Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

Resource Profile: NetEffectEstimate

Official URL: http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-estimate Version: 2.0.0-ballot
Standards status: Draft Maturity Level: 1 Computable Name: NetEffectEstimate
Other Identifiers: OID:2.16.840.1.113883.4.642.40.44.42.64

Profile of Evidence for Evidence Based Medicine IG. The NetEffectEstimate Profile is used for evidence in which the observed data is net effect contributions (effect estimates expressed as risk differences, multiplied by relative importance ratings of outcomes).

See Understanding the Evidence Resource for additional information.

Usage:

Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

This structure is derived from Evidence

NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence 0..* Evidence Single evidence bit
... Slices for variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
Slice: Unordered, Open by value:variableRole
.... variableDefinition:population 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... variableRole 1..1 code population | exposure | outcome | covariate
Required Pattern: population
..... observed 0..1 Reference(NetEffectContributions) Definition of the actual variable related to the statistic(s)
..... intended 0..0
.... variableDefinition:exposure 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... variableRole 1..1 code population | exposure | outcome | covariate
Required Pattern: exposure
..... comparatorCategory 1..1 string The reference value used for comparison
..... observed 0..1 Reference(GroupAssignment) Definition of the actual variable related to the statistic(s)
..... intended 0..0
... Slices for statistic 1..* BackboneElement Values and parameters for a single statistic
Slice: Unordered, Open by value:statisticType.coding
.... statistic:netEffect S 1..1 BackboneElement Values and parameters for a single statistic
..... statisticType
...... coding 1..1 Coding Code defined by a terminology system
Required Pattern: At least the following
....... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
....... code 1..1 code Symbol in syntax defined by the system
Fixed Value: STATO:0000424
....... display 1..1 string Representation defined by the system
Fixed Value: Risk Difference
..... Slices for attributeEstimate 1..* BackboneElement An attribute of the Statistic
Slice: Unordered, Open by value:type.coding
...... attributeEstimate:confidenceInterval S 1..1 BackboneElement An attribute of the Statistic
....... type
........ coding 1..1 Coding Code defined by a terminology system
Required Pattern: At least the following
......... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
......... code 1..1 code Symbol in syntax defined by the system
Fixed Value: STATO:0000196
......... display 1..1 string Representation defined by the system
Fixed Value: confidence interval
..... Slices for modelCharacteristic 1..* BackboneElement An aspect of the statistical model
Slice: Unordered, Open by value:code.coding
...... modelCharacteristic:netEffectAnalysis S 1..1 BackboneElement An aspect of the statistical model
....... code
........ coding 1..1 Coding Code defined by a terminology system
Required Pattern: At least the following
......... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
......... code 1..1 code Symbol in syntax defined by the system
Fixed Value: TBD:net-effect-analysis
......... display 1..1 string Representation defined by the system
Fixed Value: Net effect analysis

doco Documentation for this format
NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence C 0..* Evidence Single evidence bit
cnl-0: Name should be usable as an identifier for the module by machine processing applications such as code generation
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... contained 0..* Resource Contained, inline Resources
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... Slices for variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
Slice: Unordered, Open by value:variableRole
.... variableDefinition:All Slices Content/Rules for all slices
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.

.... variableDefinition:population 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: population
..... observed Σ 0..1 Reference(NetEffectContributions) Definition of the actual variable related to the statistic(s)
.... variableDefinition:exposure 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: exposure
..... comparatorCategory 1..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(GroupAssignment) Definition of the actual variable related to the statistic(s)
... Slices for statistic 1..* BackboneElement Values and parameters for a single statistic
Slice: Unordered, Open by value:statisticType.coding
.... statistic:All Slices Content/Rules for all slices
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... statistic:netEffect S 1..1 BackboneElement Values and parameters for a single statistic
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... Slices for attributeEstimate 1..* BackboneElement An attribute of the Statistic
Slice: Unordered, Open by value:type.coding
...... attributeEstimate:All Slices Content/Rules for all slices
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... attributeEstimate:confidenceInterval S 1..1 BackboneElement An attribute of the Statistic
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... Slices for modelCharacteristic 1..* BackboneElement An aspect of the statistical model
Slice: Unordered, Open by value:code.coding
...... modelCharacteristic:All Slices Content/Rules for all slices
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... code 1..1 CodeableConcept Model specification
Binding: StatisticModelCode (extensible)
...... modelCharacteristic:netEffectAnalysis S 1..1 BackboneElement An aspect of the statistical model
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... code 1..1 CodeableConcept Model specification
Binding: StatisticModelCode (extensible)
........ coding 1..1 Coding Code defined by a terminology system

Required Pattern: At least the following
......... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
......... code 1..1 code Symbol in syntax defined by the system
Fixed Value: TBD:net-effect-analysis
......... display 1..1 string Representation defined by the system
Fixed Value: Net effect analysis

doco Documentation for this format

Terminology Bindings

PathConformanceValueSet / CodeURI
Evidence.statusrequiredPublicationStatus
http://hl7.org/fhir/ValueSet/publication-status|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.variableRolerequiredEvidenceVariableRole
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:population.variableRolerequiredPattern: population
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:exposure.variableRolerequiredPattern: exposure
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic:netEffectAnalysis.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard

Constraints

IdGradePath(s)DetailsRequirements
cnl-0warningEvidenceName should be usable as an identifier for the module by machine processing applications such as code generation
: name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$')
ele-1error**ALL** elementsAll FHIR elements must have a @value or children
: hasValue() or (children().count() > id.count())
NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence C 0..* Evidence Single evidence bit
cnl-0: Name should be usable as an identifier for the module by machine processing applications such as code generation
... id Σ 0..1 id Logical id of this artifact
... meta Σ 0..1 Meta Metadata about the resource
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... language 0..1 code Language of the resource content
Binding: AllLanguages (required): IETF language tag for a human language

