Evidence Based Medicine on FHIR Implementation Guide
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Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: SummaryOfFindings: Bariatric Surgery Summary of Findings Example for GIN 2022 - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Composition ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "104215"] ; # 
  fhir:meta [
fhir:versionId [ fhir:v "32" ] ;
fhir:lastUpdated [ fhir:v "2024-10-31T14:34:35.665Z"^^xsd:dateTime ] ;
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/summary-of-findings"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/uv/ebm/StructureDefinition/summary-of-findings>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-description"^^xsd:anyURI ] ;
fhir:value [ fhir:v "Example of SummaryOfFindings Profile of Composition Resource." ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-copyright"^^xsd:anyURI ] ;
fhir:value [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/" ]
  ] ) ; # 
  fhir:url [ fhir:v "https://fevir.net/resources/Composition/104215"^^xsd:anyURI] ; # 
  fhir:identifier ( [
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ACSN" ] ;
fhir:display [ fhir:v "Accession ID" ]       ] ) ;
fhir:text [ fhir:v "FEvIR Object Identifier" ]     ] ;
fhir:system [ fhir:v "urn:ietf:rfc:3986"^^xsd:anyURI ] ;
fhir:value [ fhir:v "https://fevir.net/FOI/104215" ] ;
fhir:assigner [
fhir:display [ fhir:v "Computable Publishing LLC" ]     ]
  ] ) ; # 
  fhir:status [ fhir:v "final"] ; # 
  fhir:type [
    ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "SummaryOfFindings" ] ;
fhir:display [ fhir:v "SummaryOfFindings" ]     ] ) ;
fhir:text [ fhir:v "Summary of Findings" ]
  ] ; # 
  fhir:subject ( [
fhir:reference [ fhir:v "Group/179562" ] ;
fhir:type [ fhir:v "Group"^^xsd:anyURI ] ;
fhir:display [ fhir:v "EvidenceReportSubject: Clinical Outcomes for Effects of Bariatric Surgery" ]
  ] ) ; # 
  fhir:date [ fhir:v "2024-10-31T14:34:35.665Z"^^xsd:dateTime] ; # 
  fhir:author ( [
fhir:type [ fhir:v "Practitioner"^^xsd:anyURI ] ;
fhir:display [ fhir:v "Brian S. Alper" ]
  ] ) ; # 
  fhir:title [ fhir:v "SummaryOfFindings: Bariatric Surgery Summary of Findings Example for GIN 2022"] ; # 
  fhir:custodian [
fhir:display [ fhir:v "Computable Publishing LLC" ]
  ] ; # 
  fhir:relatesTo ( [
fhir:type [ fhir:v "cite-as" ] ;
fhir:label [ fhir:v "Cite as" ] ;
fhir:citation [ fhir:v "SummaryOfFindings: Bariatric Surgery Summary of Findings Example for GIN 2022 [Database Entry: FHIR Composition Resource]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 104215. Revised 2024-08-07. Available at: https://fevir.net/resources/Composition/104215. Computable resource at: https://fevir.net/FLI/DocumentForComposition104215." ]
  ] ) ; # 
  fhir:section ( [
fhir:title [ fhir:v "Column Headers" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "column-headers" ] ;
fhir:display [ fhir:v "Column Headers" ]       ] )     ] ;
    ( fhir:entry [
fhir:reference [ fhir:v "Composition/104213" ] ;
fhir:type [ fhir:v "Composition"^^xsd:anyURI ] ;
fhir:display [ fhir:v "EvidenceMap: Bariatric Surgery Summary of Findings Example for GIN 2022" ]     ] ) ;
    ( fhir:section [
fhir:title [ fhir:v "Outcome" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "outcome-measure" ] ;
fhir:display [ fhir:v "Outcome Measure" ]         ] )       ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Outcome</div>"       ]     ] [
fhir:title [ fhir:v "Sample Size" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "sample-size" ] ;
fhir:display [ fhir:v "Sample Size" ]         ] )       ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Sample size: # studies, # participants, # counted, # events</div>"       ]     ] [
fhir:title [ fhir:v "Result Without Treatment" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-comparator-alone" ] ;
fhir:display [ fhir:v "Result with comparator alone" ]         ] )       ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Result without bariatric surgery</div>"       ]     ] [
fhir:title [ fhir:v "Result With Treatment--Observed" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone" ] ;
fhir:display [ fhir:v "Result with intervention alone" ]         ] )       ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Result with bariatric surgery</div>"       ]     ] [
fhir:title [ fhir:v "Result With Treatment--Derived" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ;
fhir:display [ fhir:v "Result with intervention alone (calculated)" ]         ] ) ;
fhir:text [ fhir:v "calculated value derived from the control group and effect estimate" ]       ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Result with bariatric surgery (calculated)</div>"       ]     ] [
fhir:title [ fhir:v "Effect Estimate" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ;
fhir:display [ fhir:v "Result with intervention vs. comparator" ]         ] )       ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Effect Estimate (Relative effect)</div>"       ]     ] [
fhir:title [ fhir:v "Certainty of Evidence" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "certainty-of-evidence" ] ;
fhir:display [ fhir:v "Certainty of Evidence" ]         ] )       ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Certainty of finding (Quality of evidence)</div>"       ]     ] [
fhir:title [ fhir:v "Assertion" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "assertion" ] ;
fhir:display [ fhir:v "Assertion" ]         ] )       ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">What this means</div>"       ]     ] )
  ] [
fhir:title [ fhir:v "Summary of Findings" ] ;
fhir:code [
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "summary-of-findings" ] ;
fhir:display [ fhir:v "Summary of Findings" ]       ] )     ] ;
fhir:emptyReason [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/list-empty-reason"^^xsd:anyURI ] ;
