IDEA4RC FHIR Implementation Guide
0.1.0 - CI Build 150

IDEA4RC FHIR Implementation Guide, published by IDEA4RC Project. This guide is not an authorized publication; it is the continuous build for version 0.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-eu/idea4rc/ and changes regularly. See the Directory of published versions

Logical Model: DiseaseExtentI4RC - Detailed Descriptions

Draft as of 2025-07-25

Definitions for the DiseaseExtent logical model.

Guidance on how to interpret the contents of this table can be foundhere

0. DiseaseExtent
Definition

Disease Extent Maturity Level: 0 Draft

ShortDisease Extent
Control0..*
Is Modifierfalse
Logical ModelInstances of this logical model are not marked to be the target of a Reference
2. DiseaseExtent.episodeEvent
Definition

EpisodeEvent element containing the data regarding the patient's cancer

ShortEpisode Event Reference (M)
Control1..*
Typehttp://hl7.eu/fhir/ig/idea4rc/StructureDefinition/EpisodeEvent
Obligations
    ObligationsActor
    SHALL:handleHead and Neck
    SHALL:handleSarcoma
    4. DiseaseExtent.localised
    Definition

    Describes if there disease is local Localised and Number of tumor modules are variables that work together

    ShortLocalised (M)
    Comments

    Confined disease - 32942

    Control1..*
    Typeboolean
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Obligations
      ObligationsActor
      SHALL:handleHead and Neck
      SHALL:handleSarcoma
      6. DiseaseExtent.numberOfTumorNodules
      Definition

      Indicates the number of tumor nodules in the case the disease is localised Localised and Number of tumor modules are variables that work together

      ShortNumber of tumor nodules (R)
      Comments

      Number of tumor nodules - 4228659

      Control0..*
      Typeinteger
      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
      Obligations
        ObligationsActor
        SHALL:handleHead and Neck
        SHALL:handleSarcoma
        8. DiseaseExtent.locoRegional
        Definition

        Indicates if the disease is in a loco-regional extent

        ShortLoco-regional (M)
        Comments

        Invasive Disease - 32943

        Control1..*
        Typeboolean
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Obligations
          ObligationsActor
          SHALL:handleHead and Neck
          SHALL:handleSarcoma
          10. DiseaseExtent.isTransitMetastasisWithClinicalConfirmation
          Definition

          Indicates spread of cancer cells through lymphatic vessels, where they lodge and grow in tissues located between the primary tumor and the nearest regional lymph nodes.

          ShortIs Transit metastasis with clinical confirmation (M)
          Comments

          Transit Metastasis with Clinical Confirmation - 36769249

          Control1..*
          Typeboolean
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Obligations
            ObligationsActor
            SHALL:handleHead and Neck
            SHALL:handleSarcoma
            12. DiseaseExtent.isMultifocalTumor
            Definition

            Presence of multiple distinct tumor foci (or nodules) within the same organ or tissue, originating from the same primary tumor type. These foci may arise through independent tumorigenesis (multiple primary lesions) or local spread of the same cancer.

            ShortIs Multifocal tumor (M)
            Comments

            Multifocal Tumor - 36769933

            Control1..*
            Typeboolean
            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
            Obligations
              ObligationsActor
              SHALL:handleHead and Neck
              SHALL:handleSarcoma
              14. DiseaseExtent.regionalNodalMetastases
              Definition

              Describes if regional nodal mestastases happened

              ShortRegional nodal metastases (M)
              Comments

              Regional spread to lymph node - 36769269

              Control1..*
              Typeboolean
              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
              Obligations
                ObligationsActor
                SHALL:handleHead and Neck
                SHALL:handleSarcoma
                16. DiseaseExtent.sites
                Definition

                Describes if site of metastasic disease is soft tissue

                Shortsites (R)
                Control0..*
                TypeBackboneElement
                Obligations
                  ObligationsActor
                  SHALL:handleHead and Neck
                  SHALL:handleSarcoma
                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                  18. DiseaseExtent.sites.id
                  Definition

