Mixture substance: D&C Yellow No. 10 Aluminum Lake — pharmaceutical colorant excipient (data from FDA GSRS). Components are inlined as contained resources for example convenience; real-world mixtures would typically reference standalone SubstanceDefinition resources by URL.

{
  "resourceType" : "SubstanceDefinition",
  "id" : "dc-yellow-10-al-lake",
  "contained" : [{
    "resourceType" : "SubstanceDefinition",
    "id" : "comp-quinoline-6-sulfonate",
    "classification" : [{
      "coding" : [{
        "system" : "http://example.europa.eu/fhir/SubstanceType",
        "code" : "chemical",
        "display" : "Chemical"
      }]
    }],
    "name" : [{
      "name" : "Aluminum 2-(1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinoline-6-sulfonate",
      "preferred" : true
    }]
  },
  {
    "resourceType" : "SubstanceDefinition",
    "id" : "comp-quinoline-8-sulfonate",
    "classification" : [{
      "coding" : [{
        "system" : "http://example.europa.eu/fhir/SubstanceType",
        "code" : "chemical",
        "display" : "Chemical"
      }]
    }],
    "name" : [{
      "name" : "Aluminum 2-(1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinoline-8-sulfonate",
      "preferred" : true
    }]
  },
  {
    "resourceType" : "SubstanceDefinition",
    "id" : "comp-substrate",
    "classification" : [{
      "coding" : [{
        "system" : "http://example.europa.eu/fhir/SubstanceType",
        "code" : "chemical",
        "display" : "Chemical"
      }]
    }],
    "name" : [{
      "name" : "Unspecified aluminum substrate",
      "preferred" : true
    }],
    "description" : "The aluminum substrate onto which the dye is precipitated to form the lake. Unspecified in GSRS."
  }],
  "identifier" : [{
    "system" : "http://fdasis.nlm.nih.gov",
    "value" : "CQ3XH3DET6"
  }],
  "status" : {
    "coding" : [{
      "system" : "http://hl7.org/fhir/publication-status",
      "code" : "active",
      "display" : "Active"
    }]
  },
  "classification" : [{
    "coding" : [{
      "system" : "http://example.europa.eu/fhir/SubstanceType",
      "code" : "mixture",
      "display" : "Mixture"
    }]
  }],
  "domain" : {
    "coding" : [{
      "system" : "http://example.europa.eu/fhir/Domain",
      "code" : "human",
      "display" : "Human use"
    }]
  },
  "description" : "D&C Yellow No. 10 Aluminum Lake — a pharmaceutical colorant produced by precipitating D&C Yellow No. 10 (a mixture of the 6- and 8-sulfonate isomers of aluminum quinoline-2-yl-indanedione) onto an aluminum substrate. Used as an excipient (colourant) in solid oral dosage forms.",
  "code" : [{
    "code" : {
      "coding" : [{
        "system" : "http://fdasis.nlm.nih.gov",
        "code" : "CQ3XH3DET6",
        "display" : "D&C YELLOW NO. 10 ALUMINUM LAKE"
      }]
    }
  }],
  "name" : [{
    "name" : "D&C Yellow No. 10 Aluminum Lake",
    "preferred" : true,
    "language" : [{
      "coding" : [{
        "system" : "urn:ietf:bcp:47",
        "code" : "en",
        "display" : "English"
      }]
    }]
  }],
  "relationship" : [{
    "substanceDefinitionReference" : {
      "reference" : "#comp-quinoline-6-sulfonate",
      "display" : "Aluminum quinoline-6-sulfonate isomer"
    },
    "type" : {
      "coding" : [{
        "system" : "http://hl7.org/fhir/substance-relationship-type",
        "code" : "Component",
        "display" : "Component"
      }]
    }
  },
  {
    "substanceDefinitionReference" : {
      "reference" : "#comp-quinoline-8-sulfonate",
      "display" : "Aluminum quinoline-8-sulfonate isomer"
    },
    "type" : {
      "coding" : [{
        "system" : "http://hl7.org/fhir/substance-relationship-type",
        "code" : "Component",
        "display" : "Component"
      }]
    }
  },
  {
    "substanceDefinitionReference" : {
      "reference" : "#comp-substrate",
      "display" : "Unspecified aluminum substrate"
    },
    "type" : {
      "coding" : [{
        "system" : "http://hl7.org/fhir/substance-relationship-type",
        "code" : "Component",
        "display" : "Component"
      }]
    }
  }]
}