Clinical Practice Guidelines (CPG) on EBMonFHIR
1.0.2 - ci-build
Clinical Practice Guidelines (CPG) on EBMonFHIR
1.0.2 - ci-build
Clinical Practice Guidelines (CPG) on EBMonFHIR, published by Universitätsmedizin Greifswald. This guide is not an authorized publication; it is the continuous build for version 1.0.2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/CEOsys/cpg-on-ebm-on-fhir/ and changes regularly. See the Directory of published versions
Generated Narrative: Bundle COVID19IntensiveCareTreatmentGuidelineBundle
Bundle COVID19IntensiveCareTreatmentGuidelineBundle of type collection
Entry 1 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/guideline
Resource Composition:
Generated Narrative: Composition COVID19IntensiveCareTreatmentGuideline
identifier: Resource identifier/113-001
version: 7.0
status: Final
type: Guidelines
category: Evidence- and consensus-based guideline
date: 2022-03-01
author: Organization Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) e.V.
title: Empfehlungen zur stationären Therapie von Patienten mit COVID-19 - Living Guideline
RelatesTos
Type ResourceReference Citation Citation COVID19_Intensive_Care_Treatment_Guideline
Entry 2 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/guideline-citation
Resource Citation:
Generated Narrative: Citation COVID19IntensiveCareTreatmentGuidelineCitation
name: COVID19_Intensive_Care_Treatment_Guideline
status: Active
citedArtifact
identifier:
https://www.awmf.org//113-001Versions
Value 7.0 currentState: Active
Titles
Text S3-Leitlinie Stationäre Therapie von COVID-19 Patienten
WebLocations
Url https://www.awmf.org/leitlinien/detail/ll/113-001.html Classifications
Type Classifier Publication Type Clinical practice guideline
Entry 3 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation
Resource PlanDefinition:
Generated Narrative: PlanDefinition COVID19DexamethasoneApplication
knowledgeCapability: computable
knowledgeRepresentationLevel: structured
Action Combination Method
- method: One or More
url: PlanDefinition Dexamethasone Application
version: 4.0
name: Dexamethasone_Application
title: Dexamethasone Application
type: Workflow Definition
status: Active
experimental: true
subject: Population_COVID19_Ventilated
date: 2021-12-12
publisher: CPGonEBMonFHIR
description:
Application of Dexamethasone for ventilated patients only
RelatedArtifacts
Type Classifier ResourceReference Justification Recommendation rating ArtifactAssessment: extension = v4.0,active; date = 2020-01-03; artifact[x] = ->PlanDefinition Dexamethasone Application in ventilated COVID-19 patients Citation Clinical practice guideline recommendation Citation DexamethasoneRecommendationCitation Citation Clinical practice guideline Citation COVID19_Intensive_Care_Treatment_Guideline action
title: Dexamethasone Application
description:
Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients
code: Guideline-based Care
definition: Dexamethasone Application in ventilated COVID-19 patients
action
title: No Dexamethasone Application
description:
No Dexamethasone Application for non-ventilated COVID-19 patients
code: Guideline-based Care
definition: No Dexamethasone Application for non-ventilated COVID-19 patients
Entry 4 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-plan-ventilated-patients
Resource PlanDefinition:
Generated Narrative: PlanDefinition COVID19VentilatedPatientsDexamethasoneApplicationPlan
knowledgeCapability: computable
knowledgeRepresentationLevel: structured
partOf: Dexamethasone Application
Action Combination Method
- method: Exactly
- threshold: 1
url: PlanDefinition Dexamethasone Application in ventilated COVID-19 patients
version: 4.0
name: Dexamethasone_Application
title: Dexamethasone Application in ventilated COVID-19 patients
type: ECA Rule
status: Active
experimental: true
subject: Population_COVID19_Ventilated
date: 2021-12-12
publisher: CPGonEBMonFHIR
description:
Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients
action
code: Administration of substance (procedure)
definition: DexamethasoneApplicationActionOral
action
code: Administration of substance (procedure)
definition: DexamethasoneApplicationActionIntravenous
Entry 5 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-plan-non-ventilated-patients
Resource PlanDefinition:
Generated Narrative: PlanDefinition COVID19NonVentilatedPatientsDexamethasoneApplicationPlan
knowledgeCapability: computable
knowledgeRepresentationLevel: structured
partOf: Dexamethasone Application
Action Combination Method
- method: Exactly
- threshold: 1
url: PlanDefinition No Dexamethasone Application for non-ventilated COVID-19 patients
version: 4.0
name: No_Dexamethasone_Application
title: No Dexamethasone Application for non-ventilated COVID-19 patients
type: ECA Rule
status: Active
experimental: true
subject: Population_COVID19_NonVentilated
date: 2021-12-12
publisher: CPGonEBMonFHIR
description:
No Dexamethasone Application for non-ventilated COVID19 patients
Actions