                  Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                  ShortUnique id for inter-element referencing
                  Control0..1
                  Typestring
                  Is Modifierfalse
                  XML FormatIn the XML format, this property is represented as an attribute.
                  Summaryfalse
                  20. DiseaseExtent.sites.extension
                  Definition

                  May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                  ShortAdditional content defined by implementations
                  Comments

                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                  Control0..*
                  TypeExtension
                  Is Modifierfalse
                  Summaryfalse
                  Alternate Namesextensions, user content
                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                  SlicingThis element introduces a set of slices on DiseaseExtent.sites.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                  • value @ url
                  • 22. DiseaseExtent.sites.modifierExtension
                    Definition

                    May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                    Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                    ShortExtensions that cannot be ignored even if unrecognized
                    Comments

                    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                    Control0..*
                    TypeExtension
                    Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                    Summarytrue
                    Requirements

                    Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                    Alternate Namesextensions, user content, modifiers
                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                    24. DiseaseExtent.sites.softTissue
                    Definition

                    Describes if site of metastasic disease is soft tissue

                    ShortSoft tissue (R)
                    Comments

                    Metastasis to soft tissues - 35225724

                    Control0..*
                    Typeboolean
                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                    Obligations
                      ObligationsActor
                      SHALL:handleHead and Neck
                      SHALL:handleSarcoma
                      26. DiseaseExtent.sites.distantLymphNode
                      Definition

                      Describes if site of metastasic disease is dystan lymph node

                      Shortdistant lymph node (R)
                      Comments

                      Distant spread to lymph node - 36769243

                      Control0..*
                      Typeboolean
                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                      Obligations
                        ObligationsActor
                        SHALL:handleHead and Neck
                        SHALL:handleSarcoma
                        28. DiseaseExtent.sites.lung
                        Definition

                        Describes if site of metastasic disease is lung

                        Shortlung (R)
                        Comments

                        Metastasis to lung - 36770283

                        Control0..*
                        Typeboolean
                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                        Obligations
                          ObligationsActor
                          SHALL:handleHead and Neck
                          SHALL:handleSarcoma
                          30. DiseaseExtent.sites.metastasisatbone
                          Definition

                          Describes if site of metastasic disease is bone

                          ShortmetastasisAtBone (R)
                          Comments

                          Metastasis to bone - 36769301

                          Control0..*
                          Typeboolean
                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                          Obligations
                            ObligationsActor
                            SHALL:handleHead and Neck
                            SHALL:handleSarcoma
                            32. DiseaseExtent.sites.liver
                            Definition

                            Describes if site of metastasic disease is liver

                            Shortliver (R)
                            Comments

                            Metastasis to liver - 36770544

                            Control0..*
                            Typeboolean
                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                            Obligations
                              ObligationsActor
                              SHALL:handleHead and Neck
                              SHALL:handleSarcoma
                              34. DiseaseExtent.sites.pleura
                              Definition

                              Describes if site of metastasic disease is pleura

                              Shortpleura (R)
                              Comments

                              Metastasis to pleura - 35226258

                              Control0..*
                              Typeboolean
                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                              Obligations
                                ObligationsActor
                                SHALL:handleHead and Neck
                                SHALL:handleSarcoma
                                36. DiseaseExtent.sites.peritoneum
                                Definition

                                Describes if site of metastasic disease is peritoneum

                                Shortperitoneum (R)
                                Comments

                                Metastasis to peritoneum - 35226253

                                Control0..*
                                Typeboolean
                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                Obligations
                                  ObligationsActor
                                  SHALL:handleHead and Neck
                                  SHALL:handleSarcoma
                                  38. DiseaseExtent.sites.brain
                                  Definition

