Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot3 - STU 1 Ballot 3 World

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: Example of statistical model expression

Raw json | Download

{
  "resourceType" : "Evidence",
  "id" : "587629",
  "meta" : {
    "versionId" : "4",
    "lastUpdated" : "2026-08-03T18:52:42.905Z",
    "profile" : [
      🔗 "http://hl7.org/fhir/uv/ebm/StructureDefinition/statistic-model"
    ]
  },
  "language" : "en",
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Evidence 587629</b></p><a name=\"587629\"> </a><a name=\"hc587629\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 4; Last updated: 2026-08-03 18:52:42+0000</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-statistic-model.html\">StatisticModel</a></p></div><p><b>ArtifactPublicationStatus</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/cited-artifact-status-type active}\">Active</span></p><p><b>url</b>: <a href=\"https://fevir.net/resources/Evidence/587629\">https://fevir.net/resources/Evidence/587629</a></p><p><b>identifier</b>: FEvIR Object Identifier/587629</p><p><b>name</b>: Example_of_statistical_model_expression</p><p><b>title</b>: Example of statistical model expression</p><p><b>citeAs</b>: </p><div><p>Example of statistical model expression [Database Entry: FHIR Evidence Resource]. Contributors: Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 587629. Revised 2026-08-03. Available at: https://fevir.net/resources/Evidence/587629. Computable resource at: https://fevir.net/resources/Evidence/587629#json.</p>\n</div><p><b>status</b>: Active</p><p><b>author</b>: Brian S. Alper, MD, MSPH: </p><p><b>publisher</b>: Computable Publishing LLC</p><p><b>contact</b>: <a href=\"mailto:support@computablepublishing.com\">support@computablepublishing.com</a></p><p><b>copyright</b>: </p><div><p>Copyright the Authors else Computable Publishing LLC. Noncommercial use permitted with CC BY-NC-SA 4.0 (https://creativecommons.org/licenses/by-nc-sa/4.0/). Commercial use permitted as agreed in Terms of Use (https://fevir.net/termsofuse).</p>\n</div><p><b>description</b>: </p><div><p>This is an example of madeup Evidence to demonstrate the StatisticalModelExpression extension.</p>\n</div><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>Patients with diabetes</p>\n</div><p><b>variableRole</b>: Population</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>GroupAssignment: Treatment vs. Control</p>\n</div><p><b>variableRole</b>: Exposure</p><p><b>comparatorCategory</b>: Control</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>The primary outcome</p>\n</div><p><b>variableRole</b>: Outcome</p></blockquote><blockquote><p><b>statistic</b></p><p><b>StatisticModelExpression</b>: <span title=\"text/r\"><code>glm(Outcome ~ Treatment + Baseline_A1C + Age, family = binomial(link = 'logit'))</code></span>(&quot;Logistic regression formula used to calculate the adjusted odds ratio for the primary endpoint.&quot;)</p><p><b>description</b>: </p><div><p>Adjusted Odds Ratio for primary outcome 1.45 (95% CI .12 to 1.88)</p>\n</div><p><b>statisticType</b>: <span title=\"Codes:{https://fevir.net/sevco STATO:0000182}\">odds ratio</span></p><p><b>quantity</b>: 1.45</p><h3>AttributeEstimates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/attribute-estimate-type C53324}\">Confidence interval</span></td><td>1.12-1.88</td></tr></table></blockquote></div>"
  },
  "extension" : [
    {
      "url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status",
      "valueCodeableConcept" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/cited-artifact-status-type",
            "code" : "active",
            "display" : "Active"
          }
        ]
      }
    }
  ],
  "url" : "https://fevir.net/resources/Evidence/587629",
  "identifier" : [
    {
      "type" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "ACSN",
            "display" : "Accession ID"
          }
        ],
        "text" : "FEvIR Object Identifier"
      },
      "system" : "https://fevir.net/FOI",
      "value" : "587629",
      "assigner" : {
        "display" : "Computable Publishing LLC"
      }
    }
  ],
  "name" : "Example_of_statistical_model_expression",
  "title" : "Example of statistical model expression",
  "citeAs" : "Example of statistical model expression [Database Entry: FHIR Evidence Resource]. Contributors: Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 587629. Revised 2026-08-03. Available at: https://fevir.net/resources/Evidence/587629. Computable resource at: https://fevir.net/resources/Evidence/587629#json.",
  "status" : "active",
  "author" : [
    {
      "name" : "Brian S. Alper, MD, MSPH"
    }
  ],
  "publisher" : "Computable Publishing LLC",
  "contact" : [
    {
      "telecom" : [
        {
          "system" : "email",
          "value" : "support@computablepublishing.com"
        }
      ]
    }
  ],
  "copyright" : "Copyright the Authors else Computable Publishing LLC. Noncommercial use permitted with CC BY-NC-SA 4.0 (https://creativecommons.org/licenses/by-nc-sa/4.0/). Commercial use permitted as agreed in Terms of Use (https://fevir.net/termsofuse).",
  "description" : "This is an example of madeup Evidence to demonstrate the StatisticalModelExpression extension.",
  "variableDefinition" : [
    {
      "description" : "Patients with diabetes",
      "variableRole" : "population"
    },
    {
      "description" : "GroupAssignment: Treatment vs. Control",
      "variableRole" : "exposure",
      "comparatorCategory" : "Control"
    },
    {
      "description" : "The primary outcome",
      "variableRole" : "outcome"
    }
  ],
  "statistic" : [
    {
      "extension" : [
        {
          "url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/statistic-model-expression",
          "valueExpression" : {
            "description" : "Logistic regression formula used to calculate the adjusted odds ratio for the primary endpoint.",
            "language" : "text/r",
            "expression" : "glm(Outcome ~ Treatment + Baseline_A1C + Age, family = binomial(link = 'logit'))"
          }
        }
      ],
      "description" : "Adjusted Odds Ratio for primary outcome 1.45 (95% CI .12 to 1.88)",
      "statisticType" : {
        "coding" : [
          {
            "system" : "https://fevir.net/sevco",
            "code" : "STATO:0000182",
            "display" : "odds ratio"
          }
        ]
      },
      "quantity" : {
        "value" : 1.45
      },
      "attributeEstimate" : [
        {
          "type" : {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/attribute-estimate-type",
                "code" : "C53324",
                "display" : "Confidence interval"
              }
            ]
          },
          "range" : {
            "low" : {
              "value" : 1.12
            },
            "high" : {
              "value" : 1.88
            }
          }
        }
      ]
    }
  ]
}