Code Definition[x] Administration of substance (procedure) NoDexamethasoneApplicationActivity
Entry 6 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-oral
Resource ActivityDefinition:
Generated Narrative: ActivityDefinition DexamethasoneApplicationActionOral
knowledgeCapability: computable
knowledgeRepresentationLevel: structured
url: ActivityDefinition DexamethasoneApplicationActionOral
version: 1.0
name: DexamethasoneApplicationActionOral
status: Active
experimental: true
subject: Patient
publisher: CPGonEBMonFHIR
description:
Application of Dexamethasone: 6 mg once per day for 10 days (oral route)
kind: MedicationRequest
code: Administration of substance (procedure)
product: Dexamethasone (substance)
dosage
timing: Count 10 times, Duration 10days , Once per 1 days
route: Oral route
DoseAndRates
Dose[x] Rate[x] 6 mg (Details: UCUM codemg = 'mg') 1 /d (Details: UCUM code/d = '/d')
Entry 7 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-intravenous
Resource ActivityDefinition:
Generated Narrative: ActivityDefinition DexamethasoneApplicationActionIntravenous
knowledgeCapability: computable
knowledgeRepresentationLevel: structured
url: ActivityDefinition DexamethasoneApplicationActionIntravenous
version: 1.0
name: DexamethasoneApplicationActionIntravenous
status: Active
experimental: true
subject: Patient
publisher: CPGonEBMonFHIR
description:
Application of Dexamethasone: 6 mg once per day for 10 days (intravenous route)
kind: MedicationRequest
code: Administration of substance (procedure)
product: Dexamethasone (substance)
dosage
timing: Count 10 times, Duration 10days , Once per 1 days
route: Intravenous route
DoseAndRates
Dose[x] Rate[x] 6 mg (Details: UCUM codemg = 'mg') 1 /d (Details: UCUM code/d = '/d')
Entry 8 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-no-application
Resource ActivityDefinition:
Generated Narrative: ActivityDefinition NoDexamethasoneApplication
knowledgeCapability: computable
knowledgeRepresentationLevel: structured
url: ActivityDefinition NoDexamethasoneApplicationActivity
version: 1.0
name: NoDexamethasoneApplicationActivity
status: Active
experimental: true
subject: Patient
publisher: CPGonEBMonFHIR
description:
No Application of Dexamethasone
kind: MedicationRequest
code: Administration of substance (procedure)
doNotPerform: true
product: Dexamethasone (substance)
Entry 9 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-citation
Resource Citation:
Generated Narrative: Citation DexamethasoneRecommendationCitation
name: DexamethasoneRecommendationCitation
status: Active
citedArtifact
identifier:
https://api.magicapp.org/api/v1/recommendations/98398Versions
Value v4.0 currentState: Active
Titles
Text Steroide
Classifications
Type Classifier Publication Type Clinical practice guideline recommendation
Entry 10 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-ventilated
Resource EvidenceVariable:
Generated Narrative: EvidenceVariable PopulationCOVID19Ventilated
url: EvidenceVariable Population_COVID19_Ventilated
identifier:
https://www.ceosys.de/Ventilatedname: Population_COVID19_Ventilated
status: Active
description:
Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, Ventilated
characteristic
linkId: covid19
DefinitionByTypeAndValues
Type Value[x] Clinical finding (finding) Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) characteristic
exclude: false
definitionByCombination
code: Any of
characteristic
linkId: oxy-administration-nasal-cannula
exclude: false
DefinitionByTypeAndValues
Type Value[x] Procedure (procedure) Oxygen administration by nasal cannula (procedure) TimeFromEvents
Event[x] Quantity covid19 0 d (Details: UCUM coded = 'd') characteristic
linkId: noninvasive-ventilation
exclude: false
DefinitionByTypeAndValues
Type Value[x] Procedure (procedure) Non-invasive ventilation (regime/therapy) TimeFromEvents
Event[x] Quantity covid19 0 d (Details: UCUM coded = 'd') characteristic
linkId: artificial-respiration
exclude: false
DefinitionByTypeAndValues
Type Value[x] Procedure (procedure) Artificial ventilation (regime/therapy) TimeFromEvents
Event[x] Quantity covid19 0 d (Details: UCUM coded = 'd')
Entry 11 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-non-ventilated
Resource EvidenceVariable:
Generated Narrative: EvidenceVariable PopulationCOVID19NonVentilated
url: EvidenceVariable Population_COVID19_NonVentilated
identifier:
https://www.ceosys.de/NonVentilatedname: Population_COVID19_NonVentilated
status: Active
description:
Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, not ventilated
characteristic
linkId: covid19
exclude: false
DefinitionByTypeAndValues
Type Value[x] Clinical finding (finding) Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) characteristic
exclude: true
definitionByCombination
code: Any of
characteristic
linkId: oxy-administration-nasal-cannula
exclude: false
DefinitionByTypeAndValues
Type Value[x] Procedure (procedure) Oxygen administration by nasal cannula (procedure) TimeFromEvents
Event[x] Quantity covid19 0 d (Details: UCUM coded = 'd') characteristic