Additional BindingsPurpose
CommonLanguages Starter Set
... text 0..1 Narrative Text summary of the resource, for human interpretation
... contained 0..* Resource Contained, inline Resources
... extension 0..* Extension Additional content defined by implementations
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... url ΣC 0..1 uri Canonical identifier for this evidence, represented as a globally unique URI
cnl-1: URL should not contain | or # - these characters make processing canonical references problematic
... identifier Σ 0..* Identifier Additional identifier for the summary
... version Σ 0..1 string Business version of this summary
... versionAlgorithm[x] Σ 0..1 How to compare versions
Binding: VersionAlgorithm (extensible)
.... versionAlgorithmString string
.... versionAlgorithmCoding Coding
... name C 0..1 string Name for this summary (machine friendly)
... title Σ 0..1 string Name for this summary (human friendly)
... citeAs[x] 0..1 Citation for this evidence
.... citeAsReference Reference(Citation)
.... citeAsMarkdown markdown
... status ?!Σ 1..1 code draft | active | retired | unknown
Binding: PublicationStatus (required): The lifecycle status of an artifact.

... experimental 0..1 boolean For testing purposes, not real usage
... date Σ 0..1 dateTime Date last changed
... approvalDate 0..1 date When the summary was approved by publisher
... lastReviewDate 0..1 date When the summary was last reviewed by the publisher
... publisher Σ 0..1 string Name of the publisher/steward (organization or individual)
... contact Σ 0..* ContactDetail Contact details for the publisher
... author Σ 0..* ContactDetail Who authored the content
... editor 0..* ContactDetail Who edited the content
... reviewer 0..* ContactDetail Who reviewed the content
... endorser Σ 0..* ContactDetail Who endorsed the content
... useContext Σ 0..* UsageContext The context that the content is intended to support
... purpose 0..1 markdown Why this Evidence is defined
... copyright 0..1 markdown Use and/or publishing restrictions
... copyrightLabel 0..1 string Copyright holder and year(s)
... relatedArtifact 0..* RelatedArtifact Link or citation to artifact associated with the summary
... description 0..1 markdown Description of the particular summary
... assertion 0..1 markdown Declarative description of the Evidence
... note 0..* Annotation Footnotes and/or explanatory notes
... Slices for variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
Slice: Unordered, Open by value:variableRole
.... variableDefinition:All Slices Content/Rules for all slices
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.

..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 0..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(Group | EvidenceVariable) Definition of the actual variable related to the statistic(s)
..... intended 0..1 Reference(Group | EvidenceVariable) Definition of the intended variable related to the Evidence
..... directnessMatch 0..1 CodeableConcept low | moderate | high | exact
Binding: EvidenceDirectness (extensible): The quality of how direct the match is.

.... variableDefinition:population 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: population
..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 0..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(NetEffectContributions) Definition of the actual variable related to the statistic(s)
..... directnessMatch 0..1 CodeableConcept low | moderate | high | exact
Binding: EvidenceDirectness (extensible): The quality of how direct the match is.

.... variableDefinition:exposure 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: exposure
..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 1..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(GroupAssignment) Definition of the actual variable related to the statistic(s)
..... directnessMatch 0..1 CodeableConcept low | moderate | high | exact
Binding: EvidenceDirectness (extensible): The quality of how direct the match is.

... synthesisType 0..1 CodeableConcept The method to combine studies
Binding: StatisticSynthesisType (extensible): Types of combining results from a body of evidence (e.g. summary data meta-analysis).

... studyDesign 0..* CodeableConcept The design of the study that produced this evidence
Binding: StudyDesign (extensible): This is a set of terms for study design characteristics.


... Slices for statistic 1..* BackboneElement Values and parameters for a single statistic
Slice: Unordered, Open by value:statisticType.coding
.... statistic:All Slices Content/Rules for all slices
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown Description of content
..... note 0..* Annotation Footnotes and/or explanatory notes
..... statisticType 0..1 CodeableConcept Type of statistic, e.g., relative risk
Binding: StatisticType (extensible)
..... category 0..1 CodeableConcept Associated category for categorical variable
..... quantity 0..1 Quantity Statistic value
..... numberOfEvents 0..1 unsignedInt The number of events associated with the statistic
..... numberAffected 0..1 unsignedInt The number of participants affected
..... sampleSize 0..1 BackboneElement Number of samples in the statistic
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... description 0..1 markdown Textual description of sample size for statistic
...... note 0..* Annotation Footnote or explanatory note about the sample size
...... numberOfStudies 0..1 unsignedInt Number of contributing studies
...... numberOfParticipants 0..1 unsignedInt Cumulative number of participants
...... knownDataCount 0..1 unsignedInt Number of participants with known results for measured variables
..... attributeEstimate 0..* BackboneElement An attribute of the Statistic
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... description 0..1 markdown Textual description of the attribute estimate
...... note 0..* Annotation Footnote or explanatory note about the estimate
...... type 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value
Binding: AttributeEstimateType (extensible)
...... quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
...... level 0..1 decimal Level of confidence interval, e.g., 0.95 for 95% confidence interval
...... range 0..1 Range Lower and upper bound values of the attribute estimate
...... attributeEstimate 0..* See attributeEstimate (Evidence) A nested attribute estimate; which is the attribute estimate of an attribute estimate
..... modelCharacteristic 0..* BackboneElement An aspect of the statistical model
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... code 1..1 CodeableConcept Model specification
Binding: StatisticModelCode (extensible)
...... value[x] 0..1 The specific value (when paired with code)
....... valueQuantity Quantity(SimpleQuantity)
....... valueRange Range
....... valueCodeableConcept CodeableConcept
...... intended 0..1 boolean The plan for analysis
...... applied 0..1 boolean The analysis that was applied
...... variable 0..* BackboneElement A variable adjusted for in the adjusted analysis
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... variableDefinition 1..1 Reference(Group | EvidenceVariable) Description of the variable
....... handling 0..1 code continuous | dichotomous | ordinal | polychotomous
Binding: EvidenceVariableHandling (required)
....... valueCategory 0..* CodeableConcept Description for grouping of ordinal or polychotomous variables
....... valueQuantity 0..* Quantity Discrete value for grouping of ordinal or polychotomous variables
....... valueRange 0..* Range Range of values for grouping of ordinal or polychotomous variables
...... attribute 0..* See attributeEstimate (Evidence) An attribute of the statistic used as a model characteristic
.... statistic:netEffect S 1..1 BackboneElement Values and parameters for a single statistic
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown Description of content
..... note 0..* Annotation Footnotes and/or explanatory notes
..... statisticType 0..1 CodeableConcept Type of statistic, e.g., relative risk
Binding: StatisticType (extensible)
...... id 0..1 id Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
...... coding 1..1 Coding Code defined by a terminology system

