Introduction

In the phenopacket-schema, an Individual can have zero to many MedicalAction messages. A MedicalAction can refer to a Procedure, Treatment, RadiationTherapy, or TherapeuticRegimen. The Treatment message represents treatment with an agent such as a drug (pharmaceutical agent), broadly defined as prescription and over-the-counter medicines, vaccines, and large-molecule biologic therapies.

The FHIR MedicationAdministration and the GA4GH phenopacket-schema Treatment.

We represent the GA4GH Treatment element by profiling a FHIR MedicationAdministration.

1. In the GA4GH phenopacket, the agent element is a required OntologyClass that denotes the drug or therapeutic agent. It corresponds to the medication element of MedicationAdministration.

2. In the GA4GH phenopacket, the route_of_administration element is an optional OntologyClass that denotes how was the drug administered, e.g., by mouth or intravenously. It corresponds to the dosage.route element of MedicationAdministration.

3. In the GA4GH phenopacket, the dose_intervals element is a potentially empty list of DoseIntervals. FHIR models the dosage in the dosage element and the time interval in which a given dose is administered with the effective element. Software for transforming FHIR to GA4GH phenopacket should extract information from both fields to instantiate DoseIntervals. In the In the GA4GH phenopacket, one Treatment can contain a list of multiple DoseIntervals. In FHIR, multiple MedicationAdministration elements would be used. Software for transforming FHIR to GA4GH phenopacket is allowed to combine data into a single Treatment with multiple DoseIntervals.

4. In the GA4GH phenopacket, the drug_type element is an enumeration (UNKNOWN_DRUG_TYPE, PRESCRIPTION, EHR_MEDICATION_LIST,ADMINISTRATION_RELATED_TO_PROCEDURE). This corresponds to the category field of MedicationAdministration.

• Differential Table
• Key Elements Table
• Snapshot Table
• Statistics/References
• All

This structure is derived from MedicationAdministration

Name	Flags	Card.	Type	Description & Constraints
MedicationAdministration		0..*	MedicationAdministration	Administration of medication to a patient
category	S	0..1	CodeableConcept	Corresponds to drug_type (GA4GH)
medication[x]	S	1..1	CodeableConcept, Reference(Medication)	What was administered
effective[x]	S	1..1	dateTime, Period	Information from effective and dosage is required for dose_intervals (GA4GH)
dosage	S	0..1	BackboneElement	Information from effective and dosage is required for dose_intervals (GA4GH)
route	S	0..1	CodeableConcept	Corresponds to route_of_administration (GA4GH)
Documentation for this format

Name	Flags	Card.	Type	Description & Constraints
MedicationAdministration		0..*	MedicationAdministration	Administration of medication to a patient
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
status	?!Σ	1..1	code	in-progress | not-done | on-hold | completed | entered-in-error | stopped | unknown Binding: MedicationAdministration Status Codes (required): A set of codes indicating the current status of a MedicationAdministration.
category	S	0..1	CodeableConcept	Corresponds to drug_type (GA4GH) Binding: MedicationAdministration Category Codes (preferred): A coded concept describing where the medication administered is expected to occur.
medication[x]	SΣ	1..1		What was administered Binding: SNOMEDCTMedicationCodes (example): Codes identifying substance or product that can be administered.
medicationCodeableConcept			CodeableConcept
medicationReference			Reference(Medication)
subject	Σ	1..1	Reference(Patient | Group)	Who received medication
effective[x]	SΣ	1..1		Information from effective and dosage is required for dose_intervals (GA4GH)
effectiveDateTime			dateTime
effectivePeriod			Period
dosage	SC	0..1	BackboneElement	Information from effective and dosage is required for dose_intervals (GA4GH) mad-1: SHALL have at least one of dosage.dose or dosage.rate[x]
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
route	S	0..1	CodeableConcept	Corresponds to route_of_administration (GA4GH) Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationAdministration.status	required	MedicationAdministration Status Codes http://hl7.org/fhir/ValueSet/medication-admin-status|4.0.1 from the FHIR Standard
MedicationAdministration.category	preferred	MedicationAdministration Category Codes http://hl7.org/fhir/ValueSet/medication-admin-category from the FHIR Standard
MedicationAdministration.medication[x]	example	SNOMEDCTMedicationCodes http://hl7.org/fhir/ValueSet/medication-codes from the FHIR Standard
MedicationAdministration.dosage.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationAdministration	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationAdministration	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationAdministration	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationAdministration	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationAdministration	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
mad-1	error	MedicationAdministration.dosage	SHALL have at least one of dosage.dose or dosage.rate[x] : dose.exists() or rate.exists()

