Clinical Practice Guidelines (CPG) on EBMonFHIR
1.0.2 - ci-build

Clinical Practice Guidelines (CPG) on EBMonFHIR, published by Universitätsmedizin Greifswald. This guide is not an authorized publication; it is the continuous build for version 1.0.2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/CEOsys/cpg-on-ebm-on-fhir/ and changes regularly. See the Directory of published versions

: COVID19 Intensive Care Treatment Guideline - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Bundle ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "COVID19IntensiveCareTreatmentGuidelineBundle"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/guideline-bundle"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/guideline-bundle>     ] )
  ] ; # 
  fhir:type [ fhir:v "collection"] ; # 
  fhir:entry ( [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/guideline"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/guideline> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/guideline-citation"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/guideline-citation> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-plan-ventilated-patients"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-plan-ventilated-patients> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-plan-non-ventilated-patients"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-plan-non-ventilated-patients> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-oral"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-oral> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-intravenous"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-intravenous> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-no-application"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-no-application> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-citation"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-citation> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-ventilated"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-ventilated> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-non-ventilated"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-non-ventilated> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/rating-outcome-mortality"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/rating-outcome-mortality> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/outcome-mortality"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/outcome-mortality> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/study-eligibility-criteria"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/study-eligibility-criteria> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/outcome-all-cause-mortality"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/outcome-all-cause-mortality> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-justification"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-justification> )
  ] [
fhir:fullUrl [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/study-citation"^^xsd:anyURI ] ;
    ( fhir:resource <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/study-citation> )
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/guideline> a fhir:Composition ;
  fhir:id [ fhir:v "COVID19IntensiveCareTreatmentGuideline"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/guideline"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/guideline>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Composition_COVID19IntensiveCareTreatmentGuideline\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Composition COVID19IntensiveCareTreatmentGuideline</b></p><a name=\"COVID19IntensiveCareTreatmentGuideline\"> </a><a name=\"hcCOVID19IntensiveCareTreatmentGuideline\"> </a><a name=\"COVID19IntensiveCareTreatmentGuideline-en-US\"> </a><p><b>identifier</b>: Resource identifier/113-001</p><p><b>version</b>: 7.0</p><p><b>status</b>: Final</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system clinical-practice-guideline}, {https://data.cochrane.org/concepts/ e07eN1w1Rwswg4}\">Guidelines</span></p><p><b>category</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-guideline-stage-classification S3}\">Evidence- and consensus-based guideline</span></p><p><b>date</b>: 2022-03-01</p><p><b>author</b>: <a href=\"Organization-AWMFOrganization.html\">Organization Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) e.V.</a></p><p><b>title</b>: Empfehlungen zur stationären Therapie von Patienten mit COVID-19 - Living Guideline</p><h3>RelatesTos</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>Citation</td><td><a href=\"Citation-COVID19IntensiveCareTreatmentGuidelineCitation.html\">Citation COVID19_Intensive_Care_Treatment_Guideline</a></td></tr></table></div>"
  ] ; # 
  fhir:identifier ( [
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ;
fhir:code [ fhir:v "RI" ] ;
fhir:display [ fhir:v "Resource identifier" ]       ] )     ] ;
fhir:system [ fhir:v "https://www.awmf.org/"^^xsd:anyURI ] ;
fhir:value [ fhir:v "113-001" ]
  ] ) ; # 
  fhir:version [ fhir:v "7.0"] ; # 
  fhir:status [ fhir:v "final"] ; # 
  fhir:type [
    ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "clinical-practice-guideline" ]     ] [
fhir:system [ fhir:v "https://data.cochrane.org/concepts/"^^xsd:anyURI ] ;
fhir:code [ fhir:v "e07eN1w1Rwswg4" ] ;
fhir:display [ fhir:v "Guidelines" ]     ] )
  ] ; # 
  fhir:category ( [
    ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-guideline-stage-classification"^^xsd:anyURI ] ;
fhir:code [ fhir:v "S3" ] ;
fhir:display [ fhir:v "Evidence- and consensus-based guideline" ]     ] )
  ] ) ; # 
  fhir:date [ fhir:v "2022-03-01"^^xsd:date] ; # 
  fhir:author ( [
fhir:reference [ fhir:v "Organization/AWMFOrganization" ]
  ] ) ; # 
  fhir:title [ fhir:v "Empfehlungen zur stationären Therapie von Patienten mit COVID-19 - Living Guideline"] ; # 
  fhir:relatesTo ( [
fhir:type [ fhir:v "citation" ] ;
fhir:resourceReference [
fhir:reference [ fhir:v "Citation/COVID19IntensiveCareTreatmentGuidelineCitation" ]     ]
  ] ) ; # 
  fhir:section ( [
fhir:title [ fhir:v "Stationäre Therapie von COVID-19 Patienten" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "guideline-recommendation" ] ;
fhir:display [ fhir:v "Clinical practice guideline recommendation" ]       ] )     ] ;
fhir:focus [
fhir:reference [ fhir:v "PlanDefinition/COVID19VentilatedPatientsDexamethasoneApplicationPlan" ]     ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><strong>Systemische Steroide:</strong> Bei Patienten mit COVID-19- und Sauerstoff-Bedarf (Niedrigfluss-Sauerstoff-Insufflation, High-Flow Nasal Cannula, Nichtinvasive Beatmung/CPAP, invasive Beatmung) soll eine Therapie mit systemischen Kortikosteroiden erfolgen. Die Therapie sollte mit 6 mg Dexamethason p.o. oder i.v. über zehn Tage erfolgen.</div>"     ]
  ] [
fhir:title [ fhir:v "Stationäre Therapie von COVID-19 Patienten" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "guideline-recommendation" ] ;
fhir:display [ fhir:v "Clinical practice guideline recommendation" ]       ] )     ] ;
fhir:focus [
fhir:reference [ fhir:v "PlanDefinition/COVID19NonVentilatedPatientsDexamethasoneApplicationPlan" ]     ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><strong>Systemische Steroide:</strong> Bei Patienten mit moderater Erkrankung (hospitalisiert ohne Notwendigkeit von Niedrigfluss-Sauerstoff-Insufflation) soll keine Therapie mit systemischen Kortikosteroiden erfolgen.</div>"     ]
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/guideline-citation> a fhir:Citation ;
  fhir:id [ fhir:v "COVID19IntensiveCareTreatmentGuidelineCitation"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/guideline-citation"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/guideline-citation>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Citation_COVID19IntensiveCareTreatmentGuidelineCitation\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Citation COVID19IntensiveCareTreatmentGuidelineCitation</b></p><a name=\"COVID19IntensiveCareTreatmentGuidelineCitation\"> </a><a name=\"hcCOVID19IntensiveCareTreatmentGuidelineCitation\"> </a><a name=\"COVID19IntensiveCareTreatmentGuidelineCitation-en-US\"> </a><p><b>name</b>: COVID19_Intensive_Care_Treatment_Guideline</p><p><b>status</b>: Active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: <code>https://www.awmf.org/</code>/113-001</p><h3>Versions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Value</b></td></tr><tr><td style=\"display: none\">*</td><td>7.0</td></tr></table><p><b>currentState</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-status-type active}\">Active</span></p><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td><div><p>S3-Leitlinie Stationäre Therapie von COVID-19 Patienten</p>\n</div></td></tr></table><h3>WebLocations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Url</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://www.awmf.org/leitlinien/detail/ll/113-001.html\">https://www.awmf.org/leitlinien/detail/ll/113-001.html</a></td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type publication-type}\">Publication Type</span></td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system clinical-practice-guideline}\">Clinical practice guideline</span></td></tr></table></blockquote></div>"