Required Pattern: At least the following
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
....... version 0..1 string Version of the system - if relevant
....... code 1..1 code Symbol in syntax defined by the system
Fixed Value: STATO:0000424
....... display 1..1 string Representation defined by the system
Fixed Value: Risk Difference
....... userSelected 0..1 boolean If this coding was chosen directly by the user
...... text 0..1 string Plain text representation of the concept
..... category 0..1 CodeableConcept Associated category for categorical variable
..... quantity 0..1 Quantity Statistic value
..... numberOfEvents 0..1 unsignedInt The number of events associated with the statistic
..... numberAffected 0..1 unsignedInt The number of participants affected
..... sampleSize 0..1 BackboneElement Number of samples in the statistic
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... description 0..1 markdown Textual description of sample size for statistic
...... note 0..* Annotation Footnote or explanatory note about the sample size
...... numberOfStudies 0..1 unsignedInt Number of contributing studies
...... numberOfParticipants 0..1 unsignedInt Cumulative number of participants
...... knownDataCount 0..1 unsignedInt Number of participants with known results for measured variables
..... Slices for attributeEstimate 1..* BackboneElement An attribute of the Statistic
Slice: Unordered, Open by value:type.coding
...... attributeEstimate:All Slices Content/Rules for all slices
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... description 0..1 markdown Textual description of the attribute estimate
....... note 0..* Annotation Footnote or explanatory note about the estimate
....... type 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value
Binding: AttributeEstimateType (extensible)
....... quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
....... level 0..1 decimal Level of confidence interval, e.g., 0.95 for 95% confidence interval
....... range 0..1 Range Lower and upper bound values of the attribute estimate
....... attributeEstimate 0..* See attributeEstimate (Evidence) A nested attribute estimate; which is the attribute estimate of an attribute estimate
...... attributeEstimate:confidenceInterval S 1..1 BackboneElement An attribute of the Statistic
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... description 0..1 markdown Textual description of the attribute estimate
....... note 0..* Annotation Footnote or explanatory note about the estimate
....... type 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value
Binding: AttributeEstimateType (extensible)
........ id 0..1 id Unique id for inter-element referencing
........ extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
........ coding 1..1 Coding Code defined by a terminology system

Required Pattern: At least the following
......... id 0..1 string Unique id for inter-element referencing
......... extension 0..* Extension Additional content defined by implementations
......... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
......... version 0..1 string Version of the system - if relevant
......... code 1..1 code Symbol in syntax defined by the system
Fixed Value: STATO:0000196
......... display 1..1 string Representation defined by the system
Fixed Value: confidence interval
......... userSelected 0..1 boolean If this coding was chosen directly by the user
........ text 0..1 string Plain text representation of the concept
....... quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
....... level 0..1 decimal Level of confidence interval, e.g., 0.95 for 95% confidence interval
....... range 0..1 Range Lower and upper bound values of the attribute estimate
....... attributeEstimate 0..* See attributeEstimate (Evidence) A nested attribute estimate; which is the attribute estimate of an attribute estimate
..... Slices for modelCharacteristic 1..* BackboneElement An aspect of the statistical model
Slice: Unordered, Open by value:code.coding
...... modelCharacteristic:All Slices Content/Rules for all slices
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... code 1..1 CodeableConcept Model specification
Binding: StatisticModelCode (extensible)
....... value[x] 0..1 The specific value (when paired with code)
........ valueQuantity Quantity(SimpleQuantity)
........ valueRange Range
........ valueCodeableConcept CodeableConcept
....... intended 0..1 boolean The plan for analysis
....... applied 0..1 boolean The analysis that was applied
....... variable 0..* BackboneElement A variable adjusted for in the adjusted analysis
........ id 0..1 string Unique id for inter-element referencing
........ extension 0..* Extension Additional content defined by implementations
........ modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
........ variableDefinition 1..1 Reference(Group | EvidenceVariable) Description of the variable
........ handling 0..1 code continuous | dichotomous | ordinal | polychotomous
Binding: EvidenceVariableHandling (required)
........ valueCategory 0..* CodeableConcept Description for grouping of ordinal or polychotomous variables
........ valueQuantity 0..* Quantity Discrete value for grouping of ordinal or polychotomous variables
........ valueRange 0..* Range Range of values for grouping of ordinal or polychotomous variables
....... attribute 0..* See attributeEstimate (Evidence) An attribute of the statistic used as a model characteristic
...... modelCharacteristic:netEffectAnalysis S 1..1 BackboneElement An aspect of the statistical model
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... code 1..1 CodeableConcept Model specification
Binding: StatisticModelCode (extensible)
........ id 0..1 id Unique id for inter-element referencing
........ extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
........ coding 1..1 Coding Code defined by a terminology system