fhir:code [ fhir:v "notstarted" ] ;
fhir:display [ fhir:v "Not Started" ]       ] )     ] ;
    ( fhir:section [
fhir:title [ fhir:v "All-cause mortality" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "summary-of-findings-entry-for-a-single-outcome" ] ;
fhir:display [ fhir:v "Summary of findings entry for a single outcome" ]         ] )       ] ;
fhir:focus [
fhir:reference [ fhir:v "EvidenceVariable/49217" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: All-cause mortality" ]       ] ;
fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"       ] ;
      ( fhir:section [
fhir:title [ fhir:v "Outcome" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "outcome-measure" ] ;
fhir:display [ fhir:v "Outcome Measure" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">All-cause mortality</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "EvidenceVariable/49217" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: All-cause mortality" ]         ] )       ] [
fhir:title [ fhir:v "Sample Size" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "sample-size" ] ;
fhir:display [ fhir:v "Sample Size" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">21 studies, 397002 participants</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/49328" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: All-cause mortality effect of bariatric surgery in 2022 meta-analysis" ]         ] )       ] [
fhir:title [ fhir:v "Result Without Treatment" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-comparator-alone" ] ;
fhir:display [ fhir:v "Result with comparator alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">5% (estimated); specific summary evidence not reported</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104384" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: All-cause mortality without bariatric surgery in 2022 meta-analysis" ]         ] )       ] [
fhir:title [ fhir:v "Result With Treatment--Observed" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone" ] ;
fhir:display [ fhir:v "Result with intervention alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Not reported</div>"         ]       ] [
fhir:title [ fhir:v "Result With Treatment--Derived" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ;
fhir:display [ fhir:v "Result with intervention alone (calculated)" ]           ] ) ;
fhir:text [ fhir:v "calculated value derived from the control group and effect estimate" ]         ] ;
fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Not reported</div>"         ]       ] [
fhir:title [ fhir:v "Effect Estimate" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ;
fhir:display [ fhir:v "Result with intervention vs. comparator" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Hazard Ratio 0.55 (95% confidence interval 0.49 to 0.62)</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/49328" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: All-cause mortality effect of bariatric surgery in 2022 meta-analysis" ]         ] )       ] [
fhir:title [ fhir:v "Certainty of Evidence" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "certainty-of-evidence" ] ;
fhir:display [ fhir:v "Certainty of Evidence" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Low quality</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/49328" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: All-cause mortality effect of bariatric surgery in 2022 meta-analysis" ]         ] )       ] [
fhir:title [ fhir:v "Assertion" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "assertion" ] ;
fhir:display [ fhir:v "Assertion" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">The present systematic review and meta-analysis suggests that bariatric surgery is associated with reduced all-cause and CV mortality.</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/49328" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: All-cause mortality effect of bariatric surgery in 2022 meta-analysis" ]         ] )       ] )     ] [
fhir:title [ fhir:v "Nonfatal myocardial infarction or stroke" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "summary-of-findings-entry-for-a-single-outcome" ] ;
fhir:display [ fhir:v "Summary of findings entry for a single outcome" ]         ] )       ] ;
fhir:focus [
fhir:reference [ fhir:v "EvidenceVariable/104097" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: Nonfatal myocardial infarction or stroke" ]       ] ;
fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"       ] ;
      ( fhir:section [
fhir:title [ fhir:v "Outcome" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "outcome-measure" ] ;
fhir:display [ fhir:v "Outcome Measure" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Nonfatal myocardial infarction or stroke</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "EvidenceVariable/104097" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: Nonfatal myocardial infarction or stroke" ]         ] )       ] [
fhir:title [ fhir:v "Sample Size" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "sample-size" ] ;
fhir:display [ fhir:v "Sample Size" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">1 study, 4,047 participants, 4,047 counted, 359 events</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104098" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study" ]         ] )       ] [
fhir:title [ fhir:v "Result Without Treatment" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-comparator-alone" ] ;
fhir:display [ fhir:v "Result with comparator alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">188 out of 2,037 observed with percentage of: 9.2%</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104397" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: Myocardial infarction or stroke without bariatric surgery (Control Group) in Swedish Obese Subjects (SOS) study" ]         ] )       ] [