  ] ; # 
  fhir:name [ fhir:v "COVID19_Intensive_Care_Treatment_Guideline"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:citedArtifact [
    ( fhir:identifier [
fhir:system [ fhir:v "https://www.awmf.org/"^^xsd:anyURI ] ;
fhir:value [ fhir:v "113-001" ]     ] ) ;
fhir:version [
fhir:value [ fhir:v "7.0" ]     ] ;
    ( fhir:currentState [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-status-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "active" ] ;
fhir:display [ fhir:v "Active" ]       ] )     ] ) ;
    ( fhir:title [
fhir:text [ fhir:v "S3-Leitlinie Stationäre Therapie von COVID-19 Patienten" ]     ] ) ;
    ( fhir:webLocation [
fhir:url [ fhir:v "https://www.awmf.org/leitlinien/detail/ll/113-001.html"^^xsd:anyURI ]     ] ) ;
    ( fhir:classification [
fhir:type [
        ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "publication-type" ] ;
fhir:display [ fhir:v "Publication Type" ]         ] )       ] ;
      ( fhir:classifier [
        ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "clinical-practice-guideline" ] ;
fhir:display [ fhir:v "Clinical practice guideline" ]         ] )       ] )     ] )
  ] . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation> a fhir:PlanDefinition ;
  fhir:id [ fhir:v "COVID19DexamethasoneApplication"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_COVID19DexamethasoneApplication\"> </a><p class=\"res-header-id\"><b>Generated Narrative: PlanDefinition COVID19DexamethasoneApplication</b></p><a name=\"COVID19DexamethasoneApplication\"> </a><a name=\"hcCOVID19DexamethasoneApplication\"> </a><a name=\"COVID19DexamethasoneApplication-en-US\"> </a><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><blockquote><p><b>Action Combination Method</b></p><ul><li>method: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method one-or-more}\">One or More</span></li></ul></blockquote><p><b>url</b>: <a href=\"PlanDefinition-COVID19DexamethasoneApplication.html\">PlanDefinition Dexamethasone Application</a></p><p><b>version</b>: 4.0</p><p><b>name</b>: Dexamethasone_Application</p><p><b>title</b>: Dexamethasone Application</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/plan-definition-type workflow-definition}\">Workflow Definition</span></p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href=\"EvidenceVariable-PopulationCOVID19Ventilated.html\">Population_COVID19_Ventilated</a></p><p><b>date</b>: 2021-12-12</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>Application of Dexamethasone for ventilated patients only</p>\n</div><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>Justification</td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system recommendation-rating}\">Recommendation rating</span></td><td><a href=\"ArtifactAssessment-DexamethasoneRecommendationJustification.html\">ArtifactAssessment: extension = v4.0,active; date = 2020-01-03; artifact[x] = -&gt;PlanDefinition Dexamethasone Application in ventilated COVID-19 patients</a></td></tr><tr><td style=\"display: none\">*</td><td>Citation</td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system guideline-recommendation}\">Clinical practice guideline recommendation</span></td><td><a href=\"Citation-DexamethasoneRecommendationCitation.html\">Citation DexamethasoneRecommendationCitation</a></td></tr><tr><td style=\"display: none\">*</td><td>Citation</td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system clinical-practice-guideline}\">Clinical practice guideline</span></td><td><a href=\"Citation-COVID19IntensiveCareTreatmentGuidelineCitation.html\">Citation COVID19_Intensive_Care_Treatment_Guideline</a></td></tr></table><blockquote><p><b>action</b></p><p><b>title</b>: Dexamethasone Application</p><p><b>description</b>: </p><div><p>Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients</p>\n</div><p><b>code</b>: <span title=\"Codes:{http://hl7.org/fhir/uv/cpg/CodeSystem/cpg-common-process guideline-based-care}\">Guideline-based Care</span></p><p><b>definition</b>: <a href=\"PlanDefinition-COVID19VentilatedPatientsDexamethasoneApplicationPlan.html\">Dexamethasone Application in ventilated COVID-19 patients</a></p></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: No Dexamethasone Application</p><p><b>description</b>: </p><div><p>No Dexamethasone Application for non-ventilated COVID-19 patients</p>\n</div><p><b>code</b>: <span title=\"Codes:{http://hl7.org/fhir/uv/cpg/CodeSystem/cpg-common-process guideline-based-care}\">Guideline-based Care</span></p><p><b>definition</b>: <a href=\"PlanDefinition-COVID19NonVentilatedPatientsDexamethasoneApplicationPlan.html\">No Dexamethasone Application for non-ventilated COVID-19 patients</a></p></blockquote></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability"^^xsd:anyURI ] ;
fhir:value [ fhir:v "computable" ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel"^^xsd:anyURI ] ;
fhir:value [ fhir:v "structured" ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "method"^^xsd:anyURI ] ;
fhir:value [
a fhir:CodeableConcept ;
        ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method"^^xsd:anyURI ] ;
fhir:code [ fhir:v "one-or-more" ]         ] )       ]     ] ) ;
fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-action-combination-method"^^xsd:anyURI ]
  ] ) ; # 
  fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-dexamethasone-recommendation"^^xsd:anyURI] ; # 
  fhir:version [ fhir:v "4.0"] ; # 
  fhir:name [ fhir:v "Dexamethasone_Application"] ; # 
  fhir:title [ fhir:v "Dexamethasone Application"] ; # 
  fhir:type [
    ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/plan-definition-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "workflow-definition" ]     ] )
  ] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:experimental [ fhir:v "true"^^xsd:boolean] ; # 
  fhir:subject [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_Ventilated"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_Ventilated>
  ] ; # 
  fhir:date [ fhir:v "2021-12-12"^^xsd:date] ; # 
  fhir:publisher [ fhir:v "CPGonEBMonFHIR"] ; # 
  fhir:description [ fhir:v "Application of Dexamethasone for ventilated patients only"] ; # 
  fhir:relatedArtifact ( [
fhir:type [ fhir:v "justification" ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "recommendation-rating" ] ;
fhir:display [ fhir:v "Recommendation rating" ]       ] )     ] ) ;
fhir:resourceReference [
fhir:reference [ fhir:v "ArtifactAssessment/DexamethasoneRecommendationJustification" ]     ]
  ] [
fhir:type [ fhir:v "citation" ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "guideline-recommendation" ] ;
fhir:display [ fhir:v "Clinical practice guideline recommendation" ]       ] )     ] ) ;
fhir:resourceReference [
fhir:reference [ fhir:v "Citation/DexamethasoneRecommendationCitation" ]     ]
  ] [
fhir:type [ fhir:v "citation" ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "clinical-practice-guideline" ] ;
fhir:display [ fhir:v "Clinical practice guideline" ]       ] )     ] ) ;
fhir:resourceReference [
fhir:reference [ fhir:v "Citation/COVID19IntensiveCareTreatmentGuidelineCitation" ]     ]
  ] ) ; # 
  fhir:action ( [
fhir:title [ fhir:v "Dexamethasone Application" ] ;
fhir:description [ fhir:v "Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/uv/cpg/CodeSystem/cpg-common-process"^^xsd:anyURI ] ;
fhir:code [ fhir:v "guideline-based-care" ]       ] )     ] ;
fhir:definition [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-ventilated-patients-dexamethasone-application-plan"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-ventilated-patients-dexamethasone-application-plan>     ]
  ] [
fhir:title [ fhir:v "No Dexamethasone Application" ] ;
fhir:description [ fhir:v "No Dexamethasone Application for non-ventilated COVID-19 patients" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/uv/cpg/CodeSystem/cpg-common-process"^^xsd:anyURI ] ;
fhir:code [ fhir:v "guideline-based-care" ]       ] )     ] ;
fhir:definition [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-non-ventilated-patients-no-dexamethasone-application-plan"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-non-ventilated-patients-no-dexamethasone-application-plan>     ]
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-plan-ventilated-patients> a fhir:PlanDefinition ;