Required Pattern: At least the following
......... id 0..1 string Unique id for inter-element referencing
......... extension 0..* Extension Additional content defined by implementations
......... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
......... version 0..1 string Version of the system - if relevant
......... code 1..1 code Symbol in syntax defined by the system
Fixed Value: TBD:net-effect-analysis
......... display 1..1 string Representation defined by the system
Fixed Value: Net effect analysis
......... userSelected 0..1 boolean If this coding was chosen directly by the user
........ text 0..1 string Plain text representation of the concept
....... value[x] 0..1 The specific value (when paired with code)
........ valueQuantity Quantity(SimpleQuantity)
........ valueRange Range
........ valueCodeableConcept CodeableConcept
....... intended 0..1 boolean The plan for analysis
....... applied 0..1 boolean The analysis that was applied
....... variable 0..* BackboneElement A variable adjusted for in the adjusted analysis
........ id 0..1 string Unique id for inter-element referencing
........ extension 0..* Extension Additional content defined by implementations
........ modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
........ variableDefinition 1..1 Reference(Group | EvidenceVariable) Description of the variable
........ handling 0..1 code continuous | dichotomous | ordinal | polychotomous
Binding: EvidenceVariableHandling (required)
........ valueCategory 0..* CodeableConcept Description for grouping of ordinal or polychotomous variables
........ valueQuantity 0..* Quantity Discrete value for grouping of ordinal or polychotomous variables
........ valueRange 0..* Range Range of values for grouping of ordinal or polychotomous variables
....... attribute 0..* See attributeEstimate (Evidence) An attribute of the statistic used as a model characteristic
... certainty 0..* BackboneElement Certainty or quality of the evidence
.... id 0..1 string Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
.... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... description 0..1 markdown Textual description of certainty
.... note 0..* Annotation Footnotes and/or explanatory notes
.... type 0..1 CodeableConcept Aspect of certainty being rated
Binding: EvidenceCertaintyType (extensible): The aspect of quality, confidence, or certainty.

.... rating 0..1 CodeableConcept Assessment or judgement of the aspect
Binding: EvidenceCertaintyRating (extensible): The assessment of quality, confidence, or certainty.

.... rater 0..1 string Individual or group who did the rating
.... subcomponent 0..* See certainty (Evidence) A domain or subdomain of certainty

doco Documentation for this format

Terminology Bindings

PathConformanceValueSet / CodeURI
Evidence.languagerequiredAllLanguages
http://hl7.org/fhir/ValueSet/all-languages|6.0.0-ballot2
from the FHIR Standard
Evidence.versionAlgorithm[x]extensibleVersionAlgorithm
http://hl7.org/fhir/ValueSet/version-algorithm
from the FHIR Standard
Evidence.statusrequiredPublicationStatus
http://hl7.org/fhir/ValueSet/publication-status|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.variableRolerequiredEvidenceVariableRole
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.variableDefinition.directnessMatchextensibleEvidenceDirectness
http://terminology.hl7.org/ValueSet/directness
Evidence.variableDefinition:population.variableRolerequiredPattern: population
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:population.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.variableDefinition:population.directnessMatchextensibleEvidenceDirectness
http://terminology.hl7.org/ValueSet/directness
Evidence.variableDefinition:exposure.variableRolerequiredPattern: exposure
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:exposure.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.variableDefinition:exposure.directnessMatchextensibleEvidenceDirectness
http://terminology.hl7.org/ValueSet/directness
Evidence.synthesisTypeextensibleStatisticSynthesisType
http://terminology.hl7.org/ValueSet/synthesis-type
Evidence.studyDesignextensibleStudyDesign
http://hl7.org/fhir/ValueSet/study-design
from the FHIR Standard
Evidence.statistic.statisticTypeextensibleStatisticType
http://hl7.org/fhir/ValueSet/statistic-type
from the FHIR Standard
Evidence.statistic.attributeEstimate.typeextensibleAttributeEstimateType
http://hl7.org/fhir/ValueSet/attribute-estimate-type
from the FHIR Standard
Evidence.statistic.modelCharacteristic.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard
Evidence.statistic.modelCharacteristic.variable.handlingrequiredEvidenceVariableHandling
http://hl7.org/fhir/ValueSet/variable-handling|6.0.0-ballot2
from the FHIR Standard
Evidence.statistic:netEffect.statisticTypeextensibleStatisticType
http://hl7.org/fhir/ValueSet/statistic-type
from the FHIR Standard
Evidence.statistic:netEffect.attributeEstimate.typeextensibleAttributeEstimateType
http://hl7.org/fhir/ValueSet/attribute-estimate-type
from the FHIR Standard
Evidence.statistic:netEffect.attributeEstimate:confidenceInterval.typeextensibleAttributeEstimateType
http://hl7.org/fhir/ValueSet/attribute-estimate-type
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic.variable.handlingrequiredEvidenceVariableHandling
http://hl7.org/fhir/ValueSet/variable-handling|6.0.0-ballot2
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic:netEffectAnalysis.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic:netEffectAnalysis.variable.handlingrequiredEvidenceVariableHandling
http://hl7.org/fhir/ValueSet/variable-handling|6.0.0-ballot2
from the FHIR Standard
Evidence.certainty.typeextensibleEvidenceCertaintyType
http://hl7.org/fhir/ValueSet/certainty-type
from the FHIR Standard
Evidence.certainty.ratingextensibleEvidenceCertaintyRating
http://hl7.org/fhir/ValueSet/certainty-rating
from the FHIR Standard

Constraints

IdGradePath(s)DetailsRequirements
cnl-0warningEvidenceName should be usable as an identifier for the module by machine processing applications such as code generation
: name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$')
cnl-1warningEvidence.urlURL should not contain | or # - these characters make processing canonical references problematic
: exists() implies matches('^[^|# ]+$')
ele-1error**ALL** elementsAll FHIR elements must have a @value or children
: hasValue() or (children().count() > id.count())

This structure is derived from Evidence

Summary

Mandatory: 10 elements(2 nested mandatory elements)
Must-Support: 3 elements
Prohibited: 2 elements

Structures

This structure refers to these other structures:

Slices

This structure defines the following Slices:

  • The element 1 is sliced based on the value of Evidence.variableDefinition
  • The element 1 is sliced based on the value of Evidence.statistic
  • The element 1 is sliced based on the value of Evidence.statistic.attributeEstimate
  • The element 1 is sliced based on the value of Evidence.statistic.modelCharacteristic

