Clinical Genomics Resource Incubator
0.1.0-ci-build - CI Build International flag

Clinical Genomics Resource Incubator, published by HL7 International / Clinical Genomics. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/cg-incubator/ and changes regularly. See the Directory of published versions

CodeSystem: Molecular Definition Type CodeSystem (Experimental)

Official URL: http://hl7.org/fhir/uv/cg-incubator/CodeSystem/moleculardefinition-type Version: 0.1.0-ci-build
Standards status: Informative Draft as of 2026-03-23 Maturity Level: 0 Computable Name: MolecularDefinitionType
Other Identifiers: OID:2.16.840.1.113883.4.642.4.3002

Domain-semantic subtype classifications for a MolecularDefinition resource instance, providing greater specificity than the moleculeType element. For example, an instance with moleculeType 'rna' may have a type of 'mrna' or 'mirna'. This CodeSystem is an enumerated, curated set covering clinically relevant DNA and RNA subtypes. The binding on this CodeSystem is extensible: implementers may use codes from other systems when no suitable code exists here.

This Code system is referenced in the definition of the following value sets:

Last updated: 2026-03-23 00:00:00+0000

Profile: Shareable CodeSystem

This case-sensitive code system http://hl7.org/fhir/uv/cg-incubator/CodeSystem/moleculardefinition-type defines the following codes:

CodeDisplayDefinition
genomic-dna Genomic DNA DNA that encodes, or is derived from, the genomic DNA of an organism.
cdna cDNA A DNA molecule synthesized from a mature mRNA template by reverse transcriptase.
single-stranded-cdna Single-stranded cDNA A cDNA molecule that is single-stranded.
double-stranded-cdna Double-stranded cDNA A cDNA molecule that is double-stranded.
mitochondrial-dna Mitochondrial DNA A DNA sequence of mitochondrial origin.
mrna mRNA Messenger RNA; a mature transcript that is translated into protein.
rrna rRNA Ribosomal RNA; a structural component of the ribosome.
trna tRNA Transfer RNA; an adaptor molecule for translation.
snrna snRNA Small nuclear RNA; involved in pre-mRNA splicing.
snorna snoRNA Small nucleolar RNA; involved in rRNA modification.
mirna miRNA MicroRNA; a small regulatory RNA that silences gene expression.
sirna siRNA Small interfering RNA; mediates RNA interference.
lncrna lncRNA Long non-coding RNA; an ncRNA of 200 nucleotides or more with regulatory roles.
antisense-rna Antisense RNA RNA transcribed from the antisense strand of a gene.
ncrna ncRNA Non-coding RNA; a mature transcript that is not translated into protein.
pirna piRNA PIWI-interacting RNA; involved in transposon silencing in germline cells.

Description of the above table(s).