Clinical Genomics Resource Incubator
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Clinical Genomics Resource Incubator, published by HL7 International / Clinical Genomics. This guide is not an authorized publication; it is the continuous build for version 0.1.0-ci-build built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/cg-incubator/ and changes regularly. See the Directory of published versions

ValueSet: Molecular Definition Strand (Experimental)

Official URL: http://hl7.org/fhir/uv/cg-incubator/ValueSet/moleculardefinition-strand Version: 0.1.0-ci-build
Standards status: Informative Draft as of 2026-03-13 Maturity Level: 0 Computable Name: MolecularDefinitionStrand
Other Identifiers: OID:2.16.840.1.113883.4.642.3.3006

The strand orientation of a sequenceLocation. 'Forward' corresponds to the plus/sense/Watson strand (5' to 3' in the standard reference orientation); 'reverse' corresponds to the minus/antisense/Crick strand (3' to 5' in the standard reference orientation).

References

Logical Definition (CLD)

Last updated: 2026-03-13 00:00:00+0000

Profile: Shareable ValueSet

 

Expansion

Expansion performed internally based on codesystem Molecular Definition Strand CodeSystem v0.1.0-ci-build (CodeSystem)

This value set contains 2 concepts

SystemCodeDisplay (en)DefinitionJSONXML
http://hl7.org/fhir/uv/cg-incubator/CodeSystem/moleculardefinition-strand  forwardForward strand5' to 3' for nucleotides or N-to-C for amino acids; also known as the positive/plus/sense/Watson strand. Single stranded sequences are conventionally represented in the forward direction.
http://hl7.org/fhir/uv/cg-incubator/CodeSystem/moleculardefinition-strand  reverseReverse strand3' to 5' orientation; also known as the negative/minus/antisense/Crick strand. Applicable only to double stranded sequences.

Description of the above table(s).