Maturity: 1

Differential View

This structure is derived from Evidence

NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence 0..* Evidence Single evidence bit
... Slices for variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
Slice: Unordered, Open by value:variableRole
.... variableDefinition:population 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... variableRole 1..1 code population | exposure | outcome | covariate
Required Pattern: population
..... observed 0..1 Reference(NetEffectContributions) Definition of the actual variable related to the statistic(s)
..... intended 0..0
.... variableDefinition:exposure 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... variableRole 1..1 code population | exposure | outcome | covariate
Required Pattern: exposure
..... comparatorCategory 1..1 string The reference value used for comparison
..... observed 0..1 Reference(GroupAssignment) Definition of the actual variable related to the statistic(s)
..... intended 0..0
... Slices for statistic 1..* BackboneElement Values and parameters for a single statistic
Slice: Unordered, Open by value:statisticType.coding
.... statistic:netEffect S 1..1 BackboneElement Values and parameters for a single statistic
..... statisticType
...... coding 1..1 Coding Code defined by a terminology system
Required Pattern: At least the following
....... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
....... code 1..1 code Symbol in syntax defined by the system
Fixed Value: STATO:0000424
....... display 1..1 string Representation defined by the system
Fixed Value: Risk Difference
..... Slices for attributeEstimate 1..* BackboneElement An attribute of the Statistic
Slice: Unordered, Open by value:type.coding
...... attributeEstimate:confidenceInterval S 1..1 BackboneElement An attribute of the Statistic
....... type
........ coding 1..1 Coding Code defined by a terminology system
Required Pattern: At least the following
......... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
......... code 1..1 code Symbol in syntax defined by the system
Fixed Value: STATO:0000196
......... display 1..1 string Representation defined by the system
Fixed Value: confidence interval
..... Slices for modelCharacteristic 1..* BackboneElement An aspect of the statistical model
Slice: Unordered, Open by value:code.coding
...... modelCharacteristic:netEffectAnalysis S 1..1 BackboneElement An aspect of the statistical model
....... code
........ coding 1..1 Coding Code defined by a terminology system
Required Pattern: At least the following
......... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
......... code 1..1 code Symbol in syntax defined by the system
Fixed Value: TBD:net-effect-analysis
......... display 1..1 string Representation defined by the system
Fixed Value: Net effect analysis

doco Documentation for this format

Key Elements View

NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence C 0..* Evidence Single evidence bit
cnl-0: Name should be usable as an identifier for the module by machine processing applications such as code generation
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... contained 0..* Resource Contained, inline Resources
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... Slices for variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
Slice: Unordered, Open by value:variableRole
.... variableDefinition:All Slices Content/Rules for all slices
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.

.... variableDefinition:population 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: population
..... observed Σ 0..1 Reference(NetEffectContributions) Definition of the actual variable related to the statistic(s)
.... variableDefinition:exposure 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: exposure
..... comparatorCategory 1..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(GroupAssignment) Definition of the actual variable related to the statistic(s)
... Slices for statistic 1..* BackboneElement Values and parameters for a single statistic
Slice: Unordered, Open by value:statisticType.coding
.... statistic:All Slices Content/Rules for all slices
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... statistic:netEffect S 1..1 BackboneElement Values and parameters for a single statistic
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... Slices for attributeEstimate 1..* BackboneElement An attribute of the Statistic
Slice: Unordered, Open by value:type.coding
...... attributeEstimate:All Slices Content/Rules for all slices
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... attributeEstimate:confidenceInterval S 1..1 BackboneElement An attribute of the Statistic
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... Slices for modelCharacteristic 1..* BackboneElement An aspect of the statistical model
Slice: Unordered, Open by value:code.coding
...... modelCharacteristic:All Slices Content/Rules for all slices
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... code 1..1 CodeableConcept Model specification
Binding: StatisticModelCode (extensible)
...... modelCharacteristic:netEffectAnalysis S 1..1 BackboneElement An aspect of the statistical model
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... code 1..1 CodeableConcept Model specification
Binding: StatisticModelCode (extensible)
........ coding 1..1 Coding Code defined by a terminology system

Required Pattern: At least the following
......... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
......... code 1..1 code Symbol in syntax defined by the system
Fixed Value: TBD:net-effect-analysis
......... display 1..1 string Representation defined by the system
Fixed Value: Net effect analysis

doco Documentation for this format

Terminology Bindings

PathConformanceValueSet / CodeURI
Evidence.statusrequiredPublicationStatus
http://hl7.org/fhir/ValueSet/publication-status|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.variableRolerequiredEvidenceVariableRole
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:population.variableRolerequiredPattern: population
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:exposure.variableRolerequiredPattern: exposure
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic:netEffectAnalysis.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard

Constraints

IdGradePath(s)DetailsRequirements
cnl-0warningEvidenceName should be usable as an identifier for the module by machine processing applications such as code generation
: name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$')
ele-1error**ALL** elementsAll FHIR elements must have a @value or children
: hasValue() or (children().count() > id.count())

Snapshot View

NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence C 0..* Evidence Single evidence bit
cnl-0: Name should be usable as an identifier for the module by machine processing applications such as code generation
... id Σ 0..1 id Logical id of this artifact
... meta Σ 0..1 Meta Metadata about the resource
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... language 0..1 code Language of the resource content
Binding: AllLanguages (required): IETF language tag for a human language

Additional BindingsPurpose
CommonLanguages Starter Set
... text 0..1 Narrative Text summary of the resource, for human interpretation
... contained 0..* Resource Contained, inline Resources
... extension 0..* Extension Additional content defined by implementations
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... url ΣC 0..1 uri Canonical identifier for this evidence, represented as a globally unique URI
cnl-1: URL should not contain | or # - these characters make processing canonical references problematic
... identifier Σ 0..* Identifier Additional identifier for the summary
... version Σ 0..1 string Business version of this summary
... versionAlgorithm[x] Σ 0..1 How to compare versions
Binding: VersionAlgorithm (extensible)
.... versionAlgorithmString string
.... versionAlgorithmCoding Coding
... name C 0..1 string Name for this summary (machine friendly)
... title Σ 0..1 string Name for this summary (human friendly)
... citeAs[x] 0..1 Citation for this evidence
.... citeAsReference Reference(Citation)
.... citeAsMarkdown markdown
... status ?!Σ 1..1 code draft | active | retired | unknown
Binding: PublicationStatus (required): The lifecycle status of an artifact.

