Lithuanian Laboratory Implementation Guide, published by Lithuanian Medical Library. This guide is not an authorized publication; it is the continuous build for version 0.0.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7LT/ig-lt-lab/ and changes regularly. See the Directory of published versions

• Narrative Content
• XML
• JSON

: HER2 FISH/CISH/SISH Result Classification

Draft as of 2026-03-29

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<CodeSystem xmlns="http://hl7.org/fhir">
  <id value="her2-fish-result"/>
  <language value="en"/>
  <text>
    <status value="generated"/>
    <div xml:lang="en" lang="en"><hr/><p><b>English</b></p><hr/><p class="res-header-id"><b>Generated Narrative: CodeSystem her2-fish-result</b></p><a name="her2-fish-result"> </a><a name="hcher2-fish-result"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Language: en</p></div><p>This case-sensitive code system <code>https://tx.hl7.lt/fhir/CodeSystem/her2-fish-result</code> defines the following codes:</p><table class="codes"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td></tr><tr><td style="white-space:nowrap">amplified<a name="her2-fish-result-amplified"> </a></td><td>Amplified (HER2&gt;=4, HER2/CEP17&gt;=2)</td></tr><tr><td style="white-space:nowrap">amplified-clusters<a name="her2-fish-result-amplified-clusters"> </a></td><td>Amplified (clusters)</td></tr><tr><td style="white-space:nowrap">co-amplified<a name="her2-fish-result-co-amplified"> </a></td><td>Co-amplified (HER2&gt;=6, HER2/CEP17&lt;2)</td></tr><tr><td style="white-space:nowrap">borderline<a name="her2-fish-result-borderline"> </a></td><td>Borderline (4&lt;=HER2&lt;6, HER2/CEP17&lt;2)</td></tr><tr><td style="white-space:nowrap">monosomic<a name="her2-fish-result-monosomic"> </a></td><td>Monosomic (HER2&lt;4, HER2/CEP17&gt;=2)</td></tr><tr><td style="white-space:nowrap">negative<a name="her2-fish-result-negative"> </a></td><td>Negative (HER2&lt;4, HER2/CEP17&lt;2)</td></tr><tr><td style="white-space:nowrap">not-evaluated<a name="her2-fish-result-not-evaluated"> </a></td><td>Not to be evaluated</td></tr></table></div>
  </text>
  <url value="https://tx.hl7.lt/fhir/CodeSystem/her2-fish-result"/>
  <version value="0.0.1"/>
  <name value="Her2FishResultLtLab"/>
  <title value="HER2 FISH/CISH/SISH Result Classification"/>
  <status value="draft"/>
  <experimental value="true"/>
  <date value="2026-03-29T11:59:27+00:00"/>
  <publisher value="Lithuanian Medical Library"/>
  <contact>
    <name value="Lithuanian Medical Library"/>
    <telecom>
      <system value="url"/>
      <value value="https://medicinosnk.lt"/>
    </telecom>
    <telecom>
      <system value="email"/>
      <value value="info@medicinosnk.lt"/>
    </telecom>
  </contact>
  <description
               value="Classification of HER2 gene amplification results from FISH, CISH, or SISH molecular testing."/>
  <jurisdiction>
    <coding>
      <system value="urn:iso:std:iso:3166"/>
      <code value="LT"/>
    </coding>
  </jurisdiction>
  <caseSensitive value="true"/>
  <content value="complete"/>
  <count value="7"/>
  <concept>
    <code value="amplified"/>
    <display value="Amplified (HER2&gt;=4, HER2/CEP17&gt;=2)"/>
  </concept>
  <concept>
    <code value="amplified-clusters"/>
    <display value="Amplified (clusters)"/>
  </concept>
  <concept>
    <code value="co-amplified"/>
    <display value="Co-amplified (HER2&gt;=6, HER2/CEP17&lt;2)"/>
  </concept>
  <concept>
    <code value="borderline"/>
    <display value="Borderline (4&lt;=HER2&lt;6, HER2/CEP17&lt;2)"/>
  </concept>
  <concept>
    <code value="monosomic"/>
    <display value="Monosomic (HER2&lt;4, HER2/CEP17&gt;=2)"/>
  </concept>
  <concept>
    <code value="negative"/>
    <display value="Negative (HER2&lt;4, HER2/CEP17&lt;2)"/>
  </concept>
  <concept>
    <code value="not-evaluated"/>
    <display value="Not to be evaluated"/>
  </concept>
</CodeSystem>