Name	Flags	Card.	Type	Description & Constraints
MedicationAdministration		0..*	MedicationAdministration	Administration of medication to a patient
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier		0..*	Identifier	External identifier
instantiates	Σ	0..*	uri	Instantiates protocol or definition
partOf	Σ	0..*	Reference(MedicationAdministration | Procedure)	Part of referenced event
status	?!Σ	1..1	code	in-progress | not-done | on-hold | completed | entered-in-error | stopped | unknown Binding: MedicationAdministration Status Codes (required): A set of codes indicating the current status of a MedicationAdministration.
statusReason		0..*	CodeableConcept	Reason administration not performed Binding: SNOMEDCTReasonMedicationNotGivenCodes (example): A set of codes indicating the reason why the MedicationAdministration is negated.
category	S	0..1	CodeableConcept	Corresponds to drug_type (GA4GH) Binding: MedicationAdministration Category Codes (preferred): A coded concept describing where the medication administered is expected to occur.
medication[x]	SΣ	1..1		What was administered Binding: SNOMEDCTMedicationCodes (example): Codes identifying substance or product that can be administered.
medicationCodeableConcept			CodeableConcept
medicationReference			Reference(Medication)
subject	Σ	1..1	Reference(Patient | Group)	Who received medication
context		0..1	Reference(Encounter | EpisodeOfCare)	Encounter or Episode of Care administered as part of
supportingInformation		0..*	Reference(Resource)	Additional information to support administration
effective[x]	SΣ	1..1		Information from effective and dosage is required for dose_intervals (GA4GH)
effectiveDateTime			dateTime
effectivePeriod			Period
performer	Σ	0..*	BackboneElement	Who performed the medication administration and what they did
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
function		0..1	CodeableConcept	Type of performance Binding: MedicationAdministration Performer Function Codes (example): A code describing the role an individual played in administering the medication.
actor	Σ	1..1	Reference(Practitioner | PractitionerRole | Patient | RelatedPerson | Device)	Who performed the medication administration
reasonCode		0..*	CodeableConcept	Reason administration performed Binding: ReasonMedicationGivenCodes (example): A set of codes indicating the reason why the MedicationAdministration was made.
reasonReference		0..*	Reference(Condition | Observation | DiagnosticReport)	Condition or observation that supports why the medication was administered
request		0..1	Reference(MedicationRequest)	Request administration performed against
device		0..*	Reference(Device)	Device used to administer
note		0..*	Annotation	Information about the administration
dosage	SC	0..1	BackboneElement	Information from effective and dosage is required for dose_intervals (GA4GH) mad-1: SHALL have at least one of dosage.dose or dosage.rate[x]
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
text		0..1	string	Free text dosage instructions e.g. SIG
site		0..1	CodeableConcept	Body site administered to Binding: SNOMEDCTAnatomicalStructureForAdministrationSiteCodes (example): A coded concept describing the site location the medicine enters into or onto the body.
route	S	0..1	CodeableConcept	Corresponds to route_of_administration (GA4GH) Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
method		0..1	CodeableConcept	How drug was administered Binding: SNOMEDCTAdministrationMethodCodes (example): A coded concept describing the technique by which the medicine is administered.
dose		0..1	SimpleQuantity	Amount of medication per dose
rate[x]		0..1		Dose quantity per unit of time
rateRatio			Ratio
rateQuantity			Quantity(SimpleQuantity)
eventHistory		0..*	Reference(Provenance)	A list of events of interest in the lifecycle
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationAdministration.language	preferred	CommonLanguages Additional Bindings Purpose AllLanguages Max Binding http://hl7.org/fhir/ValueSet/languages from the FHIR Standard
MedicationAdministration.status	required	MedicationAdministration Status Codes http://hl7.org/fhir/ValueSet/medication-admin-status|4.0.1 from the FHIR Standard
MedicationAdministration.statusReason	example	SNOMEDCTReasonMedicationNotGivenCodes http://hl7.org/fhir/ValueSet/reason-medication-not-given-codes from the FHIR Standard
MedicationAdministration.category	preferred	MedicationAdministration Category Codes http://hl7.org/fhir/ValueSet/medication-admin-category from the FHIR Standard
MedicationAdministration.medication[x]	example	SNOMEDCTMedicationCodes http://hl7.org/fhir/ValueSet/medication-codes from the FHIR Standard
MedicationAdministration.performer.function	example	MedicationAdministration Performer Function Codes http://hl7.org/fhir/ValueSet/med-admin-perform-function from the FHIR Standard
MedicationAdministration.reasonCode	example	ReasonMedicationGivenCodes http://hl7.org/fhir/ValueSet/reason-medication-given-codes from the FHIR Standard
MedicationAdministration.dosage.site	example	SNOMEDCTAnatomicalStructureForAdministrationSiteCodes http://hl7.org/fhir/ValueSet/approach-site-codes from the FHIR Standard
MedicationAdministration.dosage.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard
MedicationAdministration.dosage.method	example	SNOMEDCTAdministrationMethodCodes http://hl7.org/fhir/ValueSet/administration-method-codes from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationAdministration	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationAdministration	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationAdministration	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationAdministration	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationAdministration	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
mad-1	error	MedicationAdministration.dosage	SHALL have at least one of dosage.dose or dosage.rate[x] : dose.exists() or rate.exists()