                                  Describes if site of metastasic disease is brain

                                  Shortbrain (R)
                                  Comments

                                  Metastasis to brain - 36768862

                                  Control0..*
                                  Typeboolean
                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                  Obligations
                                    ObligationsActor
                                    SHALL:handleHead and Neck
                                    SHALL:handleSarcoma
                                    40. DiseaseExtent.sites.otherViscera
                                    Definition

                                    Describes if site of metastasic disease is other viscera Use the generic metastasis code or a metastasis subsumed in it, 36769180

                                    Shortother viscera (R)
                                    Comments

                                    Metastasis - 36769180

                                    Control0..*
                                    Typeboolean
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Obligations
                                      ObligationsActor
                                      SHALL:handleHead and Neck
                                      SHALL:handleSarcoma

                                      Guidance on how to interpret the contents of this table can be foundhere

                                      0. DiseaseExtent
                                      Definition

                                      Disease Extent Maturity Level: 0 Draft

                                      ShortDisease Extent
                                      Logical ModelInstances of this logical model are not marked to be the target of a Reference
                                      2. DiseaseExtent.episodeEvent
                                      Definition

                                      EpisodeEvent element containing the data regarding the patient's cancer

                                      ShortEpisode Event Reference (M)
                                      Control1..*
                                      Typehttp://hl7.eu/fhir/ig/idea4rc/StructureDefinition/EpisodeEvent
                                      Obligations
                                        ObligationsActor
                                        SHALL:handleHead and Neck
                                        SHALL:handleSarcoma
                                        4. DiseaseExtent.localised
                                        Definition

                                        Describes if there disease is local Localised and Number of tumor modules are variables that work together

                                        ShortLocalised (M)
                                        Comments

                                        Confined disease - 32942

                                        Control1..*
                                        Typeboolean
                                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                        Obligations
                                          ObligationsActor
                                          SHALL:handleHead and Neck
                                          SHALL:handleSarcoma
                                          6. DiseaseExtent.numberOfTumorNodules
                                          Definition

                                          Indicates the number of tumor nodules in the case the disease is localised Localised and Number of tumor modules are variables that work together

                                          ShortNumber of tumor nodules (R)
                                          Comments

                                          Number of tumor nodules - 4228659

                                          Control0..*
                                          Typeinteger
                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                          Obligations
                                            ObligationsActor
                                            SHALL:handleHead and Neck
                                            SHALL:handleSarcoma
                                            8. DiseaseExtent.locoRegional
                                            Definition

                                            Indicates if the disease is in a loco-regional extent

                                            ShortLoco-regional (M)
                                            Comments

                                            Invasive Disease - 32943

                                            Control1..*
                                            Typeboolean
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Obligations
                                              ObligationsActor
                                              SHALL:handleHead and Neck
                                              SHALL:handleSarcoma
                                              10. DiseaseExtent.isTransitMetastasisWithClinicalConfirmation
                                              Definition

                                              Indicates spread of cancer cells through lymphatic vessels, where they lodge and grow in tissues located between the primary tumor and the nearest regional lymph nodes.

                                              ShortIs Transit metastasis with clinical confirmation (M)
                                              Comments

                                              Transit Metastasis with Clinical Confirmation - 36769249

                                              Control1..*
                                              Typeboolean
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              Obligations
                                                ObligationsActor
                                                SHALL:handleHead and Neck
                                                SHALL:handleSarcoma
                                                12. DiseaseExtent.isMultifocalTumor
                                                Definition

                                                Presence of multiple distinct tumor foci (or nodules) within the same organ or tissue, originating from the same primary tumor type. These foci may arise through independent tumorigenesis (multiple primary lesions) or local spread of the same cancer.

