Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
{
"resourceType" : "Composition",
"id" : "104215",
"meta" : {
"versionId" : "32",
"lastUpdated" : "2024-10-31T14:34:35.665Z",
"profile" : [
🔗 "http://hl7.org/fhir/uv/ebm/StructureDefinition/summary-of-findings"
]
},
"text" : {
"status" : "empty",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"
},
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/artifact-description",
"valueMarkdown" : "Example of SummaryOfFindings Profile of Composition Resource."
},
{
"url" : "http://hl7.org/fhir/StructureDefinition/artifact-copyright",
"valueMarkdown" : "https://creativecommons.org/licenses/by-nc-sa/4.0/"
}
],
"url" : "https://fevir.net/resources/Composition/104215",
"identifier" : [
{
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
"code" : "ACSN",
"display" : "Accession ID"
}
],
"text" : "FEvIR Object Identifier"
},
"system" : "urn:ietf:rfc:3986",
"value" : "https://fevir.net/FOI/104215",
"assigner" : {
"display" : "Computable Publishing LLC"
}
}
],
"status" : "final",
"type" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "SummaryOfFindings",
"display" : "SummaryOfFindings"
}
],
"text" : "Summary of Findings"
},
"subject" : [
{
🔗 "reference" : "Group/179562",
"type" : "Group",
"display" : "EvidenceReportSubject: Clinical Outcomes for Effects of Bariatric Surgery"
}
],
"date" : "2024-10-31T14:34:35.665Z",
"author" : [
{
"type" : "Practitioner",
"display" : "Brian S. Alper"
}
],
"title" : "SummaryOfFindings: Bariatric Surgery Summary of Findings Example for GIN 2022",
"custodian" : {
"display" : "Computable Publishing LLC"
},
"relatesTo" : [
{
"type" : "cite-as",
"label" : "Cite as",
"citation" : "SummaryOfFindings: Bariatric Surgery Summary of Findings Example for GIN 2022 [Database Entry: FHIR Composition Resource]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 104215. Revised 2024-08-07. Available at: https://fevir.net/resources/Composition/104215. Computable resource at: https://fevir.net/FLI/DocumentForComposition104215."
}
],
"section" : [
{
"title" : "Column Headers",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "column-headers",
"display" : "Column Headers"
}
]
},
"entry" : [
{
🔗 "reference" : "Composition/104213",
"type" : "Composition",
"display" : "EvidenceMap: Bariatric Surgery Summary of Findings Example for GIN 2022"
}
],
"section" : [
{
"title" : "Outcome",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "outcome-measure",
"display" : "Outcome Measure"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Outcome</div>"
}
},
{
"title" : "Sample Size",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "sample-size",
"display" : "Sample Size"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Sample size: # studies, # participants, # counted, # events</div>"
}
},
{
"title" : "Result Without Treatment",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-comparator-alone",
"display" : "Result with comparator alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Result without bariatric surgery</div>"
}
},
{
"title" : "Result With Treatment--Observed",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone",
"display" : "Result with intervention alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Result with bariatric surgery</div>"
}
},
{
"title" : "Result With Treatment--Derived",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone-calculated",
"display" : "Result with intervention alone (calculated)"
}
],
"text" : "calculated value derived from the control group and effect estimate"
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Result with bariatric surgery (calculated)</div>"
}
},
{
"title" : "Effect Estimate",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-vs-comparator",
"display" : "Result with intervention vs. comparator"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Effect Estimate (Relative effect)</div>"
}
},
{
"title" : "Certainty of Evidence",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "certainty-of-evidence",
"display" : "Certainty of Evidence"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Certainty of finding (Quality of evidence)</div>"
}
},
{
"title" : "Assertion",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "assertion",
"display" : "Assertion"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">What this means</div>"
}
}
]
},
{
"title" : "Summary of Findings",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "summary-of-findings",
"display" : "Summary of Findings"
}
]
},
"emptyReason" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/list-empty-reason",
"code" : "notstarted",
"display" : "Not Started"
}
]
},
"section" : [
{
"title" : "All-cause mortality",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "summary-of-findings-entry-for-a-single-outcome",
"display" : "Summary of findings entry for a single outcome"
}
]
},
"focus" : {
🔗 "reference" : "EvidenceVariable/49217",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: All-cause mortality"
},
"text" : {
"status" : "empty",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"
},
"section" : [
{
"title" : "Outcome",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "outcome-measure",
"display" : "Outcome Measure"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">All-cause mortality</div>"
},
"entry" : [
{
🔗 "reference" : "EvidenceVariable/49217",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: All-cause mortality"
}
]
},
{
"title" : "Sample Size",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "sample-size",
"display" : "Sample Size"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">21 studies, 397002 participants</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/49328",
"type" : "Evidence",
"display" : "ComparativeEvidence: All-cause mortality effect of bariatric surgery in 2022 meta-analysis"
}
]
},
{
"title" : "Result Without Treatment",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-comparator-alone",
"display" : "Result with comparator alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">5% (estimated); specific summary evidence not reported</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104384",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: All-cause mortality without bariatric surgery in 2022 meta-analysis"
}
]
},
{
"title" : "Result With Treatment--Observed",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone",
"display" : "Result with intervention alone"
}
]
},
"text" : {
"status" : "empty",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Not reported</div>"
}
},
{
"title" : "Result With Treatment--Derived",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone-calculated",