Differential View

This structure is derived from MedicationAdministration

Name	Flags	Card.	Type	Description & Constraints
MedicationAdministration		0..*	MedicationAdministration	Administration of medication to a patient
category	S	0..1	CodeableConcept	Corresponds to drug_type (GA4GH)
medication[x]	S	1..1	CodeableConcept, Reference(Medication)	What was administered
effective[x]	S	1..1	dateTime, Period	Information from effective and dosage is required for dose_intervals (GA4GH)
dosage	S	0..1	BackboneElement	Information from effective and dosage is required for dose_intervals (GA4GH)
route	S	0..1	CodeableConcept	Corresponds to route_of_administration (GA4GH)
Documentation for this format

Key Elements View

Name	Flags	Card.	Type	Description & Constraints
MedicationAdministration		0..*	MedicationAdministration	Administration of medication to a patient
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
status	?!Σ	1..1	code	in-progress | not-done | on-hold | completed | entered-in-error | stopped | unknown Binding: MedicationAdministration Status Codes (required): A set of codes indicating the current status of a MedicationAdministration.
category	S	0..1	CodeableConcept	Corresponds to drug_type (GA4GH) Binding: MedicationAdministration Category Codes (preferred): A coded concept describing where the medication administered is expected to occur.
medication[x]	SΣ	1..1		What was administered Binding: SNOMEDCTMedicationCodes (example): Codes identifying substance or product that can be administered.
medicationCodeableConcept			CodeableConcept
medicationReference			Reference(Medication)
subject	Σ	1..1	Reference(Patient | Group)	Who received medication
effective[x]	SΣ	1..1		Information from effective and dosage is required for dose_intervals (GA4GH)
effectiveDateTime			dateTime
effectivePeriod			Period
dosage	SC	0..1	BackboneElement	Information from effective and dosage is required for dose_intervals (GA4GH) mad-1: SHALL have at least one of dosage.dose or dosage.rate[x]
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
route	S	0..1	CodeableConcept	Corresponds to route_of_administration (GA4GH) Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationAdministration.status	required	MedicationAdministration Status Codes http://hl7.org/fhir/ValueSet/medication-admin-status|4.0.1 from the FHIR Standard
MedicationAdministration.category	preferred	MedicationAdministration Category Codes http://hl7.org/fhir/ValueSet/medication-admin-category from the FHIR Standard
MedicationAdministration.medication[x]	example	SNOMEDCTMedicationCodes http://hl7.org/fhir/ValueSet/medication-codes from the FHIR Standard
MedicationAdministration.dosage.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationAdministration	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationAdministration	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationAdministration	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationAdministration	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationAdministration	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
mad-1	error	MedicationAdministration.dosage	SHALL have at least one of dosage.dose or dosage.rate[x] : dose.exists() or rate.exists()