                                                ShortIs Multifocal tumor (M)
                                                Comments

                                                Multifocal Tumor - 36769933

                                                Control1..*
                                                Typeboolean
                                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                Obligations
                                                  ObligationsActor
                                                  SHALL:handleHead and Neck
                                                  SHALL:handleSarcoma
                                                  14. DiseaseExtent.regionalNodalMetastases
                                                  Definition

                                                  Describes if regional nodal mestastases happened

                                                  ShortRegional nodal metastases (M)
                                                  Comments

                                                  Regional spread to lymph node - 36769269

                                                  Control1..*
                                                  Typeboolean
                                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                  Obligations
                                                    ObligationsActor
                                                    SHALL:handleHead and Neck
                                                    SHALL:handleSarcoma
                                                    16. DiseaseExtent.sites
                                                    Definition

                                                    Describes if site of metastasic disease is soft tissue

                                                    Shortsites (R)
                                                    Control0..*
                                                    TypeBackboneElement
                                                    Obligations
                                                      ObligationsActor
                                                      SHALL:handleHead and Neck
                                                      SHALL:handleSarcoma
                                                      18. DiseaseExtent.sites.softTissue
                                                      Definition

                                                      Describes if site of metastasic disease is soft tissue

                                                      ShortSoft tissue (R)
                                                      Comments

                                                      Metastasis to soft tissues - 35225724

                                                      Control0..*
                                                      Typeboolean
                                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                      Obligations
                                                        ObligationsActor
                                                        SHALL:handleHead and Neck
                                                        SHALL:handleSarcoma
                                                        20. DiseaseExtent.sites.distantLymphNode
                                                        Definition

                                                        Describes if site of metastasic disease is dystan lymph node

                                                        Shortdistant lymph node (R)
                                                        Comments

                                                        Distant spread to lymph node - 36769243

                                                        Control0..*
                                                        Typeboolean
                                                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                        Obligations
                                                          ObligationsActor
                                                          SHALL:handleHead and Neck
                                                          SHALL:handleSarcoma
                                                          22. DiseaseExtent.sites.lung
                                                          Definition

                                                          Describes if site of metastasic disease is lung

                                                          Shortlung (R)
                                                          Comments

                                                          Metastasis to lung - 36770283

                                                          Control0..*
                                                          Typeboolean
                                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                          Obligations
                                                            ObligationsActor
                                                            SHALL:handleHead and Neck
                                                            SHALL:handleSarcoma
                                                            24. DiseaseExtent.sites.metastasisatbone
                                                            Definition

                                                            Describes if site of metastasic disease is bone

                                                            ShortmetastasisAtBone (R)
                                                            Comments

                                                            Metastasis to bone - 36769301

                                                            Control0..*
                                                            Typeboolean
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Obligations
                                                              ObligationsActor
                                                              SHALL:handleHead and Neck
                                                              SHALL:handleSarcoma
                                                              26. DiseaseExtent.sites.liver
                                                              Definition

                                                              Describes if site of metastasic disease is liver

                                                              Shortliver (R)
                                                              Comments

                                                              Metastasis to liver - 36770544

                                                              Control0..*
                                                              Typeboolean
                                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                              Obligations
                                                                ObligationsActor
                                                                SHALL:handleHead and Neck
                                                                SHALL:handleSarcoma
                                                                28. DiseaseExtent.sites.pleura
                                                                Definition

                                                                Describes if site of metastasic disease is pleura

                                                                Shortpleura (R)
                                                                Comments

                                                                Metastasis to pleura - 35226258

                                                                Control0..*
                                                                Typeboolean
                                                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                Obligations
                                                                  ObligationsActor
                                                                  SHALL:handleHead and Neck
                                                                  SHALL:handleSarcoma
                                                                  30. DiseaseExtent.sites.peritoneum
                                                                  Definition

                                                                  Describes if site of metastasic disease is peritoneum

                                                                  Shortperitoneum (R)
                                                                  Comments

                                                                  Metastasis to peritoneum - 35226253

                                                                  Control0..*
                                                                  Typeboolean
                                                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                  Obligations
                                                                    ObligationsActor
                                                                    SHALL:handleHead and Neck
                                                                    SHALL:handleSarcoma
                                                                    32. DiseaseExtent.sites.brain
                                                                    Definition