"display" : "Result with intervention alone (calculated)"
}
],
"text" : "calculated value derived from the control group and effect estimate"
},
"text" : {
"status" : "empty",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Not reported</div>"
}
},
{
"title" : "Effect Estimate",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-vs-comparator",
"display" : "Result with intervention vs. comparator"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Hazard Ratio 0.55 (95% confidence interval 0.49 to 0.62)</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/49328",
"type" : "Evidence",
"display" : "ComparativeEvidence: All-cause mortality effect of bariatric surgery in 2022 meta-analysis"
}
]
},
{
"title" : "Certainty of Evidence",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "certainty-of-evidence",
"display" : "Certainty of Evidence"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Low quality</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/49328",
"type" : "Evidence",
"display" : "ComparativeEvidence: All-cause mortality effect of bariatric surgery in 2022 meta-analysis"
}
]
},
{
"title" : "Assertion",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "assertion",
"display" : "Assertion"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">The present systematic review and meta-analysis suggests that bariatric surgery is associated with reduced all-cause and CV mortality.</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/49328",
"type" : "Evidence",
"display" : "ComparativeEvidence: All-cause mortality effect of bariatric surgery in 2022 meta-analysis"
}
]
}
]
},
{
"title" : "Nonfatal myocardial infarction or stroke",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "summary-of-findings-entry-for-a-single-outcome",
"display" : "Summary of findings entry for a single outcome"
}
]
},
"focus" : {
🔗 "reference" : "EvidenceVariable/104097",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: Nonfatal myocardial infarction or stroke"
},
"text" : {
"status" : "empty",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"
},
"section" : [
{
"title" : "Outcome",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "outcome-measure",
"display" : "Outcome Measure"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Nonfatal myocardial infarction or stroke</div>"
},
"entry" : [
{
🔗 "reference" : "EvidenceVariable/104097",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: Nonfatal myocardial infarction or stroke"
}
]
},
{
"title" : "Sample Size",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "sample-size",
"display" : "Sample Size"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">1 study, 4,047 participants, 4,047 counted, 359 events</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104098",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study"
}
]
},
{
"title" : "Result Without Treatment",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-comparator-alone",
"display" : "Result with comparator alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">188 out of 2,037 observed with percentage of: 9.2%</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104397",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: Myocardial infarction or stroke without bariatric surgery (Control Group) in Swedish Obese Subjects (SOS) study"
}
]
},
{
"title" : "Result With Treatment--Observed",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone",
"display" : "Result with intervention alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">171 out of 2,010 observed with percentage of: 8.5%</div>"
}
},
{
"title" : "Result With Treatment--Derived",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone-calculated",
"display" : "Result with intervention alone (calculated)"
}
],
"text" : "calculated value derived from the control group and effect estimate"
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">6.2%</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104397",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: Myocardial infarction or stroke without bariatric surgery (Control Group) in Swedish Obese Subjects (SOS) study"
},
{
🔗 "reference" : "Evidence/104098",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study"
}
]
},
{
"title" : "Effect Estimate",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-vs-comparator",
"display" : "Result with intervention vs. comparator"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Hazard Ratio 0.67 (95% CI 0.54 to 0.83)</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104098",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study"
}
]
},
{
"title" : "Certainty of Evidence",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "certainty-of-evidence",
"display" : "Certainty of Evidence"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Low quality</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104098",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study"
}
]
},
{
"title" : "Assertion",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "assertion",
"display" : "Assertion"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Compared with usual care, bariatric surgery was associated with reduced number of cardiovascular deaths and lower incidence of cardiovascular events in obese adults.</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104098",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study"
}
]
}
]
},
{
"title" : "Remission of diabetes",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "summary-of-findings-entry-for-a-single-outcome",
"display" : "Summary of findings entry for a single outcome"
}
]
},
"focus" : {
🔗 "reference" : "EvidenceVariable/104117",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: Remission of diabetes"
},
"text" : {
"status" : "empty",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"
},
"section" : [
{
"title" : "Outcome",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "outcome-measure",
"display" : "Outcome Measure"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Remission of diabetes</div>"
},
"entry" : [
{
🔗 "reference" : "EvidenceVariable/104117",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: Remission of diabetes"
}
]
},
{
"title" : "Sample Size",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "sample-size",
"display" : "Sample Size"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">1 study, 1,888 participants, 1,888 counted</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104121",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Result Without Treatment",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-comparator-alone",