Snapshot View

Name	Flags	Card.	Type	Description & Constraints
MedicationAdministration		0..*	MedicationAdministration	Administration of medication to a patient
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier		0..*	Identifier	External identifier
instantiates	Σ	0..*	uri	Instantiates protocol or definition
partOf	Σ	0..*	Reference(MedicationAdministration | Procedure)	Part of referenced event
status	?!Σ	1..1	code	in-progress | not-done | on-hold | completed | entered-in-error | stopped | unknown Binding: MedicationAdministration Status Codes (required): A set of codes indicating the current status of a MedicationAdministration.
statusReason		0..*	CodeableConcept	Reason administration not performed Binding: SNOMEDCTReasonMedicationNotGivenCodes (example): A set of codes indicating the reason why the MedicationAdministration is negated.
category	S	0..1	CodeableConcept	Corresponds to drug_type (GA4GH) Binding: MedicationAdministration Category Codes (preferred): A coded concept describing where the medication administered is expected to occur.
medication[x]	SΣ	1..1		What was administered Binding: SNOMEDCTMedicationCodes (example): Codes identifying substance or product that can be administered.
medicationCodeableConcept			CodeableConcept
medicationReference			Reference(Medication)
subject	Σ	1..1	Reference(Patient | Group)	Who received medication
context		0..1	Reference(Encounter | EpisodeOfCare)	Encounter or Episode of Care administered as part of
supportingInformation		0..*	Reference(Resource)	Additional information to support administration
effective[x]	SΣ	1..1		Information from effective and dosage is required for dose_intervals (GA4GH)
effectiveDateTime			dateTime
effectivePeriod			Period
performer	Σ	0..*	BackboneElement	Who performed the medication administration and what they did
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
function		0..1	CodeableConcept	Type of performance Binding: MedicationAdministration Performer Function Codes (example): A code describing the role an individual played in administering the medication.
actor	Σ	1..1	Reference(Practitioner | PractitionerRole | Patient | RelatedPerson | Device)	Who performed the medication administration
reasonCode		0..*	CodeableConcept	Reason administration performed Binding: ReasonMedicationGivenCodes (example): A set of codes indicating the reason why the MedicationAdministration was made.
reasonReference		0..*	Reference(Condition | Observation | DiagnosticReport)	Condition or observation that supports why the medication was administered
request		0..1	Reference(MedicationRequest)	Request administration performed against
device		0..*	Reference(Device)	Device used to administer
note		0..*	Annotation	Information about the administration
dosage	SC	0..1	BackboneElement	Information from effective and dosage is required for dose_intervals (GA4GH) mad-1: SHALL have at least one of dosage.dose or dosage.rate[x]
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
text		0..1	string	Free text dosage instructions e.g. SIG
site		0..1	CodeableConcept	Body site administered to Binding: SNOMEDCTAnatomicalStructureForAdministrationSiteCodes (example): A coded concept describing the site location the medicine enters into or onto the body.
route	S	0..1	CodeableConcept	Corresponds to route_of_administration (GA4GH) Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
method		0..1	CodeableConcept	How drug was administered Binding: SNOMEDCTAdministrationMethodCodes (example): A coded concept describing the technique by which the medicine is administered.
dose		0..1	SimpleQuantity	Amount of medication per dose
rate[x]		0..1		Dose quantity per unit of time
rateRatio			Ratio
rateQuantity			Quantity(SimpleQuantity)
eventHistory		0..*	Reference(Provenance)	A list of events of interest in the lifecycle
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationAdministration.language	preferred	CommonLanguages Additional Bindings Purpose AllLanguages Max Binding http://hl7.org/fhir/ValueSet/languages from the FHIR Standard
MedicationAdministration.status	required	MedicationAdministration Status Codes http://hl7.org/fhir/ValueSet/medication-admin-status|4.0.1 from the FHIR Standard
MedicationAdministration.statusReason	example	SNOMEDCTReasonMedicationNotGivenCodes http://hl7.org/fhir/ValueSet/reason-medication-not-given-codes from the FHIR Standard
MedicationAdministration.category	preferred	MedicationAdministration Category Codes http://hl7.org/fhir/ValueSet/medication-admin-category from the FHIR Standard
MedicationAdministration.medication[x]	example	SNOMEDCTMedicationCodes http://hl7.org/fhir/ValueSet/medication-codes from the FHIR Standard
MedicationAdministration.performer.function	example	MedicationAdministration Performer Function Codes http://hl7.org/fhir/ValueSet/med-admin-perform-function from the FHIR Standard
MedicationAdministration.reasonCode	example	ReasonMedicationGivenCodes http://hl7.org/fhir/ValueSet/reason-medication-given-codes from the FHIR Standard
MedicationAdministration.dosage.site	example	SNOMEDCTAnatomicalStructureForAdministrationSiteCodes http://hl7.org/fhir/ValueSet/approach-site-codes from the FHIR Standard
MedicationAdministration.dosage.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard
MedicationAdministration.dosage.method	example	SNOMEDCTAdministrationMethodCodes http://hl7.org/fhir/ValueSet/administration-method-codes from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationAdministration	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationAdministration	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationAdministration	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationAdministration	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationAdministration	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
mad-1	error	MedicationAdministration.dosage	SHALL have at least one of dosage.dose or dosage.rate[x] : dose.exists() or rate.exists()

This structure is derived from MedicationAdministration

Summary

Must-Support: 5 elements