HL7 Terminology (THO)
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HL7 Terminology (THO), published by HL7 International - Vocabulary Work Group. This guide is not an authorized publication; it is the continuous build for version 7.4.11 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/UTG/ and changes regularly. See the Directory of published versions

: Detected Issue Clinical Impact

Page standards status: Trial-use Maturity Level: 3

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/CodeSystem/detectedissue-clinical-impact> a fhir:CodeSystem ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "detectedissue-clinical-impact"] ; # 
  fhir:language [ fhir:v "en"] ; # 
  fhir:text [
     fhir:status [ fhir:v "generated" ] ;
     fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem detectedissue-clinical-impact</b></p><a name=\"detectedissue-clinical-impact\"> </a><a name=\"hcdetectedissue-clinical-impact\"> </a><p>This case-sensitive code system <code>http://terminology.hl7.org/CodeSystem/detectedissue-clinical-impact</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">increased-effect<a name=\"detectedissue-clinical-impact-increased-effect\"> </a></td><td>Increased effect</td><td>The clinical or pharmacologic effect is expected to be increased for one or more implicated therapies.</td></tr><tr><td style=\"white-space:nowrap\">decreased-effect<a name=\"detectedissue-clinical-impact-decreased-effect\"> </a></td><td>Decreased effect</td><td>The clinical or pharmacologic effect is expected to be decreased for one or more implicated therapies.</td></tr><tr><td style=\"white-space:nowrap\">mixed-effect<a name=\"detectedissue-clinical-impact-mixed-effect\"> </a></td><td>Mixed effect</td><td>Mixed or differing changes in clinical or pharmacologic effects are expected.</td></tr><tr><td style=\"white-space:nowrap\">adverse-reaction<a name=\"detectedissue-clinical-impact-adverse-reaction\"> </a></td><td>Adverse reaction</td><td>An adverse reaction is expected or its risk is increased.</td></tr><tr><td style=\"white-space:nowrap\">additive-adverse-effects<a name=\"detectedissue-clinical-impact-additive-adverse-effects\"> </a></td><td>Additive adverse effects</td><td>Adverse or undesirable effects are expected to be additive for one or more implicated therapies.</td></tr><tr><td style=\"white-space:nowrap\">avoid-concurrent-use<a name=\"detectedissue-clinical-impact-avoid-concurrent-use\"> </a></td><td>Avoid concurrent use when possible</td><td>Concurrent use should generally be avoided because of the identified clinical risk.</td></tr><tr><td style=\"white-space:nowrap\">contraindicated-in-some-patients<a name=\"detectedissue-clinical-impact-contraindicated-in-some-patients\"> </a></td><td>Contraindicated in some patients</td><td>Concurrent use is contraindicated for a subset of patients based on patient-specific clinical characteristics or circumstances.</td></tr></table></div>"^^rdf:XMLLiteral ]
  ] ; # 
  fhir:extension ( [
     fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg"^^xsd:anyURI ] ;
     fhir:value [
       a fhir:code ;
       fhir:v "cds"
     ]
  ] [
     fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"^^xsd:anyURI ] ;
     fhir:value [
       a fhir:code ;
       fhir:v "trial-use"
     ]
  ] [
     fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm"^^xsd:anyURI ] ;
     fhir:value [
       a fhir:integer ;
       fhir:v 3
     ]
  ] ) ; # 
  fhir:url [ fhir:v "http://terminology.hl7.org/CodeSystem/detectedissue-clinical-impact"^^xsd:anyURI] ; # 
  fhir:version [ fhir:v "1.0.0"] ; # 
  fhir:name [ fhir:v "DetectedIssueClinicalImpact"] ; # 
  fhir:title [ fhir:v "Detected Issue Clinical Impact"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:experimental [ fhir:v false] ; # 
  fhir:date [ fhir:v "2026-09-14"^^xsd:date] ; # 
  fhir:publisher [ fhir:v "Health Level Seven International"] ; # 
  fhir:contact ( [
     fhir:telecom ( [
       fhir:system [ fhir:v "url" ] ;
       fhir:value [ fhir:v "http://hl7.org" ]
     ] [
       fhir:system [ fhir:v "email" ] ;
       fhir:value [ fhir:v "hq@HL7.org" ]
     ] )
  ] ) ; # 
  fhir:description [ fhir:v "Codes that describe the potential clinical impact of a detected issue."] ; # 
  fhir:copyright [ fhir:v "This material derives from the HL7 Terminology (THO). THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license"] ; # 
  fhir:caseSensitive [ fhir:v true] ; # 
  fhir:valueSet [
     fhir:v "http://terminology.hl7.org/ValueSet/detectedissue-clinical-impact"^^xsd:anyURI ;
     fhir:link <http://terminology.hl7.org/ValueSet/detectedissue-clinical-impact>
  ] ; # 
  fhir:content [ fhir:v "complete"] ; # 
  fhir:concept ( [
     fhir:code [ fhir:v "increased-effect" ] ;
     fhir:display [ fhir:v "Increased effect" ] ;
     fhir:definition [ fhir:v "The clinical or pharmacologic effect is expected to be increased for one or more implicated therapies." ]
  ] [
     fhir:code [ fhir:v "decreased-effect" ] ;
     fhir:display [ fhir:v "Decreased effect" ] ;
     fhir:definition [ fhir:v "The clinical or pharmacologic effect is expected to be decreased for one or more implicated therapies." ]
  ] [
     fhir:code [ fhir:v "mixed-effect" ] ;
     fhir:display [ fhir:v "Mixed effect" ] ;
     fhir:definition [ fhir:v "Mixed or differing changes in clinical or pharmacologic effects are expected." ]
  ] [
     fhir:code [ fhir:v "adverse-reaction" ] ;
     fhir:display [ fhir:v "Adverse reaction" ] ;
     fhir:definition [ fhir:v "An adverse reaction is expected or its risk is increased." ]
  ] [
     fhir:code [ fhir:v "additive-adverse-effects" ] ;
     fhir:display [ fhir:v "Additive adverse effects" ] ;
     fhir:definition [ fhir:v "Adverse or undesirable effects are expected to be additive for one or more implicated therapies." ]
  ] [
     fhir:code [ fhir:v "avoid-concurrent-use" ] ;
     fhir:display [ fhir:v "Avoid concurrent use when possible" ] ;
     fhir:definition [ fhir:v "Concurrent use should generally be avoided because of the identified clinical risk." ]
  ] [
     fhir:code [ fhir:v "contraindicated-in-some-patients" ] ;
     fhir:display [ fhir:v "Contraindicated in some patients" ] ;
     fhir:definition [ fhir:v "Concurrent use is contraindicated for a subset of patients based on patient-specific clinical characteristics or circumstances." ]
  ] ) . #