... experimental 0..1 boolean For testing purposes, not real usage
... date Σ 0..1 dateTime Date last changed
... approvalDate 0..1 date When the summary was approved by publisher
... lastReviewDate 0..1 date When the summary was last reviewed by the publisher
... publisher Σ 0..1 string Name of the publisher/steward (organization or individual)
... contact Σ 0..* ContactDetail Contact details for the publisher
... author Σ 0..* ContactDetail Who authored the content
... editor 0..* ContactDetail Who edited the content
... reviewer 0..* ContactDetail Who reviewed the content
... endorser Σ 0..* ContactDetail Who endorsed the content
... useContext Σ 0..* UsageContext The context that the content is intended to support
... purpose 0..1 markdown Why this Evidence is defined
... copyright 0..1 markdown Use and/or publishing restrictions
... copyrightLabel 0..1 string Copyright holder and year(s)
... relatedArtifact 0..* RelatedArtifact Link or citation to artifact associated with the summary
... description 0..1 markdown Description of the particular summary
... assertion 0..1 markdown Declarative description of the Evidence
... note 0..* Annotation Footnotes and/or explanatory notes
... Slices for variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
Slice: Unordered, Open by value:variableRole
.... variableDefinition:All Slices Content/Rules for all slices
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.

..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 0..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(Group | EvidenceVariable) Definition of the actual variable related to the statistic(s)
..... intended 0..1 Reference(Group | EvidenceVariable) Definition of the intended variable related to the Evidence
..... directnessMatch 0..1 CodeableConcept low | moderate | high | exact
Binding: EvidenceDirectness (extensible): The quality of how direct the match is.

.... variableDefinition:population 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: population
..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 0..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(NetEffectContributions) Definition of the actual variable related to the statistic(s)
..... directnessMatch 0..1 CodeableConcept low | moderate | high | exact
Binding: EvidenceDirectness (extensible): The quality of how direct the match is.

.... variableDefinition:exposure 1..1 BackboneElement Evidence variable such as population, exposure, or outcome
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: exposure
..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 1..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(GroupAssignment) Definition of the actual variable related to the statistic(s)
..... directnessMatch 0..1 CodeableConcept low | moderate | high | exact
Binding: EvidenceDirectness (extensible): The quality of how direct the match is.

... synthesisType 0..1 CodeableConcept The method to combine studies
Binding: StatisticSynthesisType (extensible): Types of combining results from a body of evidence (e.g. summary data meta-analysis).

... studyDesign 0..* CodeableConcept The design of the study that produced this evidence
Binding: StudyDesign (extensible): This is a set of terms for study design characteristics.


... Slices for statistic 1..* BackboneElement Values and parameters for a single statistic
Slice: Unordered, Open by value:statisticType.coding
.... statistic:All Slices Content/Rules for all slices
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown Description of content
..... note 0..* Annotation Footnotes and/or explanatory notes
..... statisticType 0..1 CodeableConcept Type of statistic, e.g., relative risk
Binding: StatisticType (extensible)
..... category 0..1 CodeableConcept Associated category for categorical variable
..... quantity 0..1 Quantity Statistic value
..... numberOfEvents 0..1 unsignedInt The number of events associated with the statistic
..... numberAffected 0..1 unsignedInt The number of participants affected
..... sampleSize 0..1 BackboneElement Number of samples in the statistic
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... description 0..1 markdown Textual description of sample size for statistic
...... note 0..* Annotation Footnote or explanatory note about the sample size
...... numberOfStudies 0..1 unsignedInt Number of contributing studies
...... numberOfParticipants 0..1 unsignedInt Cumulative number of participants
...... knownDataCount 0..1 unsignedInt Number of participants with known results for measured variables
..... attributeEstimate 0..* BackboneElement An attribute of the Statistic
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... description 0..1 markdown Textual description of the attribute estimate
...... note 0..* Annotation Footnote or explanatory note about the estimate
...... type 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value
Binding: AttributeEstimateType (extensible)
...... quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
...... level 0..1 decimal Level of confidence interval, e.g., 0.95 for 95% confidence interval
...... range 0..1 Range Lower and upper bound values of the attribute estimate
...... attributeEstimate 0..* See attributeEstimate (Evidence) A nested attribute estimate; which is the attribute estimate of an attribute estimate
..... modelCharacteristic 0..* BackboneElement An aspect of the statistical model
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... code 1..1 CodeableConcept Model specification
Binding: StatisticModelCode (extensible)
...... value[x] 0..1 The specific value (when paired with code)
....... valueQuantity Quantity(SimpleQuantity)
....... valueRange Range
....... valueCodeableConcept CodeableConcept
...... intended 0..1 boolean The plan for analysis
...... applied 0..1 boolean The analysis that was applied
...... variable 0..* BackboneElement A variable adjusted for in the adjusted analysis
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... variableDefinition 1..1 Reference(Group | EvidenceVariable) Description of the variable
....... handling 0..1 code continuous | dichotomous | ordinal | polychotomous
Binding: EvidenceVariableHandling (required)
....... valueCategory 0..* CodeableConcept Description for grouping of ordinal or polychotomous variables
....... valueQuantity 0..* Quantity Discrete value for grouping of ordinal or polychotomous variables
....... valueRange 0..* Range Range of values for grouping of ordinal or polychotomous variables
...... attribute 0..* See attributeEstimate (Evidence) An attribute of the statistic used as a model characteristic
.... statistic:netEffect S 1..1 BackboneElement Values and parameters for a single statistic
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown Description of content
..... note 0..* Annotation Footnotes and/or explanatory notes
..... statisticType 0..1 CodeableConcept Type of statistic, e.g., relative risk
Binding: StatisticType (extensible)
...... id 0..1 id Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
...... coding 1..1 Coding Code defined by a terminology system