fhir:title [ fhir:v "Result With Treatment--Observed" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone" ] ;
fhir:display [ fhir:v "Result with intervention alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">171 out of 2,010 observed with percentage of: 8.5%</div>"         ]       ] [
fhir:title [ fhir:v "Result With Treatment--Derived" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ;
fhir:display [ fhir:v "Result with intervention alone (calculated)" ]           ] ) ;
fhir:text [ fhir:v "calculated value derived from the control group and effect estimate" ]         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">6.2%</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104397" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: Myocardial infarction or stroke without bariatric surgery (Control Group) in Swedish Obese Subjects (SOS) study" ]         ] [
fhir:reference [ fhir:v "Evidence/104098" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study" ]         ] )       ] [
fhir:title [ fhir:v "Effect Estimate" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ;
fhir:display [ fhir:v "Result with intervention vs. comparator" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Hazard Ratio 0.67 (95% CI  0.54 to 0.83)</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104098" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study" ]         ] )       ] [
fhir:title [ fhir:v "Certainty of Evidence" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "certainty-of-evidence" ] ;
fhir:display [ fhir:v "Certainty of Evidence" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Low quality</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104098" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study" ]         ] )       ] [
fhir:title [ fhir:v "Assertion" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "assertion" ] ;
fhir:display [ fhir:v "Assertion" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Compared with usual care, bariatric surgery was associated with reduced number of cardiovascular deaths and lower incidence of cardiovascular events in obese adults.</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104098" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study" ]         ] )       ] )     ] [
fhir:title [ fhir:v "Remission of diabetes" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "summary-of-findings-entry-for-a-single-outcome" ] ;
fhir:display [ fhir:v "Summary of findings entry for a single outcome" ]         ] )       ] ;
fhir:focus [
fhir:reference [ fhir:v "EvidenceVariable/104117" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: Remission of diabetes" ]       ] ;
fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"       ] ;
      ( fhir:section [
fhir:title [ fhir:v "Outcome" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "outcome-measure" ] ;
fhir:display [ fhir:v "Outcome Measure" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Remission of diabetes</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "EvidenceVariable/104117" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: Remission of diabetes" ]         ] )       ] [
fhir:title [ fhir:v "Sample Size" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "sample-size" ] ;
fhir:display [ fhir:v "Sample Size" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">1 study, 1,888 participants, 1,888 counted</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104121" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Result Without Treatment" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-comparator-alone" ] ;
fhir:display [ fhir:v "Result with comparator alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">141 out of 956 observed with percentage of: 14.8%</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104396" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: Remission of diabetes without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Result With Treatment--Observed" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone" ] ;
fhir:display [ fhir:v "Result with intervention alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">536 out of 932 observed with percentage of: 57.5%</div>"         ]       ] [
fhir:title [ fhir:v "Result With Treatment--Derived" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ;
fhir:display [ fhir:v "Result with intervention alone (calculated)" ]           ] ) ;
fhir:text [ fhir:v "calculated value derived from the control group and effect estimate" ]         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">57.7%</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104396" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: Remission of diabetes without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study" ]         ] [
fhir:reference [ fhir:v "Evidence/104121" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Effect Estimate" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ;
fhir:display [ fhir:v "Result with intervention vs. comparator" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Relative Risk 3.9 (95% CI  2.8 to 5.4)</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104121" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Certainty of Evidence" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "certainty-of-evidence" ] ;
fhir:display [ fhir:v "Certainty of Evidence" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Moderate quality</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104121" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Assertion" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "assertion" ] ;
fhir:display [ fhir:v "Assertion" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Compared with specialized medical treatment, bariatric surgery appears to induce remission of diabetes.</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104121" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study" ]         ] )       ] )     ] [
