Lithuanian Laboratory Implementation Guide, published by Lithuanian Medical Library. This guide is not an authorized publication; it is the continuous build for version 0.0.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7LT/ig-lt-lab/ and changes regularly. See the Directory of published versions

Profiles

Profiles

This page lists the StructureDefinition profiles defined in the Lithuanian Laboratory Implementation Guide. Use them to ensure consistent representation of laboratory results, pathology reports, and specimen data across systems.

Why these profiles matter

• For implementers and reporting: Standardised profiles enable interoperable exchange of laboratory data between LIS, EHR systems, and national repositories. Consistent structure and bindings support aggregation, analytics, and reuse without custom mappings.
• For clinicians: Profiles encode required observation codes (LOINC, SNOMED CT), units (UCUM), and result structure. This supports accurate data capture, longitudinal monitoring, and reliable use in clinical decision support.

Clinical Chemistry

Profile	Purpose
Cholesterol Total	Total cholesterol concentration in serum or plasma.
Cholesterol Non-HDL	Non-HDL cholesterol (total minus HDL), a cardiovascular risk marker.
Cholesterol HDL	HDL cholesterol concentration in serum or plasma.
Cholesterol LDL	LDL cholesterol, measured directly or by calculation.
Triglycerides	Triglyceride concentration for lipid metabolism assessment.
Lipidogram	Lipid panel grouping Total Cholesterol, LDL-C, HDL-C, and Triglycerides.
Glucose in Venous Blood	Glucose concentration in venous blood.

Glycemic Control

Profile	Purpose
HbA1c	Glycated hemoglobin (HbA1c) test for diabetes monitoring.

Renal Function

Profile	Purpose
ACR	Urine albumin-to-creatinine ratio for kidney function assessment.
Creatinine Test	Serum or plasma creatinine concentration.
eGFR	Estimated glomerular filtration rate (CKD-EPI formula).

Pathology

Profile	Purpose
Pathology Order	ServiceRequest for pathology laboratory orders.
Pathology Composition	Synoptic pathology document with LOINC-coded sections (Pre-Analytic, Macro, Micro, Synthesis).
Pathology Report	DiagnosticReport for pathology laboratory results.
Prostate Cancer Condition	Prostate cancer diagnosis with TNM staging and morphology.
Biopsy Procedure	Biopsy procedure for histopathological examination.
HER2 Receptor Status	HER2 receptor expression status (IHC/molecular).
HER2 FISH/CISH/SISH	HER2 gene amplification molecular test with HER2 average, CEP17 average, ratio, and classification.
Estrogen Receptor Status	IHC estrogen receptor (ER) status with expression level and percentage.
Progesterone Receptor Status	IHC progesterone receptor (PR) status with expression level and percentage.
Ki-67 Proliferation Index	Ki-67 proliferation index as percentage of positive tumor cells.

Specimen

Profile	Purpose
Specimen	Laboratory specimen with identifier, collection, and processing details.
Specimen: Tissue Block	Paraffin-embedded tissue block derived from a parent specimen.
Substance: Specimen Additive	Additive substance used in specimen collection or processing.
Specimen Adequacy	Observation assessing whether a specimen is adequate for evaluation.
Specimen Measurement	Physical measurements of a specimen (dimensions, weight, lymph node count).
Tumor Measurement	Tumor measurement observations.
Tumor Observable	Tumor observable component observations.

Extension

Extension	Purpose
specimen-received-by	Practitioner who received the specimen at the laboratory.

For terminology used by these profiles, see Terminology; for sample instances, see Examples.