"display" : "Result with comparator alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">141 out of 956 observed with percentage of: 14.8%</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104396",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: Remission of diabetes without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Result With Treatment--Observed",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone",
"display" : "Result with intervention alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">536 out of 932 observed with percentage of: 57.5%</div>"
}
},
{
"title" : "Result With Treatment--Derived",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone-calculated",
"display" : "Result with intervention alone (calculated)"
}
],
"text" : "calculated value derived from the control group and effect estimate"
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">57.7%</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104396",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: Remission of diabetes without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study"
},
{
🔗 "reference" : "Evidence/104121",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Effect Estimate",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-vs-comparator",
"display" : "Result with intervention vs. comparator"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Relative Risk 3.9 (95% CI 2.8 to 5.4)</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104121",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Certainty of Evidence",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "certainty-of-evidence",
"display" : "Certainty of Evidence"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Moderate quality</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104121",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Assertion",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "assertion",
"display" : "Assertion"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Compared with specialized medical treatment, bariatric surgery appears to induce remission of diabetes.</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104121",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study"
}
]
}
]
},
{
"title" : "New onset depression",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "summary-of-findings-entry-for-a-single-outcome",
"display" : "Summary of findings entry for a single outcome"
}
]
},
"focus" : {
🔗 "reference" : "EvidenceVariable/104118",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: New onset depression"
},
"text" : {
"status" : "empty",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"
},
"section" : [
{
"title" : "Outcome",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "outcome-measure",
"display" : "Outcome Measure"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">New onset depression</div>"
},
"entry" : [
{
🔗 "reference" : "EvidenceVariable/104118",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: New onset depression"
}
]
},
{
"title" : "Sample Size",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "sample-size",
"display" : "Sample Size"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">1 study, 1,888 participants, 1,888 counted</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104155",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Result Without Treatment",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-comparator-alone",
"display" : "Result with comparator alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">62 out of 956 observed with percentage of: 6.5%</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104395",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: New onset depression without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Result With Treatment--Observed",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone",
"display" : "Result with intervention alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">83 out of 932 observed with percentage of: 8.9%</div>"
}
},
{
"title" : "Result With Treatment--Derived",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone-calculated",
"display" : "Result with intervention alone (calculated)"
}
],
"text" : "calculated value derived from the control group and effect estimate"
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">9.75%</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104395",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: New onset depression without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study"
},
{
🔗 "reference" : "Evidence/104155",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Effect Estimate",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-vs-comparator",
"display" : "Result with intervention vs. comparator"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Relative Risk 1.5 (95% CI 1.4 to 1.7)</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104155",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Certainty of Evidence",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "certainty-of-evidence",
"display" : "Certainty of Evidence"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Low quality</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104155",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Assertion",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "assertion",
"display" : "Assertion"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Compared with specialized medical treatment, bariatric surgery may slightly increase the incidence of depression.</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104155",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study"
}
]
}
]
},
{
"title" : "Treatment with opioids",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "summary-of-findings-entry-for-a-single-outcome",
"display" : "Summary of findings entry for a single outcome"
}
]
},
"focus" : {
🔗 "reference" : "EvidenceVariable/104119",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: Treatment with opioids"
},
"text" : {
"status" : "empty",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"
},
"section" : [
{
"title" : "Outcome",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "outcome-measure",
"display" : "Outcome Measure"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Treatment with opioids</div>"
},
"entry" : [
{
🔗 "reference" : "EvidenceVariable/104119",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: Treatment with opioids"
}
]
},
{
"title" : "Sample Size",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "sample-size",