fhir:title [ fhir:v "New onset depression" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "summary-of-findings-entry-for-a-single-outcome" ] ;
fhir:display [ fhir:v "Summary of findings entry for a single outcome" ]         ] )       ] ;
fhir:focus [
fhir:reference [ fhir:v "EvidenceVariable/104118" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: New onset depression" ]       ] ;
fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"       ] ;
      ( fhir:section [
fhir:title [ fhir:v "Outcome" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "outcome-measure" ] ;
fhir:display [ fhir:v "Outcome Measure" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">New onset depression</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "EvidenceVariable/104118" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: New onset depression" ]         ] )       ] [
fhir:title [ fhir:v "Sample Size" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "sample-size" ] ;
fhir:display [ fhir:v "Sample Size" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">1 study, 1,888 participants, 1,888 counted</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104155" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Result Without Treatment" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-comparator-alone" ] ;
fhir:display [ fhir:v "Result with comparator alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">62 out of 956 observed with percentage of: 6.5%</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104395" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: New onset depression without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Result With Treatment--Observed" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone" ] ;
fhir:display [ fhir:v "Result with intervention alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">83 out of 932 observed with percentage of: 8.9%</div>"         ]       ] [
fhir:title [ fhir:v "Result With Treatment--Derived" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ;
fhir:display [ fhir:v "Result with intervention alone (calculated)" ]           ] ) ;
fhir:text [ fhir:v "calculated value derived from the control group and effect estimate" ]         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">9.75%</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104395" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: New onset depression without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study" ]         ] [
fhir:reference [ fhir:v "Evidence/104155" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Effect Estimate" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ;
fhir:display [ fhir:v "Result with intervention vs. comparator" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Relative Risk 1.5 (95% CI 1.4 to 1.7)</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104155" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Certainty of Evidence" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "certainty-of-evidence" ] ;
fhir:display [ fhir:v "Certainty of Evidence" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Low quality</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104155" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Assertion" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "assertion" ] ;
fhir:display [ fhir:v "Assertion" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Compared with specialized medical treatment, bariatric surgery may slightly increase the incidence of depression.</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104155" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study" ]         ] )       ] )     ] [
fhir:title [ fhir:v "Treatment with opioids" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "summary-of-findings-entry-for-a-single-outcome" ] ;
fhir:display [ fhir:v "Summary of findings entry for a single outcome" ]         ] )       ] ;
fhir:focus [
fhir:reference [ fhir:v "EvidenceVariable/104119" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: Treatment with opioids" ]       ] ;
fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"       ] ;
      ( fhir:section [
fhir:title [ fhir:v "Outcome" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "outcome-measure" ] ;
fhir:display [ fhir:v "Outcome Measure" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Treatment with opioids</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "EvidenceVariable/104119" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: Treatment with opioids" ]         ] )       ] [
fhir:title [ fhir:v "Sample Size" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "sample-size" ] ;
fhir:display [ fhir:v "Sample Size" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">1 study, 1,888 participants, 1,888 counted</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104156" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Result Without Treatment" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-comparator-alone" ] ;
fhir:display [ fhir:v "Result with comparator alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">151 out of 956 observed with percentage of: 15.8%</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104394" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: Treatment with opioids without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Result With Treatment--Observed" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone" ] ;
fhir:display [ fhir:v "Result with intervention alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">181 out of 932 observed with percentage of: 19.4%</div>"         ]       ] [
fhir:title [ fhir:v "Result With Treatment--Derived" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ;
