Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot3 - STU 1 Ballot 3 World

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: PICO: Intensive versus standard blood-pressure control for major adverse cardiovascular events in adults at increased cardiovascular risk

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    <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: Group 588218</b></p><a name="588218"> </a><a name="hc588218"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">version: 7; Last updated: 2026-08-15 16:32:10+0000</p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-pico-specification.html">PICOSpecification</a></p></div><p><b>Artifact Author</b>: Khalid Shahin: </p><p><b>ArtifactRecorder</b>: Khalid Shahin: </p><p><b>CiteAs</b>: </p><div><p>PICO: Intensive versus standard blood-pressure control for major adverse cardiovascular events in adults at increased cardiovascular risk [Database Entry: FHIR Group Resource]. Contributors: Khalid Shahin [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 588218. Revised 2026-08-15. Available at: https://fevir.net/resources/Group/588218. Computable resource at: https://fevir.net/resources/Group/588218#json.</p>
</div><p><b>ArtifactPublicationStatus</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/cited-artifact-status-type active}">Active</span></p><p><b>url</b>: <a href="https://fevir.net/resources/Group/588218">https://fevir.net/resources/Group/588218</a></p><p><b>identifier</b>: FEvIR Object Identifier/588218, <code>http://example.org/fhir/sid/pico-register</code>/PICO-2026-0142 (use: official, )</p><p><b>title</b>: PICO: Intensive versus standard blood-pressure control for major adverse cardiovascular events in adults at increased cardiovascular risk</p><p><b>status</b>: Active</p><p><b>publisher</b>: Computable Publishing LLC</p><p><b>contact</b>: <a href="mailto:support@computablepublishing.com">support@computablepublishing.com</a></p><p><b>description</b>: </p><div><p>This Group Resource is referenced in an example for the EBMonFHIR Implementation Guide.</p>
</div><p><b>copyright</b>: </p><div><p>Copyright the Authors else Computable Publishing LLC. Noncommercial use permitted with CC BY-NC-SA 4.0 (https://creativecommons.org/licenses/by-nc-sa/4.0/). Commercial use permitted as agreed in Terms of Use (https://fevir.net/termsofuse).</p>
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</div></blockquote><blockquote><p><b>characteristic</b></p><p><b>code</b>: <span title="Codes:{https://fevir.net/resources/CodeSystem/179423 comparator}">Comparator</span></p><p><b>value</b>: <span title="Codes:">Standard blood-pressure control: antihypertensive therapy titrated to a systolic target below 140 mmHg</span></p><p><b>exclude</b>: false</p><p><b>description</b>: </p><div><p>Any antihypertensive regimen titrated to achieve and maintain a systolic blood pressure below 140 mmHg, reflecting the guideline-recommended target in force at the time the question was formulated.</p>
</div></blockquote><blockquote><p><b>characteristic</b></p><p><b>code</b>: <span title="Codes:{https://fevir.net/resources/CodeSystem/179423 outcome-measure}">Outcome Measure</span></p><p><b>value</b>: <span title="Codes:">Major adverse cardiovascular events: composite of myocardial infarction, other acute coronary syndrome, stroke, acute decompensated heart failure, or death from cardiovascular causes</span></p><p><b>exclude</b>: false</p><p><b>description</b>: </p><div><p>Time to first occurrence of any component of the composite, adjudicated by a committee unaware of treatment assignment. Individual components are reported as separate outcome measures in the evidence report.</p>
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