  fhir:id [ fhir:v "COVID19VentilatedPatientsDexamethasoneApplicationPlan"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-plan"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-plan>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_COVID19VentilatedPatientsDexamethasoneApplicationPlan\"> </a><p class=\"res-header-id\"><b>Generated Narrative: PlanDefinition COVID19VentilatedPatientsDexamethasoneApplicationPlan</b></p><a name=\"COVID19VentilatedPatientsDexamethasoneApplicationPlan\"> </a><a name=\"hcCOVID19VentilatedPatientsDexamethasoneApplicationPlan\"> </a><a name=\"COVID19VentilatedPatientsDexamethasoneApplicationPlan-en-US\"> </a><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>partOf</b>: <a href=\"PlanDefinition-COVID19DexamethasoneApplication.html\">Dexamethasone Application</a></p><blockquote><p><b>Action Combination Method</b></p><ul><li>method: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method exactly}\">Exactly</span></li><li>threshold: 1</li></ul></blockquote><p><b>url</b>: <a href=\"PlanDefinition-COVID19VentilatedPatientsDexamethasoneApplicationPlan.html\">PlanDefinition Dexamethasone Application in ventilated COVID-19 patients</a></p><p><b>version</b>: 4.0</p><p><b>name</b>: Dexamethasone_Application</p><p><b>title</b>: Dexamethasone Application in ventilated COVID-19 patients</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/plan-definition-type eca-rule}\">ECA Rule</span></p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href=\"EvidenceVariable-PopulationCOVID19Ventilated.html\">Population_COVID19_Ventilated</a></p><p><b>date</b>: 2021-12-12</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients</p>\n</div><blockquote><p><b>action</b></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 432102000}\">Administration of substance (procedure)</span></p><p><b>definition</b>: <a href=\"Bundle-COVID19IntensiveCareTreatmentGuidelineBundle.html\">DexamethasoneApplicationActionOral</a></p></blockquote><blockquote><p><b>action</b></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 432102000}\">Administration of substance (procedure)</span></p><p><b>definition</b>: <a href=\"Bundle-COVID19IntensiveCareTreatmentGuidelineBundle.html\">DexamethasoneApplicationActionIntravenous</a></p></blockquote></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability"^^xsd:anyURI ] ;
fhir:value [ fhir:v "computable" ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel"^^xsd:anyURI ] ;
fhir:value [ fhir:v "structured" ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-partOf"^^xsd:anyURI ] ;
fhir:value [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-dexamethasone-recommendation"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-dexamethasone-recommendation>     ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "method"^^xsd:anyURI ] ;
fhir:value [
a fhir:CodeableConcept ;
        ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method"^^xsd:anyURI ] ;
fhir:code [ fhir:v "exactly" ]         ] )       ]     ] [
fhir:url [ fhir:v "threshold"^^xsd:anyURI ] ;
fhir:value [ fhir:v "1"^^xsd:positiveInteger ]     ] ) ;
fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-action-combination-method"^^xsd:anyURI ]
  ] ) ; # 
  fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-ventilated-patients-dexamethasone-application-plan"^^xsd:anyURI] ; # 
  fhir:version [ fhir:v "4.0"] ; # 
  fhir:name [ fhir:v "Dexamethasone_Application"] ; # 
  fhir:title [ fhir:v "Dexamethasone Application in ventilated COVID-19 patients"] ; # 
  fhir:type [
    ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/plan-definition-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "eca-rule" ]     ] )
  ] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:experimental [ fhir:v "true"^^xsd:boolean] ; # 
  fhir:subject [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_Ventilated"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_Ventilated>
  ] ; # 
  fhir:date [ fhir:v "2021-12-12"^^xsd:date] ; # 
  fhir:publisher [ fhir:v "CPGonEBMonFHIR"] ; # 
  fhir:description [ fhir:v "Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients"] ; # 
  fhir:action ( [
fhir:code [
      ( fhir:coding [
a sct:432102000 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "432102000" ] ;
fhir:display [ fhir:v "Administration of substance (procedure)" ]       ] )     ] ;
fhir:definition [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-oral"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-oral>     ]
  ] [
fhir:code [
      ( fhir:coding [
a sct:432102000 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "432102000" ] ;
fhir:display [ fhir:v "Administration of substance (procedure)" ]       ] )     ] ;
fhir:definition [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-intravenous"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-intravenous>     ]
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-plan-non-ventilated-patients> a fhir:PlanDefinition ;
  fhir:id [ fhir:v "COVID19NonVentilatedPatientsDexamethasoneApplicationPlan"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-plan"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-plan>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_COVID19NonVentilatedPatientsDexamethasoneApplicationPlan\"> </a><p class=\"res-header-id\"><b>Generated Narrative: PlanDefinition COVID19NonVentilatedPatientsDexamethasoneApplicationPlan</b></p><a name=\"COVID19NonVentilatedPatientsDexamethasoneApplicationPlan\"> </a><a name=\"hcCOVID19NonVentilatedPatientsDexamethasoneApplicationPlan\"> </a><a name=\"COVID19NonVentilatedPatientsDexamethasoneApplicationPlan-en-US\"> </a><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>partOf</b>: <a href=\"PlanDefinition-COVID19DexamethasoneApplication.html\">Dexamethasone Application</a></p><blockquote><p><b>Action Combination Method</b></p><ul><li>method: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method exactly}\">Exactly</span></li><li>threshold: 1</li></ul></blockquote><p><b>url</b>: <a href=\"PlanDefinition-COVID19NonVentilatedPatientsDexamethasoneApplicationPlan.html\">PlanDefinition No Dexamethasone Application for non-ventilated COVID-19 patients</a></p><p><b>version</b>: 4.0</p><p><b>name</b>: No_Dexamethasone_Application</p><p><b>title</b>: No Dexamethasone Application for non-ventilated COVID-19 patients</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/plan-definition-type eca-rule}\">ECA Rule</span></p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href=\"EvidenceVariable-PopulationCOVID19NonVentilated.html\">Population_COVID19_NonVentilated</a></p><p><b>date</b>: 2021-12-12</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>No Dexamethasone Application for non-ventilated COVID19 patients</p>\n</div><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 432102000}\">Administration of substance (procedure)</span></td><td><a href=\"Bundle-COVID19IntensiveCareTreatmentGuidelineBundle.html\">NoDexamethasoneApplicationActivity</a></td></tr></table></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability"^^xsd:anyURI ] ;
fhir:value [ fhir:v "computable" ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel"^^xsd:anyURI ] ;
fhir:value [ fhir:v "structured" ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-partOf"^^xsd:anyURI ] ;
fhir:value [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-dexamethasone-recommendation"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-dexamethasone-recommendation>     ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "method"^^xsd:anyURI ] ;
fhir:value [
a fhir:CodeableConcept ;
        ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method"^^xsd:anyURI ] ;
fhir:code [ fhir:v "exactly" ]         ] )       ]     ] [
fhir:url [ fhir:v "threshold"^^xsd:anyURI ] ;
fhir:value [ fhir:v "1"^^xsd:positiveInteger ]     ] ) ;
fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-action-combination-method"^^xsd:anyURI ]
  ] ) ; # 
  fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-non-ventilated-patients-no-dexamethasone-application-plan"^^xsd:anyURI] ; # 
  fhir:version [ fhir:v "4.0"] ; # 
  fhir:name [ fhir:v "No_Dexamethasone_Application"] ; # 
  fhir:title [ fhir:v "No Dexamethasone Application for non-ventilated COVID-19 patients"] ; # 
  fhir:type [
    ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/plan-definition-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "eca-rule" ]     ] )
  ] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:experimental [ fhir:v "true"^^xsd:boolean] ; # 
  fhir:subject [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_NonVentilated"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_NonVentilated>
  ] ; # 
  fhir:date [ fhir:v "2021-12-12"^^xsd:date] ; # 
  fhir:publisher [ fhir:v "CPGonEBMonFHIR"] ; # 
  fhir:description [ fhir:v "No Dexamethasone Application for non-ventilated COVID19 patients"] ; # 
  fhir:action ( [
fhir:code [
      ( fhir:coding [
a sct:432102000 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "432102000" ] ;
fhir:display [ fhir:v "Administration of substance (procedure)" ]       ] )     ] ;
fhir:definition [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/no-dexamethasone-application"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/no-dexamethasone-application>     ]
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-oral> a fhir:ActivityDefinition ;