fhir:display [ fhir:v "Result with intervention alone (calculated)" ]           ] ) ;
fhir:text [ fhir:v "calculated value derived from the control group and effect estimate" ]         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">20.5%</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104394" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: Treatment with opioids without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study" ]         ] [
fhir:reference [ fhir:v "Evidence/104156" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Effect Estimate" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ;
fhir:display [ fhir:v "Result with intervention vs. comparator" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Relative Risk 1.3 (95% CI 1.2 to 1.4)</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104156" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Certainty of Evidence" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "certainty-of-evidence" ] ;
fhir:display [ fhir:v "Certainty of Evidence" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Low quality</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104156" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Assertion" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "assertion" ] ;
fhir:display [ fhir:v "Assertion" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Compared with specialized medical treatment, bariatric surgery may slightly increase the use of opioids.</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104156" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study" ]         ] )       ] )     ] [
fhir:title [ fhir:v "Additional GI surgical procedure" ] ;
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "summary-of-findings-entry-for-a-single-outcome" ] ;
fhir:display [ fhir:v "Summary of findings entry for a single outcome" ]         ] )       ] ;
fhir:focus [
fhir:reference [ fhir:v "EvidenceVariable/104120" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: Additional GI surgical procedure" ]       ] ;
fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"       ] ;
      ( fhir:section [
fhir:title [ fhir:v "Outcome" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "outcome-measure" ] ;
fhir:display [ fhir:v "Outcome Measure" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Additional GI surgical procedure</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "EvidenceVariable/104120" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: Additional GI surgical procedure" ]         ] )       ] [
fhir:title [ fhir:v "Sample Size" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "sample-size" ] ;
fhir:display [ fhir:v "Sample Size" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">1 study, 1,888 participants, 1,888 counted</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104157" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "StudyOutcomeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Result Without Treatment" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-comparator-alone" ] ;
fhir:display [ fhir:v "Result with comparator alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">148 out of 956 observed with percentage of: 15.5%</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104385" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: Additional GI surgical procedure without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Result With Treatment--Observed" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone" ] ;
fhir:display [ fhir:v "Result with intervention alone" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "additional" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">292 out of 932 observed with percentage of: 31.3%</div>"         ]       ] [
fhir:title [ fhir:v "Result With Treatment--Derived" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ;
fhir:display [ fhir:v "Result with intervention alone (calculated)" ]           ] ) ;
fhir:text [ fhir:v "calculated value derived from the control group and effect estimate" ]         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">31%</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104385" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparatorOnlyEvidence: Additional GI surgical procedure without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study" ]         ] [
fhir:reference [ fhir:v "Evidence/104157" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Effect Estimate" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ;
fhir:display [ fhir:v "Result with intervention vs. comparator" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Relative Risk 2.0 (95% CI 1.7 to 2.4)</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104157" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Certainty of Evidence" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "certainty-of-evidence" ] ;
fhir:display [ fhir:v "Certainty of Evidence" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Moderate quality</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104157" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study" ]         ] )       ] [
fhir:title [ fhir:v "Assertion" ] ;
fhir:code [
          ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "assertion" ] ;
fhir:display [ fhir:v "Assertion" ]           ] )         ] ;
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Compared with specialized medical treatment, bariatric surgery appears to increase the rate of additional gastrointestinal surgical procedures.</div>"         ] ;
        ( fhir:entry [
fhir:reference [ fhir:v "Evidence/104157" ] ;
fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ;
fhir:display [ fhir:v "ComparativeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study" ]         ] )       ] )     ] )
  ] ) . #