                                                                    Describes if site of metastasic disease is brain

                                                                    Shortbrain (R)
                                                                    Comments

                                                                    Metastasis to brain - 36768862

                                                                    Control0..*
                                                                    Typeboolean
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Obligations
                                                                      ObligationsActor
                                                                      SHALL:handleHead and Neck
                                                                      SHALL:handleSarcoma
                                                                      34. DiseaseExtent.sites.otherViscera
                                                                      Definition

                                                                      Describes if site of metastasic disease is other viscera Use the generic metastasis code or a metastasis subsumed in it, 36769180

                                                                      Shortother viscera (R)
                                                                      Comments

                                                                      Metastasis - 36769180

                                                                      Control0..*
                                                                      Typeboolean
                                                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                      Obligations
                                                                        ObligationsActor
                                                                        SHALL:handleHead and Neck
                                                                        SHALL:handleSarcoma

                                                                        Guidance on how to interpret the contents of this table can be foundhere

                                                                        0. DiseaseExtent
                                                                        Definition

                                                                        Disease Extent Maturity Level: 0 Draft

                                                                        ShortDisease Extent
                                                                        Control0..*
                                                                        Is Modifierfalse
                                                                        Logical ModelInstances of this logical model are not marked to be the target of a Reference
                                                                        2. DiseaseExtent.episodeEvent
                                                                        Definition

                                                                        EpisodeEvent element containing the data regarding the patient's cancer

                                                                        ShortEpisode Event Reference (M)
                                                                        Control1..*
                                                                        Typehttp://hl7.eu/fhir/ig/idea4rc/StructureDefinition/EpisodeEvent
                                                                        Obligations
                                                                          ObligationsActor
                                                                          SHALL:handleHead and Neck
                                                                          SHALL:handleSarcoma
                                                                          4. DiseaseExtent.localised
                                                                          Definition

                                                                          Describes if there disease is local Localised and Number of tumor modules are variables that work together

                                                                          ShortLocalised (M)
                                                                          Comments

                                                                          Confined disease - 32942

                                                                          Control1..*
                                                                          Typeboolean
                                                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                          Obligations
                                                                            ObligationsActor
                                                                            SHALL:handleHead and Neck
                                                                            SHALL:handleSarcoma
                                                                            6. DiseaseExtent.numberOfTumorNodules
                                                                            Definition

                                                                            Indicates the number of tumor nodules in the case the disease is localised Localised and Number of tumor modules are variables that work together

                                                                            ShortNumber of tumor nodules (R)
                                                                            Comments

                                                                            Number of tumor nodules - 4228659

                                                                            Control0..*
                                                                            Typeinteger
                                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                            Obligations
                                                                              ObligationsActor
                                                                              SHALL:handleHead and Neck
                                                                              SHALL:handleSarcoma
                                                                              8. DiseaseExtent.locoRegional
                                                                              Definition

                                                                              Indicates if the disease is in a loco-regional extent

                                                                              ShortLoco-regional (M)
                                                                              Comments

                                                                              Invasive Disease - 32943

                                                                              Control1..*
                                                                              Typeboolean
                                                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                              Obligations
                                                                                ObligationsActor
                                                                                SHALL:handleHead and Neck
                                                                                SHALL:handleSarcoma
                                                                                10. DiseaseExtent.isTransitMetastasisWithClinicalConfirmation
                                                                                Definition

                                                                                Indicates spread of cancer cells through lymphatic vessels, where they lodge and grow in tissues located between the primary tumor and the nearest regional lymph nodes.