Required Pattern: At least the following
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
....... version 0..1 string Version of the system - if relevant
....... code 1..1 code Symbol in syntax defined by the system
Fixed Value: STATO:0000424
....... display 1..1 string Representation defined by the system
Fixed Value: Risk Difference
....... userSelected 0..1 boolean If this coding was chosen directly by the user
...... text 0..1 string Plain text representation of the concept
..... category 0..1 CodeableConcept Associated category for categorical variable
..... quantity 0..1 Quantity Statistic value
..... numberOfEvents 0..1 unsignedInt The number of events associated with the statistic
..... numberAffected 0..1 unsignedInt The number of participants affected
..... sampleSize 0..1 BackboneElement Number of samples in the statistic
...... id 0..1 string Unique id for inter-element referencing
...... extension 0..* Extension Additional content defined by implementations
...... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
...... description 0..1 markdown Textual description of sample size for statistic
...... note 0..* Annotation Footnote or explanatory note about the sample size
...... numberOfStudies 0..1 unsignedInt Number of contributing studies
...... numberOfParticipants 0..1 unsignedInt Cumulative number of participants
...... knownDataCount 0..1 unsignedInt Number of participants with known results for measured variables
..... Slices for attributeEstimate 1..* BackboneElement An attribute of the Statistic
Slice: Unordered, Open by value:type.coding
...... attributeEstimate:All Slices Content/Rules for all slices
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... description 0..1 markdown Textual description of the attribute estimate
....... note 0..* Annotation Footnote or explanatory note about the estimate
....... type 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value
Binding: AttributeEstimateType (extensible)
....... quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
....... level 0..1 decimal Level of confidence interval, e.g., 0.95 for 95% confidence interval
....... range 0..1 Range Lower and upper bound values of the attribute estimate
....... attributeEstimate 0..* See attributeEstimate (Evidence) A nested attribute estimate; which is the attribute estimate of an attribute estimate
...... attributeEstimate:confidenceInterval S 1..1 BackboneElement An attribute of the Statistic
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... description 0..1 markdown Textual description of the attribute estimate
....... note 0..* Annotation Footnote or explanatory note about the estimate
....... type 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value
Binding: AttributeEstimateType (extensible)
........ id 0..1 id Unique id for inter-element referencing
........ extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
........ coding 1..1 Coding Code defined by a terminology system

Required Pattern: At least the following
......... id 0..1 string Unique id for inter-element referencing
......... extension 0..* Extension Additional content defined by implementations
......... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
......... version 0..1 string Version of the system - if relevant
......... code 1..1 code Symbol in syntax defined by the system
Fixed Value: STATO:0000196
......... display 1..1 string Representation defined by the system
Fixed Value: confidence interval
......... userSelected 0..1 boolean If this coding was chosen directly by the user
........ text 0..1 string Plain text representation of the concept
....... quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
....... level 0..1 decimal Level of confidence interval, e.g., 0.95 for 95% confidence interval
....... range 0..1 Range Lower and upper bound values of the attribute estimate
....... attributeEstimate 0..* See attributeEstimate (Evidence) A nested attribute estimate; which is the attribute estimate of an attribute estimate
..... Slices for modelCharacteristic 1..* BackboneElement An aspect of the statistical model
Slice: Unordered, Open by value:code.coding
...... modelCharacteristic:All Slices Content/Rules for all slices
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... code 1..1 CodeableConcept Model specification
Binding: StatisticModelCode (extensible)
....... value[x] 0..1 The specific value (when paired with code)
........ valueQuantity Quantity(SimpleQuantity)
........ valueRange Range
........ valueCodeableConcept CodeableConcept
....... intended 0..1 boolean The plan for analysis
....... applied 0..1 boolean The analysis that was applied
....... variable 0..* BackboneElement A variable adjusted for in the adjusted analysis
........ id 0..1 string Unique id for inter-element referencing
........ extension 0..* Extension Additional content defined by implementations
........ modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
........ variableDefinition 1..1 Reference(Group | EvidenceVariable) Description of the variable
........ handling 0..1 code continuous | dichotomous | ordinal | polychotomous
Binding: EvidenceVariableHandling (required)
........ valueCategory 0..* CodeableConcept Description for grouping of ordinal or polychotomous variables
........ valueQuantity 0..* Quantity Discrete value for grouping of ordinal or polychotomous variables
........ valueRange 0..* Range Range of values for grouping of ordinal or polychotomous variables
....... attribute 0..* See attributeEstimate (Evidence) An attribute of the statistic used as a model characteristic
...... modelCharacteristic:netEffectAnalysis S 1..1 BackboneElement An aspect of the statistical model
....... id 0..1 string Unique id for inter-element referencing
....... extension 0..* Extension Additional content defined by implementations
....... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
....... code 1..1 CodeableConcept Model specification
Binding: StatisticModelCode (extensible)
........ id 0..1 id Unique id for inter-element referencing
........ extension 0..* Extension Additional content defined by implementations
Slice: Unordered, Open by value:url
........ coding 1..1 Coding Code defined by a terminology system

