Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

Example Evidence: ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study

Active as of 2022-09-19

Generated Narrative: Evidence 104121

version: 12; Last updated: 2023-12-06 00:53:26+0000

Profiles: ComparativeEvidence, SingleStudyEvidence

url: Evidence ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study

identifier: FEvIR Object Identifier/104121, Uniform Resource Identifier (URI)/urn:oid:2.16.840.1.113883.4.642.40.44.22.12

version: 2.0.0-ballot

name: ComparativeEvidence_Bypass_surgery_effects_on_Remission_of_diabetes_in_JAMA_2018_Norwegian_cohort_study

title: ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study

status: Active

date: 2022-09-19 21:16:23+0000

publisher: HL7 International / Clinical Decision Support

contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss

author: Brian S. Alper:

UseContexts

-CodeValue[x]
*Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence CommunicationComparativeEvidence
*Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence CommunicationSingleStudyEvidence

copyright:

https://creativecommons.org/licenses/by-nc-sa/4.0/

relatedArtifact

type: Derived From

Documents

-Url
*https://jamanetwork.com/journals/jama/fullarticle/2669729

relatedArtifact

type: Cite As

citation:

ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 104121. Revised 2022-09-19. Available at: https://fevir.net/resources/Evidence/104121. Computable resource at: https://fevir.net/resources/Evidence/104121.

description:

greater likelihood of diabetes remission: AR, 57.5% vs 14.8%; RD, 42.7% [95% CI, 35.8%-49.7%], RR, 3.9 [95% CI, 2.8-5.4]

assertion:

Compared with specialized medical treatment, bariatric surgery appears to induce remission of diabetes.

variableDefinition

org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: population

description:

Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n = 2109) with severe obesity assessed (221 patients excluded and 1888 patients included).

note: population

observed: StudyGroup: Severely Obese Adults 2018 Norwegian Cohort

variableDefinition

org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: exposure

org/fhir/uv/ebm/StructureDefinition/variable-definition-comparator-category: no bariatric surgery

description:

bariatric surgery vs. specialized medical treatment without bariatric surgery

note: exposure

intended: GroupAssignment: Bariatric Surgery vs. no bariatric surgery

variableDefinition

org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code: outcome

description:

Remission of diabetes

note: outcome

observed: OutcomeVariable: Remission of diabetes

synthesisType: not applicable

studyDesign: Observational research, Parallel cohort design, Longitudinal data collection

statistic

description:

Relative risk 3.9; 95% CI 2.8 to 5.4

note: Result observed without bariatric surgery was 14.8%, result observed with bariatric surgery was 57.5%

statisticType: Relative Risk

quantity: 3.9

SampleSizes

-NumberOfStudiesNumberOfParticipantsKnownDataCount
*118881888

AttributeEstimates

-DescriptionTypeLevelRange
*

95% CI 2.8 to 5.4

Confidence interval0.952.8-5.4

Certainties

-DescriptionTypeRating
*

rated down 2 levels due to observational study, rated up 1 level due to large effect size

Overall certaintyModerate quality