Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

Example Evidence: ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study

Active as of 2022-09-19

Generated Narrative: Evidence 104156

version: 9; Last updated: 2023-12-06 00:51:34+0000

Profiles: ComparativeEvidence, SingleStudyEvidence

url: Evidence ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study

identifier: FEvIR Object Identifier/104156, Uniform Resource Identifier (URI)/urn:oid:2.16.840.1.113883.4.642.40.44.22.14

version: 2.0.0-ballot

name: ComparativeEvidence_Bypass_surgery_effects_on_Treatment_with_opioids_in_JAMA_2018_Norwegian_cohort_study

title: ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study

status: Active

date: 2022-09-19 21:16:36+0000

publisher: HL7 International / Clinical Decision Support

contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss

author: Brian S. Alper:

UseContexts

-CodeValue[x]
*Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence CommunicationComparativeEvidence
*Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence CommunicationSingleStudyEvidence

copyright:

https://creativecommons.org/licenses/by-nc-sa/4.0/

relatedArtifact

type: Derived From

Documents

-Url
*https://jamanetwork.com/journals/jama/fullarticle/2669729

relatedArtifact

type: Cite As

citation:

ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 104156. Revised 2022-09-19. Available at: https://fevir.net/resources/Evidence/104156. Computable resource at: https://fevir.net/resources/Evidence/104156.

description:

greater risk of treatment with opioids: AR, 19.4% vs 15.8%, RD, 3.6% [95% CI, 2.3%-4.9%], RR, 1.3 [95% CI, 1.2-1.4]

assertion:

Compared with specialized medical treatment, bariatric surgery may slightly increase the use of opioids.

variableDefinition

org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: population

description:

Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n = 2109) with severe obesity assessed (221 patients excluded and 1888 patients included).

note: population

observed: StudyGroup: Severely Obese Adults 2018 Norwegian Cohort

variableDefinition

org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: exposure

org/fhir/uv/ebm/StructureDefinition/variable-definition-comparator-category: no bariatric surgery

description:

bariatric surgery vs. specialized medical treatment without bariatric surgery

note: exposure

intended: GroupAssignment: Bariatric Surgery vs. no bariatric surgery

variableDefinition

org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: outcome

description:

Treatment with opioids

note: outcome

observed: OutcomeVariable: Treatment with opioids

synthesisType: not applicable

studyDesign: Observational research, Parallel cohort design, Longitudinal data collection

statistic

description:

Relative risk 1.3; 95% CI 1.2 to 1.4

note: Result observed without bariatric surgery was 15.8%, result observed with bariatric surgery was 19.4%

statisticType: Relative Risk

quantity: 1.3

SampleSizes

-NumberOfStudiesNumberOfParticipantsKnownDataCount
*118881888

AttributeEstimates

-DescriptionTypeLevelRange
*

95% CI 1.2 to 1.4

Confidence interval0.951.2-1.4

Certainties

-DescriptionTypeRating
*

rated down 2 levels due to observational study

Overall certaintyLow quality