Mixture substance: D&C Yellow No. 10 Aluminum Lake — pharmaceutical colorant excipient (data from FDA GSRS). Components are inlined as contained resources for example convenience; real-world mixtures would typically reference standalone SubstanceDefinition resources by URL. (id = "dc-yellow-10-al-lake")

<?xml version="1.0" encoding="UTF-8"?>

<!--  Example: D&C Yellow No. 10 Aluminum Lake — a pharmaceutical colorant
     used as an excipient in tablet coatings. A real mixture substance from
     GSRS (FDA Global Substance Registration System; UNII CQ3XH3DET6,
     UUID 820db676-383b-4c64-b693-671cd181a136).

     Demonstrates one way to model a substance mixture in FHIR
     SubstanceDefinition. The mixture references its component substances via
     .relationship with type=Component. In real-world use the components
     would typically be standalone SubstanceDefinition resources referenced
     by URL; here they are inlined as contained resources purely for example
     convenience, so the file is self-contained.  --><SubstanceDefinition xmlns="http://hl7.org/fhir">
  <id value="dc-yellow-10-al-lake"/> 
  <contained> 
    <SubstanceDefinition> 
      <id value="comp-quinoline-6-sulfonate"/> 
      <classification> 
        <coding> 
          <system value="http://example.europa.eu/fhir/SubstanceType"/> 
          <code value="chemical"/> 
          <display value="Chemical"/> 
        </coding> 
      </classification> 
      <name> 
        <name value="Aluminum 2-(1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinoline-6-sulfonate"/> 
        <preferred value="true"/> 
      </name> 
    </SubstanceDefinition> 
  </contained> 
  <contained> 
    <SubstanceDefinition> 
      <id value="comp-quinoline-8-sulfonate"/> 
      <classification> 
        <coding> 
          <system value="http://example.europa.eu/fhir/SubstanceType"/> 
          <code value="chemical"/> 
          <display value="Chemical"/> 
        </coding> 
      </classification> 
      <name> 
        <name value="Aluminum 2-(1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinoline-8-sulfonate"/> 
        <preferred value="true"/> 
      </name> 
    </SubstanceDefinition> 
  </contained> 
  <contained> 
    <SubstanceDefinition> 
      <id value="comp-substrate"/> 
      <classification> 
        <coding> 
          <system value="http://example.europa.eu/fhir/SubstanceType"/> 
          <code value="chemical"/> 
          <display value="Chemical"/> 
        </coding> 
      </classification> 
      <name> 
        <name value="Unspecified aluminum substrate"/> 
        <preferred value="true"/> 
      </name> 
      <description value="The aluminum substrate onto which the dye is precipitated to form the lake. Unspecified
       in GSRS."/> 
    </SubstanceDefinition> 
  </contained> 
  <identifier> 
    <system value="http://fdasis.nlm.nih.gov"/> 
    <value value="CQ3XH3DET6"/> 
  </identifier> 
  <status> 
    <coding> 
      <system value="http://hl7.org/fhir/publication-status"/> 
      <code value="active"/> 
      <display value="Active"/> 
    </coding> 
  </status> 
  <classification> 
    <coding> 
      <system value="http://example.europa.eu/fhir/SubstanceType"/> 
      <code value="mixture"/> 
      <display value="Mixture"/> 
    </coding> 
  </classification> 
  <domain> 
    <coding> 
      <system value="http://example.europa.eu/fhir/Domain"/> 
      <code value="human"/> 
      <display value="Human use"/> 
    </coding> 
  </domain> 
  <description value="D&amp;C Yellow No. 10 Aluminum Lake — a pharmaceutical colorant produced by precipitating
   D&amp;C Yellow No. 10 (a mixture of the 6- and 8-sulfonate isomers of aluminum
   quinoline-2-yl-indanedione) onto an aluminum substrate. Used as an excipient (colourant)
   in solid oral dosage forms."/> 
  <code> 
    <code> 
      <coding> 
        <system value="http://fdasis.nlm.nih.gov"/> 
        <code value="CQ3XH3DET6"/> 
        <display value="D&amp;C YELLOW NO. 10 ALUMINUM LAKE"/> 
      </coding> 
    </code> 
  </code> 
  <name> 
    <name value="D&amp;C Yellow No. 10 Aluminum Lake"/> 
    <preferred value="true"/> 
    <language> 
      <coding> 
        <system value="urn:ietf:bcp:47"/> 
        <code value="en"/> 
        <display value="English"/> 
      </coding> 
    </language> 
  </name> 
  <relationship> 
    <substanceDefinitionReference> 
      <reference value="#comp-quinoline-6-sulfonate"/> 
      <display value="Aluminum quinoline-6-sulfonate isomer"/> 
    </substanceDefinitionReference> 
    <type> 
      <coding> 
        <system value="http://hl7.org/fhir/substance-relationship-type"/> 
        <code value="Component"/> 
        <display value="Component"/> 
      </coding> 
    </type> 
  </relationship> 
  <relationship> 
    <substanceDefinitionReference> 
      <reference value="#comp-quinoline-8-sulfonate"/> 
      <display value="Aluminum quinoline-8-sulfonate isomer"/> 
    </substanceDefinitionReference> 
    <type> 
      <coding> 
        <system value="http://hl7.org/fhir/substance-relationship-type"/> 
        <code value="Component"/> 
        <display value="Component"/> 
      </coding> 
    </type> 
  </relationship> 
  <relationship> 
    <substanceDefinitionReference> 
      <reference value="#comp-substrate"/> 
      <display value="Unspecified aluminum substrate"/> 
    </substanceDefinitionReference> 
    <type> 
      <coding> 
        <system value="http://hl7.org/fhir/substance-relationship-type"/> 
        <code value="Component"/> 
        <display value="Component"/> 
      </coding> 
    </type> 
  </relationship> 
</SubstanceDefinition>