  fhir:id [ fhir:v "DexamethasoneApplicationActionOral"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_DexamethasoneApplicationActionOral\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ActivityDefinition DexamethasoneApplicationActionOral</b></p><a name=\"DexamethasoneApplicationActionOral\"> </a><a name=\"hcDexamethasoneApplicationActionOral\"> </a><a name=\"DexamethasoneApplicationActionOral-en-US\"> </a><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <a href=\"ActivityDefinition-DexamethasoneApplicationActionOral.html\">ActivityDefinition DexamethasoneApplicationActionOral</a></p><p><b>version</b>: 1.0</p><p><b>name</b>: DexamethasoneApplicationActionOral</p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <span title=\"Codes:{http://hl7.org/fhir/fhir-types Patient}\">Patient</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>Application of Dexamethasone: 6 mg once per day for 10 days (oral route)</p>\n</div><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 432102000}\">Administration of substance (procedure)</span></p><p><b>product</b>: <span title=\"Codes:{http://snomed.info/sct 372584003}, {http://fhir.de/CodeSystem/bfarm/atc C05AA09}\">Dexamethasone (substance)</span></p><blockquote><p><b>dosage</b></p><p><b>timing</b>: Count 10  times, Duration 10days , Once per 1 days</p><p><b>route</b>: <span title=\"Codes:{http://snomed.info/sct 26643006}\">Oral route</span></p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td><td><b>Rate[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>6 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg = 'mg')</span></td><td>1 /d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code/d = '/d')</span></td></tr></table></blockquote></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability"^^xsd:anyURI ] ;
fhir:value [ fhir:v "computable" ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel"^^xsd:anyURI ] ;
fhir:value [ fhir:v "structured" ]
  ] ) ; # 
  fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-oral"^^xsd:anyURI] ; # 
  fhir:version [ fhir:v "1.0"] ; # 
  fhir:name [ fhir:v "DexamethasoneApplicationActionOral"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:experimental [ fhir:v "true"^^xsd:boolean] ; # 
  fhir:subject [
a fhir:CodeableConcept ;
    ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/fhir-types"^^xsd:anyURI ] ;
fhir:code [ fhir:v "Patient" ]     ] )
  ] ; # 
  fhir:publisher [ fhir:v "CPGonEBMonFHIR"] ; # 
  fhir:description [ fhir:v "Application of Dexamethasone: 6 mg once per day for 10 days (oral route)"] ; # 
  fhir:kind [ fhir:v "MedicationRequest"] ; # 
  fhir:code [
    ( fhir:coding [
a sct:432102000 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "432102000" ] ;
fhir:display [ fhir:v "Administration of substance (procedure)" ]     ] )
  ] ; # 
  fhir:product [
a fhir:CodeableConcept ;
    ( fhir:coding [
a sct:372584003 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "372584003" ] ;
fhir:display [ fhir:v "Dexamethasone (substance)" ]     ] [
fhir:system [ fhir:v "http://fhir.de/CodeSystem/bfarm/atc"^^xsd:anyURI ] ;
fhir:code [ fhir:v "C05AA09" ] ;
fhir:display [ fhir:v "Dexamethason" ]     ] )
  ] ; # 
  fhir:dosage ( [
fhir:timing [
fhir:repeat [
fhir:count [ fhir:v "10"^^xsd:positiveInteger ] ;
fhir:duration [ fhir:v "10"^^xsd:decimal ] ;
fhir:durationUnit [ fhir:v "d" ] ;
fhir:frequency [ fhir:v "1"^^xsd:positiveInteger ] ;
fhir:period [ fhir:v "1"^^xsd:decimal ] ;
fhir:periodUnit [ fhir:v "d" ]       ]     ] ;
fhir:route [
      ( fhir:coding [
a sct:26643006 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "26643006" ] ;
fhir:display [ fhir:v "Oral route" ]       ] )     ] ;
    ( fhir:doseAndRate [
fhir:dose [
a fhir:Quantity ;
fhir:value [ fhir:v "6"^^xsd:decimal ] ;
fhir:unit [ fhir:v "mg" ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "mg" ]       ] ;
fhir:rate [
a fhir:Quantity ;
fhir:value [ fhir:v "1"^^xsd:decimal ] ;
fhir:unit [ fhir:v "/d" ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "/d" ]       ]     ] )
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-intravenous> a fhir:ActivityDefinition ;
  fhir:id [ fhir:v "DexamethasoneApplicationActionIntravenous"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_DexamethasoneApplicationActionIntravenous\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ActivityDefinition DexamethasoneApplicationActionIntravenous</b></p><a name=\"DexamethasoneApplicationActionIntravenous\"> </a><a name=\"hcDexamethasoneApplicationActionIntravenous\"> </a><a name=\"DexamethasoneApplicationActionIntravenous-en-US\"> </a><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <a href=\"ActivityDefinition-DexamethasoneApplicationActionIntravenous.html\">ActivityDefinition DexamethasoneApplicationActionIntravenous</a></p><p><b>version</b>: 1.0</p><p><b>name</b>: DexamethasoneApplicationActionIntravenous</p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <span title=\"Codes:{http://hl7.org/fhir/fhir-types Patient}\">Patient</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>Application of Dexamethasone: 6 mg once per day for 10 days (intravenous route)</p>\n</div><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 432102000}\">Administration of substance (procedure)</span></p><p><b>product</b>: <span title=\"Codes:{http://snomed.info/sct 372584003}, {http://fhir.de/CodeSystem/bfarm/atc C05AA09}\">Dexamethasone (substance)</span></p><blockquote><p><b>dosage</b></p><p><b>timing</b>: Count 10  times, Duration 10days , Once per 1 days</p><p><b>route</b>: <span title=\"Codes:{http://snomed.info/sct 47625008}\">Intravenous route</span></p><h3>DoseAndRates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Dose[x]</b></td><td><b>Rate[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>6 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg = 'mg')</span></td><td>1 /d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code/d = '/d')</span></td></tr></table></blockquote></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability"^^xsd:anyURI ] ;
fhir:value [ fhir:v "computable" ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel"^^xsd:anyURI ] ;
fhir:value [ fhir:v "structured" ]
  ] ) ; # 
  fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-intravenous"^^xsd:anyURI] ; # 
  fhir:version [ fhir:v "1.0"] ; # 
  fhir:name [ fhir:v "DexamethasoneApplicationActionIntravenous"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:experimental [ fhir:v "true"^^xsd:boolean] ; # 
  fhir:subject [
a fhir:CodeableConcept ;
    ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/fhir-types"^^xsd:anyURI ] ;
fhir:code [ fhir:v "Patient" ]     ] )
  ] ; # 
  fhir:publisher [ fhir:v "CPGonEBMonFHIR"] ; # 
  fhir:description [ fhir:v "Application of Dexamethasone: 6 mg once per day for 10 days (intravenous route)"] ; # 
  fhir:kind [ fhir:v "MedicationRequest"] ; # 
  fhir:code [
    ( fhir:coding [
a sct:432102000 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "432102000" ] ;
fhir:display [ fhir:v "Administration of substance (procedure)" ]     ] )
  ] ; # 
  fhir:product [
a fhir:CodeableConcept ;
    ( fhir:coding [
a sct:372584003 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "372584003" ] ;
fhir:display [ fhir:v "Dexamethasone (substance)" ]     ] [
fhir:system [ fhir:v "http://fhir.de/CodeSystem/bfarm/atc"^^xsd:anyURI ] ;
fhir:code [ fhir:v "C05AA09" ] ;
fhir:display [ fhir:v "Dexamethason" ]     ] )
  ] ; # 
  fhir:dosage ( [
fhir:timing [
fhir:repeat [
fhir:count [ fhir:v "10"^^xsd:positiveInteger ] ;
fhir:duration [ fhir:v "10"^^xsd:decimal ] ;
fhir:durationUnit [ fhir:v "d" ] ;
fhir:frequency [ fhir:v "1"^^xsd:positiveInteger ] ;
fhir:period [ fhir:v "1"^^xsd:decimal ] ;
fhir:periodUnit [ fhir:v "d" ]       ]     ] ;
fhir:route [
      ( fhir:coding [
a sct:47625008 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "47625008" ] ;
fhir:display [ fhir:v "Intravenous route" ]       ] )     ] ;
    ( fhir:doseAndRate [
fhir:dose [
a fhir:Quantity ;
fhir:value [ fhir:v "6"^^xsd:decimal ] ;
fhir:unit [ fhir:v "mg" ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "mg" ]       ] ;
fhir:rate [
a fhir:Quantity ;
fhir:value [ fhir:v "1"^^xsd:decimal ] ;
fhir:unit [ fhir:v "/d" ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "/d" ]       ]     ] )
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-no-application> a fhir:ActivityDefinition ;
  fhir:id [ fhir:v "NoDexamethasoneApplication"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_NoDexamethasoneApplication\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ActivityDefinition NoDexamethasoneApplication</b></p><a name=\"NoDexamethasoneApplication\"> </a><a name=\"hcNoDexamethasoneApplication\"> </a><a name=\"NoDexamethasoneApplication-en-US\"> </a><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <a href=\"ActivityDefinition-NoDexamethasoneApplication.html\">ActivityDefinition NoDexamethasoneApplicationActivity</a></p><p><b>version</b>: 1.0</p><p><b>name</b>: NoDexamethasoneApplicationActivity</p><p><b>status</b>: Active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <span title=\"Codes:{http://hl7.org/fhir/fhir-types Patient}\">Patient</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: </p><div><p>No Application of Dexamethasone</p>\n</div><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 432102000}\">Administration of substance (procedure)</span></p><p><b>doNotPerform</b>: true</p><p><b>product</b>: <span title=\"Codes:{http://snomed.info/sct 372584003}, {http://fhir.de/CodeSystem/bfarm/atc C05AA09}\">Dexamethasone (substance)</span></p></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability"^^xsd:anyURI ] ;