                                                                                ShortIs Transit metastasis with clinical confirmation (M)
                                                                                Comments

                                                                                Transit Metastasis with Clinical Confirmation - 36769249

                                                                                Control1..*
                                                                                Typeboolean
                                                                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                Obligations
                                                                                  ObligationsActor
                                                                                  SHALL:handleHead and Neck
                                                                                  SHALL:handleSarcoma
                                                                                  12. DiseaseExtent.isMultifocalTumor
                                                                                  Definition

                                                                                  Presence of multiple distinct tumor foci (or nodules) within the same organ or tissue, originating from the same primary tumor type. These foci may arise through independent tumorigenesis (multiple primary lesions) or local spread of the same cancer.

                                                                                  ShortIs Multifocal tumor (M)
                                                                                  Comments

                                                                                  Multifocal Tumor - 36769933

                                                                                  Control1..*
                                                                                  Typeboolean
                                                                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                  Obligations
                                                                                    ObligationsActor
                                                                                    SHALL:handleHead and Neck
                                                                                    SHALL:handleSarcoma
                                                                                    14. DiseaseExtent.regionalNodalMetastases
                                                                                    Definition

                                                                                    Describes if regional nodal mestastases happened

                                                                                    ShortRegional nodal metastases (M)
                                                                                    Comments

                                                                                    Regional spread to lymph node - 36769269

                                                                                    Control1..*
                                                                                    Typeboolean
                                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                    Obligations
                                                                                      ObligationsActor
                                                                                      SHALL:handleHead and Neck
                                                                                      SHALL:handleSarcoma
                                                                                      16. DiseaseExtent.sites
                                                                                      Definition

                                                                                      Describes if site of metastasic disease is soft tissue

                                                                                      Shortsites (R)
                                                                                      Control0..*
                                                                                      TypeBackboneElement
                                                                                      Obligations
                                                                                        ObligationsActor
                                                                                        SHALL:handleHead and Neck
                                                                                        SHALL:handleSarcoma
                                                                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                                        18. DiseaseExtent.sites.id
                                                                                        Definition

                                                                                        Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                                                        ShortUnique id for inter-element referencing
                                                                                        Control0..1
                                                                                        Typestring
                                                                                        Is Modifierfalse
                                                                                        XML FormatIn the XML format, this property is represented as an attribute.
                                                                                        Summaryfalse
                                                                                        20. DiseaseExtent.sites.extension
                                                                                        Definition

                                                                                        May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                                                        ShortAdditional content defined by implementations
                                                                                        Comments

                                                                                        There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                                        Control0..*
                                                                                        TypeExtension
                                                                                        Is Modifierfalse
                                                                                        Summaryfalse
                                                                                        Alternate Namesextensions, user content
                                                                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                                        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                                        SlicingThis element introduces a set of slices on DiseaseExtent.sites.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                                                        • value @ url
                                                                                        • 22. DiseaseExtent.sites.modifierExtension
                                                                                          Definition

                                                                                          May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                                                          Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                                                          ShortExtensions that cannot be ignored even if unrecognized
                                                                                          Comments

                                                                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                                          Control0..*
                                                                                          TypeExtension
                                                                                          Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                                                          Summarytrue
                                                                                          Requirements

                                                                                          Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                                                          Alternate Namesextensions, user content, modifiers
                                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                                          24. DiseaseExtent.sites.softTissue
                                                                                          Definition

                                                                                          Describes if site of metastasic disease is soft tissue

                                                                                          ShortSoft tissue (R)
                                                                                          Comments

                                                                                          Metastasis to soft tissues - 35225724

                                                                                          Control0..*
                                                                                          Typeboolean
                                                                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                          Obligations
                                                                                            ObligationsActor
                                                                                            SHALL:handleHead and Neck
                                                                                            SHALL:handleSarcoma
                                                                                            26. DiseaseExtent.sites.distantLymphNode
                                                                                            Definition

                                                                                            Describes if site of metastasic disease is dystan lymph node

                                                                                            Shortdistant lymph node (R)
                                                                                            Comments

