect"> </a></td><td>Increased effect</td><td>The clinical or pharmacologic effect is expected to be increased for one or more implicated therapies.</td></tr><tr><td style="white-space:nowrap">decreased-effect<a name="detectedissue-clinical-impact-decreased-effect"> </a></td><td>Decreased effect</td><td>The clinical or pharmacologic effect is expected to be decreased for one or more implicated therapies.</td></tr><tr><td style="white-space:nowrap">mixed-effect<a name="detectedissue-clinical-impact-mixed-effect"> </a></td><td>Mixed effect</td><td>Mixed or differing changes in clinical or pharmacologic effects are expected.</td></tr><tr><td style="white-space:nowrap">adverse-reaction<a name="detectedissue-clinical-impact-adverse-reaction"> </a></td><td>Adverse reaction</td><td>An adverse reaction is expected or its risk is increased.</td></tr><tr><td style="white-space:nowrap">additive-adverse-effects<a name="detectedissue-clinical-impact-additive-adverse-effects"> </a></td><td>Additive adverse effects</td><td>Adverse or undesirable effects are expected to be additive for one or more implicated therapies.</td></tr><tr><td style="white-space:nowrap">avoid-concurrent-use<a name="detectedissue-clinical-impact-avoid-concurrent-use"> </a></td><td>Avoid concurrent use when possible</td><td>Concurrent use should generally be avoided because of the identified clinical risk.</td></tr><tr><td style="white-space:nowrap">contraindicated-in-some-patients<a name="detectedissue-clinical-impact-contraindicated-in-some-patients"> </a></td><td>Contraindicated in some patients</td><td>Concurrent use is contraindicated for a subset of patients based on patient-specific clinical characteristics or circumstances.</td></tr></table></div>
  </text>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
    <valueCode value="cds"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
    <valueCode value="trial-use"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">
    <valueInteger value="3"/>
  </extension>
  <url
       value="http://terminology.hl7.org/CodeSystem/detectedissue-clinical-impact"/>
  <version value="1.0.0"/>
  <name value="DetectedIssueClinicalImpact"/>
  <title value="Detected Issue Clinical Impact"/>
  <status value="active"/>
  <experimental value="false"/>
  <date value="2026-09-14"/>
  <publisher value="Health Level Seven International"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="http://hl7.org"/>
    </telecom>
    <telecom>
      <system value="email"/>
      <value value="hq@HL7.org"/>
    </telecom>
  </contact>
  <description
               value="Codes that describe the potential clinical impact of a detected issue."/>
  <copyright
             value="This material derives from the HL7 Terminology (THO). THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license"/>
  <caseSensitive value="true"/>
  <valueSet
            value="http://terminology.hl7.org/ValueSet/detectedissue-clinical-impact"/>
  <content value="complete"/>
  <concept>
    <code value="increased-effect"/>
    <display value="Increased effect"/>
    <definition
                value="The clinical or pharmacologic effect is expected to be increased for one or more implicated therapies."/>
  </concept>
  <concept>
    <code value="decreased-effect"/>
    <display value="Decreased effect"/>
    <definition
                value="The clinical or pharmacologic effect is expected to be decreased for one or more implicated therapies."/>
  </concept>
  <concept>
    <code value="mixed-effect"/>
    <display value="Mixed effect"/>
    <definition
                value="Mixed or differing changes in clinical or pharmacologic effects are expected."/>
  </concept>
  <concept>
    <code value="adverse-reaction"/>
    <display value="Adverse reaction"/>
    <definition
                value="An adverse reaction is expected or its risk is increased."/>
  </concept>
  <concept>
    <code value="additive-adverse-effects"/>
    <display value="Additive adverse effects"/>
    <definition
                value="Adverse or undesirable effects are expected to be additive for one or more implicated therapies."/>
  </concept>
  <concept>
    <code value="avoid-concurrent-use"/>
    <display value="Avoid concurrent use when possible"/>
    <definition
                value="Concurrent use should generally be avoided because of the identified clinical risk."/>
  </concept>
  <concept>
    <code value="contraindicated-in-some-patients"/>
    <display value="Contraindicated in some patients"/>
    <definition
                value="Concurrent use is contraindicated for a subset of patients based on patient-specific clinical characteristics or circumstances."/>
  </concept>
</CodeSystem>