fhir:value [ fhir:v "computable" ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel"^^xsd:anyURI ] ;
fhir:value [ fhir:v "structured" ]
  ] ) ; # 
  fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/no-dexamethasone-application"^^xsd:anyURI] ; # 
  fhir:version [ fhir:v "1.0"] ; # 
  fhir:name [ fhir:v "NoDexamethasoneApplicationActivity"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:experimental [ fhir:v "true"^^xsd:boolean] ; # 
  fhir:subject [
a fhir:CodeableConcept ;
    ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/fhir-types"^^xsd:anyURI ] ;
fhir:code [ fhir:v "Patient" ]     ] )
  ] ; # 
  fhir:publisher [ fhir:v "CPGonEBMonFHIR"] ; # 
  fhir:description [ fhir:v "No Application of Dexamethasone"] ; # 
  fhir:kind [ fhir:v "MedicationRequest"] ; # 
  fhir:code [
    ( fhir:coding [
a sct:432102000 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "432102000" ] ;
fhir:display [ fhir:v "Administration of substance (procedure)" ]     ] )
  ] ; # 
  fhir:doNotPerform [ fhir:v "true"^^xsd:boolean] ; # 
  fhir:product [
a fhir:CodeableConcept ;
    ( fhir:coding [
a sct:372584003 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "372584003" ] ;
fhir:display [ fhir:v "Dexamethasone (substance)" ]     ] [
fhir:system [ fhir:v "http://fhir.de/CodeSystem/bfarm/atc"^^xsd:anyURI ] ;
fhir:code [ fhir:v "C05AA09" ] ;
fhir:display [ fhir:v "Dexamethason" ]     ] )
  ] . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-citation> a fhir:Citation ;
  fhir:id [ fhir:v "DexamethasoneRecommendationCitation"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-citation"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-citation>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Citation_DexamethasoneRecommendationCitation\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Citation DexamethasoneRecommendationCitation</b></p><a name=\"DexamethasoneRecommendationCitation\"> </a><a name=\"hcDexamethasoneRecommendationCitation\"> </a><a name=\"DexamethasoneRecommendationCitation-en-US\"> </a><p><b>name</b>: DexamethasoneRecommendationCitation</p><p><b>status</b>: Active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: <code>https://api.magicapp.org/api/v1/recommendations</code>/98398</p><h3>Versions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Value</b></td></tr><tr><td style=\"display: none\">*</td><td>v4.0</td></tr></table><p><b>currentState</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-status-type active}\">Active</span></p><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td><div><p>Steroide</p>\n</div></td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type publication-type}\">Publication Type</span></td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system guideline-recommendation}\">Clinical practice guideline recommendation</span></td></tr></table></blockquote></div>"
  ] ; # 
  fhir:name [ fhir:v "DexamethasoneRecommendationCitation"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:citedArtifact [
    ( fhir:identifier [
fhir:system [ fhir:v "https://api.magicapp.org/api/v1/recommendations"^^xsd:anyURI ] ;
fhir:value [ fhir:v "98398" ]     ] ) ;
fhir:version [
fhir:value [ fhir:v "v4.0" ]     ] ;
    ( fhir:currentState [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-status-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "active" ] ;
fhir:display [ fhir:v "Active" ]       ] )     ] ) ;
    ( fhir:title [
fhir:text [ fhir:v "Steroide" ]     ] ) ;
    ( fhir:classification [
fhir:type [
        ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "publication-type" ] ;
fhir:display [ fhir:v "Publication Type" ]         ] )       ] ;
      ( fhir:classifier [
        ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "guideline-recommendation" ] ;
fhir:display [ fhir:v "Clinical practice guideline recommendation" ]         ] )       ] )     ] )
  ] . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-ventilated> a fhir:EvidenceVariable ;
  fhir:id [ fhir:v "PopulationCOVID19Ventilated"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_PopulationCOVID19Ventilated\"> </a><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable PopulationCOVID19Ventilated</b></p><a name=\"PopulationCOVID19Ventilated\"> </a><a name=\"hcPopulationCOVID19Ventilated\"> </a><a name=\"PopulationCOVID19Ventilated-en-US\"> </a><p><b>url</b>: <a href=\"EvidenceVariable-PopulationCOVID19Ventilated.html\">EvidenceVariable Population_COVID19_Ventilated</a></p><p><b>identifier</b>: <code>https://www.ceosys.de</code>/Ventilated</p><p><b>name</b>: Population_COVID19_Ventilated</p><p><b>status</b>: Active</p><p><b>description</b>: </p><div><p>Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, Ventilated</p>\n</div><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: covid19</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 840539006}\">Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>exclude</b>: false</p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: Any of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: oxy-administration-nasal-cannula</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 371907003}\">Oxygen administration by nasal cannula (procedure)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  coded = 'd')</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: noninvasive-ventilation</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 428311008}\">Non-invasive ventilation (regime/therapy)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  coded = 'd')</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: artificial-respiration</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 40617009}\">Artificial ventilation (regime/therapy)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  coded = 'd')</span></td></tr></table></blockquote></blockquote></blockquote></div>"
  ] ; # 
  fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_Ventilated"^^xsd:anyURI] ; # 
  fhir:identifier ( [
fhir:system [ fhir:v "https://www.ceosys.de"^^xsd:anyURI ] ;
fhir:value [ fhir:v "Ventilated" ]
  ] ) ; # 
  fhir:name [ fhir:v "Population_COVID19_Ventilated"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:description [ fhir:v "Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, Ventilated"] ; # 
  fhir:characteristic ( [
fhir:linkId [ fhir:v "covid19" ] ;
fhir:definitionByTypeAndValue [
fhir:type [
        ( fhir:coding [
a sct:404684003 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "404684003" ] ;
fhir:display [ fhir:v "Clinical finding (finding)" ]         ] )       ] ;
fhir:value [
a fhir:CodeableConcept ;
        ( fhir:coding [
a sct:840539006 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "840539006" ] ;
fhir:display [ fhir:v "Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)" ]         ] )       ]     ]
  ] [
fhir:exclude [ fhir:v "false"^^xsd:boolean ] ;
fhir:definitionByCombination [
fhir:code [ fhir:v "any-of" ] ;
      ( fhir:characteristic [
fhir:linkId [ fhir:v "oxy-administration-nasal-cannula" ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ] ;
fhir:definitionByTypeAndValue [
fhir:type [
            ( fhir:coding [
a sct:71388002 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "71388002" ] ;
fhir:display [ fhir:v "Procedure (procedure)" ]             ] )           ] ;
fhir:value [
a fhir:CodeableConcept ;
            ( fhir:coding [
a sct:371907003 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "371907003" ] ;
fhir:display [ fhir:v "Oxygen administration by nasal cannula (procedure)" ]             ] )           ]         ] ;
        ( fhir:timeFromEvent [
fhir:event [ fhir:v "covid19" ] ;
fhir:quantity [
fhir:value [ fhir:v "0"^^xsd:decimal ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "d" ]           ]         ] )       ] [
fhir:linkId [ fhir:v "noninvasive-ventilation" ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ] ;
fhir:definitionByTypeAndValue [
fhir:type [
            ( fhir:coding [
a sct:71388002 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "71388002" ] ;
fhir:display [ fhir:v "Procedure (procedure)" ]             ] )           ] ;
fhir:value [
a fhir:CodeableConcept ;
            ( fhir:coding [
a sct:428311008 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "428311008" ] ;
fhir:display [ fhir:v "Non-invasive ventilation (regime/therapy)" ]             ] )           ]         ] ;
        ( fhir:timeFromEvent [
fhir:event [ fhir:v "covid19" ] ;
fhir:quantity [
fhir:value [ fhir:v "0"^^xsd:decimal ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "d" ]           ]         ] )       ] [
fhir:linkId [ fhir:v "artificial-respiration" ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ] ;
fhir:definitionByTypeAndValue [
fhir:type [
            ( fhir:coding [
