Clinical Genomics Resource Incubator
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Clinical Genomics Resource Incubator, published by HL7 International / Clinical Genomics. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/cg-incubator/ and changes regularly. See the Directory of published versions

CodeSystem: Molecular Definition Strand CodeSystem (Experimental)

Official URL: http://hl7.org/fhir/uv/cg-incubator/CodeSystem/moleculardefinition-strand Version: 0.1.0-ci-build
Standards status: Informative Draft as of 2026-03-23 Maturity Level: 0 Computable Name: MolecularDefinitionStrand
Other Identifiers: OID:2.16.840.1.113883.4.642.4.3006

The strand orientation of a sequenceLocation. Orientation of molecular sequences, indicating directionality for nucleotides (5' to 3' or 3' to 5') or amino acids (N to C terminus).

This Code system is referenced in the definition of the following value sets:

Last updated: 2026-03-23 00:00:00+0000

Profile: Shareable CodeSystem

This case-sensitive code system http://hl7.org/fhir/uv/cg-incubator/CodeSystem/moleculardefinition-strand defines the following codes:

CodeDisplayDefinition
forward Forward strand 5' to 3' for nucleotides or N-to-C for amino acids; also known as the positive/plus/sense/Watson strand. Single stranded sequences are conventionally represented in the forward direction.
reverse Reverse strand 3' to 5' orientation; also known as the negative/minus/antisense/Crick strand. Applicable only to double stranded sequences.

Description of the above table(s).