"display" : "Sample Size"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">1 study, 1,888 participants, 1,888 counted</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104156",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Result Without Treatment",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-comparator-alone",
"display" : "Result with comparator alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">151 out of 956 observed with percentage of: 15.8%</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104394",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: Treatment with opioids without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Result With Treatment--Observed",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone",
"display" : "Result with intervention alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">181 out of 932 observed with percentage of: 19.4%</div>"
}
},
{
"title" : "Result With Treatment--Derived",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone-calculated",
"display" : "Result with intervention alone (calculated)"
}
],
"text" : "calculated value derived from the control group and effect estimate"
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">20.5%</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104394",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: Treatment with opioids without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study"
},
{
🔗 "reference" : "Evidence/104156",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Effect Estimate",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-vs-comparator",
"display" : "Result with intervention vs. comparator"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Relative Risk 1.3 (95% CI 1.2 to 1.4)</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104156",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Certainty of Evidence",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "certainty-of-evidence",
"display" : "Certainty of Evidence"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Low quality</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104156",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Assertion",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "assertion",
"display" : "Assertion"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Compared with specialized medical treatment, bariatric surgery may slightly increase the use of opioids.</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104156",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study"
}
]
}
]
},
{
"title" : "Additional GI surgical procedure",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "summary-of-findings-entry-for-a-single-outcome",
"display" : "Summary of findings entry for a single outcome"
}
]
},
"focus" : {
🔗 "reference" : "EvidenceVariable/104120",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: Additional GI surgical procedure"
},
"text" : {
"status" : "empty",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">[No data.]</div>"
},
"section" : [
{
"title" : "Outcome",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "outcome-measure",
"display" : "Outcome Measure"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Additional GI surgical procedure</div>"
},
"entry" : [
{
🔗 "reference" : "EvidenceVariable/104120",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: Additional GI surgical procedure"
}
]
},
{
"title" : "Sample Size",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "sample-size",
"display" : "Sample Size"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">1 study, 1,888 participants, 1,888 counted</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104157",
"type" : "Evidence",
"display" : "StudyOutcomeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Result Without Treatment",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-comparator-alone",
"display" : "Result with comparator alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">148 out of 956 observed with percentage of: 15.5%</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104385",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: Additional GI surgical procedure without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Result With Treatment--Observed",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone",
"display" : "Result with intervention alone"
}
]
},
"text" : {
"status" : "additional",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">292 out of 932 observed with percentage of: 31.3%</div>"
}
},
{
"title" : "Result With Treatment--Derived",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-alone-calculated",
"display" : "Result with intervention alone (calculated)"
}
],
"text" : "calculated value derived from the control group and effect estimate"
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">31%</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104385",
"type" : "Evidence",
"display" : "ComparatorOnlyEvidence: Additional GI surgical procedure without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study"
},
{
🔗 "reference" : "Evidence/104157",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Effect Estimate",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "result-with-intervention-vs-comparator",
"display" : "Result with intervention vs. comparator"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Relative Risk 2.0 (95% CI 1.7 to 2.4)</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104157",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Certainty of Evidence",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "certainty-of-evidence",
"display" : "Certainty of Evidence"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Moderate quality</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104157",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study"
}
]
},
{
"title" : "Assertion",
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "assertion",
"display" : "Assertion"
}
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">Compared with specialized medical treatment, bariatric surgery appears to increase the rate of additional gastrointestinal surgical procedures.</div>"
},
"entry" : [
{
🔗 "reference" : "Evidence/104157",
"type" : "Evidence",
"display" : "ComparativeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study"
}
]
}
]
}
]
}
]
}
IG © 2024+ HL7 International / Clinical Decision Support. Package hl7.fhir.uv.ebm#2.0.0-ballot based on FHIR 6.0.0-ballot2. Generated 2024-11-21
Links: Table of Contents |
QA Report
| Version History |
|
Propose a change