a sct:71388002 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "71388002" ] ;
fhir:display [ fhir:v "Procedure (procedure)" ]             ] )           ] ;
fhir:value [
a fhir:CodeableConcept ;
            ( fhir:coding [
a sct:40617009 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "40617009" ] ;
fhir:display [ fhir:v "Artificial ventilation (regime/therapy)" ]             ] )           ]         ] ;
        ( fhir:timeFromEvent [
fhir:event [ fhir:v "covid19" ] ;
fhir:quantity [
fhir:value [ fhir:v "0"^^xsd:decimal ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "d" ]           ]         ] )       ] )     ]
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-non-ventilated> a fhir:EvidenceVariable ;
  fhir:id [ fhir:v "PopulationCOVID19NonVentilated"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_PopulationCOVID19NonVentilated\"> </a><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable PopulationCOVID19NonVentilated</b></p><a name=\"PopulationCOVID19NonVentilated\"> </a><a name=\"hcPopulationCOVID19NonVentilated\"> </a><a name=\"PopulationCOVID19NonVentilated-en-US\"> </a><p><b>url</b>: <a href=\"EvidenceVariable-PopulationCOVID19NonVentilated.html\">EvidenceVariable Population_COVID19_NonVentilated</a></p><p><b>identifier</b>: <code>https://www.ceosys.de</code>/NonVentilated</p><p><b>name</b>: Population_COVID19_NonVentilated</p><p><b>status</b>: Active</p><p><b>description</b>: </p><div><p>Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, not ventilated</p>\n</div><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: covid19</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 840539006}\">Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>exclude</b>: true</p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: Any of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: oxy-administration-nasal-cannula</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 371907003}\">Oxygen administration by nasal cannula (procedure)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  coded = 'd')</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: noninvasive-ventilation</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 428311008}\">Non-invasive ventilation (regime/therapy)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  coded = 'd')</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: artificial-respiration</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 71388002}\">Procedure (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 40617009}\">Artificial ventilation (regime/therapy)</span></td></tr></table><h3>TimeFromEvents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Event[x]</b></td><td><b>Quantity</b></td></tr><tr><td style=\"display: none\">*</td><td>covid19</td><td>0 d<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  coded = 'd')</span></td></tr></table></blockquote></blockquote></blockquote></div>"
  ] ; # 
  fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_NonVentilated"^^xsd:anyURI] ; # 
  fhir:identifier ( [
fhir:system [ fhir:v "https://www.ceosys.de"^^xsd:anyURI ] ;
fhir:value [ fhir:v "NonVentilated" ]
  ] ) ; # 
  fhir:name [ fhir:v "Population_COVID19_NonVentilated"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:description [ fhir:v "Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, not ventilated"] ; # 
  fhir:characteristic ( [
fhir:linkId [ fhir:v "covid19" ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ] ;
fhir:definitionByTypeAndValue [
fhir:type [
        ( fhir:coding [
a sct:404684003 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "404684003" ] ;
fhir:display [ fhir:v "Clinical finding (finding)" ]         ] )       ] ;
fhir:value [
a fhir:CodeableConcept ;
        ( fhir:coding [
a sct:840539006 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "840539006" ] ;
fhir:display [ fhir:v "Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)" ]         ] )       ]     ]
  ] [
fhir:exclude [ fhir:v "true"^^xsd:boolean ] ;
fhir:definitionByCombination [
fhir:code [ fhir:v "any-of" ] ;
      ( fhir:characteristic [
fhir:linkId [ fhir:v "oxy-administration-nasal-cannula" ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ] ;
fhir:definitionByTypeAndValue [
fhir:type [
            ( fhir:coding [
a sct:71388002 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "71388002" ] ;
fhir:display [ fhir:v "Procedure (procedure)" ]             ] )           ] ;
fhir:value [
a fhir:CodeableConcept ;
            ( fhir:coding [
a sct:371907003 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "371907003" ] ;
fhir:display [ fhir:v "Oxygen administration by nasal cannula (procedure)" ]             ] )           ]         ] ;
        ( fhir:timeFromEvent [
fhir:event [ fhir:v "covid19" ] ;
fhir:quantity [
fhir:value [ fhir:v "0"^^xsd:decimal ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "d" ]           ]         ] )       ] [
fhir:linkId [ fhir:v "noninvasive-ventilation" ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ] ;
fhir:definitionByTypeAndValue [
fhir:type [
            ( fhir:coding [
a sct:71388002 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "71388002" ] ;
fhir:display [ fhir:v "Procedure (procedure)" ]             ] )           ] ;
fhir:value [
a fhir:CodeableConcept ;
            ( fhir:coding [
a sct:428311008 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "428311008" ] ;
fhir:display [ fhir:v "Non-invasive ventilation (regime/therapy)" ]             ] )           ]         ] ;
        ( fhir:timeFromEvent [
fhir:event [ fhir:v "covid19" ] ;
fhir:quantity [
fhir:value [ fhir:v "0"^^xsd:decimal ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "d" ]           ]         ] )       ] [
fhir:linkId [ fhir:v "artificial-respiration" ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ] ;
fhir:definitionByTypeAndValue [
fhir:type [
            ( fhir:coding [
a sct:71388002 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "71388002" ] ;
fhir:display [ fhir:v "Procedure (procedure)" ]             ] )           ] ;
fhir:value [
a fhir:CodeableConcept ;
            ( fhir:coding [
a sct:40617009 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "40617009" ] ;
fhir:display [ fhir:v "Artificial ventilation (regime/therapy)" ]             ] )           ]         ] ;
        ( fhir:timeFromEvent [
fhir:event [ fhir:v "covid19" ] ;
fhir:quantity [
fhir:value [ fhir:v "0"^^xsd:decimal ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "d" ]           ]         ] )       ] )     ]
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/rating-outcome-mortality> a fhir:ArtifactAssessment ;
  fhir:id [ fhir:v "DexamethasoneRatingOutcomeMortality"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/certainty-of-evidence-rating"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/certainty-of-evidence-rating>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ArtifactAssessment_DexamethasoneRatingOutcomeMortality\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ArtifactAssessment DexamethasoneRatingOutcomeMortality</b></p><a name=\"DexamethasoneRatingOutcomeMortality\"> </a><a name=\"hcDexamethasoneRatingOutcomeMortality\"> </a><a name=\"DexamethasoneRatingOutcomeMortality-en-US\"> </a><p><b>ArtifactAssessment Version</b>: v4.0</p><p><b>ArtifactAssessment Publication Status</b>: active</p><p><b>date</b>: 2020-01-03</p><p><b>artifact</b>: <a href=\"Evidence-DexamethasoneOutcomeMortality.html\">Evidence ExampleOutcomeEvidence</a></p><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Overall}\">Overall certainty</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating moderate}\">Moderate quality</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system clinical-importance}\">Clinical Importance</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-clinical-importance 9}\">Critical</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type RiskOfBias}\">Risk of bias</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating serious-concern}\">serious concern</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Inconsistency}\">Inconsistency</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Indirectness}\">Indirectness</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type Imprecision}\">Imprecision</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-type PublicationBias}\">Publication bias</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/certainty-rating no-concern}\">no serious concern</span></p></blockquote></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-version"^^xsd:anyURI ] ;
fhir:value [ fhir:v "v4.0" ]
  ] [
fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-publication-status"^^xsd:anyURI ] ;
fhir:value [ fhir:v "active" ]
  ] ) ; # 
  fhir:date [ fhir:v "2020-01-03"^^xsd:date] ; # 
  fhir:artifact [
a fhir:Reference ;
fhir:reference [ fhir:v "Evidence/DexamethasoneOutcomeMortality" ]
  ] ; # 
  fhir:content ( [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "Overall" ] ;
fhir:display [ fhir:v "Overall certainty" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
fhir:code [ fhir:v "moderate" ] ;