                                                                                            Distant spread to lymph node - 36769243

                                                                                            Control0..*
                                                                                            Typeboolean
                                                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                            Obligations
                                                                                              ObligationsActor
                                                                                              SHALL:handleHead and Neck
                                                                                              SHALL:handleSarcoma
                                                                                              28. DiseaseExtent.sites.lung
                                                                                              Definition

                                                                                              Describes if site of metastasic disease is lung

                                                                                              Shortlung (R)
                                                                                              Comments

                                                                                              Metastasis to lung - 36770283

                                                                                              Control0..*
                                                                                              Typeboolean
                                                                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                              Obligations
                                                                                                ObligationsActor
                                                                                                SHALL:handleHead and Neck
                                                                                                SHALL:handleSarcoma
                                                                                                30. DiseaseExtent.sites.metastasisatbone
                                                                                                Definition

                                                                                                Describes if site of metastasic disease is bone

                                                                                                ShortmetastasisAtBone (R)
                                                                                                Comments

                                                                                                Metastasis to bone - 36769301

                                                                                                Control0..*
                                                                                                Typeboolean
                                                                                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                                Obligations
                                                                                                  ObligationsActor
                                                                                                  SHALL:handleHead and Neck
                                                                                                  SHALL:handleSarcoma
                                                                                                  32. DiseaseExtent.sites.liver
                                                                                                  Definition

                                                                                                  Describes if site of metastasic disease is liver

                                                                                                  Shortliver (R)
                                                                                                  Comments

                                                                                                  Metastasis to liver - 36770544

                                                                                                  Control0..*
                                                                                                  Typeboolean
                                                                                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                                  Obligations
                                                                                                    ObligationsActor
                                                                                                    SHALL:handleHead and Neck
                                                                                                    SHALL:handleSarcoma
                                                                                                    34. DiseaseExtent.sites.pleura
                                                                                                    Definition

                                                                                                    Describes if site of metastasic disease is pleura

                                                                                                    Shortpleura (R)
                                                                                                    Comments

                                                                                                    Metastasis to pleura - 35226258

                                                                                                    Control0..*
                                                                                                    Typeboolean
                                                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                                    Obligations
                                                                                                      ObligationsActor
                                                                                                      SHALL:handleHead and Neck
                                                                                                      SHALL:handleSarcoma
                                                                                                      36. DiseaseExtent.sites.peritoneum
                                                                                                      Definition

                                                                                                      Describes if site of metastasic disease is peritoneum

                                                                                                      Shortperitoneum (R)
                                                                                                      Comments

                                                                                                      Metastasis to peritoneum - 35226253

                                                                                                      Control0..*
                                                                                                      Typeboolean
                                                                                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                                      Obligations
                                                                                                        ObligationsActor
                                                                                                        SHALL:handleHead and Neck
                                                                                                        SHALL:handleSarcoma
                                                                                                        38. DiseaseExtent.sites.brain
                                                                                                        Definition

                                                                                                        Describes if site of metastasic disease is brain

                                                                                                        Shortbrain (R)
                                                                                                        Comments

                                                                                                        Metastasis to brain - 36768862

                                                                                                        Control0..*
                                                                                                        Typeboolean
                                                                                                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                                        Obligations
                                                                                                          ObligationsActor
                                                                                                          SHALL:handleHead and Neck
                                                                                                          SHALL:handleSarcoma
                                                                                                          40. DiseaseExtent.sites.otherViscera
                                                                                                          Definition

                                                                                                          Describes if site of metastasic disease is other viscera Use the generic metastasis code or a metastasis subsumed in it, 36769180

                                                                                                          Shortother viscera (R)
                                                                                                          Comments

                                                                                                          Metastasis - 36769180

                                                                                                          Control0..*
                                                                                                          Typeboolean
                                                                                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                                                          Obligations
                                                                                                            ObligationsActor
                                                                                                            SHALL:handleHead and Neck
                                                                                                            SHALL:handleSarcoma