linkId: noninvasive-ventilation
exclude: false
DefinitionByTypeAndValues
Type Value[x] Procedure (procedure) Non-invasive ventilation (regime/therapy) TimeFromEvents
Event[x] Quantity covid19 0 d (Details: UCUM coded = 'd') characteristic
linkId: artificial-respiration
exclude: false
DefinitionByTypeAndValues
Type Value[x] Procedure (procedure) Artificial ventilation (regime/therapy) TimeFromEvents
Event[x] Quantity covid19 0 d (Details: UCUM coded = 'd')
Entry 12 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/rating-outcome-mortality
Resource ArtifactAssessment:
Generated Narrative: ArtifactAssessment DexamethasoneRatingOutcomeMortality
ArtifactAssessment Version: v4.0
ArtifactAssessment Publication Status: active
date: 2020-01-03
artifact: Evidence ExampleOutcomeEvidence
content
informationType: Rating
type: Overall certainty
classifier: Moderate quality
content
informationType: Rating
type: Clinical Importance
classifier: Critical
content
informationType: Rating
type: Risk of bias
classifier: serious concern
content
informationType: Rating
type: Inconsistency
classifier: no serious concern
content
informationType: Rating
type: Indirectness
classifier: no serious concern
content
informationType: Rating
type: Imprecision
classifier: no serious concern
content
informationType: Rating
type: Publication bias
classifier: no serious concern
Entry 13 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/outcome-mortality
Resource Evidence:
Generated Narrative: Evidence DexamethasoneOutcomeMortality
name: ExampleOutcomeEvidence
status: Active
RelatedArtifacts
Type ResourceReference Citation Citation SystemicCorticosteroidsForTheTreatmentOfCOVID19 variableDefinition
variableRole: population
observed: Group StudyCohortCriteriaSystemicCorticosteroidsCOVID19
intended: EvidenceVariable StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19
variableDefinition
variableRole: measured variable
observed: EvidenceVariable AllCauseMortality
synthesisType: not applicable
statistic
description:
Relative effect of intervention vs. comparator
statisticType: Relative Risk
quantity: 0.89
SampleSizes
NumberOfStudies NumberOfParticipants 9 7930 AttributeEstimates
Type Level Range Confidence interval 0.95 0.8-1 statistic
description:
Baseline risk/result in the comparison group
statisticType: Incidence
quantity: 245 1/1000 (Details: UCUM code1/1000 = '1/1000')
Entry 14 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/study-eligibility-criteria
Resource EvidenceVariable:
Generated Narrative: EvidenceVariable StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19
name: StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19
status: Active
characteristic
DefinitionByTypeAndValues
Type Value[x] Clinical finding (finding) Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)
Entry 15 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/outcome-all-cause-mortality
Resource EvidenceVariable:
Generated Narrative: EvidenceVariable OutcomeAllCauseMortality
name: AllCauseMortality
status: Active
Characteristics
Exclude DefinitionCodeableConcept false Mortality rate (observable entity) handling: dichotomous variable
Entry 16 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-justification
Resource ArtifactAssessment:
Generated Narrative: ArtifactAssessment DexamethasoneRecommendationJustification
ArtifactAssessment Version: v4.0
ArtifactAssessment Publication Status: active
date: 2020-01-03
artifact: PlanDefinition Dexamethasone Application in ventilated COVID-19 patients
content
informationType: Rating
type: Strength of recommendation
classifier: Strong for an intervention
content
informationType: Rating
type: Consensus
classifier: Strong
content
informationType: Rating
type: Preference and values
classifier: Factor not considered
content
informationType: Rating
type: Resources
classifier: No important issues
content
informationType: Rating
type: Acceptability
classifier: Factor not considered
content
informationType: Rating
type: Feasibility
classifier: Factor not considered
content
informationType: Container
type: Certainty of evidence rating
RelatedArtifacts
Type Classifier ResourceReference Justification Certainty of evidence rating ArtifactAssessment: extension = v4.0,active; date = 2020-01-03; artifact[x] = ->Evidence ExampleOutcomeEvidence
Entry 17 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/study-citation
Resource Citation:
Generated Narrative: Citation SystemicCorticosteroidsForTheTreatmentOfCOVID19
name: SystemicCorticosteroidsForTheTreatmentOfCOVID19
status: Active
citedArtifact
identifier:
https://pubmed.ncbi.nlm.nih.gov/34396514,https://doi.org/10.1002/14651858.CD014963,https://www.ncbi.nlm.nih.gov/pmc//PMC8406706Titles
Text Systemic corticosteroids for the treatment of COVID-19
Classifications
Type Classifier Publication Type Journal Article
IG © 2021+ Universitätsmedizin Greifswald. Package de.netzwerk-universitaetsmedizin.ebm-cpg#1.0.2 based on FHIR 5.0.0. Generated 2024-10-21
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