fhir:display [ fhir:v "Moderate quality" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "clinical-importance" ] ;
fhir:display [ fhir:v "Clinical Importance" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-clinical-importance"^^xsd:anyURI ] ;
fhir:code [ fhir:v "9" ] ;
fhir:display [ fhir:v "Critical" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "RiskOfBias" ] ;
fhir:display [ fhir:v "Risk of bias" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
fhir:code [ fhir:v "serious-concern" ] ;
fhir:display [ fhir:v "serious concern" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "Inconsistency" ] ;
fhir:display [ fhir:v "Inconsistency" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
fhir:code [ fhir:v "no-concern" ] ;
fhir:display [ fhir:v "no serious concern" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "Indirectness" ] ;
fhir:display [ fhir:v "Indirectness" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
fhir:code [ fhir:v "no-concern" ] ;
fhir:display [ fhir:v "no serious concern" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "Imprecision" ] ;
fhir:display [ fhir:v "Imprecision" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
fhir:code [ fhir:v "no-concern" ] ;
fhir:display [ fhir:v "no serious concern" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "PublicationBias" ] ;
fhir:display [ fhir:v "Publication bias" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/certainty-rating"^^xsd:anyURI ] ;
fhir:code [ fhir:v "no-concern" ] ;
fhir:display [ fhir:v "no serious concern" ]       ] )     ] )
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/outcome-mortality> a fhir:Evidence ;
  fhir:id [ fhir:v "DexamethasoneOutcomeMortality"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-evidence-synthesis"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-evidence-synthesis>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Evidence_DexamethasoneOutcomeMortality\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Evidence DexamethasoneOutcomeMortality</b></p><a name=\"DexamethasoneOutcomeMortality\"> </a><a name=\"hcDexamethasoneOutcomeMortality\"> </a><a name=\"DexamethasoneOutcomeMortality-en-US\"> </a><p><b>name</b>: ExampleOutcomeEvidence</p><p><b>status</b>: Active</p><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>Citation</td><td><a href=\"Citation-SystemicCorticosteroidsForTheTreatmentOfCOVID19.html\">Citation SystemicCorticosteroidsForTheTreatmentOfCOVID19</a></td></tr></table><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/variable-role population}\">population</span></p><p><b>observed</b>: <a href=\"Group-StudyCohortCorticosteroidsCOVID19.html\">Group StudyCohortCriteriaSystemicCorticosteroidsCOVID19</a></p><p><b>intended</b>: <a href=\"EvidenceVariable-StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19.html\">EvidenceVariable StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/variable-role measuredVariable}\">measured variable</span></p><p><b>observed</b>: <a href=\"EvidenceVariable-OutcomeAllCauseMortality.html\">EvidenceVariable AllCauseMortality</a></p></blockquote><p><b>synthesisType</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/synthesis-type NotApplicable}\">not applicable</span></p><blockquote><p><b>statistic</b></p><p><b>description</b>: </p><div><p>Relative effect of intervention vs. comparator</p>\n</div><p><b>statisticType</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/statistic-type C93152}\">Relative Risk</span></p><p><b>quantity</b>: 0.89</p><h3>SampleSizes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>NumberOfStudies</b></td><td><b>NumberOfParticipants</b></td></tr><tr><td style=\"display: none\">*</td><td>9</td><td>7930</td></tr></table><h3>AttributeEstimates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/attribute-estimate-type C53324}\">Confidence interval</span></td><td>0.95</td><td>0.8-1</td></tr></table></blockquote><blockquote><p><b>statistic</b></p><p><b>description</b>: </p><div><p>Baseline risk/result in the comparison group</p>\n</div><p><b>statisticType</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/statistic-type C16726}\">Incidence</span></p><p><b>quantity</b>: 245 1/1000<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code1/1000 = '1/1000')</span></p></blockquote></div>"
  ] ; # 
  fhir:name [ fhir:v "ExampleOutcomeEvidence"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:relatedArtifact ( [
fhir:type [ fhir:v "citation" ] ;
fhir:resourceReference [
fhir:reference [ fhir:v "Citation/SystemicCorticosteroidsForTheTreatmentOfCOVID19" ]     ]
  ] ) ; # 
  fhir:variableDefinition ( [
fhir:variableRole [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/variable-role"^^xsd:anyURI ] ;
fhir:code [ fhir:v "population" ]       ] )     ] ;
fhir:observed [
fhir:reference [ fhir:v "Group/StudyCohortCorticosteroidsCOVID19" ]     ] ;
fhir:intended [
fhir:reference [ fhir:v "EvidenceVariable/StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19" ]     ]
  ] [
fhir:variableRole [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/variable-role"^^xsd:anyURI ] ;
fhir:code [ fhir:v "measuredVariable" ]       ] )     ] ;
fhir:observed [
fhir:reference [ fhir:v "EvidenceVariable/OutcomeAllCauseMortality" ]     ]
  ] ) ; # 
  fhir:synthesisType [
    ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/synthesis-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "NotApplicable" ]     ] )
  ] ; # 
  fhir:statistic ( [
fhir:description [ fhir:v "Relative effect of intervention vs. comparator" ] ;
fhir:statisticType [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/statistic-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "C93152" ] ;
fhir:display [ fhir:v "Relative Risk" ]       ] )     ] ;
fhir:quantity [
fhir:value [ fhir:v "0.89"^^xsd:decimal ]     ] ;
fhir:sampleSize [
fhir:numberOfStudies [ fhir:v "9"^^xsd:nonNegativeInteger ] ;
fhir:numberOfParticipants [ fhir:v "7930"^^xsd:nonNegativeInteger ]     ] ;
    ( fhir:attributeEstimate [
fhir:type [
        ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/attribute-estimate-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "C53324" ] ;
fhir:display [ fhir:v "Confidence interval" ]         ] )       ] ;
fhir:level [ fhir:v "0.95"^^xsd:decimal ] ;
fhir:range [
fhir:low [
fhir:value [ fhir:v "0.8"^^xsd:decimal ]         ] ;
fhir:high [
fhir:value [ fhir:v "1"^^xsd:decimal ]         ]       ]     ] )
  ] [
fhir:description [ fhir:v "Baseline risk/result in the comparison group" ] ;
fhir:statisticType [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/statistic-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "C16726" ] ;
fhir:display [ fhir:v "Incidence" ]       ] )     ] ;
fhir:quantity [
fhir:value [ fhir:v "245"^^xsd:decimal ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "1/1000" ]     ]
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/study-eligibility-criteria> a fhir:EvidenceVariable ;
  fhir:id [ fhir:v "StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-eligibility-criteria"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-eligibility-criteria>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19\"> </a><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19</b></p><a name=\"StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19\"> </a><a name=\"hcStudyEligibilityCriteriaSystemicCorticosteroidsCOVID19\"> </a><a name=\"StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19-en-US\"> </a><p><b>name</b>: StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19</p><p><b>status</b>: Active</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 840539006}\">Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)</span></td></tr></table></blockquote></div>"
  ] ; # 
  fhir:name [ fhir:v "StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:characteristic ( [
fhir:definitionByTypeAndValue [
fhir:type [
        ( fhir:coding [
a sct:404684003 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "404684003" ] ;
fhir:display [ fhir:v "Clinical finding (finding)" ]         ] )       ] ;
fhir:value [
a fhir:CodeableConcept ;
        ( fhir:coding [
a sct:840539006 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "840539006" ] ;
fhir:display [ fhir:v "Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)" ]         ] )       ]     ]
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/outcome-all-cause-mortality> a fhir:EvidenceVariable ;
  fhir:id [ fhir:v "OutcomeAllCauseMortality"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-definition"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-definition>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_OutcomeAllCauseMortality\"> </a><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable OutcomeAllCauseMortality</b></p><a name=\"OutcomeAllCauseMortality\"> </a><a name=\"hcOutcomeAllCauseMortality\"> </a><a name=\"OutcomeAllCauseMortality-en-US\"> </a><p><b>name</b>: AllCauseMortality</p><p><b>status</b>: Active</p><h3>Characteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Exclude</b></td><td><b>DefinitionCodeableConcept</b></td></tr><tr><td style=\"display: none\">*</td><td>false</td><td><span title=\"Codes:{http://snomed.info/sct 409651001}\">Mortality rate (observable entity)</span></td></tr></table><p><b>handling</b>: dichotomous variable</p></div>"