Required Pattern: At least the following
......... id 0..1 string Unique id for inter-element referencing
......... extension 0..* Extension Additional content defined by implementations
......... system 1..1 uri Identity of the terminology system
Fixed Value: https://fevir.net/resources/CodeSystem/181513
......... version 0..1 string Version of the system - if relevant
......... code 1..1 code Symbol in syntax defined by the system
Fixed Value: TBD:net-effect-analysis
......... display 1..1 string Representation defined by the system
Fixed Value: Net effect analysis
......... userSelected 0..1 boolean If this coding was chosen directly by the user
........ text 0..1 string Plain text representation of the concept
....... value[x] 0..1 The specific value (when paired with code)
........ valueQuantity Quantity(SimpleQuantity)
........ valueRange Range
........ valueCodeableConcept CodeableConcept
....... intended 0..1 boolean The plan for analysis
....... applied 0..1 boolean The analysis that was applied
....... variable 0..* BackboneElement A variable adjusted for in the adjusted analysis
........ id 0..1 string Unique id for inter-element referencing
........ extension 0..* Extension Additional content defined by implementations
........ modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
........ variableDefinition 1..1 Reference(Group | EvidenceVariable) Description of the variable
........ handling 0..1 code continuous | dichotomous | ordinal | polychotomous
Binding: EvidenceVariableHandling (required)
........ valueCategory 0..* CodeableConcept Description for grouping of ordinal or polychotomous variables
........ valueQuantity 0..* Quantity Discrete value for grouping of ordinal or polychotomous variables
........ valueRange 0..* Range Range of values for grouping of ordinal or polychotomous variables
....... attribute 0..* See attributeEstimate (Evidence) An attribute of the statistic used as a model characteristic
... certainty 0..* BackboneElement Certainty or quality of the evidence
.... id 0..1 string Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
.... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... description 0..1 markdown Textual description of certainty
.... note 0..* Annotation Footnotes and/or explanatory notes
.... type 0..1 CodeableConcept Aspect of certainty being rated
Binding: EvidenceCertaintyType (extensible): The aspect of quality, confidence, or certainty.

.... rating 0..1 CodeableConcept Assessment or judgement of the aspect
Binding: EvidenceCertaintyRating (extensible): The assessment of quality, confidence, or certainty.

.... rater 0..1 string Individual or group who did the rating
.... subcomponent 0..* See certainty (Evidence) A domain or subdomain of certainty

doco Documentation for this format

Terminology Bindings

PathConformanceValueSet / CodeURI
Evidence.languagerequiredAllLanguages
http://hl7.org/fhir/ValueSet/all-languages|6.0.0-ballot2
from the FHIR Standard
Evidence.versionAlgorithm[x]extensibleVersionAlgorithm
http://hl7.org/fhir/ValueSet/version-algorithm
from the FHIR Standard
Evidence.statusrequiredPublicationStatus
http://hl7.org/fhir/ValueSet/publication-status|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.variableRolerequiredEvidenceVariableRole
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.variableDefinition.directnessMatchextensibleEvidenceDirectness
http://terminology.hl7.org/ValueSet/directness
Evidence.variableDefinition:population.variableRolerequiredPattern: population
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:population.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.variableDefinition:population.directnessMatchextensibleEvidenceDirectness
http://terminology.hl7.org/ValueSet/directness
Evidence.variableDefinition:exposure.variableRolerequiredPattern: exposure
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:exposure.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.variableDefinition:exposure.directnessMatchextensibleEvidenceDirectness
http://terminology.hl7.org/ValueSet/directness
Evidence.synthesisTypeextensibleStatisticSynthesisType
http://terminology.hl7.org/ValueSet/synthesis-type
Evidence.studyDesignextensibleStudyDesign
http://hl7.org/fhir/ValueSet/study-design
from the FHIR Standard
Evidence.statistic.statisticTypeextensibleStatisticType
http://hl7.org/fhir/ValueSet/statistic-type
from the FHIR Standard
Evidence.statistic.attributeEstimate.typeextensibleAttributeEstimateType
http://hl7.org/fhir/ValueSet/attribute-estimate-type
from the FHIR Standard
Evidence.statistic.modelCharacteristic.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard
Evidence.statistic.modelCharacteristic.variable.handlingrequiredEvidenceVariableHandling
http://hl7.org/fhir/ValueSet/variable-handling|6.0.0-ballot2
from the FHIR Standard
Evidence.statistic:netEffect.statisticTypeextensibleStatisticType
http://hl7.org/fhir/ValueSet/statistic-type
from the FHIR Standard
Evidence.statistic:netEffect.attributeEstimate.typeextensibleAttributeEstimateType
http://hl7.org/fhir/ValueSet/attribute-estimate-type
from the FHIR Standard
Evidence.statistic:netEffect.attributeEstimate:confidenceInterval.typeextensibleAttributeEstimateType
http://hl7.org/fhir/ValueSet/attribute-estimate-type
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic.variable.handlingrequiredEvidenceVariableHandling
http://hl7.org/fhir/ValueSet/variable-handling|6.0.0-ballot2
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic:netEffectAnalysis.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard
Evidence.statistic:netEffect.modelCharacteristic:netEffectAnalysis.variable.handlingrequiredEvidenceVariableHandling
http://hl7.org/fhir/ValueSet/variable-handling|6.0.0-ballot2
from the FHIR Standard
Evidence.certainty.typeextensibleEvidenceCertaintyType
http://hl7.org/fhir/ValueSet/certainty-type
from the FHIR Standard
Evidence.certainty.ratingextensibleEvidenceCertaintyRating
http://hl7.org/fhir/ValueSet/certainty-rating
from the FHIR Standard

Constraints

IdGradePath(s)DetailsRequirements
cnl-0warningEvidenceName should be usable as an identifier for the module by machine processing applications such as code generation
: name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$')
cnl-1warningEvidence.urlURL should not contain | or # - these characters make processing canonical references problematic
: exists() implies matches('^[^|# ]+$')
ele-1error**ALL** elementsAll FHIR elements must have a @value or children
: hasValue() or (children().count() > id.count())

This structure is derived from Evidence

Summary

Mandatory: 10 elements(2 nested mandatory elements)
Must-Support: 3 elements
Prohibited: 2 elements

Structures

This structure refers to these other structures:

Slices

This structure defines the following Slices:

  • The element 1 is sliced based on the value of Evidence.variableDefinition
  • The element 1 is sliced based on the value of Evidence.statistic
  • The element 1 is sliced based on the value of Evidence.statistic.attributeEstimate
  • The element 1 is sliced based on the value of Evidence.statistic.modelCharacteristic

Maturity: 1

 

Other representations of profile: CSV, Excel, Schematron