  ] ; # 
  fhir:name [ fhir:v "AllCauseMortality"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:characteristic ( [
fhir:exclude [ fhir:v "false"^^xsd:boolean ] ;
fhir:definitionCodeableConcept [
      ( fhir:coding [
a sct:409651001 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "409651001" ] ;
fhir:display [ fhir:v "Mortality rate (observable entity)" ]       ] )     ]
  ] ) ; # 
  fhir:handling [ fhir:v "dichotomous"] . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-justification> a fhir:ArtifactAssessment ;
  fhir:id [ fhir:v "DexamethasoneRecommendationJustification"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-justification"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-justification>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ArtifactAssessment_DexamethasoneRecommendationJustification\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ArtifactAssessment DexamethasoneRecommendationJustification</b></p><a name=\"DexamethasoneRecommendationJustification\"> </a><a name=\"hcDexamethasoneRecommendationJustification\"> </a><a name=\"DexamethasoneRecommendationJustification-en-US\"> </a><p><b>ArtifactAssessment Version</b>: v4.0</p><p><b>ArtifactAssessment Publication Status</b>: active</p><p><b>date</b>: 2020-01-03</p><p><b>artifact</b>: <a href=\"PlanDefinition-COVID19VentilatedPatientsDexamethasoneApplicationPlan.html\">PlanDefinition Dexamethasone Application in ventilated COVID-19 patients</a></p><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system strength}\">Strength of recommendation</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-cs-recommendation-strength strong-for}\">Strong for an intervention</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system consensus}\">Consensus</span></p><p><b>classifier</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/recommendation-strength strong}\">Strong</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type preference-and-values}\">Preference and values</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating factor-not-considered}\">Factor not considered</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type resources}\">Resources</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating no-important-issues}\">No important issues</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type acceptability}\">Acceptability</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating factor-not-considered}\">Factor not considered</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Rating</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type feasibility}\">Feasibility</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating factor-not-considered}\">Factor not considered</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Container</p><p><b>type</b>: <span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system certainty-of-evidence-rating}\">Certainty of evidence rating</span></p><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>Justification</td><td><span title=\"Codes:{https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system certainty-of-evidence-rating}\">Certainty of evidence rating</span></td><td><a href=\"ArtifactAssessment-DexamethasoneRatingOutcomeMortality.html\">ArtifactAssessment: extension = v4.0,active; date = 2020-01-03; artifact[x] = -&gt;Evidence ExampleOutcomeEvidence</a></td></tr></table></blockquote></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-version"^^xsd:anyURI ] ;
fhir:value [ fhir:v "v4.0" ]
  ] [
fhir:url [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-publication-status"^^xsd:anyURI ] ;
fhir:value [ fhir:v "active" ]
  ] ) ; # 
  fhir:date [ fhir:v "2020-01-03"^^xsd:date] ; # 
  fhir:artifact [
a fhir:Reference ;
fhir:reference [ fhir:v "PlanDefinition/COVID19VentilatedPatientsDexamethasoneApplicationPlan" ]
  ] ; # 
  fhir:content ( [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "strength" ] ;
fhir:display [ fhir:v "Strength of recommendation" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-cs-recommendation-strength"^^xsd:anyURI ] ;
fhir:code [ fhir:v "strong-for" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "consensus" ] ;
fhir:display [ fhir:v "Consensus" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/recommendation-strength"^^xsd:anyURI ] ;
fhir:code [ fhir:v "strong" ] ;
fhir:display [ fhir:v "Strong" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "preference-and-values" ] ;
fhir:display [ fhir:v "Preference and values" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating"^^xsd:anyURI ] ;
fhir:code [ fhir:v "factor-not-considered" ] ;
fhir:display [ fhir:v "Factor not considered" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "resources" ] ;
fhir:display [ fhir:v "Resources" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating"^^xsd:anyURI ] ;
fhir:code [ fhir:v "no-important-issues" ] ;
fhir:display [ fhir:v "No important issues" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "acceptability" ] ;
fhir:display [ fhir:v "Acceptability" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating"^^xsd:anyURI ] ;
fhir:code [ fhir:v "factor-not-considered" ] ;
fhir:display [ fhir:v "Factor not considered" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "rating" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "feasibility" ] ;
fhir:display [ fhir:v "Feasibility" ]       ] )     ] ;
    ( fhir:classifier [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-evidence-to-decision-certainty-rating"^^xsd:anyURI ] ;
fhir:code [ fhir:v "factor-not-considered" ] ;
fhir:display [ fhir:v "Factor not considered" ]       ] )     ] )
  ] [
fhir:informationType [ fhir:v "container" ] ;
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "certainty-of-evidence-rating" ] ;
fhir:display [ fhir:v "Certainty of evidence rating" ]       ] )     ] ;
    ( fhir:relatedArtifact [
fhir:type [ fhir:v "justification" ] ;
      ( fhir:classifier [
        ( fhir:coding [
fhir:system [ fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"^^xsd:anyURI ] ;
fhir:code [ fhir:v "certainty-of-evidence-rating" ] ;
fhir:display [ fhir:v "Certainty of evidence rating" ]         ] )       ] ) ;
fhir:resourceReference [
fhir:reference [ fhir:v "ArtifactAssessment/DexamethasoneRatingOutcomeMortality" ]       ]     ] )
  ] ) . # 

<https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/study-citation> a fhir:Citation ;
  fhir:id [ fhir:v "SystemicCorticosteroidsForTheTreatmentOfCOVID19"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-citation"^^xsd:anyURI ;
fhir:link <https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-citation>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Citation_SystemicCorticosteroidsForTheTreatmentOfCOVID19\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Citation SystemicCorticosteroidsForTheTreatmentOfCOVID19</b></p><a name=\"SystemicCorticosteroidsForTheTreatmentOfCOVID19\"> </a><a name=\"hcSystemicCorticosteroidsForTheTreatmentOfCOVID19\"> </a><a name=\"SystemicCorticosteroidsForTheTreatmentOfCOVID19-en-US\"> </a><p><b>name</b>: SystemicCorticosteroidsForTheTreatmentOfCOVID19</p><p><b>status</b>: Active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: <code>https://pubmed.ncbi.nlm.nih.gov</code>/34396514, <code>https://doi.org</code>/10.1002/14651858.CD014963, <code>https://www.ncbi.nlm.nih.gov/pmc/</code>/PMC8406706</p><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td><div><p>Systemic corticosteroids for the treatment of COVID-19</p>\n</div></td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type publication-type}\">Publication Type</span></td><td><span title=\"Codes:{http://hl7.org/fhir/citation-artifact-classifier D016428}\">Journal Article</span></td></tr></table></blockquote></div>"
  ] ; # 
  fhir:name [ fhir:v "SystemicCorticosteroidsForTheTreatmentOfCOVID19"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:citedArtifact [
    ( fhir:identifier [
fhir:system [ fhir:v "https://pubmed.ncbi.nlm.nih.gov"^^xsd:anyURI ] ;
fhir:value [ fhir:v "34396514" ]     ] [
fhir:system [ fhir:v "https://doi.org"^^xsd:anyURI ] ;
fhir:value [ fhir:v "10.1002/14651858.CD014963" ]     ] [
fhir:system [ fhir:v "https://www.ncbi.nlm.nih.gov/pmc/"^^xsd:anyURI ] ;
fhir:value [ fhir:v "PMC8406706" ]     ] ) ;
    ( fhir:title [
fhir:text [ fhir:v "Systemic corticosteroids for the treatment of COVID-19" ]     ] ) ;
    ( fhir:classification [
fhir:type [
        ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "publication-type" ] ;
fhir:display [ fhir:v "Publication Type" ]         ] )       ] ;
      ( fhir:classifier [
        ( fhir:coding [
fhir:system [ fhir:v "http://hl7.org/fhir/citation-artifact-classifier"^^xsd:anyURI ] ;
fhir:code [ fhir:v "D016428" ] ;
fhir:display [ fhir:v "Journal Article" ]         ] )       ] )     ] )
  ] . #